{"id":"https://openalex.org/W2036734384","doi":"https://doi.org/10.2174/1876388x01002010012","title":"Genetic and Blood Biomarkers of Alzheimer`s Disease","display_name":"Genetic and Blood Biomarkers of Alzheimer`s Disease","publication_year":2010,"publication_date":"2010-11-29","ids":{"openalex":"https://openalex.org/W2036734384","doi":"https://doi.org/10.2174/1876388x01002010012","mag":"2036734384"},"language":"en","primary_location":{"id":"doi:10.2174/1876388x01002010012","doi":"https://doi.org/10.2174/1876388x01002010012","is_oa":true,"landing_page_url":"https://doi.org/10.2174/1876388x01002010012","pdf_url":"http://benthamopen.com/contents/pdf/TONMEDJ/TONMEDJ-2-12.pdf","source":{"id":"https://openalex.org/S71159475","display_name":"The Open Nuclear Medicine Journal","issn_l":"1876-388X","issn":["1876-388X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Open Nuclear Medicine Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://benthamopen.com/contents/pdf/TONMEDJ/TONMEDJ-2-12.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5018429059","display_name":"Parastoo Momeni","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I12315562","display_name":"Texas Tech University","ror":"https://ror.org/0405mnx93","country_code":"US","type":"education","lineage":["https://openalex.org/I12315562"]},{"id":"https://openalex.org/I926076166","display_name":"Texas Tech University Health Sciences Center","ror":"https://ror.org/033ztpr93","country_code":"US","type":"education","lineage":["https://openalex.org/I926076166"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Parastoo Momeni","raw_affiliation_strings":["Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, 3601 4th St. STOP 9410, Lubbock, Texas 79430, USA","Laboratory of Neurogenetics, Department of Internal Medicine, Texas Tech University Health Sciences Center, 3601 4th St. STOP 9410, Lubbock, Texas 79430, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, 3601 4th St. STOP 9410, Lubbock, Texas 79430, USA","institution_ids":["https://openalex.org/I12315562","https://openalex.org/I926076166"]},{"raw_affiliation_string":"Laboratory of Neurogenetics, Department of Internal Medicine, Texas Tech University Health Sciences Center, 3601 4th St. STOP 9410, Lubbock, Texas 79430, USA","institution_ids":["https://openalex.org/I12315562","https://openalex.org/I926076166"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5107908441","display_name":"Raffaele Ferrari","orcid":"https://orcid.org/0000-0002-6208-5260","observed_orcids":["https://orcid.org/0000-0002-6208-5260"]},"institutions":[{"id":"https://openalex.org/I12315562","display_name":"Texas Tech University","ror":"https://ror.org/0405mnx93","country_code":"US","type":"education","lineage":["https://openalex.org/I12315562"]},{"id":"https://openalex.org/I4405260083","display_name":"UCL Queen Square Institute of Neurology","ror":"https://ror.org/0370htr03","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I45129253","display_name":"University College London","ror":"https://ror.org/02jx3x895","country_code":"GB","type":"education","lineage":["https://openalex.org/I124357947","https://openalex.org/I45129253"]},{"id":"https://openalex.org/I926076166","display_name":"Texas Tech University Health Sciences Center","ror":"https://ror.org/033ztpr93","country_code":"US","type":"education","lineage":["https://openalex.org/I926076166"]}],"countries":["GB","US"],"is_corresponding":false,"raw_author_name":"Raffaele Ferrari","raw_affiliation_strings":["Institute of Neurology, University College London, Queen Sq., London WC1N 3BG, UK","Laboratory of Neurogenetics, Department of Internal Medicine, Texas Tech University Health Sciences Center, 3601 4th St. STOP 9410, Lubbock, Texas 79430, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Neurology, University College London, Queen Sq., London WC1N 3BG, UK","institution_ids":["https://openalex.org/I4405260083","https://openalex.org/I45129253"]},{"raw_affiliation_string":"Laboratory