{"id":"https://openalex.org/W2038437468","doi":"https://doi.org/10.1002/depr.3050020502","title":"Sexual dysfunction and antidepressants","display_name":"Sexual dysfunction and antidepressants","publication_year":1994,"publication_date":"1994-01-01","ids":{"openalex":"https://openalex.org/W2038437468","doi":"https://doi.org/10.1002/depr.3050020502","mag":"2038437468","pmid":"https://pubmed.ncbi.nlm.nih.gov/9019472"},"language":"en","primary_location":{"id":"doi:10.1002/depr.3050020502","doi":"https://doi.org/10.1002/depr.3050020502","is_oa":false,"landing_page_url":"https://doi.org/10.1002/depr.3050020502","pdf_url":null,"source":{"id":"https://openalex.org/S4394736653","display_name":"Depression","issn_l":"1062-6417","issn":["1062-6417","1522-7162"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Depression","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101864584","display_name":"Jonathan R. T. Davidson","orcid":"https://orcid.org/0000-0002-8387-8913","observed_orcids":["https://orcid.org/0000-0002-8387-8913"]},"institutions":[{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jonathan R. T. Davidson","raw_affiliation_strings":["Department of Psychiatry, Duke University Medical Center, Durham, NC 27710"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Duke University Medical Center, Durham, NC 27710","institution_ids":["https://openalex.org/I4210126298"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5101864584"],"corresponding_institution_ids":["https://openalex.org/I4210126298"],"apc_list":null,"apc_paid":null,"fwci":1.1857,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.77418123,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"2","issue":"5","first_page":"233","last_page":"240"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10459","display_name":"Sexual function and dysfunction studies","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10459","display_name":"Sexual function and dysfunction studies","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/antidepressant-induced-sexual-dysfunction","display_name":"antidepressant-induced sexual dysfunction","score":0.9330000281333923},{"id":"https://openalex.org/keywords/sexual-dysfunction","display_name":"sexual dysfunction","score":0.6650000214576721},{"id":"https://openalex.org/keywords/bupropion","display_name":"bupropion","score":0.8220000267028809},{"id":"https://openalex.org/keywords/moclobemide","display_name":"moclobemide","score":0.9900000095367432},{"id":"https://openalex.org/keywords/trazodone","display_name":"trazodone","score":0.9990000128746033},{"id":"https://openalex.org/keywords/selective-serotonin-reuptake-inhibitors","display_name":"selective serotonin reuptake inhibitors","score":0.996999979019165},{"id":"https://openalex.org/keywords/venlafaxine","display_name":"venlafaxine","score":0.9629999995231628},{"id":"https://openalex.org/keywords/tricyclic-antidepressants","display_name":"tricyclic antidepressants","score":0.9980000257492065},{"id":"https://openalex.org/keywords/monoamine-oxidase-inhibitors","display_name":"monoamine oxidase inhibitors","score":0.9829999804496765},{"id":"https://openalex.org/keywords/adverse-drug-reactions","display_name":"adverse drug reactions","score":0.6460000276565552}],"concepts":[{"id":"https://openalex.org/C2779908668","wikidata":"https://www.wikidata.org/wiki/Q834280","display_name":"Bupropion","level":3,"score":0.8879170417785645},{"id":"https://openalex.org/C2780980600","wikidata":"https://www.wikidata.org/wiki/Q411457","display_name":"Trazodone","level":4,"score":0.7592747211456299},{"id":"https://openalex.org/C2778093883","wikidata":"https://www.wikidata.org/wiki/Q1137463","display_name":"Sexual