{"id":"https://openalex.org/W2035118693","doi":"https://doi.org/10.1016/0198-8859(86)90021-2","title":"Genetics of the antibody response to an endothelial transplantation antigen in the rat","display_name":"Genetics of the antibody response to an endothelial transplantation antigen in the rat","publication_year":1986,"publication_date":"1986-02-01","ids":{"openalex":"https://openalex.org/W2035118693","doi":"https://doi.org/10.1016/0198-8859(86)90021-2","mag":"2035118693","pmid":"https://pubmed.ncbi.nlm.nih.gov/3949552"},"language":"en","primary_location":{"id":"doi:10.1016/0198-8859(86)90021-2","doi":"https://doi.org/10.1016/0198-8859(86)90021-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0198-8859(86)90021-2","pdf_url":null,"source":{"id":"https://openalex.org/S6860681","display_name":"Human Immunology","issn_l":"0198-8859","issn":["0198-8859","1879-1166"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033685794","display_name":"Jan J. Blankert","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL","US"],"is_corresponding":true,"raw_author_name":"Jan J. Blankert","raw_affiliation_strings":["Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania USA","Renal Division, Department of Medicine, University Hospital Leiden, 2333 AA Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Renal Division, Department of Medicine, University Hospital Leiden, 2333 AA Leiden, The Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110017691","display_name":"Leendert A. van Es","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL","US"],"is_corresponding":false,"raw_author_name":"Leendert A. van Es","raw_affiliation_strings":["Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania USA","Renal Division, Department of Medicine, University Hospital Leiden, 2333 AA Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Renal Division, Department of Medicine, University Hospital Leiden, 2333 AA Leiden, The Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111717103","display_name":"Heinz W. Kunz","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL","US"],"is_corresponding":false,"raw_author_name":"Heinz W. Kunz","raw_affiliation_strings":["Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania USA","Renal Division, Department of Medicine, University Hospital Leiden, 2333 AA Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Renal Division, Department of Medicine, University Hospital Leiden, 2333 AA Leiden, The Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109918591","display_name":"Donald V. Cramer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL","US"],"is_corresponding":false,"raw_author_name":"Donald V. Cramer","raw_affiliation_strings":["Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania USA","Renal Division, Department of Medicine, University Hospital Leiden, 2333 AA Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Renal Division, Department of Medicine, University Hospital Leiden, 2333 AA Leiden, The Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5107659002","display_name":"Leendert C. Paul","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I2800006345","display_name":"Leiden University Medical Center","ror":"https://ror.org/05xvt9f17","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2800006345"]}],"countries":["NL","US"],"is_corresponding":false,"raw_author_name":"Leendert C. Paul","raw_affiliation_strings":["Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania USA","Renal Division, Department of Medicine, University Hospital Leiden, 2333 AA Leiden, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Pittsburgh, School of Medicine, Pittsburgh, Pennsylvania USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Renal Division, Department of Medicine, University Hospital Leiden, 2333 AA Leiden, The Netherlands","institution_ids":["https://openalex.org/I2800006345"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5033685794"],"corresponding_institution_ids":["https://openalex.org/I170201317","https://openalex.org/I2800006345"],"apc_list":{"value":3600,"currency":"USD","value_usd":3600},"apc_paid":null,"fwci":1.9895,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.84677419,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"15","issue":"2","first_page":"125","last_page":"136"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.8349999785423279,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10373","display_name":"Renal Transplantation Outcomes and Treatments","score":0.8349999785423279,"subfield":{"id":"https://openalex.org/subfields/2747","display_name":"Transplantation"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.08529999852180481,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11189","display_name":"Transplantation: Methods and Outcomes","score":0.01720000058412552,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/alloantibody-response","display_name":"alloantibody response","score":0.8399999737739563},{"id":"https://openalex.org/keywords/mhc-class-ii","display_name":"MHC class II","score":0.7020000219345093},{"id":"https://openalex.org/keywords/thymus-dependent-immunity","display_name":"thymus-dependent