{"id":"https://openalex.org/W2035804164","doi":"https://doi.org/10.1016/0167-4838(94)90009-4","title":"\u03b1-Crystallin: molecular chaperone and protein surfactant","display_name":"\u03b1-Crystallin: molecular chaperone and protein surfactant","publication_year":1994,"publication_date":"1994-02-01","ids":{"openalex":"https://openalex.org/W2035804164","doi":"https://doi.org/10.1016/0167-4838(94)90009-4","mag":"2035804164","pmid":"https://pubmed.ncbi.nlm.nih.gov/8142460"},"language":"en","primary_location":{"id":"doi:10.1016/0167-4838(94)90009-4","doi":"https://doi.org/10.1016/0167-4838(94)90009-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0167-4838(94)90009-4","pdf_url":null,"source":{"id":"https://openalex.org/S4394735818","display_name":"Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology","issn_l":"0167-4838","issn":["0167-4838","1879-2588"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033863920","display_name":"John A. Carver","orcid":"https://orcid.org/0000-0002-2441-8108","observed_orcids":["https://orcid.org/0000-0002-2441-8108"]},"institutions":[{"id":"https://openalex.org/I204824540","display_name":"University of Wollongong","ror":"https://ror.org/00jtmb277","country_code":"AU","type":"education","lineage":["https://openalex.org/I204824540"]}],"countries":["AU"],"is_corresponding":true,"raw_author_name":"John A. Carver","raw_affiliation_strings":["Australian Cataract Research Foundation, Department of Chemistry, University of Wollongong, NSW"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Australian Cataract Research Foundation, Department of Chemistry, University of Wollongong, NSW","institution_ids":["https://openalex.org/I204824540"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030294692","display_name":"J. Andrew Aquilina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204824540","display_name":"University of Wollongong","ror":"https://ror.org/00jtmb277","country_code":"AU","type":"education","lineage":["https://openalex.org/I204824540"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"J.Andrew Aquilina","raw_affiliation_strings":["Australian Cataract Research Foundation, Department of Chemistry, The University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Australian Cataract Research Foundation, Department of Chemistry, The University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia","institution_ids":["https://openalex.org/I204824540"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074638107","display_name":"Philip G. Cooper","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204824540","display_name":"University of Wollongong","ror":"https://ror.org/00jtmb277","country_code":"AU","type":"education","lineage":["https://openalex.org/I204824540"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Philip G. Cooper","raw_affiliation_strings":["Australian Cataract Research Foundation, Department of Chemistry, The University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Australian Cataract Research Foundation, Department of Chemistry, The University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia","institution_ids":["https://openalex.org/I204824540"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111538131","display_name":"G Williams","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204824540","display_name":"University of Wollongong","ror":"https://ror.org/00jtmb277","country_code":"AU","type":"education","lineage":["https://openalex.org/I204824540"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Gavin A. Williams","raw_affiliation_strings":["Australian Cataract Research Foundation, Department of Chemistry, The University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Australian Cataract Research Foundation, Department of Chemistry, The University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia","institution_ids":["https://openalex.org/I204824540"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110058663","display_name":"Roger J.W. Truscott","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204824540","display_name":"University of Wollongong","ror":"https://ror.org/00jtmb277","country_code":"AU","type":"education","lineage":["https://openalex.org/I204824540"]}],"countries":["AU"],"is_corresponding":false,"raw_author_name":"Roger J.W. Truscott","raw_affiliation_strings":["Australian Cataract Research Foundation, Department of Chemistry, The University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Australian Cataract Research Foundation, Department of Chemistry, The University of Wollongong, Northfields Avenue, Wollongong, NSW 2522, Australia","institution_ids":["https://openalex.org/I204824540"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5033863920"],"corresponding_institution_ids":["https://openalex.org/I204824540"],"apc_list":null,"apc_paid":null,"fwci":2.6407,"has_fulltext":false,"cited_by_count":83,"citation_normalized_percentile":{"value":0.91171077,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"1204","issue":"2","first_page":"195","last_page":"206"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/molecular-chaperones","display_name":"molecular chaperones","score":0.953000009059906},{"id":"https://openalex.org/keywords/protein-stabilization","display_name":"protein stabilization","score":0.7749999761581421},{"id":"https://openalex.org/keywords/thermal-denaturation","display_name":"thermal denaturation","score":0.8050000071525574},{"id":"https://openalex.org/keywords/protein-surfactants","display_name":"protein surfactants","score":0.7440000176429749},{"id":"https://openalex.org/keywords/critical-micelle-concentration","display_name":"critical micelle concentration","score":0.972000002861023},{"id":"https://openalex.org/keywords/protein-aggregation","display_name":"protein aggregation","score":0.6620000004768372},{"id":"https://openalex.org/keywords/alcohol-dehydrogenase","display_name":"alcohol dehydrogenase","score":0.8880000114440918},{"id":"https://openalex.org/keywords/gamma-crystallin","display_name":"gamma-crystallin","score":0.9729999899864197},{"id":"https://openalex.org/keywords/hydrophobic-interactions","display_name":"hydrophobic