{"id":"https://openalex.org/W2039028985","doi":"https://doi.org/10.1097/00007890-199801270-00002","title":"FAS LIGAND GENE TRANSFER TO RENAL ALLOGRAFTS IN RATS","display_name":"FAS LIGAND GENE TRANSFER TO RENAL ALLOGRAFTS IN RATS","publication_year":1998,"publication_date":"1998-01-01","ids":{"openalex":"https://openalex.org/W2039028985","doi":"https://doi.org/10.1097/00007890-199801270-00002","mag":"2039028985","pmid":"https://pubmed.ncbi.nlm.nih.gov/9458007"},"language":"en","primary_location":{"id":"doi:10.1097/00007890-199801270-00002","doi":"https://doi.org/10.1097/00007890-199801270-00002","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00007890-199801270-00002","pdf_url":null,"source":{"id":"https://openalex.org/S11564597","display_name":"Transplantation","issn_l":"0041-1337","issn":["0041-1337","1534-6080"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028222659","display_name":"Kim Swenson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1282927834","display_name":"Cedars-Sinai Medical Center","ror":"https://ror.org/02pammg90","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1282927834"]},{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]},{"id":"https://openalex.org/I2799798094","display_name":"UCLA Health","ror":"https://ror.org/01d88se56","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799798094"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kim M. Swenson","raw_affiliation_strings":["Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90095, USA","Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine","The Center for Liver Diseases and Transplantation, Department of Surgery, Cedars-Sinai Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine, Cedars-Sinai Medical Center, Los Angeles, California 90095, USA","institution_ids":["https://openalex.org/I1282927834","https://openalex.org/I161318765","https://openalex.org/I2799798094"]},{"raw_affiliation_string":"Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"The Center for Liver Diseases and Transplantation, Department of Surgery, Cedars-Sinai Medical Center","institution_ids":["https://openalex.org/I1282927834"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045209569","display_name":"Bibo Ke","orcid":"https://orcid.org/0000-0002-1885-1538","observed_orcids":["https://orcid.org/0000-0002-1885-1538"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bibo Ke","raw_affiliation_strings":["Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113581905","display_name":"Tao Wang","orcid":"https://orcid.org/0000-0001-7979-6707","observed_orcids":["https://orcid.org/0000-0001-7979-6707","https://orcid.org/0009-0008-9931-4531"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tao Wang","raw_affiliation_strings":["Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021747600","display_name":"Jay S. Markowitz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jay S. Markowitz","raw_affiliation_strings":["Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042336898","display_name":"Melinda A. Maggard","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melinda A. Maggard","raw_affiliation_strings":["Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083017858","display_name":"Gerald S. Spear","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204250578","display_name":"University of California, Irvine","ror":"https://ror.org/04gyf1771","country_code":"US","type":"education","lineage":["https://openalex.org/I204250578"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gerald S. Spear","raw_affiliation_strings":["Department of Pathology, UCI School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, UCI School of Medicine","institution_ids":["https://openalex.org/I204250578"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060036882","display_name":"David K. Imagawa","orcid":"https://orcid.org/0000-0002-5947-5313","observed_orcids":["https://orcid.org/0000-0002-5947-5313"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David K. Imagawa","raw_affiliation_strings":["Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058244592","display_name":"John A. Goss","orcid":"https://orcid.org/0000-0002-2794-1156","observed_orcids":["https://orcid.org/0000-0002-2794-1156"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John A. Goss","raw_affiliation_strings":["Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075909338","display_name":"Ronald W. Busuttil","orcid":"https://orcid.org/0000-0001-8157-1531","observed_orcids":["https://orcid.org/0000-0001-8157-1531"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ronald W. Busuttil","raw_affiliation_strings":["Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110238036","display_name":"Philip Seu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Philip Seu","raw_affiliation_strings":["Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine","Philip Seu, M.D., Department of Surgery, UCLA