{"id":"https://openalex.org/W2038434669","doi":"https://doi.org/10.1097/00003246-199912001-00061","title":"INCREASED ADENOSINE CONCENTRATION IN CEREBROSPINAL FLUID AFTER SEVERE TRAUMATIC BRAIN INJURY IN INFANTS AND CHILDREN: ASSOCIATION WITH SEVERITY OF INJURY","display_name":"INCREASED ADENOSINE CONCENTRATION IN CEREBROSPINAL FLUID AFTER SEVERE TRAUMATIC BRAIN INJURY IN INFANTS AND CHILDREN: ASSOCIATION WITH SEVERITY OF INJURY","publication_year":1999,"publication_date":"1999-12-01","ids":{"openalex":"https://openalex.org/W2038434669","doi":"https://doi.org/10.1097/00003246-199912001-00061","mag":"2038434669"},"language":"en","primary_location":{"id":"doi:10.1097/00003246-199912001-00061","doi":"https://doi.org/10.1097/00003246-199912001-00061","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00003246-199912001-00061","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022651094","display_name":"Courtney Robertson","orcid":"https://orcid.org/0000-0002-2561-3837","observed_orcids":["https://orcid.org/0000-0002-2561-3837"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Courtney L Robertson","raw_affiliation_strings":["Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102750155","display_name":"Michael J. Bell","orcid":"https://orcid.org/0000-0003-0681-901X","observed_orcids":["https://orcid.org/0000-0003-0681-901X"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael J Bell","raw_affiliation_strings":["Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080778824","display_name":"Patrick Michael Kochanek","orcid":"https://orcid.org/0000-0002-2627-913X","observed_orcids":["https://orcid.org/0000-0002-2627-913X"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick M Kochanek","raw_affiliation_strings":["Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112527488","display_name":"P. David Adelson","orcid":"https://orcid.org/0000-0001-9562-143X","observed_orcids":["https://orcid.org/0000-0001-9562-143X"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P David Adelson","raw_affiliation_strings":["Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)","Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)","institution_ids":[]},{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022417440","display_name":"Randall A. Ruppel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Randall Ruppel","raw_affiliation_strings":["Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062088708","display_name":"Stephen R. Wisniewski","orcid":"https://orcid.org/0000-0002-3877-9860","observed_orcids":["https://orcid.org/0000-0002-3877-9860"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen Wisniewski","raw_affiliation_strings":["Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110565352","display_name":"Zaichuan Mi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zaichuan Mi","raw_affiliation_strings":["Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026207084","display_name":"Keri L. Janesko","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Keri L Janesko","raw_affiliation_strings":["Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058521832","display_name":"Robert S. B. Clark","orcid":"https://orcid.org/0000-0002-0806-8005","observed_orcids":["https://orcid.org/0000-0002-0806-8005"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert S B Clark","raw_affiliation_strings":["Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005780035","display_name":"Edwin Kerry Jackson","orcid":"https://orcid.org/0000-0002-8101-6009","observed_orcids":["https://orcid.org/0000-0002-8101-6009"]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edwin K Jackson","raw_affiliation_strings":["Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, Pittsburgh, PA (Jackson)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Univ Pittsburgh and Safar Ctr for Resuscitation Res, Pittsburgh, PA (Clark)","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Safar Ctr for Resuscitation Res, PIttsburgh, PA (Robertson, Bell, Kochanek, Adelson, Ruppel, Wisniewski, Mi, Janesko)","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I170201317"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"27","issue":"Supplement","first_page":"A38","last_page":"A38"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10416","display_name":"Traumatic Brain Injury Research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11406","display_name":"Cerebrospinal fluid and hydrocephalus","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adenosine","display_name":"adenosine","score":0.9890000224113464},{"id":"https://openalex.org/keywords/cerebrospinal-fluid","display_name":"cerebrospinal fluid","score":0.9980000257492065},{"id":"https://openalex.org/keywords/traumatic-brain-injury","display_name":"traumatic brain injury","score":0.9800000190734863},{"id":"https://openalex.org/keywords/infants","display_name":"infants","score":0.5529999732971191},{"id":"https://openalex.org/keywords/children","display_name":"children","score":0.9909999966621399},{"id":"https://openalex.org/keywords/injury-severity","display_name":"injury severity","score":0.9779999852180481},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.746999979019165}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9545459747314453},{"id":"https://openalex.org/C2781017439","wikidata":"https://www.wikidata.org/wiki/Q1995526","display_name":"Traumatic brain injury","level":2,"score":0.7876247763633728},{"id":"https://openalex.org/C2779651940","wikidata":"https://www.wikidata.org/wiki/Q54196","display_name":"Cerebrospinal fluid","level":2,"score":0.6734968423843384},{"id":"https://openalex.org/C2776991684","wikidata":"https://www.wikidata.org/wiki/Q190012","display_name":"Adenosine","level":2,"score":0.5677912831306458},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5398937463760376},{"id":"https://openalex.org/C2777975874","wikidata":"https://www.wikidata.org/wiki/Q2920572","display_name":"Head injury","level":2,"score":0.4289226233959198},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2977135181427002},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.15177804231643677},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.07829168438911438}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1097/00003246-199912001-00061","doi":"https://doi.org/10.1097/00003246-199912001-00061","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00003246-199912001-00061","pdf_url":null,"source":{"id":"https://openalex.org/S108732581","display_name":"Critical Care Medicine","issn_l":"0090-3493","issn":["0090-3493","1530-0293"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Critical Care Medicine","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9922999739646912}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4234743443","https://openalex.org/W1984266468","https://openalex.org/W2570061177","https://openalex.org/W2043598706","https://openalex.org/W2052546076","https://openalex.org/W2066983499","https://openalex.org/W2088173758","https://openalex.org/W2011430710","https://openalex.org/W2552555660","https://openalex.org/W2060982316"],"abstract_inverted_index":{"Society":[0],"Of":[1],"Critical":[2],"Care":[3],"Medicine":[4],"29Th":[5],"Educational":[6],"And":[7],"Scientific":[8],"Symposium;":[9],"Orlando,":[10],"Florida,":[11],"Usa;":[12],"February":[13],"11-15,":[14],"2000:":[15],"Oral":[16],"Presentations":[17]},"counts_by_year":[{"year":2015,"cited_by_count":1}],"updated_date":"2026-09-24T07:57:37.273135","created_date":"2016-06-24T00:00:00"}