{"id":"https://openalex.org/W2035975952","doi":"https://doi.org/10.1248/bpb.28.1672","title":"Isolation of a Human Intestinal Bacterium That Transforms Mangiferin to Norathyriol and Inducibility of the Enzyme That Cleaves a C-Glucosyl Bond","display_name":"Isolation of a Human Intestinal Bacterium That Transforms Mangiferin to Norathyriol and Inducibility of the Enzyme That Cleaves a C-Glucosyl Bond","publication_year":2005,"publication_date":"2005-01-01","ids":{"openalex":"https://openalex.org/W2035975952","doi":"https://doi.org/10.1248/bpb.28.1672","mag":"2035975952","pmid":"https://pubmed.ncbi.nlm.nih.gov/16141538"},"language":"en","primary_location":{"id":"doi:10.1248/bpb.28.1672","doi":"https://doi.org/10.1248/bpb.28.1672","is_oa":true,"landing_page_url":"https://doi.org/10.1248/bpb.28.1672","pdf_url":"https://www.jstage.jst.go.jp/article/bpb/28/9/28_9_1672/_pdf","source":{"id":"https://openalex.org/S165235614","display_name":"Biological and Pharmaceutical Bulletin","issn_l":"0918-6158","issn":["0918-6158","1347-5215"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313382","host_organization_name":"Pharmaceutical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313382"],"host_organization_lineage_names":["Pharmaceutical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological and Pharmaceutical Bulletin","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.jstage.jst.go.jp/article/bpb/28/9/28_9_1672/_pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036754506","display_name":"Kanjana Sanugul","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I42766147","display_name":"University of Toyama","ror":"https://ror.org/0445phv87","country_code":"JP","type":"education","lineage":["https://openalex.org/I42766147"]},{"id":"https://openalex.org/I4405287106","display_name":"Institute of Natural Medicine, University of Toyama","ror":"https://ror.org/0449t5597","country_code":"JP","type":"facility","lineage":["https://openalex.org/I42766147","https://openalex.org/I4405287106"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kanjana Sanugul","raw_affiliation_strings":["Institute of Natural Medicine, Toyama Medical and Pharmaceutical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Natural Medicine, Toyama Medical and Pharmaceutical University","institution_ids":["https://openalex.org/I42766147","https://openalex.org/I4405287106"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109298012","display_name":"Teruaki Akao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I42766147","display_name":"University of Toyama","ror":"https://ror.org/0445phv87","country_code":"JP","type":"education","lineage":["https://openalex.org/I42766147"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Teruaki Akao","raw_affiliation_strings":["Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Pharmaceutical Sciences, Toyama Medical and Pharmaceutical University","institution_ids":["https://openalex.org/I42766147"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100342556","display_name":"Yan Li","orcid":"https://orcid.org/0009-0008-4182-8265","observed_orcids":["https://orcid.org/0009-0008-4182-8265"]},"institutions":[{"id":"https://openalex.org/I42766147","display_name":"University of Toyama","ror":"https://ror.org/0445phv87","country_code":"JP","type":"education","lineage":["https://openalex.org/I42766147"]},{"id":"https://openalex.org/I4405287106","display_name":"Institute of Natural Medicine, University of Toyama","ror":"https://ror.org/0449t5597","country_code":"JP","type":"facility","lineage":["https://openalex.org/I42766147","https://openalex.org/I4405287106"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Yan Li","raw_affiliation_strings":["Institute of Natural Medicine, Toyama Medical and Pharmaceutical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Natural Medicine, Toyama Medical and Pharmaceutical University","institution_ids":["https://openalex.org/I42766147","https://openalex.org/I4405287106"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065115698","display_name":"Nobuko Kakiuchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I10091056","display_name":"Kanazawa University","ror":"https://ror.org/02hwp6a56","country_code":"JP","type":"education","lineage":["https://openalex.org/I10091056"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobuko Kakiuchi","raw_affiliation_strings":["Graduate School of Natural Science and Technology, Kanazawa University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Graduate School of Natural Science and Technology, Kanazawa University","institution_ids":["https://openalex.org/I10091056"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101399477","display_name":"Norio Nakamura","orcid":"https://orcid.org/0000-0001-6740-5633","observed_orcids":["https://orcid.org/0000-0001-6740-5633"]},"institutions":[{"id":"https://openalex.org/I42766147","display_name":"University of Toyama","ror":"https://ror.org/0445phv87","country_code":"JP","type":"education","lineage":["https://openalex.org/I42766147"]},{"id":"https://openalex.org/I4405287106","display_name":"Institute of Natural Medicine, University of Toyama","ror":"https://ror.org/0449t5597","country_code":"JP","type":"facility","lineage":["https://openalex.org/I42766147","https://openalex.org/I4405287106"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Norio Nakamura","raw_affiliation_strings":["Institute of Natural Medicine, Toyama Medical and Pharmaceutical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Natural Medicine, Toyama Medical and Pharmaceutical University","institution_ids":["https://openalex.org/I42766147","https://openalex.org/I4405287106"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103499657","display_name":"Masao Hattori","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I42766147","display_name":"University of Toyama","ror":"https://ror.org/0445phv87","country_code":"JP","type":"education","lineage":["https://openalex.org/I42766147"]},{"id":"https://openalex.org/I4405287106","display_name":"Institute of Natural Medicine, University of Toyama","ror":"https://ror.org/0449t5597","country_code":"JP","type":"facility","lineage":["https://openalex.org/I42766147","https://openalex.org/I4405287106"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masao Hattori","raw_affiliation_strings":["Institute of Natural Medicine, Toyama Medical and Pharmaceutical University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Natural Medicine, Toyama Medical and Pharmaceutical University","institution_ids":["https://openalex.org/I42766147","https://openalex.org/I4405287106"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":8.8602,"has_fulltext":true,"cited_by_count":98,"citation_normalized_percentile":{"value":0.96575938,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"28","issue":"9","first_page":"1672","last_page":"1678"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13846","display_name":"Mangiferin and Mango Extracts","score":0.9785000085830688,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13846","display_name":"Mangiferin and Mango Extracts","score":0.9785000085830688,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mangiferin","display_name":"mangiferin","score":0.996999979019165},{"id":"https://openalex.org/keywords/norathyriol","display_name":"norathyriol","score":0.9800000190734863},{"id":"https://openalex.org/keywords/c-glucosides","display_name":"C-glucosides","score":0.7950000166893005},{"id":"https://openalex.org/keywords/bacteroides","display_name":"Bacteroides","score":0.8149999976158142},{"id":"https://openalex.org/keywords/human-intestinal-bacteria","display_name":"human intestinal bacteria","score":0.8960000276565552},{"id":"https://openalex.org/keywords/fecal-bacteria","display_name":"fecal bacteria","score":0.5339999794960022},{"id":"https://openalex.org/keywords/enzyme-induction","display_name":"enzyme induction","score":0.6959999799728394},{"id":"https://openalex.org/keywords/1-deoxynojirimycin","display_name":"1-deoxynojirimycin","score":0.75},{"id":"https://openalex.org/keywords/gluconolactone","display_name":"gluconolactone","score":0.9120000004768372},{"id":"https://openalex.org/keywords/glucosidase-inhibitors","display_name":"glucosidase inhibitors","score":0.7649999856948853},{"id":"https://openalex.org/keywords/rifampicin","display_name":"rifampicin","score":0.7369999885559082},{"id":"https://openalex.org/keywords/chloramphenicol","display_name":"chloramphenicol","score":0.9440000057220459},{"id":"https://openalex.org/keywords/drug-metabolism","display_name":"drug