School of Medicine, CHS 77-13, 10833 Le Conte Avenue, Los Angeles, CA 90095"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dumont-UCLA Transplant Center, Department of Surgery, UCLA School of Medicine","institution_ids":["https://openalex.org/I161318765"]},{"raw_affiliation_string":"Philip Seu, M.D., Department of Surgery, UCLA School of Medicine, CHS 77-13, 10833 Le Conte Avenue, Los Angeles, CA 90095","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5110238036"],"corresponding_institution_ids":["https://openalex.org/I161318765"],"apc_list":null,"apc_paid":null,"fwci":11.2597,"has_fulltext":false,"cited_by_count":102,"citation_normalized_percentile":{"value":0.99091344,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"65","issue":"2","first_page":"155","last_page":"160"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.6718999743461609,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.6718999743461609,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.13130000233650208,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.1054999977350235,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fas-ligand","display_name":"Fas ligand","score":0.9990000128746033},{"id":"https://openalex.org/keywords/kidney-allograft-rejection","display_name":"renal allograft rejection","score":0.8190000057220459},{"id":"https://openalex.org/keywords/adenoviral-gene-transfer","display_name":"adenoviral gene transfer","score":0.8259999752044678},{"id":"https://openalex.org/keywords/replication-deficient-adenovirus","display_name":"replication-defective adenovirus","score":0.8180000185966492},{"id":"https://openalex.org/keywords/allograft-survival","display_name":"allograft survival","score":0.7329999804496765},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.6880000233650208},{"id":"https://openalex.org/keywords/fas","display_name":"Fas","score":0.734000027179718},{"id":"https://openalex.org/keywords/kidney-transplantation","display_name":"kidney transplantation","score":0.7020000219345093},{"id":"https://openalex.org/keywords/immune-privilege","display_name":"immune privilege","score":0.6029999852180481},{"id":"https://openalex.org/keywords/gene-therapy","display_name":"gene therapy","score":0.46799999475479126}],"concepts":[{"id":"https://openalex.org/C66008609","wikidata":"https://www.wikidata.org/wiki/Q14866113","display_name":"Fas ligand","level":4,"score":0.7175910472869873},{"id":"https://openalex.org/C3018928802","wikidata":"https://www.wikidata.org/wiki/Q83185","display_name":"Gene transfer","level":3,"score":0.6810400485992432},{"id":"https://openalex.org/C116569031","wikidata":"https://www.wikidata.org/wiki/Q899107","display_name":"Ligand (biochemistry)","level":3,"score":0.526596188545227},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4735112488269806},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3970223069190979},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.339446485042572},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.33020561933517456},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3285413980484009},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2474164366722107},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2151411771774292},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.18387669324874878},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.13100668787956238},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.048445701599121094}],"mesh":[{"descriptor_ui":"D000256","descriptor_name":"Adenoviridae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003602","descriptor_name":"Cytotoxicity, Immunologic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006084","descriptor_name":"Graft Rejection","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D006085","descriptor_name":"Graft Survival","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D006085","descriptor_name":"Graft Survival","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006367","descriptor_name":"HeLa Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008562","descriptor_name":"Membrane Glycoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011917","descriptor_name":"Rats, Inbred Lew","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011920","descriptor_name":"Rats, Inbred WF","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014161","descriptor_name":"Transduction, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014184","descriptor_name":"Transplantation, Homologous","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D014184","descriptor_name":"Transplantation, Homologous","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D016030","descriptor_name":"Kidney Transplantation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D016030","descriptor_name":"Kidney Transplantation","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018014","descriptor_name":"Gene