{"id":"https://openalex.org/W2035456780","doi":"https://doi.org/10.1097/00007632-199809010-00020","title":"Lumbar Intervertebral Disc Involvement in Chronic Lymphocytic Leukemia","display_name":"Lumbar Intervertebral Disc Involvement in Chronic Lymphocytic Leukemia","publication_year":1998,"publication_date":"1998-09-01","ids":{"openalex":"https://openalex.org/W2035456780","doi":"https://doi.org/10.1097/00007632-199809010-00020","mag":"2035456780","pmid":"https://pubmed.ncbi.nlm.nih.gov/9762748"},"language":"en","primary_location":{"id":"doi:10.1097/00007632-199809010-00020","doi":"https://doi.org/10.1097/00007632-199809010-00020","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00007632-199809010-00020","pdf_url":null,"source":{"id":"https://openalex.org/S4026894","display_name":"Spine","issn_l":"0362-2436","issn":["0362-2436","1528-1159"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Spine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109109001","display_name":"Timothy U. Jiya","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Timothy U. Jiya","raw_affiliation_strings":["Department of Orthopaedic Surgery, Free University Hospital, Amsterdam, The Netherlands","Orthopaedic Surgery, \u2020Pathology, and \u2021Radiology, Free University Hospital, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Free University Hospital, Amsterdam, The Netherlands","institution_ids":[]},{"raw_affiliation_string":"Orthopaedic Surgery, \u2020Pathology, and \u2021Radiology, Free University Hospital, Amsterdam, The Netherlands","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049464780","display_name":"Barend J. van Royen","orcid":"https://orcid.org/0000-0002-6548-7214","observed_orcids":["https://orcid.org/0000-0002-6548-7214"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Barend J. Van Royen","raw_affiliation_strings":["Orthopaedic Surgery, \u2020Pathology, and \u2021Radiology, Free University Hospital, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopaedic Surgery, \u2020Pathology, and \u2021Radiology, Free University Hospital, Amsterdam, The Netherlands","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080912741","display_name":"Shinsuke Sugihara","orcid":"https://orcid.org/0000-0002-9460-3982","observed_orcids":["https://orcid.org/0000-0002-9460-3982"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Shinsuke Sugihara","raw_affiliation_strings":["Orthopaedic Surgery, \u2020Pathology, and \u2021Radiology, Free University Hospital, Amsterdam, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopaedic Surgery, \u2020Pathology, and \u2021Radiology, Free University Hospital, Amsterdam, The Netherlands","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5097585502","display_name":"Paul Y. Van Diest","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Paul Y. Van Diest","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111683373","display_name":"Radu A. Manoliu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I865915315","display_name":"Vrije Universiteit Amsterdam","ror":"https://ror.org/008xxew50","country_code":"NL","type":"education","lineage":["https://openalex.org/I865915315"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Radu A. Manoliu","raw_affiliation_strings":["Vrije Universiteit Amsterdam ,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Vrije Universiteit Amsterdam ,","institution_ids":["https://openalex.org/I865915315"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009193872","display_name":"Paul I.J.M. Wuisman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Paul I.J.M. Wuisman","raw_affiliation_strings":["Dr. Paul I. J. M. Wuisman; Department of Orthopaedic Surgery; Free University Hospital; Postbus 1117, 1007 MB Amsterdam; The Netherlands","Orthopaedic Surgery, \u2020Pathology, and \u2021Radiology, Free University Hospital, Amsterdam, The Netherlands","Department of Orthopaedic Surgery","Dr. Paul I. J. M. Wuisman","Free University Hospital","Postbus 1117, 1007 MB Amsterdam","The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dr. Paul I. J. M. Wuisman; Department of Orthopaedic Surgery; Free University Hospital; Postbus 1117, 1007 MB Amsterdam; The Netherlands","institution_ids":[]},{"raw_affiliation_string":"Orthopaedic Surgery, \u2020Pathology, and \u2021Radiology, Free