{"id":"https://openalex.org/W2034966705","doi":"https://doi.org/10.1111/j.1530-0277.1995.tb00992.x","title":"Brain Proton Magnetic Resonance Spectroscopy Studies in Recently Abstinent Alcoholics*","display_name":"Brain Proton Magnetic Resonance Spectroscopy Studies in Recently Abstinent Alcoholics*","publication_year":1995,"publication_date":"1995-08-01","ids":{"openalex":"https://openalex.org/W2034966705","doi":"https://doi.org/10.1111/j.1530-0277.1995.tb00992.x","mag":"2034966705","pmid":"https://pubmed.ncbi.nlm.nih.gov/7485820"},"language":"en","primary_location":{"id":"doi:10.1111/j.1530-0277.1995.tb00992.x","doi":"https://doi.org/10.1111/j.1530-0277.1995.tb00992.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1530-0277.1995.tb00992.x","pdf_url":null,"source":{"id":"https://openalex.org/S115510430","display_name":"Alcoholism Clinical and Experimental Research","issn_l":"0145-6008","issn":["0145-6008","1530-0277","2993-7175"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alcoholism: Clinical and Experimental Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5073077661","display_name":"Peter Martin","orcid":"https://orcid.org/0000-0002-9781-4961","observed_orcids":["https://orcid.org/0000-0002-9781-4961"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Peter R. Martin","raw_affiliation_strings":["Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA","Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee","Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]},{"raw_affiliation_string":"Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014129907","display_name":"S. Julian Gibbs","orcid":"https://orcid.org/0000-0002-2176-8970","observed_orcids":["https://orcid.org/0000-0002-2176-8970"]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S. Julian Gibbs","raw_affiliation_strings":["Department of Radiology and Radiological Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Radiological Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075049199","display_name":"A. Nimmerrichter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amanda A. Nimmerrichter","raw_affiliation_strings":["Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110537869","display_name":"William R. Riddle","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William R. Riddle","raw_affiliation_strings":["Department of Radiology and Radiological Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Radiological Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086043164","display_name":"Larry W. Welch","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Larry W. Welch","raw_affiliation_strings":["Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, Tennessee","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046882675","display_name":"M. Robert Willcott","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I901861585","display_name":"Vanderbilt University Medical Center","ror":"https://ror.org/05dq2gs74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210162197","https://openalex.org/I901861585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M. Robert Willcott","raw_affiliation_strings":["Department of Radiology and Radiological Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology and Radiological Sciences, Vanderbilt University School of Medicine, Nashville, Tennessee","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5073077661"],"corresponding_institution_ids":["https://openalex.org/I200719446","https://openalex.org/I901861585"],"apc_list":{"value":4110,"currency":"USD","value_usd":4110},"apc_paid":null,"fwci":1.4852,"has_fulltext":false,"cited_by_count":89,"citation_normalized_percentile":{"value":0.81947312,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"19","issue":"4","first_page":"1078","last_page":"1082"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12494","display_name":"Alcoholism and Thiamine Deficiency","score":0.49000000953674316,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12494","display_name":"Alcoholism and Thiamine Deficiency","score":0.49000000953674316,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10378","display_name":"Advanced MRI Techniques and Applications","score":0.3118000030517578,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10043","display_name":"Substance Abuse Treatment and Outcomes","score":0.14219999313354492,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chronic-alcoholism","display_name":"chronic alcoholism","score":0.8119999766349792},{"id":"https://openalex.org/keywords/alcohol-abstinence","display_name":"alcohol