{"id":"https://openalex.org/W2036313652","doi":"https://doi.org/10.1016/j.jalz.2012.05.220","title":"O1\u201004\u201001: Multicentre phase 3 trial on florbetaben for beta\u2010amyloid brain PET in Alzheimer's disease","display_name":"O1\u201004\u201001: Multicentre phase 3 trial on florbetaben for beta\u2010amyloid brain PET in Alzheimer's disease","publication_year":2012,"publication_date":"2012-07-01","ids":{"openalex":"https://openalex.org/W2036313652","doi":"https://doi.org/10.1016/j.jalz.2012.05.220","mag":"2036313652"},"language":"en","primary_location":{"id":"doi:10.1016/j.jalz.2012.05.220","doi":"https://doi.org/10.1016/j.jalz.2012.05.220","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jalz.2012.05.220","pdf_url":null,"source":{"id":"https://openalex.org/S108427512","display_name":"Alzheimer s & Dementia","issn_l":"1552-5260","issn":["1552-5260","1552-5279"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-3","ki-jl-3","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's & Dementia","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088718520","display_name":"Marwan Noel Sabbagh","orcid":"https://orcid.org/0000-0001-8139-3309","observed_orcids":["https://orcid.org/0000-0001-8139-3309"]},"institutions":[{"id":"https://openalex.org/I4210145600","display_name":"Banner Sun Health Research Institute","ror":"https://ror.org/04gjkkf30","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2802412784","https://openalex.org/I4210145600"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marwan Sabbagh","raw_affiliation_strings":["Banner Sun Health Research Institute Sun City Arizona United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Banner Sun Health Research Institute Sun City Arizona United States","institution_ids":["https://openalex.org/I4210145600"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037230816","display_name":"John Peter Seibyl","orcid":"https://orcid.org/0000-0002-4917-5413","observed_orcids":["https://orcid.org/0000-0002-4917-5413"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John Seibyl","raw_affiliation_strings":["MNI Imaging, New Haven, Connecticut, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MNI Imaging, New Haven, Connecticut, United States","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046472539","display_name":"Hiroyasu Akatsu","orcid":"https://orcid.org/0000-0002-0089-6033","observed_orcids":["https://orcid.org/0000-0002-0089-6033"]},"institutions":[{"id":"https://openalex.org/I4210142016","display_name":"Choju Medical Institute","ror":"https://ror.org/044rmp068","country_code":"JP","type":"facility","lineage":["https://openalex.org/I4210142016"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroyasu Akatsu","raw_affiliation_strings":["Choju Medical Institute, Fukushimura, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Choju Medical Institute, Fukushimura, Japan","institution_ids":["https://openalex.org/I4210142016"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089624929","display_name":"Yasoumi Ouchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210163216","display_name":"Hamamatsu Medical Center","ror":"https://ror.org/05vrdt216","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210163216"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yasoumi Ouchi","raw_affiliation_strings":["Hamamatsu Medical Center, Hamamatsu, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Hamamatsu Medical Center, Hamamatsu, Japan","institution_ids":["https://openalex.org/I4210163216"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072613176","display_name":"Thomas G. Beach","orcid":"https://orcid.org/0000-0003-3296-6128","observed_orcids":["https://orcid.org/0000-0003-3296-6128"]},"institutions":[{"id":"https://openalex.org/I4210145600","display_name":"Banner Sun Health Research Institute","ror":"https://ror.org/04gjkkf30","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2802412784","https://openalex.org/I4210145600"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas Beach","raw_affiliation_strings":["Banner Sun Health Research Institute Sun City Arizona United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Banner Sun Health Research Institute Sun City Arizona United States","institution_ids":["https://openalex.org/I4210145600"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088447069","display_name":"Albert Charny","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145600","display_name":"Banner Sun Health Research Institute","ror":"https://ror.org/04gjkkf30","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2802412784","https://openalex.org/I4210145600"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Albert Charny","raw_affiliation_strings":["Banner Sun Health Research Institute Sun City Arizona United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Banner Sun Health Research Institute Sun City Arizona United States","institution_ids":["https://openalex.org/I4210145600"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034480643","display_name":"Henryk Barthel","orcid":"https://orcid.org/0000-0002-9322-9167","observed_orcids":["https://orcid.org/0000-0002-9322-9167"]},"institutions":[{"id":"https://openalex.org/I926574661","display_name":"Leipzig University","ror":"https://ror.org/03s7gtk40","country_code":"DE","type":"education","lineage":["https://openalex.org/I926574661"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Henryk Barthel","raw_affiliation_strings":["University of Leipzig Leipzig Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Leipzig Leipzig Germany","institution_ids":["https://openalex.org/I926574661"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052224169","display_name":"\u5b8f\u5e73 \u4ed9\u7530","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kohei Senda","raw_affiliation_strings":["Kosekei Hospital, Kosekei, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Kosekei Hospital, Kosekei, Japan","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033406675","display_name":"Shigeo Muryama","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405257138","display_name":"Tokyo Metropolitan Hospital Organization","ror":"https://ror.org/04y0s1771","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405257138"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shigeo Muryama","raw_affiliation_strings":["Tokyo Metropolitan Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tokyo Metropolitan Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4405257138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5149174020","display_name":"Kenji Ishii","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405257138","display_name":"Tokyo Metropolitan Hospital Organization","ror":"https://ror.org/04y0s1771","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4405257138"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kenji Iishi","raw_affiliation_strings":["Tokyo Metropolitan Hospital, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tokyo Metropolitan Hospital, Tokyo, Japan","institution_ids":["https://openalex.org/I4405257138"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052130722","display_name":"James B. Leverenz","orcid":"https://orcid.org/0000-0002-0896-0749","observed_orcids":["https://orcid.org/0000-0002-0896-0749"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Leverenz","raw_affiliation_strings":["University of Washington Seattle Washington United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Washington Seattle Washington United States","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047929315","display_name":"Bernardino Francesco Ghetti","orcid":"https://orcid.org/0000-0002-1842-8019","observed_orcids":["https://orcid.org/0000-0002-1842-8019"]},"institutions":[{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bernardino Ghetti","raw_affiliation_strings":["Indiana University School of Medicine, Indianapolis, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Indiana University School of Medicine, Indianapolis, United States","institution_ids":["https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002436634","display_name":"James W. Ironside","orcid":"https://orcid.org/0000-0001-5869-2108","observed_orcids":["https://orcid.org/0000-0001-5869-2108"]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"James Ironside","raw_affiliation_strings":["University of Edinburgh, edinburgh, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Edinburgh, edinburgh, United Kingdom","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Katrin Roth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I67348948","display_name":"Bayer (Germany)","ror":"https://ror.org/04hmn8g73","country_code":"DE","type":"company","lineage":["https://openalex.org/I67348948"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Katrin Roth","raw_affiliation_strings":["Bayer Health Care, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bayer Health Care, Berlin, Germany","institution_ids":["https://openalex.org/I67348948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021057144","display_name":"Anja Hoffmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I67348948","display_name":"Bayer (Germany)","ror":"https://ror.org/04hmn8g73","country_code":"DE","type":"company","lineage":["https://openalex.org/I67348948"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Anja Hoffmann","raw_affiliation_strings":["Bayer Health Care, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bayer Health Care, Berlin, Germany","institution_ids":["https://openalex.org/I67348948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066508131","display_name":"Walter Schulz\u2010Schaeffer","orcid":"https://orcid.org/0000-0001-5886-2322","observed_orcids":["https://orcid.org/0000-0001-5886-2322"]},"institutions":[{"id":"https://openalex.org/I74656192","display_name":"University of G\u00f6ttingen","ror":"https://ror.org/01y9bpm73","country_code":"DE","type":"education","lineage":["https://openalex.org/I74656192"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Walter Schulz\u2010Schaeffer","raw_affiliation_strings":["(Georg August University of Goettingen, Goettingen, Germany)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"(Georg August University of Goettingen, Goettingen, Germany)","institution_ids":["https://openalex.org/I74656192"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078183953","display_name":"Cornelia B Reininger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I67348948","display_name":"Bayer (Germany)","ror":"https://ror.org/04hmn8g73","country_code":"DE","type":"company","lineage":["https://openalex.org/I67348948"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Cornelia Reininger","raw_affiliation_strings":["Bayer Health Care, Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Bayer Health Care, Berlin, Germany","institution_ids":["https://openalex.org/I67348948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008894116","display_name":"Osama Sabri","orcid":"https://orcid.org/0000-0002-6425-3504","observed_orcids":["https://orcid.org/0000-0002-6425-3504"]},"institutions":[{"id":"https://openalex.org/I926574661","display_name":"Leipzig University","ror":"https://ror.org/03s7gtk40","country_code":"DE","type":"education","lineage":["https://openalex.org/I926574661"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Osama Sabri","raw_affiliation_strings":["University