Transfer Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053222","descriptor_name":"Fas Ligand Protein","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/00007890-199801270-00002","doi":"https://doi.org/10.1097/00007890-199801270-00002","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00007890-199801270-00002","pdf_url":null,"source":{"id":"https://openalex.org/S11564597","display_name":"Transplantation","issn_l":"0041-1337","issn":["0041-1337","1534-6080"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310318547","host_organization_name":"Wolters Kluwer","host_organization_lineage":["https://openalex.org/P4310318547"],"host_organization_lineage_names":["Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation","raw_type":"journal-article"},{"id":"pmid:9458007","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9458007","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transplantation","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9476000070571899,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"score":0.7599999904632568,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W143113709","https://openalex.org/W245228226","https://openalex.org/W1482540117","https://openalex.org/W1671694443","https://openalex.org/W1965372133","https://openalex.org/W1974612446","https://openalex.org/W1978018492","https://openalex.org/W1991212304","https://openalex.org/W1992060545","https://openalex.org/W1999425834","https://openalex.org/W2002733542","https://openalex.org/W2004645606","https://openalex.org/W2012209476","https://openalex.org/W2016198585","https://openalex.org/W2027492749","https://openalex.org/W2034325959","https://openalex.org/W2037804577","https://openalex.org/W2045796964","https://openalex.org/W2076229621","https://openalex.org/W2078901980","https://openalex.org/W2086313080","https://openalex.org/W2102150129","https://openalex.org/W2127993518","https://openalex.org/W2143612925","https://openalex.org/W2168747001"],"related_works":["https://openalex.org/W2391620242","https://openalex.org/W2379912737","https://openalex.org/W2036546908","https://openalex.org/W4233765055","https://openalex.org/W2748788671","https://openalex.org/W4250396378","https://openalex.org/W146276945","https://openalex.org/W3029969485","https://openalex.org/W2106218580","https://openalex.org/W2379172001"],"abstract_inverted_index":{"BACKGROUND:":[0],"Fas":[1],"ligand":[2],"(FasL)":[3],"induces":[4],"apoptosis":[5],"of":[6,59,92,102,122,153,184],"cells":[7],"bearing":[8],"its":[9],"receptor":[10],"Fas,":[11],"and":[12,22,24,72,104,117,137,148,164,177],"has":[13],"been":[14],"shown":[15],"to":[16],"be":[17],"important":[18],"in":[19,25,80,168,196],"T-cell":[20],"development":[21],"regulation":[23],"immune":[26],"privilege.":[27],"We":[28],"hypothesized":[29],"that":[30],"FasL":[31,44,131,140,165,213,216],"expression":[32,54,132],"by":[33,57,143,174],"renal":[34,188,221],"allografts":[35,127,155,171,189],"might":[36],"provide":[37],"protection":[38],"from":[39],"rejection.":[40],"METHODS:":[41],"The":[42],"murine":[43],"cDNA":[45],"was":[46,55,97,114,172,190],"cloned":[47],"into":[48],"a":[49,134],"replication-defective":[50],"adenovirus":[51],"(AdV-FasL).":[52],"Protein":[53],"confirmed":[56,173],"immunostaining":[58],"AdV-FasL-transduced":[60,154,170,187],"HeLa":[61],"cells.":[62],"Allogeneic":[63],"kidney":[64,96],"transplants":[65],"were":[66,78,124,128],"performed":[67],"between":[68],"WF":[69],"(RT1u)":[70],"donors":[71],"Lewis":[73],"(RT1)":[74],"recipients.":[75],"Donor":[76],"kidneys":[77,210],"perfused":[79],"situ":[81],"with":[82,186,211],"saline":[83],"alone":[84],"(control),":[85],"or":[86,109],"9":[87],"x":[88],"10(9)":[89],"plaque-forming":[90],"units":[91],"AdV-FasL.":[93],"One":[94],"native":[95],"removed":[98],"at":[99,107],"the":[100,105,115,169,212],"time":[101],"transplant":[103,123],"other":[106],"6":[108],"7":[110,120],"days.":[111],"Uremic":[112],"death":[113],"endpoint,":[116],"deaths":[118],"within":[119],"days":[121,192,195],"excluded.":[125],"Transduced":[126],"stained":[129],"for":[130,139],"using":[133],"monoclonal":[135],"antibody":[136],"tested":[138],"mRNA":[141,166],"production":[142,167],"reverse":[144,178],"transcriptase-polymerase":[145,179],"chain":[146,180],"reaction":[147],"Northern":[149,175],"blotting.":[150],"RESULTS:":[151],"Immunostaining":[152],"demonstrated":[156],"efficient":[157],"gene":[158,217],"transfer":[159,218],"lasting":[160],"approximately":[161],"2":[162],"weeks,":[163],"blotting":[176],"reaction.":[181],"Mean":[182],"survival":[183],"animals":[185,198],"27.8":[191],"vs.":[193],"11.6":[194],"control":[197],"(P":[199],"<":[200],"0.05).":[201],"CONCLUSIONS:":[202],"(1)":[203],"Adenoviral":[204],"vectors":[205],"can":[206],"successfully":[207],"transduce":[208],"rat":[209,220],"cDNA.":[214],"(2)":[215],"prolongs":[219],"allograft":[222],"survival.":[223]},"counts_by_year":[{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}