{"id":"https://openalex.org/W2037726647","doi":"https://doi.org/10.1038/srep08791","title":"New Cyt-like \u03b4-endotoxins from Dickeya dadantii: structure and aphicidal activity","display_name":"New Cyt-like \u03b4-endotoxins from Dickeya dadantii: structure and aphicidal activity","publication_year":2015,"publication_date":"2015-03-05","ids":{"openalex":"https://openalex.org/W2037726647","doi":"https://doi.org/10.1038/srep08791","mag":"2037726647","pmid":"https://pubmed.ncbi.nlm.nih.gov/25740111","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/5390079"},"language":"en","primary_location":{"id":"doi:10.1038/srep08791","doi":"https://doi.org/10.1038/srep08791","is_oa":true,"landing_page_url":"https://doi.org/10.1038/srep08791","pdf_url":"https://www.nature.com/articles/srep08791.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2037726647"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/srep08791.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072010865","display_name":"Karine Loth","orcid":"https://orcid.org/0000-0001-7058-8661","observed_orcids":["https://orcid.org/0000-0001-7058-8661"]},"institutions":[{"id":"https://openalex.org/I12449238","display_name":"Universit\u00e9 d'Orl\u00e9ans","ror":"https://ror.org/014zrew76","country_code":"FR","type":"education","lineage":["https://openalex.org/I12449238"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210118525","display_name":"Centre de Biophysique Mol\u00e9culaire","ror":"https://ror.org/02dpqcy73","country_code":"FR","type":"facility","lineage":["https://openalex.org/I110017253","https://openalex.org/I12449238","https://openalex.org/I1294671590","https://openalex.org/I4210096427","https://openalex.org/I4210118525","https://openalex.org/I4210128300"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Karine Loth","raw_affiliation_strings":["Centre de Biophysique Mol\u00e9culaire, CNRS UPR 4301, Universit\u00e9 d'Orl\u00e9ans, Orl\u00e9ans, F-45071, France","Centre de Biophysique Mol\u00e9culaire, CNRS-UPR 4301, Universit\u00e9 d'Orl\u00e9ans, Orl\u00e9ans, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Biophysique Mol\u00e9culaire, CNRS UPR 4301, Universit\u00e9 d'Orl\u00e9ans, Orl\u00e9ans, F-45071, France","institution_ids":["https://openalex.org/I12449238","https://openalex.org/I1294671590","https://openalex.org/I4210118525"]},{"raw_affiliation_string":"Centre de Biophysique Mol\u00e9culaire, CNRS-UPR 4301, Universit\u00e9 d'Orl\u00e9ans, Orl\u00e9ans, France","institution_ids":["https://openalex.org/I12449238","https://openalex.org/I1294671590","https://openalex.org/I4210118525"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033469741","display_name":"Denis Costechareyre","orcid":"https://orcid.org/0000-0002-9258-7421","observed_orcids":["https://orcid.org/0000-0002-9258-7421"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I203339264","display_name":"Universit\u00e9 de Lyon","ror":"https://ror.org/01rk35k63","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264"]},{"id":"https://openalex.org/I4210129159","display_name":"Laboratoire de Microbiologie, Adaptation et Pathog\u00e9nie","ror":"https://ror.org/03p3f6k20","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210096427","https://openalex.org/I4210129159","https://openalex.org/I4210166400","https://openalex.org/I48430043","https://openalex.org/I67348948"]},{"id":"https://openalex.org/I48430043","display_name":"Institut National des Sciences Appliqu\u00e9es de Lyon","ror":"https://ror.org/050jn9y42","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I48430043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Denis Costechareyre","raw_affiliation_strings":["1] INSA-Lyon, Villeurbanne F-69621, France [2] CNRS, UMR5240 MAP, Microbiologie Adaptation et Pathog\u00e9nie, F-69622, France [3] Universit\u00e9 Claude Bernard Lyon 1, F-69622, France [4] Universit\u00e9 de Lyon, F-69000 Lyon, France","INSA-Lyon, Villeurbanne, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1] INSA-Lyon, Villeurbanne F-69621, France [2] CNRS, UMR5240 MAP, Microbiologie Adaptation et Pathog\u00e9nie, F-69622, France [3] Universit\u00e9 Claude Bernard Lyon 1, F-69622, France [4] Universit\u00e9 de Lyon, F-69000 Lyon, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210129159","https://openalex.org/I48430043"]},{"raw_affiliation_string":"INSA-Lyon, Villeurbanne, France","institution_ids":["https://openalex.org/I48430043"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037411679","display_name":"G\u00e9raldine Effantin","orcid":"https://orcid.org/0000-0002-7296-0831","observed_orcids":["https://orcid.org/0000-0002-7296-0831"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I203339264","display_name":"Universit\u00e9 de Lyon","ror":"https://ror.org/01rk35k63","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264"]},{"id":"https://openalex.org/I4210129159","display_name":"Laboratoire de Microbiologie, Adaptation et Pathog\u00e9nie","ror":"https://ror.org/03p3f6k20","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210096427","https://openalex.org/I4210129159","https://openalex.org/I4210166400","https://openalex.org/I48430043","https://openalex.org/I67348948"]},{"id":"https://openalex.org/I48430043","display_name":"Institut National des Sciences Appliqu\u00e9es de Lyon","ror":"https://ror.org/050jn9y42","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I48430043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"G\u00e9raldine Effantin","raw_affiliation_strings":["1] INSA-Lyon, Villeurbanne F-69621, France [2] CNRS, UMR5240 MAP, Microbiologie Adaptation et Pathog\u00e9nie, F-69622, France [3] Universit\u00e9 Claude Bernard Lyon 1, F-69622, France [4] Universit\u00e9 de Lyon, F-69000 Lyon, France","INSA-Lyon, Villeurbanne, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1] INSA-Lyon, Villeurbanne F-69621, France [2] CNRS, UMR5240 MAP, Microbiologie Adaptation et Pathog\u00e9nie, F-69622, France [3] Universit\u00e9 Claude Bernard Lyon 1, F-69622, France [4] Universit\u00e9 de Lyon, F-69000 Lyon, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210129159","https://openalex.org/I48430043"]},{"raw_affiliation_string":"INSA-Lyon, Villeurbanne, France","institution_ids":["https://openalex.org/I48430043"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079878245","display_name":"Yvan Rahb\u00e9","orcid":"https://orcid.org/0000-0002-0074-4443","observed_orcids":["https://orcid.org/0000-0002-0074-4443"]},"institutions":[{"id":"https://openalex.org/I203339264","display_name":"Universit\u00e9 de Lyon","ror":"https://ror.org/01rk35k63","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210129169","display_name":"Biologie Fonctionnelle Insectes et Interactions","ror":"https://ror.org/03d1jma17","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210129169","https://openalex.org/I48430043"]},{"id":"https://openalex.org/I48430043","display_name":"Institut National des Sciences Appliqu\u00e9es de Lyon","ror":"https://ror.org/050jn9y42","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I48430043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Yvan Rahb\u00e9","raw_affiliation_strings":["1] INSA-Lyon, Villeurbanne F-69621, France [2] Universit\u00e9 de Lyon, F-69000 Lyon, France [3] INRA, UMR203 BF2I, Biologie Fonctionnelle Insecte et Interaction, F-69621, France","INRA, UMR203 BF2I, Biologie Fonctionnelle Insecte et Interaction, France","INSA-Lyon, Villeurbanne, France","Universit\u00e9 de Lyon, Lyon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1] INSA-Lyon, Villeurbanne F-69621, France [2] Universit\u00e9 de Lyon, F-69000 Lyon, France [3] INRA, UMR203 BF2I, Biologie Fonctionnelle Insecte et Interaction, F-69621, France","institution_ids":["https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210129169","https://openalex.org/I48430043"]},{"raw_affiliation_string":"INRA, UMR203 BF2I, Biologie Fonctionnelle Insecte et Interaction, France","institution_ids":["https://openalex.org/I4210088668","https://openalex.org/I4210129169"]},{"raw_affiliation_string":"INSA-Lyon, Villeurbanne, France","institution_ids":["https://openalex.org/I48430043"]},{"raw_affiliation_string":"Universit\u00e9 de Lyon, Lyon, France","institution_ids":["https://openalex.org/I203339264"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052482256","display_name":"Guy