University Hospital, Amsterdam, The Netherlands","institution_ids":[]},{"raw_affiliation_string":"Department of Orthopaedic Surgery","institution_ids":[]},{"raw_affiliation_string":"Dr. Paul I. J. M. Wuisman","institution_ids":[]},{"raw_affiliation_string":"Free University Hospital","institution_ids":[]},{"raw_affiliation_string":"Postbus 1117, 1007 MB Amsterdam","institution_ids":[]},{"raw_affiliation_string":"The Netherlands","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5009193872","https://openalex.org/A5049464780","https://openalex.org/A5080912741","https://openalex.org/A5109109001"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2125,"has_fulltext":false,"cited_by_count":7,"citation_normalized_percentile":{"value":0.5234849,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"23","issue":"17","first_page":"1895","last_page":"1899"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":0.8955000042915344,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":0.8955000042915344,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.03959999978542328,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12108","display_name":"Management of metastatic bone disease","score":0.014299999922513962,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-lymphocytic-leukemia","display_name":"chronic lymphocytic leukemia","score":0.996999979019165},{"id":"https://openalex.org/keywords/lumbar-disc","display_name":"lumbar intervertebral disc","score":0.4830000102519989},{"id":"https://openalex.org/keywords/b-cell-infiltration","display_name":"B cell infiltration","score":0.5019999742507935},{"id":"https://openalex.org/keywords/spinal-involvement","display_name":"spinal involvement","score":0.4090000092983246},{"id":"https://openalex.org/keywords/dural-compression","display_name":"dural compression","score":0.7260000109672546},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.7799999713897705},{"id":"https://openalex.org/keywords/en-bloc-resection","display_name":"en bloc resection","score":0.7210000157356262},{"id":"https://openalex.org/keywords/back-pain","display_name":"back pain","score":0.5799999833106995},{"id":"https://openalex.org/keywords/immunohistochemistry","display_name":"immunohistochemistry","score":0.7229999899864197}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9804902672767639},{"id":"https://openalex.org/C2777938653","wikidata":"https://www.wikidata.org/wiki/Q1088156","display_name":"Chronic lymphocytic leukemia","level":3,"score":0.6157069802284241},{"id":"https://openalex.org/C44575665","wikidata":"https://www.wikidata.org/wiki/Q1293405","display_name":"Lumbar","level":2,"score":0.5885549783706665},{"id":"https://openalex.org/C2777755357","wikidata":"https://www.wikidata.org/wiki/Q502781","display_name":"Intervertebral disc","level":2,"score":0.5334539413452148},{"id":"https://openalex.org/C2779835254","wikidata":"https://www.wikidata.org/wiki/Q405478","display_name":"Lumbar vertebrae","level":3,"score":0.42901864647865295},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.34631651639938354},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.32813912630081177},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.3047700524330139},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1626569926738739}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007403","descriptor_name":"Intervertebral Disc","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D007403","descriptor_name":"Intervertebral Disc","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D008159","descriptor_name":"Lumbar Vertebrae","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013123","descriptor_name":"Spinal Fusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015451","descriptor_name":"Leukemia, Lymphocytic, Chronic, B-Cell","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D015451","descriptor_name":"Leukemia, Lymphocytic, Chronic, B-Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D017254","descriptor_name":"Leukemic Infiltration","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D017254","descriptor_name":"Leukemic