{"id":"https://openalex.org/W2037558601","doi":"https://doi.org/10.1152/ajpregu.00690.2007","title":"Zebrafish ae2.2 encodes a second slc4a2 anion exchanger","display_name":"Zebrafish ae2.2 encodes a second slc4a2 anion exchanger","publication_year":2007,"publication_date":"2007-11-28","ids":{"openalex":"https://openalex.org/W2037558601","doi":"https://doi.org/10.1152/ajpregu.00690.2007","mag":"2037558601","pmid":"https://pubmed.ncbi.nlm.nih.gov/18046018"},"language":"en","primary_location":{"id":"doi:10.1152/ajpregu.00690.2007","doi":"https://doi.org/10.1152/ajpregu.00690.2007","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpregu.00690.2007","pdf_url":null,"source":{"id":"https://openalex.org/S59702976","display_name":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","issn_l":"0363-6119","issn":["0363-6119","1522-1490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5076965086","display_name":"Boris E. Shmukler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Boris E. Shmukler","raw_affiliation_strings":["Molecular and Vascular Medicine and Renal Units, Beth Israel Deaconess Medical Center E/RW763, 330 Brookline Ave., Boston, MA 02215, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular and Vascular Medicine and Renal Units, Beth Israel Deaconess Medical Center E/RW763, 330 Brookline Ave., Boston, MA 02215, USA","institution_ids":["https://openalex.org/I1316535847"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Jeffrey S. Clark","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jeffrey S. Clark","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ann Hsu","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ann Hsu","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112190673","display_name":"David H. Vandorpe","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David H. Vandorpe","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Andrew K. Stewart","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew K. Stewart","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078927052","display_name":"Christine E. Kurschat","orcid":"https://orcid.org/0000-0002-3646-9471","observed_orcids":["https://orcid.org/0000-0002-3646-9471"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Christine E. Kurschat","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050853149","display_name":"Seong\u2010Kyu Choe","orcid":"https://orcid.org/0000-0002-2102-973X","observed_orcids":["https://orcid.org/0000-0002-2102-973X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Seong-Kyu Choe","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101881010","display_name":"Yi Zhou","orcid":"https://orcid.org/0000-0003-0935-1635","observed_orcids":["https://orcid.org/0000-0003-0935-1635"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yi Zhou","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061571753","display_name":"Julio D. Amigo","orcid":"https://orcid.org/0000-0001-8718-2676","observed_orcids":["https://orcid.org/0000-0001-8718-2676"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Julio Amigo","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054028561","display_name":"Barry H. Paw","orcid":"https://orcid.org/0000-0002-0492-1419","observed_orcids":["https://orcid.org/0000-0002-0492-1419"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Barry H. Paw","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014312110","display_name":"Seth L. Alper","orcid":"https://orcid.org/0000-0002-6228-2512","observed_orcids":["https://orcid.org/0000-0002-6228-2512"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Seth L. Alper","raw_affiliation_strings":[""],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5294,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.62622517,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"294","issue":"3","first_page":"R1081","last_page":"R1091"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12763","display_name":"ATP Synthase and ATPases Research","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/slc4a2","display_name":"SLC4A2","score":0.8050000071525574},{"id":"https://openalex.org/keywords/anion-exchanger","display_name":"anion exchanger","score":0.800000011920929},{"id":"https://openalex.org/keywords/cl-hco3-exchange","display_name":"Cl-/HCO3- exchange","score":0.8130000233650208},{"id":"https://openalex.org/keywords/gene-duplication","display_name":"gene duplication","score":0.4350000023841858},{"id":"https://openalex.org/keywords/xenopus-oocyte-expression-system","display_name":"Xenopus oocyte expression","score":0.6710000038146973},{"id":"https://openalex.org/keywords/pronephric-duct","display_name":"pronephric duct","score":0.7099999785423279},{"id":"https://openalex.org/keywords/gene-knockdown","display_name":"gene