immunity","score":0.7020000219345093},{"id":"https://openalex.org/keywords/athymic-nude-rats","display_name":"athymic nude rats","score":0.781000018119812},{"id":"https://openalex.org/keywords/mhc-matching","display_name":"MHC compatibility","score":0.5289999842643738}],"concepts":[{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.6920043230056763},{"id":"https://openalex.org/C147483822","wikidata":"https://www.wikidata.org/wiki/Q103537","display_name":"Antigen","level":2,"score":0.6537333726882935},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5766681432723999},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.5702025294303894},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5668153166770935},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.5393517017364502},{"id":"https://openalex.org/C207936829","wikidata":"https://www.wikidata.org/wiki/Q423163","display_name":"Major histocompatibility complex","level":3,"score":0.5076471567153931},{"id":"https://openalex.org/C2780931953","wikidata":"https://www.wikidata.org/wiki/Q9371","display_name":"Spleen","level":2,"score":0.44061052799224854},{"id":"https://openalex.org/C202965653","wikidata":"https://www.wikidata.org/wiki/Q2664028","display_name":"Histocompatibility","level":4,"score":0.43661853671073914},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.22143638134002686},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.12763115763664246},{"id":"https://openalex.org/C188280979","wikidata":"https://www.wikidata.org/wiki/Q911125","display_name":"Human leukocyte antigen","level":3,"score":0.11497768759727478}],"mesh":[{"descriptor_ui":"D000483","descriptor_name":"Alleles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000917","descriptor_name":"Antibody Formation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003433","descriptor_name":"Crosses, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004727","descriptor_name":"Endothelium","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006649","descriptor_name":"Histocompatibility Antigens","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007518","descriptor_name":"Isoantibodies","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D007668","descriptor_name":"Kidney","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008040","descriptor_name":"Genetic Linkage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008198","descriptor_name":"Lymph Nodes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008285","descriptor_name":"Major Histocompatibility Complex","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011919","descriptor_name":"Rats, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013154","descriptor_name":"Spleen","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0198-8859(86)90021-2","doi":"https://doi.org/10.1016/0198-8859(86)90021-2","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0198-8859(86)90021-2","pdf_url":null,"source":{"id":"https://openalex.org/S6860681","display_name":"Human Immunology","issn_l":"0198-8859","issn":["0198-8859","1879-1166"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Immunology","raw_type":"journal-article"},{"id":"pmid:3949552","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3949552","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human immunology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8560000061988831}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2485742512","display_name":null,"funder_award_id":"HD 08662","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G4126571968","display_name":"ALLOZYME VARIATION IN NATURAL POPULATIONS","funder_award_id":"R01GM032580","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W27026813","https://openalex.org/W1418054816","https://openalex.org/W1502613791","https://openalex.org/W1534917558","https://openalex.org/W1560806276","https://openalex.org/W1561969582","https://openalex.org/W1965469345","https://openalex.org/W1973747451","https://openalex.org/W1974099548","https://openalex.org/W1974240054","https://openalex.org/W1977421895","https://openalex.org/W2011561945","https://openalex.org/W2025816637","https://openalex.org/W2033935240","https://openalex.org/W2048087293","https://openalex.org/W2048157928","https://openalex.org/W2051357120","https://openalex.org/W2060183661","https://openalex.org/W2071864665","https://openalex.org/W2082466768","https://openalex.org/W2085619452","https://openalex.org/W2091402324","https://openalex.org/W2092262156","https://openalex.org/W2136991899","https://openalex.org/W2137987015","https://openalex.org/W2395898778","https://openalex.org/W2396138688","https://openalex.org/W2398526430","https://openalex.org/W4250457363","https://openalex.org/W4313376949","https://openalex.org/W6712474298"],"related_works":["https://openalex.org/W1974240054","https://openalex.org/W2017344315","https://openalex.org/W2417941481","https://openalex.org/W2048087293","https://openalex.org/W2092262156","https://openalex.org/W1994007688","https://openalex.org/W4240857070","https://openalex.org/W1977421895","https://openalex.org/W2103253357","https://openalex.org/W2009361524"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}