of Neurogenetics, Department of Internal Medicine, Texas Tech University Health Sciences Center, 3601 4th St. STOP 9410, Lubbock, Texas 79430, USA","institution_ids":["https://openalex.org/I12315562","https://openalex.org/I926076166"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5018429059"],"corresponding_institution_ids":["https://openalex.org/I12315562","https://openalex.org/I926076166"],"apc_list":null,"apc_paid":null,"fwci":0.4329,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.67643411,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"2","issue":"1","first_page":"12","last_page":"24"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.5737000107765198,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.5737000107765198,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.42410001158714294,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alzheimer-s-disease","display_name":"Alzheimer's disease","score":1.0},{"id":"https://openalex.org/keywords/blood-biomarkers","display_name":"blood biomarkers","score":0.8199999928474426},{"id":"https://openalex.org/keywords/genetic-biomarkers","display_name":"genetic biomarkers","score":0.9200000166893005},{"id":"https://openalex.org/keywords/peripheral-blood-mononuclear-cells","display_name":"peripheral blood mononuclear cells","score":0.8889999985694885},{"id":"https://openalex.org/keywords/circulating-micrornas","display_name":"circulating microRNAs","score":0.6439999938011169},{"id":"https://openalex.org/keywords/circulating-mrna","display_name":"circulating mRNA","score":0.7279999852180481},{"id":"https://openalex.org/keywords/serum-proteins","display_name":"serum proteins","score":0.6679999828338623},{"id":"https://openalex.org/keywords/plasma-biomarkers","display_name":"plasma biomarkers","score":0.8370000123977661},{"id":"https://openalex.org/keywords/early-detection","display_name":"early detection","score":0.5920000076293945},{"id":"https://openalex.org/keywords/differential-diagnosis-of-dementia","display_name":"differential diagnosis of dementia","score":0.9340000152587891},{"id":"https://openalex.org/keywords/alzheimer-s-disease-pathogenesis","display_name":"Alzheimer's disease pathogenesis","score":0.796999990940094},{"id":"https://openalex.org/keywords/whole-genome-association-studies","display_name":"whole-genome association studies","score":0.7400000095367432},{"id":"https://openalex.org/keywords/heritability","display_name":"heritability","score":0.5770000219345093}],"concepts":[{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.7069856524467468},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.628814160823822},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.598333477973938},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.5394407510757446},{"id":"https://openalex.org/C137061746","wikidata":"https://www.wikidata.org/wiki/Q736033","display_name":"Peripheral blood mononuclear cell","level":3,"score":0.5143250226974487},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.5089802742004395},{"id":"https://openalex.org/C502032728","wikidata":"https://www.wikidata.org/wiki/Q11081","display_name":"Alzheimer's disease","level":3,"score":0.48489075899124146},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.47258317470550537},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.46983951330184937},{"id":"https://openalex.org/C207886595","wikidata":"https://www.wikidata.org/wiki/Q1456138","display_name":"Pathological","level":2,"score":0.46179652214050293},{"id":"https://openalex.org/C46111723","wikidata":"https://www.wikidata.org/wiki/Q471857","display_name":"Proteomics","level":3,"score":0.4334554076194763},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.416026771068573},{"id":"https://openalex.org/C2779529041","wikidata":"https://www.wikidata.org/wiki/Q22349364","display_name":"Liquid