metabolism","score":0.3009999990463257}],"concepts":[{"id":"https://openalex.org/C2777781930","wikidata":"https://www.wikidata.org/wiki/Q1074417","display_name":"Mangiferin","level":2,"score":0.9251207113265991},{"id":"https://openalex.org/C2779396346","wikidata":"https://www.wikidata.org/wiki/Q394316","display_name":"Aglycone","level":3,"score":0.7679929733276367},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.6878372430801392},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.6658151149749756},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6602838039398193},{"id":"https://openalex.org/C2775842281","wikidata":"https://www.wikidata.org/wiki/Q421789","display_name":"Xanthone","level":2,"score":0.6433266401290894},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5960180759429932},{"id":"https://openalex.org/C2778168646","wikidata":"https://www.wikidata.org/wiki/Q133186","display_name":"Bacteroides","level":3,"score":0.4542442560195923},{"id":"https://openalex.org/C196032511","wikidata":"https://www.wikidata.org/wiki/Q375795","display_name":"Glycoside hydrolase","level":3,"score":0.44817814230918884},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.4447515308856964},{"id":"https://openalex.org/C175156509","wikidata":"https://www.wikidata.org/wiki/Q1990218","display_name":"Cleavage (geology)","level":3,"score":0.4395739436149597},{"id":"https://openalex.org/C3044715","wikidata":"https://www.wikidata.org/wiki/Q3952437","display_name":"Bond cleavage","level":3,"score":0.4252203702926636},{"id":"https://openalex.org/C194671627","wikidata":"https://www.wikidata.org/wiki/Q192639","display_name":"Glycoside","level":2,"score":0.32435035705566406},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2552995979785919},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.06482088565826416},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C43369102","wikidata":"https://www.wikidata.org/wiki/Q2307625","display_name":"Fracture (geology)","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002855","descriptor_name":"Chromatography, Thin Layer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003470","descriptor_name":"Culture Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004790","descriptor_name":"Enzyme Induction","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005959","descriptor_name":"Glucosidases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007422","descriptor_name":"Intestines","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D012329","descriptor_name":"RNA, Bacterial","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D012329","descriptor_name":"RNA, Bacterial","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012336","descriptor_name":"RNA, Ribosomal, 16S","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014966","descriptor_name":"Xanthenes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D044004","descriptor_name":"Xanthones","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1248/bpb.28.1672","doi":"https://doi.org/10.1248/bpb.28.1672","is_oa":true,"landing_page_url":"https://doi.org/10.1248/bpb.28.1672","pdf_url":"https://www.jstage.jst.go.jp/article/bpb/28/9/28_9_1672/_pdf","source":{"id":"https://openalex.org/S165235614","display_name":"Biological and Pharmaceutical Bulletin","issn_l":"0918-6158","issn":["0918-6158","1347-5215"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313382","host_organization_name":"Pharmaceutical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313382"],"host_organization_lineage_names":["Pharmaceutical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological and Pharmaceutical Bulletin","raw_type":"journal-article"},{"id":"pmid:16141538","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16141538","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological & pharmaceutical bulletin","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1248/bpb.28.1672","doi":"https://doi.org/10.1248/bpb.28.1672","is_oa":true,"landing_page_url":"https://doi.org/10.1248/bpb.28.1672","pdf_url":"https://www.jstage.jst.go.jp/article/bpb/28/9/28_9_1672/_pdf","source":{"id":"https://openalex.org/S165235614","display_name":"Biological and Pharmaceutical Bulletin","issn_l":"0918-6158","issn":["0918-6158","1347-5215"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310313382","host_organization_name":"Pharmaceutical