knockdown","score":0.7039999961853027},{"id":"https://openalex.org/keywords/mrna-expression-patterns","display_name":"mRNA expression patterns","score":0.4480000138282776},{"id":"https://openalex.org/keywords/zebrafish","display_name":"zebrafish","score":0.5740000009536743}],"concepts":[{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.906816840171814},{"id":"https://openalex.org/C136571751","wikidata":"https://www.wikidata.org/wiki/Q424607","display_name":"Morpholino","level":4,"score":0.6112545728683472},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5876864194869995},{"id":"https://openalex.org/C2780384893","wikidata":"https://www.wikidata.org/wiki/Q901804","display_name":"Danio","level":4,"score":0.5517367124557495},{"id":"https://openalex.org/C2779535977","wikidata":"https://www.wikidata.org/wiki/Q1342298","display_name":"Xenopus","level":3,"score":0.5509620308876038},{"id":"https://openalex.org/C173396325","wikidata":"https://www.wikidata.org/wiki/Q1501275","display_name":"Gene knockdown","level":3,"score":0.5449276566505432},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.531391978263855},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.46112555265426636},{"id":"https://openalex.org/C81439078","wikidata":"https://www.wikidata.org/wiki/Q2304142","display_name":"In situ hybridization","level":4,"score":0.443970263004303},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.4394327700138092},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4274604320526123},{"id":"https://openalex.org/C28406088","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Extracellular","level":2,"score":0.41383570432662964},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32515862584114075},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.253445029258728}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002712","descriptor_name":"Chlorides","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004625","descriptor_name":"Embryo, Nonmammalian","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005455","descriptor_name":"Fluorescent Antibody Technique","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008564","descriptor_name":"Membrane Potentials","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009865","descriptor_name":"Oocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014982","descriptor_name":"Xenopus laevis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017920","descriptor_name":"Antiporters","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018408","descriptor_name":"Patch-Clamp Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D027321","descriptor_name":"Anion Transport Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D027963","descriptor_name":"Chloride-Bicarbonate Antiporters","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064606","descriptor_name":"SLC4A Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1152/ajpregu.00690.2007","doi":"https://doi.org/10.1152/ajpregu.00690.2007","is_oa":false,"landing_page_url":"https://doi.org/10.1152/ajpregu.00690.2007","pdf_url":null,"source":{"id":"https://openalex.org/S59702976","display_name":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","issn_l":"0363-6119","issn":["0363-6119","1522-1490"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320155","host_organization_name":"American Physiological Society","host_organization_lineage":["https://openalex.org/P4310320155"],"host_organization_lineage_names":["American Physiological Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American Journal of Physiology-Regulatory, Integrative and Comparative Physiology","raw_type":"journal-article"},{"id":"pmid:18046018","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18046018","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of physiology. Regulatory, integrative and comparative physiology","raw_type":"Journal Article"},{"id":"pmh:oai:escholarship.umassmed.edu:gsbs_sp-1345","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.umassmed.edu/gsbs_sp/346","pdf_url":null,"source":{"id":"https://openalex.org/S4306400883","display_name":"The Journal of the American Medical Association (JAMA) Network (American Medical Association)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I173654999","host_organization_name":"American Medical Association","host_organization_lineage":["https://openalex.org/I173654999"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Morningside Graduate School of Biomedical Sciences Student Publications","raw_type":"text"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G3096540873","display_name":null,"funder_award_id":"DK 43495","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G4164330655","display_name":"DEVELOPMENTAL