{"id":"https://openalex.org/W2037543597","doi":"https://doi.org/10.1097/00002030-200003310-00006","title":"Oral zidovudine during labor to prevent perinatal HIV transmission, Bangkok: tolerance and zidovudine concentration in cord blood","display_name":"Oral zidovudine during labor to prevent perinatal HIV transmission, Bangkok: tolerance and zidovudine concentration in cord blood","publication_year":2000,"publication_date":"2000-03-01","ids":{"openalex":"https://openalex.org/W2037543597","doi":"https://doi.org/10.1097/00002030-200003310-00006","mag":"2037543597","pmid":"https://pubmed.ncbi.nlm.nih.gov/10780713"},"language":"en","primary_location":{"id":"doi:10.1097/00002030-200003310-00006","doi":"https://doi.org/10.1097/00002030-200003310-00006","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00002030-200003310-00006","pdf_url":null,"source":{"id":"https://openalex.org/S20605092","display_name":"AIDS","issn_l":"0269-9370","issn":["0269-9370","1473-5571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110070033","display_name":"Chaiporn Bhadrakom","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1332387789","display_name":"Siriraj Hospital","ror":"https://ror.org/0331zs648","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I1332387789"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Chaiporn Bhadrakom","raw_affiliation_strings":["Siriraj Hospital Faculty of Medicine, Siriraj Hospital, Bangkok, Thailand","Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Siriraj Hospital Faculty of Medicine, Siriraj Hospital, Bangkok, Thailand","institution_ids":["https://openalex.org/I1332387789"]},{"raw_affiliation_string":"Thailand","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113195922","display_name":"R. J. Simonds","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"R. J. Simonds","raw_affiliation_strings":["Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA;","The HIV/AIDS Collaboration, Nonthaburi, Thailand;","Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA;","institution_ids":["https://openalex.org/I1289490764"]},{"raw_affiliation_string":"The HIV/AIDS Collaboration, Nonthaburi, Thailand;","institution_ids":[]},{"raw_affiliation_string":"Thailand","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010667984","display_name":"Joanne V. Mei","orcid":"https://orcid.org/0000-0002-8581-6361","observed_orcids":["https://orcid.org/0000-0002-8581-6361"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joanne V. Mei","raw_affiliation_strings":["Division of Environmental Health Laboratory Sciences, CDC, Atlanta, GA, USA;","Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Environmental Health Laboratory Sciences, CDC, Atlanta, GA, USA;","institution_ids":["https://openalex.org/I1289490764"]},{"raw_affiliation_string":"Thailand","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006616663","display_name":"Suvanna Asavapiriyanont","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1315836254","display_name":"Ministry of Public Health","ror":"https://ror.org/03rn0z073","country_code":"TH","type":"funder","lineage":["https://openalex.org/I1315836254"]},{"id":"https://openalex.org/I4210112079","display_name":"Rajavithi Hospital","ror":"https://ror.org/0238gtq84","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I4210112079"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Suvanna Asavapiriyanont","raw_affiliation_strings":["Rajavithi Hospital, Department of Medical Services (DMS), Ministry of Public Health (MOPH), Bangkok, Thailand;","Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rajavithi Hospital, Department of Medical Services (DMS), Ministry of Public Health (MOPH), Bangkok, Thailand;","institution_ids":["https://openalex.org/I1315836254","https://openalex.org/I4210112079"]},{"raw_affiliation_string":"Thailand","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018515242","display_name":"Varaporn Sangtawesin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1315836254","display_name":"Ministry of Public Health","ror":"https://ror.org/03rn0z073","country_code":"TH","type":"funder","lineage":["https://openalex.org/I1315836254"]},{"id":"https://openalex.org/I4210086785","display_name":"Queen Sirikit National Institute of Child Health","ror":"https://ror.org/000fvwg06","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I4210086785"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Varaporn