{"id":"https://openalex.org/W2034631663","doi":"https://doi.org/10.3109/02652049009028420","title":"In vitrodiffusion in polyacrylamide embedded agarose microbeads","display_name":"In vitrodiffusion in polyacrylamide embedded agarose microbeads","publication_year":1990,"publication_date":"1990-01-01","ids":{"openalex":"https://openalex.org/W2034631663","doi":"https://doi.org/10.3109/02652049009028420","mag":"2034631663","pmid":"https://pubmed.ncbi.nlm.nih.gov/2407819"},"language":"en","primary_location":{"id":"doi:10.3109/02652049009028420","doi":"https://doi.org/10.3109/02652049009028420","is_oa":false,"landing_page_url":"https://doi.org/10.3109/02652049009028420","pdf_url":null,"source":{"id":"https://openalex.org/S160681128","display_name":"Journal of Microencapsulation","issn_l":"0265-2048","issn":["0265-2048","1464-5246"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Microencapsulation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070522156","display_name":"Henri Gin","orcid":"https://orcid.org/0000-0002-2696-6706","observed_orcids":["https://orcid.org/0000-0002-2696-6706"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"H. Gin","raw_affiliation_strings":["INSERM U 306, Bordeaux, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM U 306, Bordeaux, France","institution_ids":["https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087021332","display_name":"B. Dupuy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"B. Dupuy","raw_affiliation_strings":["Inserm U 306, 146, Rue L\u00e9o Saignat, 33076, Bordeaux C\u00e9dex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm U 306, 146, Rue L\u00e9o Saignat, 33076, Bordeaux C\u00e9dex, France","institution_ids":["https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088889406","display_name":"Josseline Caix","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"J. Caix","raw_affiliation_strings":["Inserm U 306, 146, Rue L\u00e9o Saignat, 33076, Bordeaux C\u00e9dex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm U 306, 146, Rue L\u00e9o Saignat, 33076, Bordeaux C\u00e9dex, France","institution_ids":["https://openalex.org/I154526488"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108450400","display_name":"C. Baquey","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Ch. Baquey","raw_affiliation_strings":["Inserm U 306, 146, Rue L\u00e9o Saignat, 33076, Bordeaux C\u00e9dex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm U 306, 146, Rue L\u00e9o Saignat, 33076, Bordeaux C\u00e9dex, France","institution_ids":["https://openalex.org/I154526488"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5048573986","display_name":"D. Ducassou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"D. Ducassou","raw_affiliation_strings":["Inserm U 306, 146, Rue L\u00e9o Saignat, 33076, Bordeaux C\u00e9dex, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Inserm U 306, 146, Rue L\u00e9o Saignat, 33076, Bordeaux C\u00e9dex, France","institution_ids":["https://openalex.org/I154526488"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I154526488"],"apc_list":null,"apc_paid":null,"fwci":1.5219,"has_fulltext":false,"cited_by_count":9,"citation_normalized_percentile":{"value":0.78268711,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"7","issue":"1","first_page":"17","last_page":"23"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.850600004196167,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.850600004196167,"subfield":{"id":"https://openalex.org/subfields/1313","display_name":"Molecular Medicine"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12048","display_name":"Microencapsulation and Drying Processes","score":0.09229999780654907,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.016599999740719795,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/in-vitro-diffusion","display_name":"in vitro diffusion","score":0.8730000257492065},{"id":"https://openalex.org/keywords/polyacrylamide","display_name":"polyacrylamide","score":0.8650000095367432},{"id":"https://openalex.org/keywords/microencapsulation","display_name":"microencapsulation","score":0.7770000100135803},{"id":"https://openalex.org/keywords/diffusion-coefficient","display_name":"diffusion coefficient","score":0.7110000252723694},{"id":"https://openalex.org/keywords/albumin","display_name":"albumin","score":0.9200000166893005},{"id":"https://openalex.org/keywords/radiolabeled-compounds","display_name":"radiolabeled compounds","score":0.5699999928474426},{"id":"https://openalex.org/keywords/photopolymerization","display_name":"photopolymerization","score":0.8309999704360962},{"id":"https://openalex.org/keywords/bioartificial-organs","display_name":"bioartificial organs","score":0.8709999918937683},{"id":"https://openalex.org/keywords/cell-encapsulation","display_name":"cell