{"id":"https://openalex.org/W2037873016","doi":"https://doi.org/10.1053/meta.2000.8602","title":"Interaction on metabolic clearance between A-type and B-type natriuretic peptides in patients with heart failure","display_name":"Interaction on metabolic clearance between A-type and B-type natriuretic peptides in patients with heart failure","publication_year":2000,"publication_date":"2000-09-01","ids":{"openalex":"https://openalex.org/W2037873016","doi":"https://doi.org/10.1053/meta.2000.8602","mag":"2037873016","pmid":"https://pubmed.ncbi.nlm.nih.gov/11016910"},"language":"en","primary_location":{"id":"doi:10.1053/meta.2000.8602","doi":"https://doi.org/10.1053/meta.2000.8602","is_oa":false,"landing_page_url":"https://doi.org/10.1053/meta.2000.8602","pdf_url":null,"source":{"id":"https://openalex.org/S119661813","display_name":"Metabolism","issn_l":"0026-0495","issn":["0026-0495","1532-8600"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolism","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110123337","display_name":"Michihiro Yoshimura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Michihiro Yoshimura","raw_affiliation_strings":["Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Japan","Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Japan","institution_ids":["https://openalex.org/I96036126"]},{"raw_affiliation_string":"Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055474625","display_name":"Yuji Mizuno","orcid":"https://orcid.org/0000-0001-9255-9693","observed_orcids":["https://orcid.org/0000-0001-9255-9693"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yuji Mizuno","raw_affiliation_strings":["From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I96036126"]},{"raw_affiliation_string":"Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012233468","display_name":"Eisaku Harada","orcid":"https://orcid.org/0000-0002-2734-5303","observed_orcids":["https://orcid.org/0000-0002-2734-5303"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Eisaku Harada","raw_affiliation_strings":["From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I96036126"]},{"raw_affiliation_string":"Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049895325","display_name":"Masafumi Nakayama","orcid":"https://orcid.org/0000-0002-4499-7522","observed_orcids":["https://orcid.org/0000-0002-4499-7522"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masafumi Nakayama","raw_affiliation_strings":["From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I96036126"]},{"raw_affiliation_string":"Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075495420","display_name":"Yukio Shimasaki","orcid":"https://orcid.org/0000-0002-8425-5830","observed_orcids":["https://orcid.org/0000-0002-8425-5830"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yukio Shimasaki","raw_affiliation_strings":["From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I96036126"]},{"raw_affiliation_string":"Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109228277","display_name":"Teruhiko Ito","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Teruhiko Ito","raw_affiliation_strings":["From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I96036126"]},{"raw_affiliation_string":"Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085879794","display_name":"Shota Nakamura","orcid":"https://orcid.org/0000-0002-1865-0867","observed_orcids":["https://orcid.org/0000-0002-1865-0867"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shota Nakamura","raw_affiliation_strings":["From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I96036126"]},{"raw_affiliation_string":"Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015115080","display_name":"Hirofumi Soejima","orcid":"https://orcid.org/0000-0002-7520-2008","observed_orcids":["https://orcid.org/0000-0002-7520-2008"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hirofumi Soejima","raw_affiliation_strings":["From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I96036126"]},{"raw_affiliation_string":"Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111739055","display_name":"Shinzo Miyamoto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinzo Miyamoto","raw_affiliation_strings":["From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I96036126"]},{"raw_affiliation_string":"Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111642283","display_name":"Keiji Takazoe","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Keiji Takazoe","raw_affiliation_strings":["From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I96036126"]},{"raw_affiliation_string":"Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113433111","display_name":"Hisao Ogawa","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hisao Ogawa","raw_affiliation_strings":["From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I96036126"]},{"raw_affiliation_string":"Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103257128","display_name":"Kiyotaka Kugiyama","orcid":"https://orcid.org/0000-0002-9138-4825","observed_orcids":["https://orcid.org/0000-0002-9138-4825"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kiyotaka Kugiyama","raw_affiliation_strings":["From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I96036126"]},{"raw_affiliation_string":"Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025174992","display_name":"Yoshihiko Saito","orcid":"https://orcid.org/0000-0003-1643-4797","observed_orcids":["https://orcid.org/0000-0003-1643-4797"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yoshihiko Saito","raw_affiliation_strings":["From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I96036126"]},{"raw_affiliation_string":"Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5105832217","display_name":"Kazuwa Nakao","orcid":"https://orcid.org/0000-0003-3483-4196","observed_orcids":["https://orcid.org/0000-0003-3483-4196"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kazuwa Nakao","raw_affiliation_strings":["From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I96036126"]},{"raw_affiliation_string":"Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto","institution_ids":["https://openalex.org/I96036126"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091430660","display_name":"Hirofumi Yasue","orcid":"https://orcid.org/0000-0002-9952-9638","observed_orcids":["https://orcid.org/0000-0002-9952-9638"]},"institutions":[{"id":"https://openalex.org/I22299242","display_name":"Kyoto University","ror":"https://ror.org/02kpeqv85","country_code":"JP","type":"education","lineage":["https://openalex.org/I22299242"]},{"id":"https://openalex.org/I96036126","display_name":"Kumamoto University","ror":"https://ror.org/02cgss904","country_code":"JP","type":"education","lineage":["https://openalex.org/I96036126"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hirofumi