Sangtaweesin","raw_affiliation_strings":["Queen Sirikit National Institute for Child Health, DMS, MOPH, Bangkok, Thailand; and","Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Queen Sirikit National Institute for Child Health, DMS, MOPH, Bangkok, Thailand; and","institution_ids":["https://openalex.org/I1315836254","https://openalex.org/I4210086785"]},{"raw_affiliation_string":"Thailand","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079747280","display_name":"Nirun Vanprapar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1332387789","display_name":"Siriraj Hospital","ror":"https://ror.org/0331zs648","country_code":"TH","type":"healthcare","lineage":["https://openalex.org/I1332387789"]}],"countries":["TH"],"is_corresponding":false,"raw_author_name":"Nirun Vanprapar","raw_affiliation_strings":["Siriraj Hospital Faculty of Medicine, Siriraj Hospital, Bangkok, Thailand;","Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Siriraj Hospital Faculty of Medicine, Siriraj Hospital, Bangkok, Thailand;","institution_ids":["https://openalex.org/I1332387789"]},{"raw_affiliation_string":"Thailand","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111754267","display_name":"Katy H. P. Moore","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Katy H. P. Moore","raw_affiliation_strings":["Glaxo-Wellcome, Inc., Research Triangle Park, NC, USA","Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glaxo-Wellcome, Inc., Research Triangle Park, NC, USA","institution_ids":[]},{"raw_affiliation_string":"Thailand","institution_ids":[]}]},{"author_position":"middle","author":{"id":null,"display_name":"Nancy L. Young","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nancy L. Young","raw_affiliation_strings":["Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA;","The HIV/AIDS Collaboration, Nonthaburi, Thailand;","Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA;","institution_ids":["https://openalex.org/I1289490764"]},{"raw_affiliation_string":"The HIV/AIDS Collaboration, Nonthaburi, Thailand;","institution_ids":[]},{"raw_affiliation_string":"Thailand","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110157245","display_name":"W. Harry Hannon","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W. Harry Hannon","raw_affiliation_strings":["Division of Environmental Health Laboratory Sciences, CDC, Atlanta, GA, USA;","Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Environmental Health Laboratory Sciences, CDC, Atlanta, GA, USA;","institution_ids":["https://openalex.org/I1289490764"]},{"raw_affiliation_string":"Thailand","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079005738","display_name":"Timothy D. Mastro","orcid":"https://orcid.org/0000-0002-9307-0360","observed_orcids":["https://orcid.org/0000-0002-9307-0360"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Timothy D. Mastro","raw_affiliation_strings":["Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA;","The HIV/AIDS Collaboration, Nonthaburi, Thailand;","Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA;","institution_ids":["https://openalex.org/I1289490764"]},{"raw_affiliation_string":"The HIV/AIDS Collaboration, Nonthaburi, Thailand;","institution_ids":[]},{"raw_affiliation_string":"Thailand","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5018817983","display_name":"Nathan Shaffer","orcid":"https://orcid.org/0000-0001-5332-6301","observed_orcids":["https://orcid.org/0000-0001-5332-6301"]},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"government","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nathan Shaffer","raw_affiliation_strings":["Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA;","The HIV/AIDS Collaboration, Nonthaburi, Thailand;","Thailand"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of HIV/AIDS Prevention, Centers for Disease Control and Prevention (CDC), Atlanta, GA, USA;","institution_ids":["https://openalex.org/I1289490764"]},{"raw_affiliation_string":"The HIV/AIDS Collaboration, Nonthaburi, Thailand;","institution_ids":[]},{"raw_affiliation_string":"Thailand","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5113195922"],"corresponding_institution_ids":["https://openalex.org/I1289490764"],"apc_list":null,"apc_paid":null,"fwci":1.2456,"has_fulltext":false,"cited_by_count":28,"citation_normalized_percentile":{"value":0.79243152,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"14","issue":"5","first_page":"509","last_page":"516"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.8208000063896179,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.8208000063896179,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.17430000007152557,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11964","display_name":"Pregnancy