biopsy","level":3,"score":0.4142528474330902},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.33610546588897705},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3314083516597748},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.32060396671295166},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.25639989972114563},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.21785706281661987},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15212556719779968},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.11128276586532593},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.2174/1876388x01002010012","doi":"https://doi.org/10.2174/1876388x01002010012","is_oa":true,"landing_page_url":"https://doi.org/10.2174/1876388x01002010012","pdf_url":"http://benthamopen.com/contents/pdf/TONMEDJ/TONMEDJ-2-12.pdf","source":{"id":"https://openalex.org/S71159475","display_name":"The Open Nuclear Medicine Journal","issn_l":"1876-388X","issn":["1876-388X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Open Nuclear Medicine Journal","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.2174/1876388x01002010012","doi":"https://doi.org/10.2174/1876388x01002010012","is_oa":true,"landing_page_url":"https://doi.org/10.2174/1876388x01002010012","pdf_url":"http://benthamopen.com/contents/pdf/TONMEDJ/TONMEDJ-2-12.pdf","source":{"id":"https://openalex.org/S71159475","display_name":"The Open Nuclear Medicine Journal","issn_l":"1876-388X","issn":["1876-388X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Open Nuclear Medicine Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2036734384.pdf","grobid_xml":"https://content.openalex.org/works/W2036734384.grobid-xml"},"referenced_works_count":197,"referenced_works":["https://openalex.org/W32204808","https://openalex.org/W35197623","https://openalex.org/W91108901","https://openalex.org/W99657538","https://openalex.org/W1259396709","https://openalex.org/W1508811801","https://openalex.org/W1511517753","https://openalex.org/W1527694987","https://openalex.org/W1546262989","https://openalex.org/W1569630040","https://openalex.org/W1575230904","https://openalex.org/W1602655991","https://openalex.org/W1729585270","https://openalex.org/W1767636024","https://openalex.org/W1854850313","https://openalex.org/W1926851645","https://openalex.org/W1934903117","https://openalex.org/W1964037917","https://openalex.org/W1966459208","https://openalex.org/W1966613471","https://openalex.org/W1966831712","https://openalex.org/W1967922486","https://openalex.org/W1968155895","https://openalex.org/W1968300632","https://openalex.org/W1969271586","https://openalex.org/W1970723883","https://openalex.org/W1971735349","https://openalex.org/W1972349970","https://openalex.org/W1972380966","https://openalex.org/W1972488785","https://openalex.org/W1973045469","https://openalex.org/W1974604086","https://openalex.org/W1974678833","https://openalex.org/W1978290642","https://openalex.org/W1978853688","https://openalex.org/W1981506621","https://openalex.org/W1986624196","https://openalex.org/W1991413414","https://openalex.org/W1993383247","https://openalex.org/W1993868853","https://openalex.org/W1995006422","https://openalex.org/W1995175521","https://openalex.org/W1995335058","https://openalex.org/W1997460269","https://openalex.org/W1998030446","https://openalex.org/W1998840552","https://openalex.org/W1999369934","https://openalex.org/W1999631936","https://openalex.org/W2001688761","https://openalex.org/W2003933765","https://openalex.org/W2006534012","https://openalex.org/W2007056331","https://openalex.org/W2007929153","https://openalex.org/W2008352401","https://openalex.org/W2009427803","https://openalex.org/W2010245335","https://openalex.org/W2010556599","https://openalex.org/W2011172106","https://openalex.org/W2011410834","https://openalex.org/W2011625746","https://openalex.org/W2013516090","https://openalex.org/W2013615040","https://openalex.org/W2015372700","https://openalex.org/W2017079501","https://openalex.org/W2017231145","https://openalex.org/W2017260