Society of Japan","host_organization_lineage":["https://openalex.org/P4310313382"],"host_organization_lineage_names":["Pharmaceutical Society of Japan"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological and Pharmaceutical Bulletin","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2035975952.pdf","grobid_xml":"https://content.openalex.org/works/W2035975952.grobid-xml"},"referenced_works_count":35,"referenced_works":["https://openalex.org/W1491853105","https://openalex.org/W1503244037","https://openalex.org/W1525811070","https://openalex.org/W1533313469","https://openalex.org/W1539429578","https://openalex.org/W1549910821","https://openalex.org/W1566830427","https://openalex.org/W1963997725","https://openalex.org/W1967766284","https://openalex.org/W1972414582","https://openalex.org/W1982161177","https://openalex.org/W1992763603","https://openalex.org/W1998779387","https://openalex.org/W2008422627","https://openalex.org/W2013530423","https://openalex.org/W2016081462","https://openalex.org/W2023900268","https://openalex.org/W2038795936","https://openalex.org/W2042400082","https://openalex.org/W2043685355","https://openalex.org/W2055594026","https://openalex.org/W2062449122","https://openalex.org/W2067663424","https://openalex.org/W2075603878","https://openalex.org/W2078964661","https://openalex.org/W2088617671","https://openalex.org/W2090745121","https://openalex.org/W2152092250","https://openalex.org/W2163184793","https://openalex.org/W2333855215","https://openalex.org/W2468825568","https://openalex.org/W2951986005","https://openalex.org/W3023773984","https://openalex.org/W3142525956","https://openalex.org/W4205634428"],"related_works":["https://openalex.org/W2288700551","https://openalex.org/W2023993862","https://openalex.org/W2038795936","https://openalex.org/W3125321366","https://openalex.org/W2998814955","https://openalex.org/W3041398674","https://openalex.org/W1496642049","https://openalex.org/W2320336531","https://openalex.org/W3173360087","https://openalex.org/W4408059680"],"abstract_inverted_index":{"The":[0,40,119],"C-glucosyl":[1,31,56,63,100],"bond":[2],"of":[3,28,36,54,76,83,153,164],"C-glucosides":[4,12],"generally":[5],"tolerates":[6],"acid":[7],"and":[8,67,85,91,113,134,166,171],"enzymatic":[9],"hydrolysis.":[10],"Many":[11],"are":[13],"cleaved":[14,62],"by":[15,81,103,127],"human":[16,37],"intestinal":[17,156],"bacteria.":[18,39],"We":[19],"isolated":[20],"the":[21,26,49,74,96,137,150,162],"specific":[22,155],"bacterium":[23,157],"involved":[24,160],"in":[25,64,73,121,161],"metabolism":[27,163],"mangiferin":[29,47,107,165],"(2-beta-D-glucopyranosyl-1,3,6,7-tetrahydroxyxanthone),":[30],"xanthone,":[32],"from":[33,142],"a":[34,55,65,154,169],"mixture":[35],"fecal":[38],"anaerobic":[41],"Bacteroides":[42],"species":[43],"named":[44],"MANG,":[45],"transformed":[46],"to":[48],"aglycone,":[50],"norathyriol,":[51],"suggesting":[52],"cleavage":[53],"bond.":[57],"However,":[58],"B.":[59],"sp.":[60],"MANG":[61],"dose-":[66],"time-dependent":[68],"manner":[69],"only":[70],"when":[71],"cultivated":[72],"presence":[75],"mangiferin.":[77,104],"Cleavage":[78],"was":[79,124],"abolished":[80],"inhibitors":[82,130],"RNA":[84],"protein":[86],"syntheses,":[87],"such":[88,131],"as":[89,132],"rifampicin":[90],"chloramphenicol,":[92],"respectively,":[93],"indicating":[94],"that":[95,98,145,158],"enzyme":[97,139],"cleaves":[99],"is":[101,149,159],"induced":[102],"In":[105],"contrast,":[106],"did":[108],"not":[109,125],"affect":[110],"bacterial":[111],"alpha-":[112],"beta-glucosidase":[114],"activities":[115],"under":[116],"any":[117],"conditions.":[118],"C-glucosyl-cleavage":[120],"cell-free":[122],"extracts":[123],"altered":[126],"potent":[128],"glucosidase":[129],"1-deoxynojirimycin":[133],"gluconolactone.":[135],"Therefore,":[136],"C-glucosyl-cleaving":[138,173],"substantially":[140],"differs":[141],"known":[143],"glucosidases":[144],"cleave":[146],"O-glucosides.":[147],"This":[148],"first":[151],"description":[152],"which":[167],"produces":[168],"novel":[170],"inducible":[172],"enzyme.":[174]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":8},{"year":2018,"cited_by_count":8},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":6},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2016-06-24T00:00:00"}