of Leipzig Leipzig Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Leipzig Leipzig Germany","institution_ids":["https://openalex.org/I926574661"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":10,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4200,"currency":"USD","value_usd":4200},"apc_paid":null,"fwci":1.2985,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.78394903,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"8","issue":"4S_Part_3","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.8881999850273132,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.8881999850273132,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.10599999874830246,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10522","display_name":"Medical Imaging Techniques and Applications","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/florbetaben","display_name":"florbetaben","score":0.9940000176429749},{"id":"https://openalex.org/keywords/amyloid-beta","display_name":"amyloid-beta","score":0.675000011920929}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.670795738697052},{"id":"https://openalex.org/C2777633098","wikidata":"https://www.wikidata.org/wiki/Q2736051","display_name":"Amyloid (mycology)","level":2,"score":0.5487549304962158},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.5311397910118103},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4934960603713989},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.45510944724082947},{"id":"https://openalex.org/C2776156579","wikidata":"https://www.wikidata.org/wiki/Q417667","display_name":"Amyloid beta","level":3,"score":0.42975562810897827},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.3541664779186249},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09900343418121338},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jalz.2012.05.220","doi":"https://doi.org/10.1016/j.jalz.2012.05.220","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jalz.2012.05.220","pdf_url":null,"source":{"id":"https://openalex.org/S108427512","display_name":"Alzheimer s & Dementia","issn_l":"1552-5260","issn":["1552-5260","1552-5279"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-3","ki-jl-3","medline","norway-1","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alzheimer's & Dementia","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2169508236","https://openalex.org/W2600315017","https://openalex.org/W2328020202","https://openalex.org/W2150496641","https://openalex.org/W2146187326","https://openalex.org/W2044658778","https://openalex.org/W1647378451","https://openalex.org/W2171682279","https://openalex.org/W2081780192","https://openalex.org/W7098507411"],"abstract_inverted_index":{"Validation":[0],"of":[1,9,33,55,91,111,134,146,157,183,188,250,264,269,275],"florbetaben":[2,39,177,214,280],"PET":[3,16,40,215,270],"as":[4,305],"a":[5,66,75,81,143,181,186,223,247,293,301,306],"diagnostic":[6],"imaging":[7,154],"biomarker":[8,307],"Alzheimer":[10],"disease":[11],"requires":[12],"comparison":[13,176,199],"between":[14],"brain":[15,100,221,257,289],"and":[17,38,73,127,129,153,170,185,200,234,259,296,298],"post":[18,164,254],"mortem":[19,165,255],"tissue.":[20],"238":[21],"end-of-life":[22],"patients":[23],"were":[24,45,94],"recruited":[25],"from":[26],"17":[27],"centers":[28],"across":[29],"4":[30],"continents.":[31],"204":[32],"these":[34],"individuals":[35,44],"underwent":[36],"MRI":[37],"scanning.":[41],"10":[42],"healthy":[43],"also":[46],"included":[47,95],"to":[48,106,150,243,283],"support":[49],"specificity.":[50,172,236],"Cortical":[51],"presence":[52,131,266],"or":[53,132,267],"absence":[54,133,268],"tracer":[56,271],"uptake":[57],"was":[58,102,123,140,193],"determined":[59,141],"by":[60,125,142],"3":[61,147,210],"independent":[62],"blinded":[63,149],"readers":[64],"on":[65,74],"regional":[67,175,204],"basis":[68],"for":[69,86,108,195,202,228,308],"6":[70],"pre-specified":[71],"regions":[72,139],"subject":[76,159,197],"level":[77,160,198],"taking":[78],"into":[79],"account":[80],"visual":[82,224],"scoring":[83,225],"method":[84,226],"proposed":[85,227],"clinical":[87,152,229],"practice.":[88],"A":[89],"total":[90],"31":[92],"brains":[93],"in":[96,104,120,136,219,253,287],"the":[97,112,116,121,130,137,158,163,174,196,203,220,240,265,288],"analysis.":[98],"The":[99,190,273],"autopsy":[101],"photo-documented":[103],"detail":[105],"allow":[107],"precise":[109,248],"alignment":[110],"tissue":[113,122],"samples":[114],"with":[115,162,180,231,292],"MRI/PET":[117],"images.":[118],"b-amyloid":[119,135,179,218,251],"detected":[124,178],"silver-staining":[126],"immunohistochemistry":[128],"cortical":[138,256],"consensus":[144],"panel":[145],"neuropathologists":[148],"all":[151],"data.":[155],"Comparison":[156],"analysis":[161],"diagnosis":[166],"yielded":[167],"100%":[168,232],"sensitivity":[169,182,233,295],"92%":[171,235],"For":[173],"77%":[184],"specificity":[187,297],"94%.":[189],"inter-reader":[191],"agreement":[192],"0.87":[194],"0.66":[201],"assessment,":[205],"respectively.":[206],"This":[207],"global":[208],"phase":[209],"trial":[211,277],"confirmed":[212],"that":[213,279],"can":[216],"detect":[217,284],"using":[222],"practice":[230],"Moreover,":[237],"this":[238,276,309],"is":[239,281,300],"first":[241],"study":[242],"have":[244],"undergone:":[245],"1)":[246],"determination":[249,263],"status":[252],"tissue,":[258],"an":[260],"2)":[261],"exact":[262],"uptake.":[272],"results":[274],"confirm":[278],"able":[282],"b":[285],"-amyloid":[286],"during":[290],"life":[291],"high":[294],"thus,":[299],"more":[302],"than":[303],"suitable":[304],"purpose.":[310]},"counts_by_year":[{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}