abstinence","score":0.9359999895095825},{"id":"https://openalex.org/keywords/cerebral-metabolism","display_name":"brain metabolism","score":0.4320000112056732},{"id":"https://openalex.org/keywords/choline","display_name":"choline","score":0.6980000138282776},{"id":"https://openalex.org/keywords/n-acetylaspartate","display_name":"N-acetylaspartate","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cho-naa-ratio","display_name":"Cho/NAA ratio","score":0.9399999976158142},{"id":"https://openalex.org/keywords/alcohol-related-dementia","display_name":"alcohol-related dementia","score":0.8029999732971191},{"id":"https://openalex.org/keywords/relapse","display_name":"relapse","score":0.8019999861717224},{"id":"https://openalex.org/keywords/alcohol-withdrawal-management","display_name":"alcohol detoxification","score":0.7799999713897705},{"id":"https://openalex.org/keywords/brain-atrophy","display_name":"brain atrophy","score":0.5569999814033508},{"id":"https://openalex.org/keywords/neurobehavioral-deficits","display_name":"neurobehavioral deficits","score":0.8050000071525574}],"concepts":[{"id":"https://openalex.org/C2780687700","wikidata":"https://www.wikidata.org/wiki/Q210978","display_name":"Abstinence","level":2,"score":0.8505221009254456},{"id":"https://openalex.org/C2781123555","wikidata":"https://www.wikidata.org/wiki/Q193166","display_name":"Choline","level":2,"score":0.6348794102668762},{"id":"https://openalex.org/C2988005100","wikidata":"https://www.wikidata.org/wiki/Q1979695","display_name":"Proton magnetic resonance","level":2,"score":0.6305298209190369},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.5737173557281494},{"id":"https://openalex.org/C2780168142","wikidata":"https://www.wikidata.org/wiki/Q3078809","display_name":"Cerebellar vermis","level":3,"score":0.5561690926551819},{"id":"https://openalex.org/C2779652256","wikidata":"https://www.wikidata.org/wiki/Q130983","display_name":"Cerebellum","level":2,"score":0.5090979933738708},{"id":"https://openalex.org/C2779436514","wikidata":"https://www.wikidata.org/wiki/Q4713263","display_name":"Alcohol dependence","level":3,"score":0.47533372044563293},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.44385841488838196},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.44118624925613403},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4395953416824341},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3991459012031555},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3644704520702362},{"id":"https://openalex.org/C2781066024","wikidata":"https://www.wikidata.org/wiki/Q156","display_name":"Alcohol","level":2,"score":0.3446299731731415},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3284730613231659},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.32749584317207336},{"id":"https://openalex.org/C46141821","wikidata":"https://www.wikidata.org/wiki/Q209402","display_name":"Nuclear magnetic resonance","level":1,"score":0.30152255296707153},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.27157944440841675},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.14942312240600586},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13197457790374756},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.06879487633705139},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000437","descriptor_name":"Alcoholism","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D000437","descriptor_name":"Alcoholism","qualifier_ui":"Q000534","qualifier_name":"rehabilitation","is_major_topic":true},{"descriptor_ui":"D001224","descriptor_name":"Aspartic Acid","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":false},{"descriptor_ui":"D001224","descriptor_name":"Aspartic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001284","descriptor_name":"Atrophy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D002531","descriptor_name":"Cerebellum","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002794","descriptor_name":"Choline","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009483","descriptor_name":"Neuropsychological Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012016","descriptor_name":"Reference Values","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1530-0277.1995.tb00992.x","doi":"https://doi.org/10.1111/j.1530-0277.1995.tb00992.