{"id":"https://openalex.org/W2035351900","doi":"https://doi.org/10.1007/s10495-010-0532-6","title":"Multiwalled carbon nanotubes activate NF-\u03baB and AP-1 signaling pathways to induce apoptosis in rat lung epithelial cells","display_name":"Multiwalled carbon nanotubes activate NF-\u03baB and AP-1 signaling pathways to induce apoptosis in rat lung epithelial cells","publication_year":2010,"publication_date":"2010-08-07","ids":{"openalex":"https://openalex.org/W2035351900","doi":"https://doi.org/10.1007/s10495-010-0532-6","mag":"2035351900","pmid":"https://pubmed.ncbi.nlm.nih.gov/20694747"},"language":"en","primary_location":{"id":"doi:10.1007/s10495-010-0532-6","doi":"https://doi.org/10.1007/s10495-010-0532-6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10495-010-0532-6","pdf_url":null,"source":{"id":"https://openalex.org/S120502300","display_name":"APOPTOSIS","issn_l":"1360-8185","issn":["1360-8185","1573-675X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Apoptosis","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5036621071","display_name":"Prabakaran Ravichandran","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I103087548","display_name":"Norfolk State University","ror":"https://ror.org/030pydv62","country_code":"US","type":"education","lineage":["https://openalex.org/I103087548"]},{"id":"https://openalex.org/I48205209","display_name":"Texas Southern University","ror":"https://ror.org/05ch0aw77","country_code":"US","type":"education","lineage":["https://openalex.org/I48205209"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Prabakaran Ravichandran","raw_affiliation_strings":["Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA 23504, USA","Norfolk State University","Texas Southern University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA 23504, USA","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Norfolk State University","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Texas Southern University","institution_ids":["https://openalex.org/I48205209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002322591","display_name":"Sudhakar Baluchamy","orcid":"https://orcid.org/0000-0003-2398-8480","observed_orcids":["https://orcid.org/0000-0003-2398-8480"]},"institutions":[{"id":"https://openalex.org/I103087548","display_name":"Norfolk State University","ror":"https://ror.org/030pydv62","country_code":"US","type":"education","lineage":["https://openalex.org/I103087548"]},{"id":"https://openalex.org/I48205209","display_name":"Texas Southern University","ror":"https://ror.org/05ch0aw77","country_code":"US","type":"education","lineage":["https://openalex.org/I48205209"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sudhakar Baluchamy","raw_affiliation_strings":["Department of Biology, Texas Southern University, Houston, TX, 77004, USA","Department of Biology, Texas Southern University, Houston, USA","Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, USA","Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA, 23504, USA","Norfolk State University","Texas Southern University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Texas Southern University, Houston, TX, 77004, USA","institution_ids":["https://openalex.org/I48205209"]},{"raw_affiliation_string":"Department of Biology, Texas Southern University, Houston, USA","institution_ids":["https://openalex.org/I48205209"]},{"raw_affiliation_string":"Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, USA","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA, 23504, USA","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Norfolk State University","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Texas Southern University","institution_ids":["https://openalex.org/I48205209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003523272","display_name":"Bindhu Sadanandan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I103087548","display_name":"Norfolk State University","ror":"https://ror.org/030pydv62","country_code":"US","type":"education","lineage":["https://openalex.org/I103087548"]},{"id":"https://openalex.org/I48205209","display_name":"Texas Southern University","ror":"https://ror.org/05ch0aw77","country_code":"US","type":"education","lineage":["https://openalex.org/I48205209"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bindhu Sadanandan","raw_affiliation_strings":["Department of Biology, Texas Southern University, Houston, TX, 77004, USA","Department of Biology, Texas Southern University, Houston, USA","Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, USA","Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA, 23504, USA","Norfolk State University","Texas Southern University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Texas Southern University, Houston, TX, 77004, USA","institution_ids":["https://openalex.org/I48205209"]},{"raw_affiliation_string":"Department of Biology, Texas Southern University, Houston, USA","institution_ids":["https://openalex.org/I48205209"]},{"raw_affiliation_string":"Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, USA","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA, 23504, USA","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Norfolk State University","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Texas Southern University","institution_ids":["https://openalex.org/I48205209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5090768798","display_name":"Ramya Gopikrishnan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I103087548","display_name":"Norfolk State University","ror":"https://ror.org/030pydv62","country_code":"US","type":"education","lineage":["https://openalex.org/I103087548"]},{"id":"https://openalex.org/I48205209","display_name":"Texas