dysfunction","level":2,"score":0.7086225152015686},{"id":"https://openalex.org/C2780237459","wikidata":"https://www.wikidata.org/wiki/Q421934","display_name":"Moclobemide","level":4,"score":0.6988610029220581},{"id":"https://openalex.org/C2779177272","wikidata":"https://www.wikidata.org/wiki/Q76560","display_name":"Antidepressant","level":3,"score":0.6238820552825928},{"id":"https://openalex.org/C2776466888","wikidata":"https://www.wikidata.org/wiki/Q898407","display_name":"Venlafaxine","level":4,"score":0.6166919469833374},{"id":"https://openalex.org/C2780250439","wikidata":"https://www.wikidata.org/wiki/Q423288","display_name":"Desipramine","level":4,"score":0.548528254032135},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5475640296936035},{"id":"https://openalex.org/C2779207875","wikidata":"https://www.wikidata.org/wiki/Q5887","display_name":"Orgasm","level":3,"score":0.52157062292099},{"id":"https://openalex.org/C2776466505","wikidata":"https://www.wikidata.org/wiki/Q385555","display_name":"Hamilton Rating Scale for Depression","level":4,"score":0.5167107582092285},{"id":"https://openalex.org/C2775871022","wikidata":"https://www.wikidata.org/wiki/Q7458776","display_name":"Sexual function","level":2,"score":0.4902835190296173},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.48349669575691223},{"id":"https://openalex.org/C2781081902","wikidata":"https://www.wikidata.org/wiki/Q3539074","display_name":"Tricyclic","level":2,"score":0.46182185411453247},{"id":"https://openalex.org/C2780051608","wikidata":"https://www.wikidata.org/wiki/Q42844","display_name":"Major depressive disorder","level":3,"score":0.4522349238395691},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.441081166267395},{"id":"https://openalex.org/C2779419675","wikidata":"https://www.wikidata.org/wiki/Q416632","display_name":"Nefazodone","level":5,"score":0.42222729325294495},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.40115755796432495},{"id":"https://openalex.org/C2776134451","wikidata":"https://www.wikidata.org/wiki/Q422244","display_name":"Fluoxetine","level":4,"score":0.3900197148323059},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3416607975959778},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3244364559650421},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.17390701174736023},{"id":"https://openalex.org/C2775864247","wikidata":"https://www.wikidata.org/wiki/Q167934","display_name":"Serotonin","level":3,"score":0.1464490294456482},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.14038366079330444},{"id":"https://openalex.org/C2777843972","wikidata":"https://www.wikidata.org/wiki/Q2462253","display_name":"Smoking cessation","level":2,"score":0.0},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000928","descriptor_name":"Antidepressive Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true},{"descriptor_ui":"D000928","descriptor_name":"Antidepressive Agents","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000928","descriptor_name":"Antidepressive Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007989","descriptor_name":"Libido","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010817","descriptor_name":"Physician-Patient Relations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012725","descriptor_name":"Sexual Behavior","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D012725","descriptor_name":"Sexual Behavior","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D020018","descriptor_name":"Sexual Dysfunctions, Psychological","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":true},{"descriptor_ui":"D020018","descriptor_name":"Sexual Dysfunctions, Psychological","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D020018","descriptor_name":"Sexual Dysfunctions, Psychological","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1002/depr.3050020502","doi":"https://doi.org/10.1002/depr.3050020502","is_oa":false,"landing_page_url":"https://doi.org/10.1002/depr.3050020502","pdf_url":null,"source":{"id":"https://openalex.org/S4394736653","display_name":"Depression","issn_l":"1062-6417","issn":["1062-6417","1522-7162"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Depression","raw_type":"journal-article"},{"id":"pmid:9019472","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9019472","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical psychiatry","raw_type":"Conference