and Medication Impact","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/zidovudine","display_name":"zidovudine","score":0.9959999918937683},{"id":"https://openalex.org/keywords/perinatal-hiv-transmission","display_name":"perinatal HIV transmission","score":0.9340000152587891},{"id":"https://openalex.org/keywords/oral-administration","display_name":"oral administration","score":0.4819999933242798},{"id":"https://openalex.org/keywords/drug-tolerability","display_name":"drug tolerability","score":0.7900000214576721},{"id":"https://openalex.org/keywords/hiv-prevention-in-pregnancy","display_name":"HIV prevention in pregnancy","score":0.47999998927116394}],"concepts":[{"id":"https://openalex.org/C2780216070","wikidata":"https://www.wikidata.org/wiki/Q198504","display_name":"Zidovudine","level":4,"score":0.9110968112945557},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7810197472572327},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.5758318901062012},{"id":"https://openalex.org/C2780914630","wikidata":"https://www.wikidata.org/wiki/Q914952","display_name":"Cord blood","level":2,"score":0.5752319693565369},{"id":"https://openalex.org/C2776955114","wikidata":"https://www.wikidata.org/wiki/Q172563","display_name":"Umbilical cord","level":2,"score":0.4696188271045685},{"id":"https://openalex.org/C2780852908","wikidata":"https://www.wikidata.org/wiki/Q127076","display_name":"Vomiting","level":2,"score":0.4412706792354584},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.44030052423477173},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.41190189123153687},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.3390546441078186},{"id":"https://openalex.org/C131872663","wikidata":"https://www.wikidata.org/wiki/Q5284418","display_name":"Obstetrics","level":1,"score":0.32193487882614136},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2681151330471039},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.16951701045036316},{"id":"https://openalex.org/C2780727368","wikidata":"https://www.wikidata.org/wiki/Q1928978","display_name":"Viral disease","level":3,"score":0.14916718006134033},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.1232556700706482},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09031626582145691},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003430","descriptor_name":"Cross-Sectional Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005312","descriptor_name":"Fetal Blood","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007743","descriptor_name":"Labor, Obstetric","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009325","descriptor_name":"Nausea","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011251","descriptor_name":"Pregnancy Complications, Infectious","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D011863","descriptor_name":"Radioimmunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013785","descriptor_name":"Thailand","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014839","descriptor_name":"Vomiting","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D015215","descriptor_name":"Zidovudine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D015215","descriptor_name":"Zidovudine","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015215","descriptor_name":"Zidovudine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D015658","descriptor_name":"HIV Infections","qualifier_ui":"Q000821","qualifier_name":"virology","is_major_topic":false},{"descriptor_ui":"D018445","descriptor_name":"Infectious Disease Transmission, Vertical","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000493","qualifier_name":"pharmacokinetics","is_major_topic":false},{"descriptor_ui":"D019380","descriptor_name":"Anti-HIV Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/00002030-200003310-00006","doi":"https://doi.org/10.1097/00002030-200003310-00006","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00002030-200003310-00006","pdf_url":null,"source":{"id":"https://openalex.org/S20605092","display_name":"AIDS","issn_l":"0269-9370","issn":["0269-9370","1473-5571"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS","raw_type":"journal-article"},{"id":"pmid:10780713","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10780713","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"AIDS (London, England)","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320315488","display_name":"ACT Government","ror":"https://ror.org/03fy7b149"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":18,"referenced_works":["https://openalex.org/W101659629","https://openalex.org/W1975689647","https://openalex.org/W1994613586","https://openalex.org/W1998204576","https://openalex.org/W2003983757","https://openalex.org/W2097921592","https://openalex.org/W2104853744","https://openalex.org/W2143773220","https://openalex.org/W2170947401","https://openalex.org/W2282853564","https://openalex.org/W2316970929","https://openalex.org/W2318503132","https://openalex.org/W2329848955","https://openalex.org/W2329960468","https://openalex.org/W2337158409","https://openalex.org/W2613550240","https://openalex.org/W3021428065","https://openalex.org/W4245567163"],"related_works":["https://openalex.org/W1964427170","https://openalex.org/W1527761365","https://openalex.org/W2329848955","https://openalex.org/W2282421395","https://openalex.org/W2104853744","https://openalex.org/W2467937606","https://openalex.org/W2282853564","https://openalex.org/W4292255688","https://openalex.org/W2053145710","https://openalex.org/W1558389229"],"abstract_inverted_index":{"OBJECTIVES:":[0],"To":[1],"evaluate":[2],"tolerance":[3],"for":[4,84],"the":[5,15,74,79,98,130,139,143,163,219,240,275],"oral":[6,244],"administration":[7],"of":[8,27,33,116,136],"zidovudine":[9],"(ZDV)":[10],"during":[11,49,246],"labor":[12,44,105,186,247],"and":[13,45,67,118,197,233,279],"measure":[14],"resulting":[16],"ZDV":[17,35,75,85,99,137,144,211,230,237],"concentrations":[18,174,238,251,263],"in":[19,29,56,73,78,97,138,142,171,178,190,200,239],"umbilical":[20],"cord":[21,60,140,241],"blood.":[22],"DESIGN:":[23],"A":[24],"cross-sectional":[25],"study":[26],"women":[28,71,96,181],"a":[30,37,126],"placebo-controlled":[31],"trial":[32],"short-course":[34],"(twice":[36],"day":[38],"from":[39,69,180],"36":[40],"weeks'":[41],"gestation":[42],"until":[43],"every":[46],"3":[47,114],"h":[48,115],"labor)":[50],"to":[51,129,166],"prevent":[52],"perinatal":[53,225,268],"HIV":[54,170],"transmission":[55],"Bangkok.":[57],"METHODS:":[58],"Umbilical":[59],"blood":[61,141,242],"was":[62,146,213,231],"collected.":[63],"Sixty":[64],"control":[65],"specimens":[66,68,155,179],"372":[70],"(182":[72],"group,":[76],"190":[77],"placebo":[80,131],"group)":[81],"were":[82,156,175,248,253,264],"tested":[83],"by":[86],"radioimmunoassay":[87],"(lower":[88],"detection":[89],"limit":[90],"<":[91,150,208],"1":[92],"ng/ml).":[93],"RESULTS:":[94],"All":[95],"group":[100,145],"took":[101,109],"one":[102,183],"or":[103,124,184,194,224],"more":[104,203],"dose,":[106,221],"170":[107],"(93%)":[108],"their":[110],"last":[111,220],"dose":[112],"within":[113],"delivery,":[117],"only":[119],"five":[120],"(3%)":[121],"experienced":[122],"nausea":[123],"vomiting,":[125],"proportion":[127],"similar":[128],"group.":[132],"The":[133,210],"median":[134],"concentration":[135,164,212],"252":[147],"ng/ml":[148,160,177,189,199],"(range,":[149],"1-1133":[151],"ng/ml);":[152],"31":[153],"(17%)":[154],"less":[157],"than":[158,204,255],"130":[159],"(0.5":[161],"microM),":[162],"thought":[165],"be":[167],"active":[168],"against":[169],"vitro.":[172],"Median":[173],"189":[176],"taking":[182,192,202],"two":[185],"doses,":[187,196],"290":[188],"those":[191,201,256],"three":[193],"four":[195,205],"293":[198],"doses":[206],"(P":[207],"0.01).":[209],"not":[214,265,273],"associated":[215,266],"with":[216,267],"time":[217],"since":[218],"body":[222],"weight,":[223],"transmission.":[226],"CONCLUSION:":[227],"Oral":[228],"intrapartum":[229,278],"feasible":[232],"well":[234],"tolerated.":[235],"Most":[236],"after":[243,258],"dosing":[245],"at":[249],"therapeutic":[250],"but":[252],"lower":[254],"reported":[257],"continuous":[259],"intravenous":[260],"administration.":[261],"Although":[262],"transmission,":[269],"these":[270],"data":[271],"do":[272],"exclude":[274],"possibility":[276],"that":[277],"neonatal":[280],"chemoprophylaxis":[281],"is":[282],"effective.":[283]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}