{"id":"https://openalex.org/W2034496253","doi":"https://doi.org/10.3816/sct.2007.n.018","title":"Phase II Evaluation of Desipramine for the Treatment of Hot Flashes","display_name":"Phase II Evaluation of Desipramine for the Treatment of Hot Flashes","publication_year":2007,"publication_date":"2007-09-01","ids":{"openalex":"https://openalex.org/W2034496253","doi":"https://doi.org/10.3816/sct.2007.n.018","mag":"2034496253","pmid":"https://pubmed.ncbi.nlm.nih.gov/18632520"},"language":"en","primary_location":{"id":"doi:10.3816/sct.2007.n.018","doi":"https://doi.org/10.3816/sct.2007.n.018","is_oa":false,"landing_page_url":"https://doi.org/10.3816/sct.2007.n.018","pdf_url":null,"source":{"id":"https://openalex.org/S102926519","display_name":"Supportive Cancer Therapy","issn_l":"1543-2912","issn":["1543-2912","1943-3395"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Supportive Cancer Therapy","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5033848572","display_name":"Debra L. Barton","orcid":"https://orcid.org/0000-0001-6624-3476","observed_orcids":["https://orcid.org/0000-0001-6624-3476"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]},{"id":"https://openalex.org/I4390039279","display_name":"Mayo Clinic Comprehensive Cancer Center (Minnesota)","ror":"https://ror.org/012wxv498","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4390039279"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Debra L. Barton","raw_affiliation_strings":["Comprehensive Cancer Center, Mayo Clinic College of Medicine, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Cancer Center, Mayo Clinic College of Medicine, Rochester, MN","institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I4390039279"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008767553","display_name":"Charles L. Loprinzi","orcid":"https://orcid.org/0000-0001-8044-5752","observed_orcids":["https://orcid.org/0000-0001-8044-5752"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles L. Loprinzi","raw_affiliation_strings":["Division of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Pamela Atherton","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pamela Atherton","raw_affiliation_strings":["Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110413670","display_name":"Jane M. Raymond","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800275141","display_name":"Allegheny General Hospital","ror":"https://ror.org/02gy6qp39","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1310421338","https://openalex.org/I2800275141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jane Raymond","raw_affiliation_strings":["Department of Hematology and Medical Oncology, Allegheny General Hospital, Pittsburgh, PA","Allegheny General Hospital"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Hematology and Medical Oncology, Allegheny General Hospital, Pittsburgh, PA","institution_ids":["https://openalex.org/I2800275141"]},{"raw_affiliation_string":"Allegheny General Hospital","institution_ids":["https://openalex.org/I2800275141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033825180","display_name":"Tait D. Shanafelt","orcid":"https://orcid.org/0000-0002-7106-5202","observed_orcids":["https://orcid.org/0000-0002-7106-5202"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tait Shanafelt","raw_affiliation_strings":["Division of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Medical Oncology, Mayo Clinic College of Medicine, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017291471","display_name":"Stephanie L. Hines","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stephanie Hines","raw_affiliation_strings":["Division of General Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of General Internal Medicine","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111909531","display_name":"Frances M. Palmieri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210146710","display_name":"Mayo Clinic in Florida","ror":"https://ror.org/03zzw1w08","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710"]},{"id":"https://openalex.org/I4390039324","display_name":"Mayo Clinic Comprehensive Cancer Center (Florida)","ror":"https://ror.org/007q04248","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723","https://openalex.org/I4210146710","https://openalex.org/I4390039324"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fran Palmieri","raw_affiliation_strings":["Comprehensive Cancer Center, Mayo Clinic, Jacksonville, FL","Mayo Clinic Jacksonville (FL)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Cancer Center, Mayo Clinic, Jacksonville, FL","institution_ids":["https://openalex.org/I4210146710","https://openalex.org/I4390039324"]},{"raw_affiliation_string":"Mayo Clinic Jacksonville (FL)","institution_ids":["https://openalex.org/I4210146710"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086285616","display_name":"Teresa A. Rummans","orcid":"https://orcid.org/0000-0002-7967-4766","observed_orcids":["https://orcid.org/0000-0002-7967-4766"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Teresa Rummans","raw_affiliation_strings":["Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry and Psychology, Mayo Clinic College of Medicine, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113962365","display_name":"Alex A. Adjei","orcid":"https://orcid.org/0000-0002-8039-6556","observed_orcids":["https://orcid.org/0000-0002-8039-6556"]},"institutions":[{"id":"https://openalex.org/I1292894508","display_name":"Roswell Park Comprehensive Cancer Center","ror":"https://ror.org/0499dwk57","country_code":"US","type":"facility","lineage":["https://openalex.org/I1292894508"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alex A. Adjei","raw_affiliation_strings":["Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY","Department of Medicine, Roswell Park Cancer Inst., Buffalo, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Roswell Park Cancer