{"id":"https://openalex.org/W2038091108","doi":"https://doi.org/10.1097/00002093-200607001-00020","title":"Relationship of Silent Cerebral Infarctions and White Matter Hyperintensities to Cognitive Performance in the Framingham Offspring Study","display_name":"Relationship of Silent Cerebral Infarctions and White Matter Hyperintensities to Cognitive Performance in the Framingham Offspring Study","publication_year":2006,"publication_date":"2006-07-01","ids":{"openalex":"https://openalex.org/W2038091108","doi":"https://doi.org/10.1097/00002093-200607001-00020","mag":"2038091108"},"language":"en","primary_location":{"id":"doi:10.1097/00002093-200607001-00020","doi":"https://doi.org/10.1097/00002093-200607001-00020","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00002093-200607001-00020","pdf_url":null,"source":{"id":"https://openalex.org/S107889856","display_name":"Alzheimer Disease & Associated Disorders","issn_l":"0893-0341","issn":["0893-0341","1546-4156"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer Disease & Associated Disorders","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087342044","display_name":"Karrah Q. Bristow","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210164563","display_name":"Neurology, Inc","ror":"https://ror.org/05ne0gd95","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210164563"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Karrah Q. Bristow","raw_affiliation_strings":["Neurology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology","institution_ids":["https://openalex.org/I4210164563"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017168859","display_name":"Rhoda Au","orcid":"https://orcid.org/0000-0001-7742-4491","observed_orcids":["https://orcid.org/0000-0001-7742-4491"]},"institutions":[{"id":"https://openalex.org/I4210164563","display_name":"Neurology, Inc","ror":"https://ror.org/05ne0gd95","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210164563"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Rhoda Au","raw_affiliation_strings":["Neurology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology","institution_ids":["https://openalex.org/I4210164563"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008596377","display_name":"Joseph M. Massaro","orcid":"https://orcid.org/0000-0002-2682-4812","observed_orcids":["https://orcid.org/0000-0002-2682-4812"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph M. Massaro","raw_affiliation_strings":["Biostatistics, Boston University School of Medicine","Department of Mathematics and Statistics, Boston University School of Public Health, Boston, MA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biostatistics, Boston University School of Medicine","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Department of Mathematics and Statistics, Boston University School of Public Health, Boston, MA","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011863508","display_name":"Sudha S. Seshadri","orcid":"https://orcid.org/0000-0001-6135-2622","observed_orcids":["https://orcid.org/0000-0001-6135-2622"]},"institutions":[{"id":"https://openalex.org/I4210164563","display_name":"Neurology, Inc","ror":"https://ror.org/05ne0gd95","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210164563"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sudha Seshadri","raw_affiliation_strings":["Neurology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology","institution_ids":["https://openalex.org/I4210164563"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036370752","display_name":"Philip A. Wolf","orcid":"https://orcid.org/0000-0002-7752-3526","observed_orcids":["https://orcid.org/0000-0002-7752-3526"]},"institutions":[{"id":"https://openalex.org/I4210164563","display_name":"Neurology, Inc","ror":"https://ror.org/05ne0gd95","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210164563"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Philip A. Wolf","raw_affiliation_strings":["Neurology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology","institution_ids":["https://openalex.org/I4210164563"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066271194","display_name":"Margaret Kelly\u2010Hayes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210164563","display_name":"Neurology, Inc","ror":"https://ror.org/05ne0gd95","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210164563"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Margaret Kelly-Hayes","raw_affiliation_strings":["Neurology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neurology","institution_ids":["https://openalex.org/I4210164563"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5071825455","display_name":"Charles S DeCarli","orcid":"https://orcid.org/0000-0003-1914-2693","observed_orcids":["https://orcid.org/0000-0003-1914-2693"]},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles DeCarli","raw_affiliation_strings":["Department of Neurology and Center for Neuroscience, University of California, Davis, Sacramento, CA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurology and Center for Neuroscience, University of California, Davis, Sacramento, CA","institution_ids":["https://openalex.org/I84218800"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5011863508","https://openalex.org/A5017168859","https://openalex.org/A5036370752","https://openalex.org/A5066271194","https://openalex.org/A5087342044"],"corresponding_institution_ids":["https://openalex.org/I4210164563"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"20","issue":"Supplement 2","first_page":"S101","last_page":"S101"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.7583000063896179,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.7583000063896179,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13648","display_name":"Cerebrovascular and genetic disorders","score":0.2337999939918518,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14144","display_name":"Neurological Disease Mechanisms and Treatments","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/silent-cerebral-infarction","display_name":"silent cerebral infarction","score":0.9309999942779541},{"id":"https://openalex.org/keywords/white-matter-hyperintensities","display_name":"white matter hyperintensities","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cognitive-performance","display_name":"cognitive performance","score":0.996999979019165},{"id":"https://openalex.org/keywords/cognitive-decline","display_name":"cognitive decline","score":0.4099999964237213},{"id":"https://openalex.org/keywords/framingham-offspring-study","display_name":"Framingham Offspring Study","score":0.7540000081062317},{"id":"https://openalex.org/keywords/cerebral-small-vessel-disease","display_name":"cerebral small vessel disease","score":0.515999972820282},{"id":"https://openalex.org/keywords/dementia-risk","display_name":"dementia risk","score":0.49000000953674316}],"concepts":[{"id":"https://openalex.org/C146638467","wikidata":"https://www.wikidata.org/wiki/Q10529587","display_name":"Hyperintensity","level":3,"score":0.7843306660652161},{"id":"https://openalex.org/C112672928","wikidata":"https://www.wikidata.org/wiki/Q239526","display_name":"Offspring","level":3,"score":0.6839002370834351},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5696506500244141},{"id":"https://openalex.org/C2781192897","wikidata":"https://www.wikidata.org/wiki/Q822050","display_name":"White matter","level":3,"score":0.5121700763702393},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.48957929015159607},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.3790019154548645},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.3701673746109009},{"id":"https://openalex.org/C548259974","wikidata":"https://www.wikidata.org/wiki/Q569965","display_name":"Audiology","level":1,"score":0.3401463031768799},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.33185094594955444},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3143296241760254},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.12677544355392456},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.06370913982391357},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1097/00002093-200607001-00020","doi":"https://doi.org/10.1097/00002093-200607001-00020","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00002093-200607001-00020","pdf_url":null,"source":{"id":"https://openalex.org/S107889856","display_name":"Alzheimer Disease & Associated Disorders","issn_l":"0893-0341","issn":["0893-0341","1546-4156"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer Disease & Associated Disorders","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2143939285","https://openalex.org/W2010339122","https://openalex.org/W2999229806","https://openalex.org/W2471446255","https://openalex.org/W2087323177","https://openalex.org/W2885659241","https://openalex.org/W1969030071","https://openalex.org/W2060774463","https://openalex.org/W2897627408","https://openalex.org/W2592188435"],"abstract_inverted_index":{"Bristow,":[0],"Karrah":[1],"Q.*;":[2],"Au,":[3],"Rhoda*;":[4],"Massaro,":[5],"Joseph":[6],"M.\u2020":[7],"\u2021;":[8],"Seshadri,":[9],"Sudha*;":[10],"Wolf,":[11],"Philip":[12],"A.*;":[13],"Kelly-Hayes,":[14],"Margaret*;":[15],"DeCarli,":[16],"Charles\u00a7":[17],"Author":[18],"Information":[19]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}