Condemine","orcid":"https://orcid.org/0000-0002-3256-3815","observed_orcids":["https://orcid.org/0000-0002-3256-3815"]},"institutions":[{"id":"https://openalex.org/I100532134","display_name":"Lyon 1 Universit\u00e9","ror":"https://ror.org/029brtt94","country_code":"FR","type":"education","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I203339264","display_name":"Universit\u00e9 de Lyon","ror":"https://ror.org/01rk35k63","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264"]},{"id":"https://openalex.org/I4210129159","display_name":"Laboratoire de Microbiologie, Adaptation et Pathog\u00e9nie","ror":"https://ror.org/03p3f6k20","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210096427","https://openalex.org/I4210129159","https://openalex.org/I4210166400","https://openalex.org/I48430043","https://openalex.org/I67348948"]},{"id":"https://openalex.org/I48430043","display_name":"Institut National des Sciences Appliqu\u00e9es de Lyon","ror":"https://ror.org/050jn9y42","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I48430043"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Guy Condemine","raw_affiliation_strings":["1] INSA-Lyon, Villeurbanne F-69621, France [2] CNRS, UMR5240 MAP, Microbiologie Adaptation et Pathog\u00e9nie, F-69622, France [3] Universit\u00e9 Claude Bernard Lyon 1, F-69622, France [4] Universit\u00e9 de Lyon, F-69000 Lyon, France","INSA-Lyon, Villeurbanne, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1] INSA-Lyon, Villeurbanne F-69621, France [2] CNRS, UMR5240 MAP, Microbiologie Adaptation et Pathog\u00e9nie, F-69622, France [3] Universit\u00e9 Claude Bernard Lyon 1, F-69622, France [4] Universit\u00e9 de Lyon, F-69000 Lyon, France","institution_ids":["https://openalex.org/I100532134","https://openalex.org/I1294671590","https://openalex.org/I203339264","https://openalex.org/I4210129159","https://openalex.org/I48430043"]},{"raw_affiliation_string":"INSA-Lyon, Villeurbanne, France","institution_ids":["https://openalex.org/I48430043"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072392864","display_name":"C\u00e9line Landon","orcid":"https://orcid.org/0000-0002-0248-1990","observed_orcids":["https://orcid.org/0000-0002-0248-1990"]},"institutions":[{"id":"https://openalex.org/I12449238","display_name":"Universit\u00e9 d'Orl\u00e9ans","ror":"https://ror.org/014zrew76","country_code":"FR","type":"education","lineage":["https://openalex.org/I12449238"]},{"id":"https://openalex.org/I1294671590","display_name":"Centre National de la Recherche Scientifique","ror":"https://ror.org/02feahw73","country_code":"FR","type":"government","lineage":["https://openalex.org/I1294671590"]},{"id":"https://openalex.org/I4210118525","display_name":"Centre de Biophysique Mol\u00e9culaire","ror":"https://ror.org/02dpqcy73","country_code":"FR","type":"facility","lineage":["https://openalex.org/I110017253","https://openalex.org/I12449238","https://openalex.org/I1294671590","https://openalex.org/I4210096427","https://openalex.org/I4210118525","https://openalex.org/I4210128300"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"C\u00e9line Landon","raw_affiliation_strings":["Centre de Biophysique Mol\u00e9culaire, CNRS UPR 4301, Universit\u00e9 d'Orl\u00e9ans, Orl\u00e9ans, F-45071, France","Centre de Biophysique Mol\u00e9culaire, CNRS-UPR 4301, Universit\u00e9 d'Orl\u00e9ans, Orl\u00e9ans, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre de Biophysique Mol\u00e9culaire, CNRS UPR 4301, Universit\u00e9 d'Orl\u00e9ans, Orl\u00e9ans, F-45071, France","institution_ids":["https://openalex.org/I12449238","https://openalex.org/I1294671590","https://openalex.org/I4210118525"]},{"raw_affiliation_string":"Centre de Biophysique Mol\u00e9culaire, CNRS-UPR 4301, Universit\u00e9 d'Orl\u00e9ans, Orl\u00e9ans, France","institution_ids":["https://openalex.org/I12449238","https://openalex.org/I1294671590","https://openalex.org/I4210118525"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055764058","display_name":"Pedro Da Silva","orcid":"https://orcid.org/0000-0002-9275-8956","observed_orcids":["https://orcid.org/0000-0002-9275-8956","https://orcid.org/0000-0002-9869-5271"]},"institutions":[{"id":"https://openalex.org/I203339264","display_name":"Universit\u00e9 