Infiltration","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1097/00007632-199809010-00020","doi":"https://doi.org/10.1097/00007632-199809010-00020","is_oa":false,"landing_page_url":"https://doi.org/10.1097/00007632-199809010-00020","pdf_url":null,"source":{"id":"https://openalex.org/S4026894","display_name":"Spine","issn_l":"0362-2436","issn":["0362-2436","1528-1159"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Spine","raw_type":"journal-article"},{"id":"pmid:9762748","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9762748","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Spine","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W47471900","https://openalex.org/W1966281576","https://openalex.org/W1992283730","https://openalex.org/W2012005830","https://openalex.org/W2047104971","https://openalex.org/W2049244720","https://openalex.org/W2056020138","https://openalex.org/W2132465564","https://openalex.org/W2139826054","https://openalex.org/W2223628199","https://openalex.org/W2320560338","https://openalex.org/W2323490326","https://openalex.org/W4239725976","https://openalex.org/W4249118391"],"related_works":["https://openalex.org/W2024653695","https://openalex.org/W1992283730","https://openalex.org/W2004781774","https://openalex.org/W2020399907","https://openalex.org/W2191563388","https://openalex.org/W2070905614","https://openalex.org/W2090758941","https://openalex.org/W2395851257","https://openalex.org/W2049244720","https://openalex.org/W1985100974"],"abstract_inverted_index":{"STUDY":[0],"DESIGN:":[1],"Report":[2],"of":[3,10,17,30,67,69,83,94,134,143,153,160,181,192,217,243],"a":[4,7,11,193],"patient":[5,203],"with":[6,139,148,166,172,178,230,249],"rare":[8,59],"location":[9],"solid":[12,91],"chronic":[13,31,61,74,104,218],"lymphocytic":[14,32,45,62,75,105,219],"leukemic":[15,95,179],"mass":[16,92],"an":[18,89],"intervertebral":[19,145],"lumbar":[20],"disc.":[21],"OBJECTIVES:":[22],"To":[23],"illustrate":[24],"the":[25,37,144,202,246],"previously":[26],"undescribed":[27],"discovertebral":[28],"involvement":[29,72,102,214],"leukemia":[33,46,63,76,106,220,244],"and":[34,53,64,79,119,126,137,141,163,169,189,195,208,233],"to":[35,88,258],"discuss":[36],"diagnostic":[38],"difficulties.":[39],"SUMMARY":[40],"OF":[41],"BACKGROUND":[42],"DATA:":[43],"Chronic":[44],"primarily":[47],"involves":[48],"lymph":[49],"nodes,":[50],"spleen,":[51],"liver,":[52],"bone":[54],"marrow.":[55],"Bone":[56],"lesions":[57],"are":[58,122],"in":[60,73,103,206,215,228,245],"usually":[65],"consist":[66],"areas":[68],"osteopenia.":[70],"Spinal":[71],"is":[77,221,256],"rare,":[78],"only":[80],"two":[81],"cases":[82,216],"spinal":[84],"cord":[85],"compression":[86],"attributable":[87],"extradural":[90],"composed":[93],"cells":[96,180],"have":[97],"been":[98,109,238],"reported.":[99],"Intervertebral":[100,175,212],"disc":[101,146,176,213],"has":[107],"not":[108],"reported":[110],"previously.":[111],"METHODS:":[112],"The":[113],"clinical":[114],"findings,":[115],"radiographs,":[116],"histology,":[117],"treatment,":[118],"follow-up":[120],"results":[121],"presented.":[123],"RESULTS:":[124],"Radiographs":[125],"magnetic":[127],"resonance":[128],"imaging":[129],"studies":[130,191],"showed":[131],"partial":[132],"collapse":[133],"vertebrae":[135,161],"L2":[136,162],"L3,":[138],"destruction":[140],"protrusion":[142],"L2-L3":[147],"dura":[149],"compression.":[150],"Treatment":[151],"consisted":[152],"radiotherapy":[154],"followed":[155],"by":[156],"en":[157],"bloc":[158],"resection":[159,196],"L3":[164],"stabilized":[165],"stackable":[167],"cages":[168],"anterior":[170],"fixation":[171],"Kaneda":[173],"bars.":[174],"infiltration":[177],"B-cell":[182],"origin":[183],"was":[184,204],"confirmed":[185],"through":[186],"histologic":[187],"examination":[188],"immunohistochemical":[190],"biopsy":[194],"specimen.":[197],"Twenty":[198],"months":[199],"after":[200],"treatment":[201],"still":[205],"remission":[207],"fully":[209],"mobilized.":[210],"CONCLUSIONS:":[211],"rare.":[222],"Its":[223],"presence":[224],"should":[225],"be":[226,253],"considered":[227],"patients":[229],"back":[231],"pain":[232],"neurologic":[234],"symptoms":[235],"who":[236],"had":[237],"treated":[239],"for":[240],"this":[241],"form":[242],"past.":[247],"Differentiation":[248],"infectious":[250],"spondylodiscitis":[251],"can":[252],"difficult.":[254],"Histology":[255],"necessary":[257],"confirm":[259],"diagnosis.":[260]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}