Proceedings"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W91369657","https://openalex.org/W142054525","https://openalex.org/W146500496","https://openalex.org/W177753408","https://openalex.org/W1609635846","https://openalex.org/W1642862840","https://openalex.org/W1971067412","https://openalex.org/W1992493700","https://openalex.org/W1999036944","https://openalex.org/W2021332565","https://openalex.org/W2026113991","https://openalex.org/W2053503259","https://openalex.org/W2054664777","https://openalex.org/W2085621114","https://openalex.org/W2089797301","https://openalex.org/W2090881323","https://openalex.org/W2098644261","https://openalex.org/W2098900616","https://openalex.org/W2105127096","https://openalex.org/W2108708894","https://openalex.org/W2114613490","https://openalex.org/W2139890332","https://openalex.org/W2146842058","https://openalex.org/W2278135747","https://openalex.org/W2285469441","https://openalex.org/W2397888462","https://openalex.org/W2399463262","https://openalex.org/W2401316413","https://openalex.org/W2410359532","https://openalex.org/W2412135395","https://openalex.org/W2412172055","https://openalex.org/W4234580850","https://openalex.org/W4297687375"],"related_works":["https://openalex.org/W2329737710","https://openalex.org/W2019656158","https://openalex.org/W1994717858","https://openalex.org/W1952442899","https://openalex.org/W2028783233","https://openalex.org/W2171466849","https://openalex.org/W4401920161","https://openalex.org/W2612380354","https://openalex.org/W1976111096","https://openalex.org/W164104107"],"abstract_inverted_index":{"Abstract":[0],"Antidepressants":[1],"can":[2],"interfere":[3],"with":[4,93,127],"sexual":[5,46,88,130,161,166],"desire,":[6],"arousal,":[7],"or":[8,143,177],"orgasm.":[9],"Frequency":[10,41],"estimates":[11,42],"vary":[12],"considerably":[13],"and":[14,35,63,72,96,105,107,112,151,154,199],"are":[15,156,169,178],"likely":[16],"to":[17,134,184,192],"be":[18],"influenced":[19],"by":[20],"methods":[21],"of":[22,30,37,43,53,129,188,204],"assessment,":[23],"drug":[24,82],"type,":[25],"diagnostic":[26],"group,":[27],"dose,":[28],"length":[29],"treatment,":[31],"baseline":[32],"depressive":[33],"status,":[34],"inclusion":[36],"a":[38,75,189],"placebo":[39],"condition.":[40],"antidepressant":[44,205],"induced":[45],"dysfunction":[47,89,131],"were":[48,67],"reviewed":[49],"in":[50,69,180],"three":[51],"sets":[52],"data:":[54],"Physicians'":[55],"Desk":[56],"Reference":[57],"(PDR)":[58],"product":[59],"monograph,":[60],"placebo\u2010controlled":[61],"trials,":[62,123],"uncontrolled":[64,122],"reports.":[65],"Rates":[66],"lowest":[68,91],"the":[70,81,202],"PDR":[71],"highest":[73,108],"when":[74,132],"structured":[76],"rating":[77],"was":[78,90,125],"used.":[79],"Among":[80],"groups,":[83],"from":[84,141],"all":[85],"those":[86],"sources,":[87],"overall":[92],"bupropion,":[94],"moclobemide,":[95],"trazodone,":[97],"intermediate":[98],"for":[99,109,160,173],"selective":[100],"serotonin":[101],"reuptake":[102],"inhibitors":[103],"(SSRIs)":[104],"venlafaxine,":[106],"tricyclic":[110],"(TCA)":[111],"first":[113],"generation":[114],"monoamine":[115],"oxidase":[116],"inhibitor":[117],"(MAOI)":[118],"drugs.":[119,145,206],"In":[120],"open,":[121],"bupropion":[124],"associated":[126],"disappearance":[128],"given":[133],"patients":[135],"who":[136],"exhibited":[137],"this":[138],"side":[139,162],"effect":[140],"TCA":[142],"SSRI":[144],"This":[146],"review":[147],"suggests":[148],"that":[149],"men":[150],"women,":[152],"depressives":[153],"non\u2010depressives,":[155],"both":[157],"at":[158],"risk":[159],"effects.":[163],"Currently":[164],"available":[165],"function":[167],"scales":[168],"either":[170],"too":[171],"complex":[172],"routine":[174],"clinical":[175],"use,":[176,193],"limited":[179],"scope":[181],"(e.g.,":[182],"restricted":[183],"males":[185],"only).":[186],"Availability":[187],"simple,":[190],"easy":[191],"analogue\u2010type":[194],"scale":[195],"would":[196],"facilitate":[197],"research,":[198],"perhaps":[200],"enhance":[201],"use":[203],"Depression":[207],"2:233\u2013240":[208],"(1994/1995).":[209],"\u00a9":[210],"1995":[211],"Wiley\u2010Liss,":[212],"Inc.":[213]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}