de Lyon","ror":"https://ror.org/01rk35k63","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210129169","display_name":"Biologie Fonctionnelle Insectes et Interactions","ror":"https://ror.org/03d1jma17","country_code":"FR","type":"facility","lineage":["https://openalex.org/I100532134","https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210129169","https://openalex.org/I48430043"]},{"id":"https://openalex.org/I48430043","display_name":"Institut National des Sciences Appliqu\u00e9es de Lyon","ror":"https://ror.org/050jn9y42","country_code":"FR","type":"education","lineage":["https://openalex.org/I203339264","https://openalex.org/I48430043"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Pedro da Silva","raw_affiliation_strings":["1] INSA-Lyon, Villeurbanne F-69621, France [2] Universit\u00e9 de Lyon, F-69000 Lyon, France [3] INRA, UMR203 BF2I, Biologie Fonctionnelle Insecte et Interaction, F-69621, France","INRA, UMR203 BF2I, Biologie Fonctionnelle Insecte et Interaction, France","INSA-Lyon, Villeurbanne, France","Universit\u00e9 de Lyon, Lyon, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1] INSA-Lyon, Villeurbanne F-69621, France [2] Universit\u00e9 de Lyon, F-69000 Lyon, France [3] INRA, UMR203 BF2I, Biologie Fonctionnelle Insecte et Interaction, F-69621, France","institution_ids":["https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210129169","https://openalex.org/I48430043"]},{"raw_affiliation_string":"INRA, UMR203 BF2I, Biologie Fonctionnelle Insecte et Interaction, France","institution_ids":["https://openalex.org/I4210088668","https://openalex.org/I4210129169"]},{"raw_affiliation_string":"INSA-Lyon, Villeurbanne, France","institution_ids":["https://openalex.org/I48430043"]},{"raw_affiliation_string":"Universit\u00e9 de Lyon, Lyon, France","institution_ids":["https://openalex.org/I203339264"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5055764058"],"corresponding_institution_ids":["https://openalex.org/I203339264","https://openalex.org/I4210088668","https://openalex.org/I4210129169","https://openalex.org/I48430043"],"apc_list":{"value":2690,"currency":"USD","value_usd":2690},"apc_paid":{"value":2690,"currency":"USD","value_usd":2690},"fwci":0.3176,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.49567638,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"5","issue":"1","first_page":"8791","last_page":"8791"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11075","display_name":"Insect Resistance and Genetics","score":0.8115000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11075","display_name":"Insect Resistance and Genetics","score":0.8115000128746033,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11436","display_name":"Entomopathogenic Microorganisms in Pest Control","score":0.1437000036239624,"subfield":{"id":"https://openalex.org/subfields/1109","display_name":"Insect Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12477","display_name":"Toxin Mechanisms and Immunotoxins","score":0.003700000001117587,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dickeya-dadantii","display_name":"Dickeya dadantii","score":0.9950000047683716},{"id":"https://openalex.org/keywords/cytochrome-b","display_name":"cytochrome b","score":1.0},{"id":"https://openalex.org/keywords/pea-aphid","display_name":"Acyrthosiphon pisum","score":0.8690000176429749},{"id":"https://openalex.org/keywords/aphidicidal-activity","display_name":"aphidicidal activity","score":0.8399999737739563},{"id":"https://openalex.org/keywords/biopesticides","display_name":"biopesticides","score":0.8019999861717224},{"id":"https://openalex.org/keywords/lipid-binding-pocket","display_name":"lipid-binding pocket","score":0.9549999833106995},{"id":"https://openalex.org/keywords/toxin-structure-function","display_name":"toxin structure-function","score":0.6759999990463257},{"id":"https://openalex.org/keywords/phylogenetic-analysis","display_name":"phylogenetic analysis","score":0.675000011920929},{"id":"https://openalex.org/keywords/protein-backbone-dynamics","display_name":"backbone