Southern University","ror":"https://ror.org/05ch0aw77","country_code":"US","type":"education","lineage":["https://openalex.org/I48205209"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ramya Gopikrishnan","raw_affiliation_strings":["Department of Biology, Texas Southern University, Houston, TX, 77004, USA","Department of Biology, Texas Southern University, Houston, USA","Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, USA","Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA, 23504, USA","Norfolk State University","Texas Southern University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Texas Southern University, Houston, TX, 77004, USA","institution_ids":["https://openalex.org/I48205209"]},{"raw_affiliation_string":"Department of Biology, Texas Southern University, Houston, USA","institution_ids":["https://openalex.org/I48205209"]},{"raw_affiliation_string":"Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, USA","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA, 23504, USA","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Norfolk State University","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Texas Southern University","institution_ids":["https://openalex.org/I48205209"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Santosh Biradar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I103087548","display_name":"Norfolk State University","ror":"https://ror.org/030pydv62","country_code":"US","type":"education","lineage":["https://openalex.org/I103087548"]},{"id":"https://openalex.org/I48205209","display_name":"Texas Southern University","ror":"https://ror.org/05ch0aw77","country_code":"US","type":"education","lineage":["https://openalex.org/I48205209"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Santosh Biradar","raw_affiliation_strings":["Department of Biology, Texas Southern University, Houston, TX, 77004, USA","Department of Biology, Texas Southern University, Houston, USA","Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, USA","Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA, 23504, USA","Norfolk State University","Texas Southern University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Texas Southern University, Houston, TX, 77004, USA","institution_ids":["https://openalex.org/I48205209"]},{"raw_affiliation_string":"Department of Biology, Texas Southern University, Houston, USA","institution_ids":["https://openalex.org/I48205209"]},{"raw_affiliation_string":"Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, USA","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA, 23504, USA","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Norfolk State University","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Texas Southern University","institution_ids":["https://openalex.org/I48205209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061247875","display_name":"Vani Ramesh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I103087548","display_name":"Norfolk State University","ror":"https://ror.org/030pydv62","country_code":"US","type":"education","lineage":["https://openalex.org/I103087548"]},{"id":"https://openalex.org/I48205209","display_name":"Texas Southern University","ror":"https://ror.org/05ch0aw77","country_code":"US","type":"education","lineage":["https://openalex.org/I48205209"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vani Ramesh","raw_affiliation_strings":["Department of Biology, Texas Southern University, Houston, TX, 77004, USA","Department of Biology, Texas Southern University, Houston, USA","Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, USA","Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA, 23504, USA","Norfolk State University","Texas Southern University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Texas Southern University, Houston, TX, 77004, USA","institution_ids":["https://openalex.org/I48205209"]},{"raw_affiliation_string":"Department of Biology, Texas Southern University, Houston, USA","institution_ids":["https://openalex.org/I48205209"]},{"raw_affiliation_string":"Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, USA","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA, 23504, USA","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Norfolk State University","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Texas Southern University","institution_ids":["https://openalex.org/I48205209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110118967","display_name":"Joseph C. Hall","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I103087548","display_name":"Norfolk State University","ror":"https://ror.org/030pydv62","country_code":"US","type":"education","lineage":["https://openalex.org/I103087548"]},{"id":"https://openalex.org/I48205209","display_name":"Texas Southern University","ror":"https://ror.org/05ch0aw77","country_code":"US","type":"education","lineage":["https://openalex.org/I48205209"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph C. Hall","raw_affiliation_strings":["Department of Biology, Texas Southern University, Houston, TX, 77004, USA","Department of Biology, Texas Southern University, Houston, USA","Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, USA","Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA, 23504, USA","Norfolk State University","Texas Southern University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Texas Southern University, Houston, TX, 77004, USA","institution_ids":["https://openalex.org/I48205209"]},{"raw_affiliation_string":"Department of Biology, Texas Southern