345","https://openalex.org/W2017581860","https://openalex.org/W2019675682","https://openalex.org/W2020089910","https://openalex.org/W2021181758","https://openalex.org/W2021254641","https://openalex.org/W2022227326","https://openalex.org/W2025774809","https://openalex.org/W2025935592","https://openalex.org/W2026048677","https://openalex.org/W2030989440","https://openalex.org/W2033518963","https://openalex.org/W2034968148","https://openalex.org/W2036362108","https://openalex.org/W2036450484","https://openalex.org/W2036736258","https://openalex.org/W2038354418","https://openalex.org/W2038416229","https://openalex.org/W2039367496","https://openalex.org/W2040375868","https://openalex.org/W2041393510","https://openalex.org/W2041394188","https://openalex.org/W2042544016","https://openalex.org/W2042902316","https://openalex.org/W2043533659","https://openalex.org/W2044451567","https://openalex.org/W2045445076","https://openalex.org/W2046209489","https://openalex.org/W2047219385","https://openalex.org/W2047304481","https://openalex.org/W2047609464","https://openalex.org/W2048253779","https://openalex.org/W2053152816","https://openalex.org/W2053774830","https://openalex.org/W2054874422","https://openalex.org/W2057290284","https://openalex.org/W2058401000","https://openalex.org/W2058723245","https://openalex.org/W2061576298","https://openalex.org/W2061671780","https://openalex.org/W2061880413","https://openalex.org/W2062043632","https://openalex.org/W2063223047","https://openalex.org/W2064426421","https://openalex.org/W2065184319","https://openalex.org/W2066450419","https://openalex.org/W2066920898","https://openalex.org/W2067820958","https://openalex.org/W2068631553","https://openalex.org/W2069121057","https://openalex.org/W2070742699","https://openalex.org/W2071064041","https://openalex.org/W2072691846","https://openalex.org/W2073051320","https://openalex.org/W2073450860","https://openalex.org/W2073809577","https://openalex.org/W2075555698","https://openalex.org/W2077595053","https://openalex.org/W2079402113","https://openalex.org/W2081140305","https://openalex.org/W2082665846","https://openalex.org/W2085789847","https://openalex.org/W2086264330","https://openalex.org/W2086363884","https://openalex.org/W2087255758","https://openalex.org/W2087574229","https://openalex.org/W2088471254","https://openalex.org/W2088634525","https://openalex.org/W2089442400","https://openalex.org/W2090236009","https://openalex.org/W2090710011","https://openalex.org/W2091847762","https://openalex.org/W2091924214","https://openalex.org/W2092522921","https://openalex.org/W2093150481","https://openalex.org/W2094532272","https://openalex.org/W2096410114","https://openalex.org/W2096486324","https://openalex.org/W2098245087","https://openalex.org/W2098306153","https://openalex.org/W2101397596","https://openalex.org/W2102493638","https://openalex.org/W2103163836","https://openalex.org/W2108325105","https://openalex.org/W2108545106","https://openalex.org/W2114295161","https://openalex.org/W2116784956","https://openalex.org/W2119679926","https://openalex.org/W2120434320","https://openalex.org/W2120522615","https://openalex.org/W2121291030","https://openalex.org/W2122869804","https://openalex.org/W2126385616","https://openalex.org/W2126676163","https://openalex.org/W2127827980","https://openalex.org/W2128201302","https://openalex.org/W2128565374","https://openalex.org/W2132811144","https://openalex.org/W2133452708","https://openalex.org/W2140298351","https://openalex.org/W2140402757","https://openalex.org/W2142247182","https://openalex.org/W2143352223","https://openalex.org/W2145371252","https://openalex.org/W2145492845","https://openalex.org/W2147149482","https://openalex.org/W2147231862","https://openalex.org/W2149193660","https://openalex.org/W2152119060","https://openalex.org/W2154705555","https://openalex.org/W2154951298","https://openalex.org/W2156696025","https://openalex.org/W2156877034","https://openalex.org/W2157503003","https://