dynamics","score":0.5389999747276306},{"id":"https://openalex.org/keywords/plant-pathogenic-bacteria","display_name":"plant pathogenic bacteria","score":0.7929999828338623}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6372918486595154},{"id":"https://openalex.org/C193252679","wikidata":"https://www.wikidata.org/wiki/Q242125","display_name":"Phylogenetic tree","level":3,"score":0.5151968598365784},{"id":"https://openalex.org/C171897839","wikidata":"https://www.wikidata.org/wiki/Q417841","display_name":"Protein family","level":3,"score":0.47347819805145264},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.46388986706733704},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4379030764102936},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.43494313955307007},{"id":"https://openalex.org/C2779035793","wikidata":"https://www.wikidata.org/wiki/Q310467","display_name":"Bacillus thuringiensis","level":3,"score":0.4168863594532013},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3305630087852478},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.3258410096168518}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001426","descriptor_name":"Bacterial Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004731","descriptor_name":"Endotoxins","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D004731","descriptor_name":"Endotoxins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004731","descriptor_name":"Endotoxins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D004731","descriptor_name":"Endotoxins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004731","descriptor_name":"Endotoxins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D004755","descriptor_name":"Enterobacteriaceae","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D004755","descriptor_name":"Enterobacteriaceae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005810","descriptor_name":"Multigene Family","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010802","descriptor_name":"Phylogeny","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012996","descriptor_name":"Solutions","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019906","descriptor_name":"Nuclear Magnetic Resonance, Biomolecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1038/srep08791","doi":"https://doi.org/10.1038/srep08791","is_oa":true,"landing_page_url":"https://doi.org/10.1038/srep08791","pdf_url":"https://www.nature.com/articles/srep08791.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"pmid:25740111","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25740111","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:5390079","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC5390079/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmh:oai:HAL:hal-01124447v1","doi":null,"is_oa":true,"landing_page_url":"https://hal.science/hal-01124447","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4405252976","host_organization_name":"Centre pour la Communication Scientifique Directe","host_organization_lineage":["https://openalex.org/I4405252976"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, 2015, 5, pp.8791. ⟨10.1038/srep08791⟩","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1038/srep08791","doi":"https://doi.org/10.1038/srep08791","is_oa":true,"landing_page_url":"https://doi.org/10.1038/srep08791","pdf_url":"https://www.nature.com/articles/srep08791.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3891162766","display_name":"Symbiosis, digestion and reproduction as Aphid physiological processes to identify new targets for insecticides","funder_award_id":"ANR-07-GPLA-0002","funder_id":"https://openalex.org/F4320320883","funder_display_name":"Agence Nationale de la Recherche"}],"funders":[{"id":"https://openalex.org/F4320320883","display_name":"Agence Nationale de la Recherche","ror":"https://ror.org/00rbzpz17"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2037726647.pdf","grobid_xml":"https://content.openalex.org/works/W2037726647.