interactions","score":0.8730000257492065},{"id":"https://openalex.org/keywords/protein-protein-interaction","display_name":"protein-protein interaction","score":0.7179999947547913},{"id":"https://openalex.org/keywords/lens-proteins","display_name":"lens proteins","score":0.652999997138977},{"id":"https://openalex.org/keywords/protein-precipitation","display_name":"protein precipitation","score":0.37299999594688416},{"id":"https://openalex.org/keywords/anionic-surfactants","display_name":"anionic surfactants","score":0.656000018119812}],"concepts":[{"id":"https://openalex.org/C7263354","wikidata":"https://www.wikidata.org/wiki/Q2992167","display_name":"Crystallin","level":2,"score":0.8969120979309082},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7497097253799438},{"id":"https://openalex.org/C166940927","wikidata":"https://www.wikidata.org/wiki/Q178827","display_name":"Monomer","level":3,"score":0.6246387958526611},{"id":"https://openalex.org/C58226133","wikidata":"https://www.wikidata.org/wiki/Q1324199","display_name":"Pulmonary surfactant","level":2,"score":0.5785477161407471},{"id":"https://openalex.org/C11268172","wikidata":"https://www.wikidata.org/wiki/Q421110","display_name":"Micelle","level":3,"score":0.4864670932292938},{"id":"https://openalex.org/C102931765","wikidata":"https://www.wikidata.org/wiki/Q189673","display_name":"Dissociation (chemistry)","level":2,"score":0.46593350172042847},{"id":"https://openalex.org/C2780642029","wikidata":"https://www.wikidata.org/wiki/Q726004","display_name":"Oligomer","level":2,"score":0.4423930048942566},{"id":"https://openalex.org/C64237528","wikidata":"https://www.wikidata.org/wiki/Q607000","display_name":"Critical micelle concentration","level":4,"score":0.41884687542915344},{"id":"https://openalex.org/C2776923230","wikidata":"https://www.wikidata.org/wiki/Q16955798","display_name":"Denaturation (fissile materials)","level":2,"score":0.4113849699497223},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.4053797721862793},{"id":"https://openalex.org/C8010536","wikidata":"https://www.wikidata.org/wiki/Q160398","display_name":"Crystallography","level":1,"score":0.3726659417152405},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3303494453430176},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.2501124143600464},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1908901035785675},{"id":"https://openalex.org/C184651966","wikidata":"https://www.wikidata.org/wiki/Q906356","display_name":"Aqueous solution","level":2,"score":0.12184259295463562},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.11685985326766968},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000426","descriptor_name":"Alcohol Dehydrogenase","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002845","descriptor_name":"Chromatography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003459","descriptor_name":"Crystallins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D004553","descriptor_name":"Electric Conductivity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006358","descriptor_name":"Hot Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009682","descriptor_name":"Magnetic Resonance Spectroscopy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013053","descriptor_name":"Spectrophotometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013499","descriptor_name":"Surface Properties","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0167-4838(94)90009-4","doi":"https://doi.org/10.1016/0167-4838(94)90009-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0167-4838(94)90009-4","pdf_url":null,"source":{"id":"https://openalex.org/S4394735818","display_name":"Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology","issn_l":"0167-4838","issn":["0167-4838","1879-2588"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["norway-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology","raw_type":"journal-article"},{"id":"pmid:8142460","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8142460","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochimica et biophysica acta","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320334705","display_name":"National Health and Medical Research Council","ror":"https://ror.org/011kf5r70"},{"id":"https://openalex.org/F4320334737","display_name":"National Medical Research Council","ror":"https://ror.org/04x3cxs03"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":36,"referenced_works":["https://openalex.org/W151404467","https://openalex.org/W592303347","https://openalex.org/W1486292873","https://openalex.org/W1491094771","https://openalex.org/W1497843695","https://openalex.org/W1520938646","https://openalex.org/W1546160251","https://openalex.org/W1574225286","https://openalex.org/W1662998834","https://openalex.org/W1671787304","https://openalex.org/W1963875432","https://openalex.org/W1968802798","https://openalex.org/W1976495962","https://openalex.org/W1977537170","https://openalex.org/W1978302916","https://openalex.org/W1985515623","https://openalex.org/W1988485119","https://openalex.org/W1989675515","https://openalex.org/W2002365379","https://openalex.org/W2010270200","https://openalex.org/W2018464489","https://openalex.org/W2020332937","https://openalex.org/W2025388082","https://openalex.org/W2025813076","https://openalex.org/W2033597620","https://openalex.org/W2052092359","https://openalex.org/W2054045116","https://openalex.org/W2071308786","https://openalex.org/W2071652326","https://openalex.org/W2090738882","https://openalex.org/W2093329753","https://openalex.org/W2130224280","https://openalex.org/W2144001142","https://openalex.org/W2735357078","https://openalex.org/W4205090231","https://openalex.org/W4236257311"],"related_works":["https://openalex.org/W1564205457","https://openalex.org/W2092457909","https://openalex.org/W2290403944","https://openalex.org/W1994451280","https://openalex.org/W1517238059","https://openalex.org/W2462870744","https://openalex.org/W2160380154","https://openalex.org/W1599376419","https://openalex.org/W4243657778","https://openalex.org/W2057294351"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}