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1530-0277.1995.tb00992.x","pdf_url":null,"source":{"id":"https://openalex.org/S115510430","display_name":"Alcoholism Clinical and Experimental Research","issn_l":"0145-6008","issn":["0145-6008","1530-0277","2993-7175"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alcoholism: Clinical and Experimental Research","raw_type":"journal-article"},{"id":"pmid:7485820","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7485820","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Alcoholism, clinical and experimental research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[{"id":"https://openalex.org/G8182514292","display_name":"GENETIC MECHANISMS OF ALCOHOLIC ORGANIC BRAIN DISEASE","funder_award_id":"R01AA008492","funder_id":"https://openalex.org/F4320337330","funder_display_name":"National Institute on Alcohol Abuse and Alcoholism"}],"funders":[{"id":"https://openalex.org/F4320337330","display_name":"National Institute on Alcohol Abuse and Alcoholism","ror":"https://ror.org/02jzrsm59"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W1567805674","https://openalex.org/W1578292768","https://openalex.org/W1595992644","https://openalex.org/W1745420251","https://openalex.org/W1847168837","https://openalex.org/W1950302860","https://openalex.org/W1968331384","https://openalex.org/W1971503795","https://openalex.org/W1978515376","https://openalex.org/W1987081043","https://openalex.org/W1990495050","https://openalex.org/W1991350649","https://openalex.org/W1992324032","https://openalex.org/W1996472177","https://openalex.org/W2007156170","https://openalex.org/W2007451611","https://openalex.org/W2012656038","https://openalex.org/W2016853306","https://openalex.org/W2019473524","https://openalex.org/W2019556431","https://openalex.org/W2020680876","https://openalex.org/W2033800655","https://openalex.org/W2037049184","https://openalex.org/W2037252045","https://openalex.org/W2040209778","https://openalex.org/W2054475402","https://openalex.org/W2054986991","https://openalex.org/W2058027749","https://openalex.org/W2058432924","https://openalex.org/W2060641585","https://openalex.org/W2066797205","https://openalex.org/W2077736310","https://openalex.org/W2081947248","https://openalex.org/W2085283110","https://openalex.org/W2086495001","https://openalex.org/W2088342663","https://openalex.org/W2089692573","https://openalex.org/W2090416329","https://openalex.org/W2093613378","https://openalex.org/W2093850626","https://openalex.org/W2104051447","https://openalex.org/W2104324875","https://openalex.org/W2113224712","https://openalex.org/W2132915698","https://openalex.org/W2142817371","https://openalex.org/W2152546327","https://openalex.org/W2210113849","https://openalex.org/W2470738768","https://openalex.org/W2473955680","https://openalex.org/W2885123497","https://openalex.org/W4230380100"],"related_works":["https://openalex.org/W2062239429","https://openalex.org/W2074287439","https://openalex.org/W2245246015","https://openalex.org/W7099232479","https://openalex.org/W2029873696","https://openalex.org/W2008943000","https://openalex.org/W3032690031","https://openalex.org/W2405767164","https://openalex.org/W1974682461","https://openalex.org/W2019060331"],"abstract_inverted_index":{"Chronic":[0],"alcohol-dependent":[1],"patients":[2,71],"have":[3],"reduced":[4,118],"brain":[5,100,135],"volumes":[6],"and":[7,66],"concomitant":[8],"neurobehavioral":[9],"deficits":[10],"that":[11],"may":[12],"recover":[13],"during":[14,31],"abstinence.":[15],"In":[16],"10":[17],"chronic":[18],"alcoholic":[19,112],"patients,":[20],"using":[21],"localized":[22],"proton":[23],"magnetic":[24],"resonance":[25],"spectroscopy,":[26],"we":[27],"found":[28],"reliable":[29],"increases":[30],"the":[32,39,42,52,70,81,90,127],"first":[33],"3-4":[34],"weeks":[35],"of":[36,46,64,69,99,121,126],"abstinence":[37],"in":[38,67,80,107,114,124],"concentrations":[40,120],"within":[41],"superior":[43],"cerebellar":[44],"vermis":[45],"choline":[47],"(Cho)-containing":[48],"compounds":[49],"relative":[50,119],"to":[51,117],"neuronal":[53],"marker,":[54],"N-acetylaspartate":[55],"(NAA).":[56],"Lesser":[57],"changes":[58,137],"were":[59],"observed":[60,106],"following":[61],"1":[62],"month":[63],"abstinence,":[65],"one":[68],"studied":[72],"longitudinally":[73],"over":[74],"3":[75],"months,":[76],"a":[77,95,108],"marked":[78],"reduction":[79],"Cho/NAA":[82,91,104],"ratio":[83,92],"was":[84,105],"associated":[85],"with":[86,94,110],"relapse.":[87],"After":[88],"detoxification,":[89],"correlated":[93],"composite":[96],"clinical":[97],"impression":[98],"functions.":[101],"The":[102],"lowest":[103],"patient":[109],"persisting":[111],"dementia,":[113],"striking":[115],"contrast":[116],"NAA":[122],"reported":[123],"dementia":[125],"Alzheimer's":[128],"type.":[129],"Possible":[130],"molecular":[131],"explanations":[132],"for":[133],"these":[134],"metabolic":[136],"are":[138],"discussed.":[139]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}