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W1505992035","https://openalex.org/W1895099583","https://openalex.org/W1962494205","https://openalex.org/W1964093586","https://openalex.org/W1965922758","https://openalex.org/W1992299051","https://openalex.org/W1999676950","https://openalex.org/W2003175728","https://openalex.org/W2003433647","https://openalex.org/W2007557015","https://openalex.org/W2019241328","https://openalex.org/W2021496016","https://openalex.org/W2023015092","https://openalex.org/W2033462690","https://openalex.org/W2053284518","https://openalex.org/W2054687889","https://openalex.org/W2055604868","https://openalex.org/W2063227014","https://openalex.org/W2066092033","https://openalex.org/W2070534813","https://openalex.org/W2070537402","https://openalex.org/W2079974886","https://openalex.org/W2082290635","https://openalex.org/W2086862822","https://openalex.org/W2092857082","https://openalex.org/W2093961064","https://openalex.org/W2105212952","https://openalex.org/W2105332890","https://openalex.org/W2109939279","https://openalex.org/W2111211467","https://openalex.org/W2120772351","https://openalex.org/W2127322768","https://openalex.org/W2135338948","https://openalex.org/W2135370889","https://openalex.org/W2136721027","https://openalex.org/W2138000592","https://openalex.org/W2141130757","https://openalex.org/W2142051212","https://openalex.org/W2145980235","https://openalex.org/W2149160071","https://openalex.org/W2152034625","https://openalex.org/W2156980476","https://openalex.org/W2161729108","https://openalex.org/W2169707043","https://openalex.org/W2169821755","https://openalex.org/W2171314806"],"related_works":["https://openalex.org/W2066768199","https://openalex.org/W2941553659","https://openalex.org/W2054687889","https://openalex.org/W2062774160","https://openalex.org/W1987893986","https://openalex.org/W2158799427","https://openalex.org/W1962494205","https://openalex.org/W1974684988","https://openalex.org/W3211887859","https://openalex.org/W1964093586"],"abstract_inverted_index":{"In":[0],"the":[1,27,51,54,71,83,101,129,149,154,162,167,177],"track":[2],"of":[3,53,61,70,74,87,104,131,148,156,164,166,182],"new":[4],"biopesticides,":[5],"four":[6],"genes":[7],"namely":[8],"cytA,":[9],"cytB,":[10],"cytC":[11],"and":[12,46,64,106,179],"cytD":[13],"encoding":[14],"proteins":[15],"homologous":[16],"to":[17,50,189],"Bacillus":[18],"thuringiensis":[19],"(Bt)":[20],"Cyt":[21,75,185],"toxins":[22,76],"have":[23,112],"been":[24,113,142],"identified":[25],"in":[26,59,78,92,110,137,145],"plant":[28],"pathogenic":[29],"bacteria":[30],"Dickeya":[31],"dadantii":[32,43,184],"genome.":[33],"Here":[34],"we":[35],"show":[36],"that":[37,82],"three":[38],"Cyt-like":[39],"\u03b4-endotoxins":[40],"from":[41],"D.":[42,183],"(CytA,":[44],"CytB":[45],"CytC)":[47],"are":[48],"toxic":[49],"pathogen":[52],"pea":[55],"aphid":[56],"Acyrthosiphon":[57],"pisum":[58],"terms":[60],"both":[62],"mortality":[63],"growth":[65],"rate.":[66],"The":[67],"phylogenetic":[68],"analysis":[69],"comprehensive":[72],"set":[73],"available":[77],"genomic":[79],"databases":[80],"shows":[81],"whole":[84,168],"family":[85],"is":[86],"limited":[88],"taxonomic":[89],"occurrence,":[90],"though":[91],"quite":[93],"diverse":[94],"microbial":[95],"taxa.":[96],"From":[97],"a":[98,119,125,132],"structure-function":[99],"perspective":[100],"3D":[102],"structure":[103],"CytC":[105,117,138],"its":[107],"backbone":[108],"dynamics":[109],"solution":[111],"determined":[114],"by":[115],"NMR.":[116],"adopts":[118],"cytolysin":[120],"fold,":[121],"structurally":[122],"classified":[123],"as":[124],"Cyt2-like":[126],"protein.":[127],"Moreover,":[128],"identification":[130],"putative":[133],"lipid":[134,158],"binding":[135,159],"pocket":[136],"structure,":[139],"which":[140,187],"has":[141],"probably":[143],"maintained":[144],"most":[146],"members":[147],"Cyt-toxin":[150],"family,":[151],"could":[152],"support":[153],"importance":[155],"this":[157],"cavity":[160],"for":[161,193],"mechanism":[163],"action":[165],"family.":[169],"This":[170],"integrative":[171],"approach":[172],"provided":[173],"significant":[174],"insights":[175],"into":[176],"evolutionary":[178],"functional":[180],"history":[181],"toxins,":[186],"appears":[188],"be":[190],"interesting":[191],"leads":[192],"biopesticides.":[194]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}