{"id":"https://openalex.org/W2036623444","doi":"https://doi.org/10.1016/j.tet.2006.07.072","title":"On the mechanism of conversion of 4-carboxy-3,4-dihydro-3-phenyl-1(2H)-isoquinolones to indeno[1,2-c]isoquinolines by thionyl chloride","display_name":"On the mechanism of conversion of 4-carboxy-3,4-dihydro-3-phenyl-1(2H)-isoquinolones to indeno[1,2-c]isoquinolines by thionyl chloride","publication_year":2006,"publication_date":"2006-08-22","ids":{"openalex":"https://openalex.org/W2036623444","doi":"https://doi.org/10.1016/j.tet.2006.07.072","mag":"2036623444"},"language":"en","primary_location":{"id":"doi:10.1016/j.tet.2006.07.072","doi":"https://doi.org/10.1016/j.tet.2006.07.072","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.tet.2006.07.072","pdf_url":null,"source":{"id":"https://openalex.org/S205754296","display_name":"Tetrahedron","issn_l":"0040-4020","issn":["0040-4020","1464-5416"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tetrahedron","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5068224926","display_name":"Xiangshu Xiao","orcid":"https://orcid.org/0000-0001-9520-1371","observed_orcids":["https://orcid.org/0000-0001-9520-1371"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]},{"id":"https://openalex.org/I4390039259","display_name":"Purdue University Institute for Cancer Research","ror":"https://ror.org/0371gg960","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039259"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiangshu Xiao","raw_affiliation_strings":["Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue Cancer Center, School of Pharmacy and Pharmaceutical Sciences, Purdue University, West Lafayette, IN 47907, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue Cancer Center, School of Pharmacy and Pharmaceutical Sciences, Purdue University, West Lafayette, IN 47907, USA","institution_ids":["https://openalex.org/I219193219","https://openalex.org/I4390039259"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029783482","display_name":"Andrew E. Morrell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]},{"id":"https://openalex.org/I4390039259","display_name":"Purdue University Institute for Cancer Research","ror":"https://ror.org/0371gg960","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039259"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrew Morrell","raw_affiliation_strings":["Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue Cancer Center, School of Pharmacy and Pharmaceutical Sciences, Purdue University, West Lafayette, IN 47907, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue Cancer Center, School of Pharmacy and Pharmaceutical Sciences, Purdue University, West Lafayette, IN 47907, USA","institution_ids":["https://openalex.org/I219193219","https://openalex.org/I4390039259"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057330382","display_name":"Phillip Edward Fanwick","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Phillip E. Fanwick","raw_affiliation_strings":["Dept. of Chemistry, Purdue University, West Lafayette, IN 47907, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Chemistry, Purdue University, West Lafayette, IN 47907, USA","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025438490","display_name":"Mark Cushman","orcid":"https://orcid.org/0000-0002-0152-5891","observed_orcids":["https://orcid.org/0000-0002-0152-5891"]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]},{"id":"https://openalex.org/I4390039259","display_name":"Purdue University Institute for Cancer Research","ror":"https://ror.org/0371gg960","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4390039259"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Cushman","raw_affiliation_strings":["Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue Cancer Center, School of Pharmacy and Pharmaceutical Sciences, Purdue University, West Lafayette, IN 47907, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicinal Chemistry and Molecular Pharmacology and the Purdue Cancer Center, School of Pharmacy and Pharmaceutical Sciences, Purdue University, West Lafayette, IN 47907, USA","institution_ids":["https://openalex.org/I219193219","https://openalex.org/I4390039259"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3680,"currency":"USD","value_usd":3680},"apc_paid":null,"fwci":0.6326,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.61803916,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"62","issue":"41","first_page":"9705","last_page":"9712"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T14068","display_name":"Organic and Inorganic Chemical Reactions","score":0.28299999237060547,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T14068","display_name":"Organic and Inorganic Chemical Reactions","score":0.28299999237060547,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12191","display_name":"Chemical Reaction Mechanisms","score":0.1234000027179718,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13304","display_name":"Synthesis and Reactivity of Sulfur-Containing Compounds","score":0.11270000040531158,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thionyl-chloride","display_name":"thionyl chloride","score":0.9890000224113464},{"id":"https://openalex.org/keywords/reaction-mechanism","display_name":"reaction mechanism","score":0.8889999985694885},{"id":"https://openalex.org/keywords/friedel-crafts-cyclization","display_name":"Friedel-Crafts cyclization","score":0.9589999914169312},{"id":"https://openalex.org/keywords/heterocycle-synthesis","display_name":"heterocyclic synthesis","score":0.5770000219345093}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9872366786003113},{"id":"https://openalex.org/C2776942435","wikidata":"https://www.wikidata.org/wiki/Q409171","display_name":"Thionyl chloride","level":3,"score":0.9397035837173462},{"id":"https://openalex.org/C89611455","wikidata":"https://www.wikidata.org/wiki/Q6804646","display_name":"Mechanism (biology)","level":2,"score":0.4851852059364319},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.4685799777507782},{"id":"https://openalex.org/C2778695967","wikidata":"https://www.wikidata.org/wiki/Q44791900","display_name":"Chloride","level":2,"score":0.42361193895339966},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.35806936025619507},{"id":"https://openalex.org/C21951064","wikidata":"https://www.wikidata.org/wiki/Q899212","display_name":"Combinatorial chemistry","level":1,"score":0.34240835905075073},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.3282387852668762},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.tet.2006.07.072","doi":"https://doi.org/10.1016/j.tet.2006.07.072","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.tet.2006.07.072","pdf_url":null,"source":{"id":"https://openalex.org/S205754296","display_name":"Tetrahedron","issn_l":"0040-4020","issn":["0040-4020","1464-5416"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tetrahedron","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[{"score":0.47999998927116394,"display_name":"Clean water and sanitation","id":"https://metadata.un.org/sdg/6"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1278281950","display_name":null,"funder_award_id":"C06-14499","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G9000134917","display_name":null,"funder_award_id":"UO1 CA89566","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1976402134","https://openalex.org/W1980059315","https://openalex.org/W1980841314","https://openalex.org/W1987333298","https://openalex.org/W1993643859","https://openalex.org/W1998792067","https://openalex.org/W2002751507","https://openalex.org/W2002992032","https://openalex.org/W2003733678","https://openalex.org/W2013428958","https://openalex.org/W2067064148","https://openalex.org/W2081602756","https://openalex.org/W2083258198","https://openalex.org/W2085294519","https://openalex.org/W2086964996","https://openalex.org/W2088192572","https://openalex.org/W2092078837","https://openalex.org/W2096712606","https://openalex.org/W2124021652","https://openalex.org/W2152195319","https://openalex.org/W2180366699","https://openalex.org/W2316516283","https://openalex.org/W2318895103","https://openalex.org/W2320725613","https://openalex.org/W2329539915","https://openalex.org/W2411740509","https://openalex.org/W2949124839","https://openalex.org/W2950153068","https://openalex.org/W2950208791","https://openalex.org/W2952297079","https://openalex.org/W2952720876","https://openalex.org/W4241881979"],"related_works":["https://openalex.org/W2949966203","https://openalex.org/W2069186452","https://openalex.org/W4251802735","https://openalex.org/W2131445450","https://openalex.org/W2951413373","https://openalex.org/W2029203072","https://openalex.org/W2098615700","https://openalex.org/W2032032873","https://openalex.org/W2122717007","https://openalex.org/W2075937746"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2016-06-24T00:00:00"}