{"id":"https://openalex.org/W2037215946","doi":"https://doi.org/10.2170/jjphysiol.31.99","title":"Effect of acid-base status in vivo on Bicarbonate transport by rabbit renal tubules in vitro.","display_name":"Effect of acid-base status in vivo on Bicarbonate transport by rabbit renal tubules in vitro.","publication_year":1981,"publication_date":"1981-01-01","ids":{"openalex":"https://openalex.org/W2037215946","doi":"https://doi.org/10.2170/jjphysiol.31.99","mag":"2037215946","pmid":"https://pubmed.ncbi.nlm.nih.gov/6792408"},"language":"en","primary_location":{"id":"doi:10.2170/jjphysiol.31.99","doi":"https://doi.org/10.2170/jjphysiol.31.99","is_oa":true,"landing_page_url":"https://doi.org/10.2170/jjphysiol.31.99","pdf_url":"https://www.jstage.jst.go.jp/article/jjphysiol1950/31/1/31_1_99/_pdf","source":{"id":"https://openalex.org/S47046129","display_name":"The Japanese Journal of Physiology","issn_l":"0021-521X","issn":["0021-521X","1881-1396"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4320800725","host_organization_name":"Physiological Society of Japan","host_organization_lineage":["https://openalex.org/P4320800725"],"host_organization_lineage_names":["Physiological Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Japanese Journal of Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/jjphysiol1950/31/1/31_1_99/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112657816","display_name":"Yasuhiko Iino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yasuhiko IINO","raw_affiliation_strings":["Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025916093","display_name":"Maurice B. Burg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maurice B. BURG","raw_affiliation_strings":["Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung, and Blood Institute, National Institutes of Health","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.685,"has_fulltext":true,"cited_by_count":36,"citation_normalized_percentile":{"value":0.91999015,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"31","issue":"1","first_page":"99","last_page":"107"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12840","display_name":"Renal function and acid-base balance","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12840","display_name":"Renal function and acid-base balance","score":0.9775000214576721,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.021400000900030136,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bicarbonate-transport","display_name":"bicarbonate transport","score":0.9869999885559082},{"id":"https://openalex.org/keywords/renal-tubules","display_name":"renal tubules","score":0.8050000071525574},{"id":"https://openalex.org/keywords/acid-base-status","display_name":"acid-base status","score":0.9380000233650208},{"id":"https://openalex.org/keywords/acidosis","display_name":"acidosis","score":0.6970000267028809},{"id":"https://openalex.org/keywords/alkalosis","display_name":"alkalosis","score":0.9990000128746033},{"id":"https://openalex.org/keywords/cortical-collecting-duct","display_name":"cortical collecting duct","score":0.8899999856948853},{"id":"https://openalex.org/keywords/proximal-straight-tubule","display_name":"proximal straight tubule","score":0.9789999723434448},{"id":"https://openalex.org/keywords/thick-ascending-limb","display_name":"thick ascending limb","score":0.8920000195503235},{"id":"https://openalex.org/keywords/chloride-uptake","display_name":"chloride uptake","score":0.8849999904632568},{"id":"https://openalex.org/keywords/bicarbonate-excretion","display_name":"bicarbonate excretion","score":0.8410000205039978},{"id":"https://openalex.org/keywords/rabbits","display_name":"rabbits","score":0.4309999942779541}],"concepts":[{"id":"https://openalex.org/C2781112554","wikidata":"https://www.wikidata.org/wiki/Q409202","display_name":"Bicarbonate","level":2,"score":0.933171272277832},{"id":"https://openalex.org/C2776420369","wikidata":"https://www.wikidata.org/wiki/Q179731","display_name":"Sodium bicarbonate","level":2,"score":0.6532701253890991},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.5451622605323792},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5398312211036682},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5137330293655396},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5071167945861816},{"id":"https://openalex.org/C134746045","wikidata":"https://www.wikidata.org/wiki/Q3275718","display_name":"Acid\u2013base homeostasis","level":2,"score":0.49976563453674316},{"id":"https://openalex.org/C158171629","wikidata":"https://www.wikidata.org/wiki/Q6998414","display_name":"Net acid excretion","level":3,"score":0.49209707975387573},{"id":"https://openalex.org/C537181965","wikidata":"https://www.wikidata.org/wiki/Q658","display_name":"Sodium","level":2,"score":0.4498172104358673},{"id":"https://openalex.org/C10146269","wikidata":"https://www.wikidata.org/wiki/Q185557","display_name":"Excretion","level":2,"score":0.4497506320476532},{"id":"https://openalex.org/C2781231759","wikidata":"https://www.wikidata.org/wiki/Q58184","display_name":"Nephron","level":3,"score":0.4346766471862793},{"id":"https://openalex.org/C2778695967","wikidata":"https://www.wikidata.org/wiki/Q44791900","display_name":"Chloride","level":2,"score":0.41995227336883545},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.3422676920890808},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.29214566946029663},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.13665813207626343},{"id":"https://openalex.org/C147789679","wikidata":"https://www.wikidata.org/wiki/Q11372","display_name":"Physical chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000643","descriptor_name":"Ammonium Chloride","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001639","descriptor_name":"Bicarbonates","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001692","descriptor_name":"Biological Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002245","descriptor_name":"Carbon Dioxide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002250","descriptor_name":"Carbon Radioisotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006863","descriptor_name":"Hydrogen-Ion Concentration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007684","descriptor_name":"Kidney Tubules","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007686","descriptor_name":"Kidney Tubules, Distal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007687","descriptor_name":"Kidney Tubules, Proximal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D066298","descriptor_name":"In Vitro Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.2170/jjphysiol.31.99","doi":"https://doi.org/10.2170/jjphysiol.31.99","is_oa":true,"landing_page_url":"https://doi.org/10.2170/jjphysiol.31.99","pdf_url":"https://www.jstage.jst.go.jp/article/jjphysiol1950/31/1/31_1_99/_pdf","source":{"id":"https://openalex.org/S47046129","display_name":"The Japanese Journal of Physiology","issn_l":"0021-521X","issn":["0021-521X","1881-1396"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4320800725","host_organization_name":"Physiological Society of Japan","host_organization_lineage":["https://openalex.org/P4320800725"],"host_organization_lineage_names":["Physiological Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Japanese Journal of Physiology","raw_type":"journal-article"},{"id":"pmid:6792408","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6792408","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Japanese journal of physiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.2170/jjphysiol.31.99","doi":"https://doi.org/10.2170/jjphysiol.31.99","is_oa":true,"landing_page_url":"https://doi.org/10.2170/jjphysiol.31.99","pdf_url":"https://www.jstage.jst.go.jp/article/jjphysiol1950/31/1/31_1_99/_pdf","source":{"id":"https://openalex.org/S47046129","display_name":"The Japanese Journal of Physiology","issn_l":"0021-521X","issn":["0021-521X","1881-1396"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4320800725","host_organization_name":"Physiological Society of Japan","host_organization_lineage":["https://openalex.org/P4320800725"],"host_organization_lineage_names":["Physiological Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Japanese Journal of Physiology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2037215946.pdf","grobid_xml":"https://content.openalex.org/works/W2037215946.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W1579899042","https://openalex.org/W1984635589","https://openalex.org/W1996594976","https://openalex.org/W2000410542","https://openalex.org/W2019401494","https://openalex.org/W2026380015","https://openalex.org/W2049369395","https://openalex.org/W2055288817","https://openalex.org/W2143849587","https://openalex.org/W2188551092","https://openalex.org/W2341957640","https://openalex.org/W2403464624","https://openalex.org/W2410102011","https://openalex.org/W2410203954","https://openalex.org/W2430026476","https://openalex.org/W2460609464","https://openalex.org/W3023044114","https://openalex.org/W6603437634"],"related_works":["https://openalex.org/W2019401494","https://openalex.org/W1984635589","https://openalex.org/W2466107741","https://openalex.org/W7099655126","https://openalex.org/W2438430319","https://openalex.org/W2416165468","https://openalex.org/W1963594105","https://openalex.org/W3023044114","https://openalex.org/W2338932258","https://openalex.org/W2066532476"],"abstract_inverted_index":{"In":[0,78],"previous":[1],"studies,":[2],"when":[3],"rabbit":[4],"cortical":[5,109,135,177],"collecting":[6,35,167],"ducts":[7,36,168],"were":[8,32,42,55,106,139],"studied":[9],"under":[10],"standard":[11],"conditions":[12],"in":[13,23,74,149,166,171,176,181],"vitro,":[14],"bicarbonate":[15,38,51,59,90,123,153,163],"transport":[16,121,143,164],"was":[17,67,92,114,118],"conditioned":[18],"by":[19,95,124],"the":[20,26,30,40,53,64,83,86,96,100,104,150,158,182],"acid-base":[21,97],"status":[22,98],"vivo":[24],"of":[25,63,89,99,122,152,162],"animals":[27,41,54,101],"from":[28,102,129],"which":[29,103],"tubules":[31,81,105,125,174],"obtained.":[33,107],"The":[34,61],"absorbed":[37],"if":[39,52],"acidotic":[43,130],"(from":[44,57],"ammonium":[45],"chloride":[46,113],"administration),":[47],"but":[48,116,169],"they":[49,127,145],"secreted":[50],"alkalotic":[56,132],"sodium":[58],"administration).":[60],"purpose":[62],"present":[65],"studies":[66],"to":[68,142],"test":[69],"whether":[70,126],"similar":[71],"conditioning":[72,161],"occurs":[73,165],"other":[75],"nephron":[76],"segments.":[77],"proximal":[79,172],"straight":[80,173],"neither":[82],"sodium-dependent":[84],"nor":[85],"sodium-independent":[87],"component":[88],"absorption":[91],"significantly":[93],"affected":[94],".In":[108],"thick":[110,136,178],"ascending":[111,137,179],"limbs,":[112],"absorbed,":[115],"there":[117],"no":[119],"net":[120],"came":[128],"or":[131,175],"animals.":[133],"Since":[134],"limbs":[138,180],"not":[140,170],"found":[141],"bicarbonate,":[144],"cannot":[146],"be":[147],"implicated":[148],"control":[151],"excretion.":[154],"We":[155],"conclude":[156],"that":[157],"previously":[159],"observed":[160],"same":[183],"experimental":[184],"situation.":[185]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}