{"id":"https://openalex.org/W2037061346","doi":"https://doi.org/10.1002/chin.199429200","title":"ChemInform Abstract: Synthesis and Evaluation of Tacrine\u2010Related Compounds for the Treatment of Alzheimer\u2032s Disease.","display_name":"ChemInform Abstract: Synthesis and Evaluation of Tacrine\u2010Related Compounds for the Treatment of Alzheimer\u2032s Disease.","publication_year":1994,"publication_date":"1994-07-19","ids":{"openalex":"https://openalex.org/W2037061346","doi":"https://doi.org/10.1002/chin.199429200","mag":"2037061346"},"language":"en","primary_location":{"id":"doi:10.1002/chin.199429200","doi":"https://doi.org/10.1002/chin.199429200","is_oa":false,"landing_page_url":"https://doi.org/10.1002/chin.199429200","pdf_url":null,"source":{"id":"https://openalex.org/S41354064","display_name":"ChemInform","issn_l":"0009-2975","issn":["0009-2975","0931-7597","1431-5890","1522-2667","2199-2924"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ChemInform","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078282536","display_name":"F. AGUADO","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"F. AGUADO","raw_affiliation_strings":["Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103582617","display_name":"Albert Bad\u0131\u0301a","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"A. BADIA","raw_affiliation_strings":["Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060163707","display_name":"Josep-Elad\u0131\u0301 Ba\u00f1os","orcid":"https://orcid.org/0000-0001-8202-6893","observed_orcids":["https://orcid.org/0000-0001-8202-6893"]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"J. E. BANOS","raw_affiliation_strings":["Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025693745","display_name":"F\u00e8lix Bosch","orcid":"https://orcid.org/0000-0002-2284-1834","observed_orcids":["https://orcid.org/0000-0002-2284-1834","https://orcid.org/0000-0002-7172-3412"]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"F. BOSCH","raw_affiliation_strings":["Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054455819","display_name":"Consol Bozzo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"C. BOZZO","raw_affiliation_strings":["Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049250189","display_name":"Pelayo Camps","orcid":"https://orcid.org/0000-0002-9633-3525","observed_orcids":["https://orcid.org/0000-0002-9633-3525"]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"P. CAMPS","raw_affiliation_strings":["Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J. CONTRERAS","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"J. CONTRERAS","raw_affiliation_strings":["Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010534544","display_name":"Mara Dierssen","orcid":"https://orcid.org/0000-0003-0853-6865","observed_orcids":["https://orcid.org/0000-0003-0853-6865"]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"M. DIERSSEN","raw_affiliation_strings":["Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017299571","display_name":"Carmen Escolano","orcid":"https://orcid.org/0000-0002-9117-8239","observed_orcids":["https://orcid.org/0000-0002-9117-8239"]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"C. ESCOLANO","raw_affiliation_strings":["Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034698636","display_name":"D. M. GOERBIG","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"D. M. GOERBIG","raw_affiliation_strings":["Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008514402","display_name":"Diego Mu\u00f1oz\u2010Torrero","orcid":"https://orcid.org/0000-0002-8140-8555","observed_orcids":["https://orcid.org/0000-0002-8140-8555"]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"D. MUNOZ\u2010TORRERO","raw_affiliation_strings":["Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010893509","display_name":"Mar\u00eda Dolors Pujol","orcid":"https://orcid.org/0000-0003-1061-034X","observed_orcids":["https://orcid.org/0000-0003-1061-034X"]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"M. D. PUJOL","raw_affiliation_strings":["Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062315680","display_name":"Montserrat Sim\u00f3n","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"M. SIMON","raw_affiliation_strings":["Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068726774","display_name":"M. T. VAZQUEZ","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"M. T. VAZQUEZ","raw_affiliation_strings":["Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110343208","display_name":"Nuria Mar\u00eda Vivas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I71999127","display_name":"Universitat de Barcelona","ror":"https://ror.org/021018s57","country_code":"ES","type":"education","lineage":["https://openalex.org/I71999127"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"N. M. VIVAS","raw_affiliation_strings":["Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lab. Quim. Farm., Fac. Farm., Univ. Barcelona, 08028 Barcelona, Spain","institution_ids":["https://openalex.org/I71999127"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I71999127"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.13478319,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"25","issue":"29","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12023","display_name":"Cholinesterase and Neurodegenerative Diseases","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12023","display_name":"Cholinesterase and Neurodegenerative Diseases","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.005400000140070915,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10274","display_name":"Synthesis and biological activity","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tacrine","display_name":"tacrine","score":0.9639999866485596},{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":0.984000027179718},{"id":"https://openalex.org/keywords/acetylcholinesterase-inhibitors","display_name":"acetylcholinesterase inhibitors","score":0.8899999856948853},{"id":"https://openalex.org/keywords/drug-synthesis","display_name":"drug synthesis","score":0.75}],"concepts":[{"id":"https://openalex.org/C2779046751","wikidata":"https://www.wikidata.org/wiki/Q421076","display_name":"Tacrine","level":4,"score":0.953052282333374},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9250117540359497},{"id":"https://openalex.org/C2780378061","wikidata":"https://www.wikidata.org/wiki/Q25351891","display_name":"Service (business)","level":2,"score":0.49140894412994385},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.42825090885162354},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.3525288701057434},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.21998223662376404},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.07622087001800537},{"id":"https://openalex.org/C162853370","wikidata":"https://www.wikidata.org/wiki/Q39809","display_name":"Marketing","level":1,"score":0.04829591512680054},{"id":"https://openalex.org/C2778816929","wikidata":"https://www.wikidata.org/wiki/Q22676679","display_name":"Acetylcholinesterase","level":3,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/chin.199429200","doi":"https://doi.org/10.1002/chin.199429200","is_oa":false,"landing_page_url":"https://doi.org/10.1002/chin.199429200","pdf_url":null,"source":{"id":"https://openalex.org/S41354064","display_name":"ChemInform","issn_l":"0009-2975","issn":["0009-2975","0931-7597","1431-5890","1522-2667","2199-2924"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ChemInform","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W2953341487"],"related_works":["https://openalex.org/W2951871437","https://openalex.org/W2949660053","https://openalex.org/W2949562454","https://openalex.org/W2044632501","https://openalex.org/W2950524774","https://openalex.org/W2399512566","https://openalex.org/W2411960684","https://openalex.org/W2949633342","https://openalex.org/W2414810644","https://openalex.org/W2953341487"],"abstract_inverted_index":{"Abstract":[0,25],"ChemInform":[1,24],"is":[2,42],"a":[3,11,23,35],"weekly":[4],"Abstracting":[5],"Service,":[6],"delivering":[7],"concise":[8],"information":[9],"at":[10],"glance":[12],"that":[13],"was":[14,30],"extracted":[15],"from":[16],"about":[17],"100":[18],"leading":[19],"journals.":[20],"To":[21],"access":[22],"of":[26],"an":[27],"article":[28,41],"which":[29],"published":[31],"elsewhere,":[32],"please":[33],"select":[34],"\u201cFull":[36],"Text\u201d":[37],"option.":[38,47],"The":[39],"original":[40],"trackable":[43],"via":[44],"the":[45],"\u201cReferences\u201d":[46]},"counts_by_year":[],"updated_date":"2026-10-29T09:56:32.521200","created_date":"2016-06-24T00:00:00"}