BIOLOGY OF HUMAN ERYTHROPOIESIS","funder_award_id":"P01HL032262","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G4188393147","display_name":null,"funder_award_id":"DK-70838","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G4437389272","display_name":"Research Training in Nephrology","funder_award_id":"T32DK007199","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G5166024464","display_name":"Frascati: mitochondrial transporter and erythropoiesis","funder_award_id":"R01DK070838","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G5272302756","display_name":null,"funder_award_id":"HL-32262","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G8889440868","display_name":null,"funder_award_id":"DK-07199","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1492365639","https://openalex.org/W1498737771","https://openalex.org/W1521596432","https://openalex.org/W1536331357","https://openalex.org/W1560262100","https://openalex.org/W2001186370","https://openalex.org/W2001568723","https://openalex.org/W2007832674","https://openalex.org/W2019033622","https://openalex.org/W2033555181","https://openalex.org/W2033565541","https://openalex.org/W2070818399","https://openalex.org/W2092156928","https://openalex.org/W2097128462","https://openalex.org/W2130924644","https://openalex.org/W2140785269","https://openalex.org/W2155475600","https://openalex.org/W2163374738","https://openalex.org/W2201196189"],"related_works":["https://openalex.org/W2140785269","https://openalex.org/W2009819733","https://openalex.org/W4312767759","https://openalex.org/W1522756598","https://openalex.org/W2001568723","https://openalex.org/W2033109182","https://openalex.org/W40115548","https://openalex.org/W2136987808","https://openalex.org/W2061455341","https://openalex.org/W2007832674"],"abstract_inverted_index":{"The":[0,89],"genome":[1],"of":[2,19,22,78,82,92,100,150,178,206,209,213,221,234],"zebrafish":[3,28,85,93,111,182],"(Danio":[4],"rerio)":[5],"encodes":[6,97,125],"two":[7],"unlinked":[8],"genes":[9,18],"equally":[10],"closely":[11],"related":[12],"to":[13],"the":[14,25,73,80,83,201,235,238],"SLC4A2/AE2":[15],"anion":[16,151],"exchanger":[17],"mammals.":[20],"One":[21],"these":[23],"is":[24,141],"recently":[26],"reported":[27],"ae2":[29],"gene":[30,91],"(Shmukler":[31],"BE,":[32],"Kurschat":[33],"CE,":[34],"Ackermann":[35],"GE,":[36],"Jiang":[37],"L,":[38],"Zhou":[39],"Y,":[40],"Barut":[41],"B,":[42],"Stuart-Tilley":[43],"AK,":[44],"Zhao":[45],"J,":[46],"Zon":[47],"LI,":[48],"Drummond":[49],"IA,":[50],"Vandorpe":[51],"DH,":[52],"Paw":[53],"BH,":[54],"Alper":[55],"SL.":[56],"Am":[57],"J":[58],"Physiol":[59,61,63],"Renal":[60,62],"289:":[64],"F835-F849,":[65],"2005),":[66],"now":[67,71],"called":[68],"ae2.1.":[69],"We":[70],"report":[72],"structural":[74],"and":[75,113,135,146,160,167,193,230,237],"functional":[76],"characterization":[77],"Ae2.2,":[79],"product":[81],"second":[84],"Ae2":[86],"gene,":[87],"ae2.2.":[88],"ae2.2":[90],"linkage":[94],"group":[95],"24":[96,242],"a":[98,126],"polypeptide":[99,128],"1,232":[101],"aa":[102],"in":[103,122,181,186,200],"length,":[104],"sharing":[105],"70%":[106],"amino":[107],"acid":[108],"identity":[109,115],"with":[110,116,215],"Ae2.1":[112,210],"67%":[114],"mouse":[117],"AE2a.":[118],"Zebrafish":[119],"Ae2.2":[120,155,179,207],"expressed":[121],"Xenopus":[123],"oocytes":[124],"135-kDa":[127],"that":[129],"mediates":[130],"bidirectional,":[131],"DIDS-sensitive":[132],"Cl(-)/Cl(-)":[133,139],"exchange":[134,140,152],"Cl(-)/HCO3(-)":[136],"exchange.":[137],"Ae2.2-mediated":[138],"cation":[142],"independent,":[143],"voltage":[144],"insensitive,":[145],"electroneutral.":[147],"Acute":[148],"regulation":[149],"mediated":[153],"by":[154,158,163,168],"includes":[156],"activation":[157],"NH4+":[159],"independent":[161],"inhibition":[162],"acidic":[164,169],"intracellular":[165],"pH":[166],"extracellular":[170],"pH.":[171],"In":[172],"situ":[173],"hybridization":[174],"reveals":[175],"low-level":[176],"expression":[177,199],"mRNA":[180],"embryo,":[183],"most":[184],"notably":[185],"posterior":[187],"tectum,":[188],"eye,":[189],"pharynx,":[190],"epidermal":[191],"cells,":[192],"axial":[194],"vascular":[195],"structures,":[196],"without":[197],"notable":[198],"Ae2.1-expressing":[202],"pronephric":[203,239],"duct.":[204],"Knockdown":[205],"mRNA,":[208,211],"or":[212,217],"both":[214],"nontoxic":[216],"minimally":[218],"toxic":[219],"levels":[220],"N-morpholino":[222],"oligomers":[223],"produced":[224],"no":[225],"grossly":[226],"detectable":[227],"morphological":[228],"phenotype,":[229],"preserved":[231],"normal":[232],"structure":[233],"head":[236],"duct":[240],"at":[241],"h":[243],"postfertilization.":[244]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}