University, Houston, USA","institution_ids":["https://openalex.org/I48205209"]},{"raw_affiliation_string":"Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, USA","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA, 23504, USA","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Norfolk State University","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Texas Southern University","institution_ids":["https://openalex.org/I48205209"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003764354","display_name":"Govindarajan T. Ramesh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I103087548","display_name":"Norfolk State University","ror":"https://ror.org/030pydv62","country_code":"US","type":"education","lineage":["https://openalex.org/I103087548"]},{"id":"https://openalex.org/I48205209","display_name":"Texas Southern University","ror":"https://ror.org/05ch0aw77","country_code":"US","type":"education","lineage":["https://openalex.org/I48205209"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Govindarajan T. Ramesh","raw_affiliation_strings":["Department of Biology, Texas Southern University, Houston, TX, 77004, USA","Department of Biology, Texas Southern University, Houston, USA","Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, USA","Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA, 23504, USA","Norfolk State University","Texas Southern University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Texas Southern University, Houston, TX, 77004, USA","institution_ids":["https://openalex.org/I48205209"]},{"raw_affiliation_string":"Department of Biology, Texas Southern University, Houston, USA","institution_ids":["https://openalex.org/I48205209"]},{"raw_affiliation_string":"Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, USA","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Molecular Toxicology Laboratory, Center for Biotechnology and Biomedical Sciences, Department of Biology, Norfolk State University, Norfolk, VA, 23504, USA","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Norfolk State University","institution_ids":["https://openalex.org/I103087548"]},{"raw_affiliation_string":"Texas Southern University","institution_ids":["https://openalex.org/I48205209"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5003764354"],"corresponding_institution_ids":["https://openalex.org/I103087548","https://openalex.org/I48205209"],"apc_list":{"value":5090,"currency":"USD","value_usd":5090},"apc_paid":null,"fwci":2.7336,"has_fulltext":false,"cited_by_count":78,"citation_normalized_percentile":{"value":0.90505418,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"15","issue":"12","first_page":"1507","last_page":"1516"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.8192999958992004,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.8192999958992004,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12627","display_name":"Graphene and Nanomaterials Applications","score":0.1348000019788742,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11591","display_name":"NF-\u03baB Signaling Pathways","score":0.016300000250339508,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multi-walled-carbon-nanotubes","display_name":"multi-walled carbon nanotubes","score":0.9700000286102295},{"id":"https://openalex.org/keywords/nanoparticle-toxicity","display_name":"nanoparticle toxicity","score":0.7730000019073486},{"id":"https://openalex.org/keywords/nf-kappab-signaling","display_name":"NF-\u03baB signaling","score":0.953000009059906},{"id":"https://openalex.org/keywords/ap-1-signaling","display_name":"AP-1 signaling","score":0.9290000200271606},{"id":"https://openalex.org/keywords/lung-epithelial-cells","display_name":"lung epithelial cells","score":0.9800000190734863},{"id":"https://openalex.org/keywords/dna-damage","display_name":"DNA damage","score":0.9010000228881836},{"id":"https://openalex.org/keywords/mitochondrial-membrane-integrity","display_name":"mitochondrial membrane integrity","score":0.7260000109672546},{"id":"https://openalex.org/keywords/cytochrome-c-release","display_name":"cytochrome c release","score":0.9959999918937683},{"id":"https://openalex.org/keywords/ikappabalpha-degradation","display_name":"I\u03baB\u03b1 degradation","score":0.875},{"id":"https://openalex.org/keywords/p53","display_name":"p53","score":0.8159999847412109},{"id":"https://openalex.org/keywords/bax","display_name":"Bax","score":0.8360000252723694},{"id":"https://openalex.org/keywords/p21","display_name":"p21","score":0.9399999976158142},{"id":"https://openalex.org/keywords/apoptosis-inducing-factor","display_name":"apoptosis-inducing factor","score":0.875},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.546999990940094}],"concepts":[{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.7637218236923218},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7484758496284485},{"id":"https://openalex.org/C98539663","wikidata":"https://www.wikidata.org/wiki/Q220599","display_name":"Cytosol","level":3,"score":0.6394339799880981},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.6340026259422302},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.6134830713272095},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.6103509664535522},{"id":"https://openalex.org/C29311851","wikidata":"https://www.wikidata.org/wiki/Q408223","display_name":"Cytochrome