encapsulation","score":0.7179999947547913}],"concepts":[{"id":"https://openalex.org/C2778476535","wikidata":"https://www.wikidata.org/wiki/Q390697","display_name":"Agarose","level":2,"score":0.8361473083496094},{"id":"https://openalex.org/C80107235","wikidata":"https://www.wikidata.org/wiki/Q7162625","display_name":"Penetration (warfare)","level":2,"score":0.6493682265281677},{"id":"https://openalex.org/C2778862431","wikidata":"https://www.wikidata.org/wiki/Q416002","display_name":"Polyacrylamide","level":2,"score":0.6224709749221802},{"id":"https://openalex.org/C2776363448","wikidata":"https://www.wikidata.org/wiki/Q12008238","display_name":"Microbead (research)","level":2,"score":0.5381925702095032},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.4744594991207123},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.46636614203453064},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.43323901295661926},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3752312660217285},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.323575884103775},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12842431664466858},{"id":"https://openalex.org/C42475967","wikidata":"https://www.wikidata.org/wiki/Q194292","display_name":"Operations research","level":1,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000099166","descriptor_name":"Polyacrylamides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000180","descriptor_name":"Acrylic Resins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000418","descriptor_name":"Albumins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000911","descriptor_name":"Antibodies, Monoclonal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002214","descriptor_name":"Capsules","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004058","descriptor_name":"Diffusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007328","descriptor_name":"Insulin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010539","descriptor_name":"Permeability","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012685","descriptor_name":"Sepharose","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012974","descriptor_name":"Sodium Iodide","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3109/02652049009028420","doi":"https://doi.org/10.3109/02652049009028420","is_oa":false,"landing_page_url":"https://doi.org/10.3109/02652049009028420","pdf_url":null,"source":{"id":"https://openalex.org/S160681128","display_name":"Journal of Microencapsulation","issn_l":"0265-2048","issn":["0265-2048","1464-5246"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Microencapsulation","raw_type":"journal-article"},{"id":"pmid:2407819","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2407819","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of microencapsulation","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W561507860","https://openalex.org/W1881636865","https://openalex.org/W1967721299","https://openalex.org/W1997162214","https://openalex.org/W2004303764","https://openalex.org/W2009841111","https://openalex.org/W2012465284","https://openalex.org/W2014441095","https://openalex.org/W2031854509","https://openalex.org/W2035084866","https://openalex.org/W2038528988","https://openalex.org/W2090751710","https://openalex.org/W2090921778","https://openalex.org/W2136295921","https://openalex.org/W2142240255","https://openalex.org/W2158278740","https://openalex.org/W2161083992","https://openalex.org/W2185416357","https://openalex.org/W2507058368","https://openalex.org/W4229616858","https://openalex.org/W4251165195","https://openalex.org/W4256549760","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2168278651","https://openalex.org/W2345994250","https://openalex.org/W1887689395","https://openalex.org/W1770681837","https://openalex.org/W2118392569","https://openalex.org/W2032724256","https://openalex.org/W2015599951","https://openalex.org/W2034986638","https://openalex.org/W2015743370","https://openalex.org/W2332952510"],"abstract_inverted_index":{"125I":[0,3,5],"Sodium":[1],"iodide,":[2],"insulin,":[4],"albumin,":[6],"and":[7,16],"111indium":[8],"IGG":[9],"were":[10,27,51],"employed":[11],"to":[12],"investigate":[13],"release":[14,49],"from,":[15],"penetration":[17,64],"of":[18,31,55,65,71,76],"different":[19,48],"sized":[20],"molecules":[21],"into":[22],"agarose/polyacrylamide":[23],"microcapsules.":[24],"The":[25,38,47],"microcapsules":[26,68],"formed":[28],"by":[29],"photopolymerization":[30],"an":[32],"acrylamide":[33],"solution":[34],"round":[35],"agarose":[36],"beads.":[37],"indium-chelated":[39],"antibody":[40],"gave":[41],"a":[42],"particular":[43],"low":[44],"background":[45],"count.":[46],"times":[50],"explained":[52],"in":[53,57,62,79],"terms":[54],"differences":[56],"diffusion":[58],"coefficient.":[59],"By":[60],"retarding":[61],"vitro":[63],"antibodies,":[66],"these":[67],"could":[69],"be":[70],"value":[72],"for":[73],"the":[74],"encapsulation":[75],"living":[77],"cells":[78],"bioartificial":[80],"organs.":[81]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}