Institute, Buffalo, NY","institution_ids":["https://openalex.org/I1292894508"]},{"raw_affiliation_string":"Department of Medicine, Roswell Park Cancer Inst., Buffalo, NY","institution_ids":["https://openalex.org/I1292894508"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5072257104","display_name":"Jeff A. Sloan","orcid":"https://orcid.org/0000-0002-3393-2387","observed_orcids":["https://orcid.org/0000-0002-3393-2387"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeff Sloan","raw_affiliation_strings":["Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biostatistics, Mayo Clinic College of Medicine, Rochester, MN","institution_ids":["https://openalex.org/I1330342723"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5033848572"],"corresponding_institution_ids":["https://openalex.org/I1330342723","https://openalex.org/I4390039279"],"apc_list":null,"apc_paid":null,"fwci":1.2076,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":{"value":0.80911904,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"4","issue":"4","first_page":"219","last_page":"224"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10459","display_name":"Sexual function and dysfunction studies","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/desipramine","display_name":"desipramine","score":0.9980000257492065},{"id":"https://openalex.org/keywords/hot-flashes","display_name":"hot flashes","score":0.9959999918937683},{"id":"https://openalex.org/keywords/menopause","display_name":"menopause","score":0.8529999852180481},{"id":"https://openalex.org/keywords/norepinephrine-reuptake-inhibitors","display_name":"norepinephrine reuptake inhibitors","score":0.8769999742507935},{"id":"https://openalex.org/keywords/tricyclic-antidepressants","display_name":"tricyclic antidepressants","score":0.9599999785423279},{"id":"https://openalex.org/keywords/hot-flash-frequency","display_name":"hot flash frequency","score":0.7839999794960022},{"id":"https://openalex.org/keywords/drug-toxicity","display_name":"drug toxicity","score":0.7900000214576721},{"id":"https://openalex.org/keywords/insomnia","display_name":"insomnia","score":0.6779999732971191},{"id":"https://openalex.org/keywords/antidepressant-efficacy","display_name":"antidepressant efficacy","score":0.5019999742507935}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8231216073036194},{"id":"https://openalex.org/C2780250439","wikidata":"https://www.wikidata.org/wiki/Q423288","display_name":"Desipramine","level":4,"score":0.7937459945678711},{"id":"https://openalex.org/C2776128548","wikidata":"https://www.wikidata.org/wiki/Q1858291","display_name":"Hot flash","level":4,"score":0.7574756145477295},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.6991392970085144},{"id":"https://openalex.org/C2780580376","wikidata":"https://www.wikidata.org/wiki/Q186889","display_name":"Nausea","level":2,"score":0.5911457538604736},{"id":"https://openalex.org/C203092338","wikidata":"https://www.wikidata.org/wiki/Q1340863","display_name":"Clinical endpoint","level":3,"score":0.49683454632759094},{"id":"https://openalex.org/C2779657639","wikidata":"https://www.wikidata.org/wiki/Q908843","display_name":"Tricyclic antidepressant","level":4,"score":0.47453343868255615},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4031679630279541},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.38731664419174194},{"id":"https://openalex.org/C2779177272","wikidata":"https://www.wikidata.org/wiki/Q76560","display_name":"Antidepressant","level":3,"score":0.3280547857284546},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.2782256007194519},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.0},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.3816/sct.2007.n.018","doi":"https://doi.org/10.3816/sct.2007.n.018","is_oa":false,"landing_page_url":"https://doi.org/10.3816/sct.2007.n.018","pdf_url":null,"source":{"id":"https://openalex.org/S102926519","display_name":"Supportive Cancer Therapy","issn_l":"1543-2912","issn":["1543-2912","1943-3395"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Supportive Cancer Therapy","raw_type":"journal-article"},{"id":"pmid:18632520","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18632520","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Supportive cancer therapy","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.8500000238418579,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320306141","display_name":"Susan G. Komen for the Cure","ror":"https://ror.org/02nadbe75"},{"id":"https://openalex.org/F4320311413","display_name":"Susan G. Komen","ror":"https://ror.org/02nadbe75"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":23,"referenced_works":["https://openalex.org/W1479867655","https://openalex.org/W1522143645","https://openalex.org/W1593442063","https://openalex.org/W1865738444","https://openalex.org/W1891596808","https://openalex.org/W1971096261","https://openalex.org/W1973757681","https://openalex.org/W1979205504","https://openalex.org/W2022076582","https://openalex.org/W2031752049","https://openalex.org/W2032669271","https://openalex.org/W2056803338","https://openalex.org/W2062230401","https://openalex.org/W2072639223","https://openalex.org/W2082571940","https://openalex.org/W2100328118","https://openalex.org/W2107551305","https://openalex.org/W2123652060","https://openalex.org/W2129518263","https://openalex.org/W2133675074","https://openalex.org/W2149671999","https://openalex.org/W2169078759","https://openalex.org/W2313595417"],"related_works":["https://openalex.org/W1974570632","https://openalex.org/W1522143645","https://openalex.org/W4233712701","https://openalex.org/W2067750691","https://openalex.org/W2244688086","https://openalex.org/W2093978130","https://openalex.org/W2058169890","https://openalex.org/W2108930291","https://openalex.org/W2256272659","https://openalex.org/W1967925688"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":2}],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2016-06-24T00:00:00"}