Yasue","raw_affiliation_strings":["From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto; and Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242","https://openalex.org/I96036126"]},{"raw_affiliation_string":"Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Kyoto, Japan","institution_ids":["https://openalex.org/I22299242"]},{"raw_affiliation_string":"From the Department of Cardiovascular Medicine, Kumamoto University School of Medicine, Kumamoto","institution_ids":["https://openalex.org/I96036126"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5340,"currency":"USD","value_usd":5340},"apc_paid":null,"fwci":0.968,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.783274,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"49","issue":"9","first_page":"1228","last_page":"1233"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10198","display_name":"Heart Failure Treatment and Management","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14486","display_name":"Cardiovascular, Neuropeptides, and Oxidative Stress Research","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/atrial-natriuretic-peptide","display_name":"atrial natriuretic peptide","score":0.9229999780654907},{"id":"https://openalex.org/keywords/brain-natriuretic-peptide","display_name":"brain natriuretic peptide","score":1.0},{"id":"https://openalex.org/keywords/heart-failure","display_name":"heart failure","score":0.9269999861717224},{"id":"https://openalex.org/keywords/coronary-sinus","display_name":"coronary sinus","score":0.9100000262260437},{"id":"https://openalex.org/keywords/aortic-root","display_name":"aortic root","score":0.968999981880188},{"id":"https://openalex.org/keywords/pulmonary-circulation","display_name":"pulmonary circulation","score":0.7080000042915344},{"id":"https://openalex.org/keywords/natriuretic-peptide-clearance-receptor","display_name":"natriuretic peptide clearance receptor","score":0.9169999957084656},{"id":"https://openalex.org/keywords/neutral-endopeptidase-24-11","display_name":"neutral endopeptidase 24.11","score":0.9869999885559082}],"concepts":[{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.8028648495674133},{"id":"https://openalex.org/C2778259205","wikidata":"https://www.wikidata.org/wiki/Q629460","display_name":"Coronary sinus","level":2,"score":0.7621611952781677},{"id":"https://openalex.org/C2778069365","wikidata":"https://www.wikidata.org/wiki/Q78185357","display_name":"Atrial natriuretic peptide","level":2,"score":0.7127043604850769},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.6878061294555664},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6515157222747803},{"id":"https://openalex.org/C2775915353","wikidata":"https://www.wikidata.org/wiki/Q1571529","display_name":"Natriuretic peptide","level":3,"score":0.6502532362937927},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6430857181549072},{"id":"https://openalex.org/C2993369777","wikidata":"https://www.wikidata.org/wiki/Q2349469","display_name":"Aortic root","level":3,"score":0.5780723094940186},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.534392774105072},{"id":"https://openalex.org/C2779980429","wikidata":"https://www.wikidata.org/wiki/Q101004","display_name":"Aorta","level":2,"score":0.2610975503921509}],"mesh":[{"descriptor_ui":"D001011","descriptor_name":"Aorta","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002303","descriptor_name":"Cardiac Output, Low","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D002311","descriptor_name":"Cardiomyopathy, Dilated","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006328","descriptor_name":"Cardiac Catheterization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008657","descriptor_name":"Metabolic Clearance Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009203","descriptor_name":"Myocardial Infarction","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009320","descriptor_name":"Atrial Natriuretic Factor","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D011652","descriptor_name":"Pulmonary Circulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016014","descriptor_name":"Linear Models","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020097","descriptor_name":"Natriuretic Peptide, Brain","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1053/meta.2000.8602","doi":"https://doi.org/10.1053/meta.2000.8602","is_oa":false,"landing_page_url":"https://doi.org/10.1053/meta.2000.8602","pdf_url":null,"source":{"id":"https://openalex.org/S119661813","display_name":"Metabolism","issn_l":"0026-0495","issn":["0026-0495","1532-8600"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolism","raw_type":"journal-article"},{"id":"pmid:11016910","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/11016910","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolism: clinical and experimental","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":38,"referenced_works":["https://openalex.org/W202078600","https://openalex.org/W1527607980","https://openalex.org/W1545907965","https://openalex.org/W1881125874","https://openalex.org/W1912249044","https://openalex.org/W1965293430","https://openalex.org/W1968130104","https://openalex.org/W1973521756","https://openalex.org/W1975728622","https://openalex.org/W1979659033","https://openalex.org/W1981438457","https://openalex.org/W1999786342","https://openalex.org/W2017554373","https://openalex.org/W2024667090","https://openalex.org/W2041179424","https://openalex.org/W2046971992","https://openalex.org/W2051743630","https://openalex.org/W2053561973","https://openalex.org/W2054649519","https://openalex.org/W2056851052","https://openalex.org/W2065142882","https://openalex.org/W2071166583","https://openalex.org/W2076734878","https://openalex.org/W2085065650","https://openalex.org/W2085160647","https://openalex.org/W2094948309","https://openalex.org/W2099601233","https://openalex.org/W2101692759","https://openalex.org/W2105157791","https://openalex.org/W2111085659","https://openalex.org/W2121815042","https://openalex.org/W2152681817","https://openalex.org/W2168090194","https://openalex.org/W2178658250","https://openalex.org/W2181671034","https://openalex.org/W2197404395","https://openalex.org/W2260795855","https://openalex.org/W2407415995"],"related_works":["https://openalex.org/W2228246024","https://openalex.org/W2024627015","https://openalex.org/W1979659033","https://openalex.org/W2017554373","https://openalex.org/W1979427398","https://openalex.org/W2277969919","https://openalex.org/W7099273771","https://openalex.org/W2035681674","https://openalex.org/W2101692759","https://openalex.org/W2155428322"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}