openalex.org/W2160808536","https://openalex.org/W2164868723","https://openalex.org/W2166514496","https://openalex.org/W2166966137","https://openalex.org/W2168909179","https://openalex.org/W2170430546","https://openalex.org/W2170629469","https://openalex.org/W2171118517","https://openalex.org/W2172059940","https://openalex.org/W2401894163","https://openalex.org/W2411113610","https://openalex.org/W2414863658","https://openalex.org/W2417848539","https://openalex.org/W2462051482","https://openalex.org/W2538197248","https://openalex.org/W2559910496","https://openalex.org/W3100080537","https://openalex.org/W3214092816"],"related_works":["https://openalex.org/W7097898521","https://openalex.org/W2096486324","https://openalex.org/W7117973295","https://openalex.org/W3190663391","https://openalex.org/W4235122561","https://openalex.org/W2036187070","https://openalex.org/W2382621607","https://openalex.org/W4286587511","https://openalex.org/W4404794063","https://openalex.org/W7043782244"],"abstract_inverted_index":{"Alzheimer's":[0,71],"disease":[1],"(AD)":[2],"is":[3,10,19,76,114],"the":[4,29,34,42,50,66,83,96,101,111,122,126,130,134,138,148,166,177,187,191,196,233,244,248,264],"most":[5,139,178],"prevalent":[6],"form":[7],"of":[8,45,59,68,89,95,103,133,147,169,189,216,239,260,266],"dementia.AD":[9],"highly":[11],"heritable,":[12],"with":[13],"a":[14,115],"complex":[15],"pattern.Although":[16],"clinical":[17,73],"diagnosis":[18,31,88],"based":[20],"on":[21,33,65,100],"accurate":[22,80],"and":[23,56,86,93,106,119,150,156,182,210,222,224,253],"well":[24,48,227],"defined":[25],"diagnostic":[26],"criteria":[27],"(NINCDS-ADRDA),":[28],"definite":[30],"relies":[32],"postmortem":[35],"pathological":[36],"findings.The":[37],"need":[38,51,77],"for":[39,41,70,78,82,142,164],"measures":[40],"early":[43,84],"detection":[44,85],"AD,":[46],"as":[47,49,226,228],"to":[52,175],"distinguish":[53],"between":[54,243],"AD":[55,261],"other":[57],"forms":[58],"dementia,":[60],"has":[61],"put":[62],"great":[63],"emphasis":[64],"discovery":[67,255],"biomarkers":[69,153,198,254],"disease.In":[72],"practice,":[74],"there":[75],"non-invasive,":[79],"methods":[81],"differential":[87],"AD.The":[90],"successful":[91],"identification":[92],"development":[94],"biomarkers,":[97],"depends":[98],"completely":[99],"understanding":[102],"pathology,":[104],"genetic":[105,149,180,245],"molecular":[107],"mechanisms":[108,235],"involved":[109,236],"in":[110,125,154,186,232,237],"disease.As":[112],"blood":[113,135,152,197,205],"circulating":[116],"dynamic":[117,241],"tissue":[118],"transcription":[120],"reflects":[121],"ongoing":[123],"changes":[124],"system,":[127],"it":[128],"makes":[129],"transcriptional":[131,143],"profiling":[132],"cells,":[136],"potentially,":[137],"sensitive":[140],"source":[141],"biomarkers.A":[144],"systematic":[145],"comparison":[146],"proteomic":[151],"patients":[155],"healthy":[157],"controls":[158],"can":[159,200,256],"reveal":[160],"additional":[161],"potential":[162],"candidates":[163],"AD.In":[165,190],"first":[167],"part":[168],"this":[170],"review,":[171],"we":[172,194],"would":[173],"like":[174],"discuss":[176],"recent":[179],"findings":[181,246],"their":[183,229],"possible":[184,230],"involvement":[185],"pathogenesis":[188,238,262],"second":[192],"part,":[193],"review":[195],"which":[199],"be":[201],"derived":[202],"from":[203],"peripheral":[204],"mononuclear":[206],"cells":[207],"(PBMC),":[208],"serum,":[209],"plasma.We":[211],"discus":[212],"three":[213],"main":[214],"category":[215],"bio-molecules,":[217],"namely":[218],"DNA,":[219],"RNA":[220],"(miRNA":[221],"mRNA),":[223],"protein":[225],"role":[231],"hypothetical":[234],"AD.A":[240],"interaction":[242],"through":[247],"whole":[249],"genome":[250],"association":[251],"studies":[252],"advance":[257],"our":[258],"knowledge":[259],"beyond":[263],"scope":[265],"each":[267],"field":[268],"independently.":[269]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}