c","level":3,"score":0.5642982721328735},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.5480596423149109},{"id":"https://openalex.org/C28859421","wikidata":"https://www.wikidata.org/wiki/Q39572","display_name":"Mitochondrion","level":2,"score":0.4905492663383484},{"id":"https://openalex.org/C98424977","wikidata":"https://www.wikidata.org/wiki/Q25805","display_name":"Caspase","level":4,"score":0.48288917541503906},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4522344768047333},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3725680708885193},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20270338654518127},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.14589673280715942},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.05484685301780701}],"mesh":[{"descriptor_ui":"D000255","descriptor_name":"Adenosine Triphosphate","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003576","descriptor_name":"Electron Transport Complex IV","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D004789","descriptor_name":"Enzyme Activation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D004789","descriptor_name":"Enzyme Activation","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008168","descriptor_name":"Lung","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008928","descriptor_name":"Mitochondria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016328","descriptor_name":"NF-kappa B","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018808","descriptor_name":"Transcription Factor AP-1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020545","descriptor_name":"Respiratory Mucosa","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D020545","descriptor_name":"Respiratory Mucosa","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D020545","descriptor_name":"Respiratory Mucosa","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D025521","descriptor_name":"Tumor Suppressor Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D036103","descriptor_name":"Nanotechnology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D037742","descriptor_name":"Nanotubes, Carbon","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D045304","descriptor_name":"Cytochromes c","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D051033","descriptor_name":"Apoptosis Inducing Factor","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053078","descriptor_name":"Membrane Potential, Mitochondrial","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D053078","descriptor_name":"Membrane Potential, Mitochondrial","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s10495-010-0532-6","doi":"https://doi.org/10.1007/s10495-010-0532-6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10495-010-0532-6","pdf_url":null,"source":{"id":"https://openalex.org/S120502300","display_name":"APOPTOSIS","issn_l":"1360-8185","issn":["1360-8185","1573-675X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Apoptosis","raw_type":"journal-article"},{"id":"pmid:20694747","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20694747","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Apoptosis : an international journal on programmed cell death","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1308767498","display_name":"RIMI: Center for Biotechnology & Biomedical Sciences","funder_award_id":"P20MD001822","funder_id":"https://openalex.org/F4320337534","funder_display_name":"National Institute on Minority Health and Health Disparities"}],"funders":[{"id":"https://openalex.org/F4320306101","display_name":"National Aeronautics and Space Administration","ror":"https://ror.org/027ka1x80"},{"id":"https://openalex.org/F4320337534","display_name":"National Institute on Minority Health and Health Disparities","ror":"https://ror.org/0493hgw16"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W1526999767","https://openalex.org/W1607777232","https://openalex.org/W1661180389","https://openalex.org/W1853499144","https://openalex.org/W1904882776","https://openalex.org/W1964237645","https://openalex.org/W1965902122","https://openalex.org/W1975924701","https://openalex.org/W1979018407","https://openalex.org/W1979839814","https://openalex.org/W1986166754","https://openalex.org/W1987641638","https://openalex.org/W1989202967","https://openalex.org/W1993816077","https://openalex.org/W2006791781","https://openalex.org/W2010424690","https://openalex.org/W2011299920","https://openalex.org/W2011568772","https://openalex.org/W2011934320","https://openalex.org/W2027097222","https://openalex.org/W2028703999","https://openalex.org/W2046421373","https://openalex.org/W2052971899","https://openalex.org/W2055751648","https://openalex.org/W2058714321","https://openalex.org/W2059901024","https://openalex.org/W2061726942","https://openalex.org/W2063669247","https://openalex.org/W2064476069","https://openalex.org/W2069544210","https://openalex.org/W2070538522","https://openalex.org/W2075003503","https://openalex.org/W2079481175","https://openalex.org/W2094893112","https://openalex.org/W2094963548","https://openalex.org/W2095344091","https://openalex.org/W2099781344","https://openalex.org/W2106791134","https://openalex.org/W2106969589","https://openalex.org/W2111163976","https://openalex.org/W2126705024","https://openalex.org/W2128230974","https://openalex.org/W2129169350","https://openalex.org/W2151609134","https://openalex.org/W2163704839","https://openalex.org/W2170657861","https://openalex.org/W4245283036"],"related_works":["https://openalex.org/W2967899326","https://openalex.org/W2129169350","https://openalex.org/W2004898838","https://openalex.org/W1996232326","https://openalex.org/W2058199605","https://openalex.org/W2039696488","https://openalex.org/W2461526504","https://openalex.org/W4389725375","https://openalex.org/W3028665818","https://openalex.org/W2071776935"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":9},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}