{"id":"https://openalex.org/W2034439982","doi":"https://doi.org/10.1016/j.juro.2013.01.005","title":"Image Guided Hypofractionated Radiotherapy and Quality of Life for Localized Prostate Cancer: Prospective Longitudinal Study in 337 Patients","display_name":"Image Guided Hypofractionated Radiotherapy and Quality of Life for Localized Prostate Cancer: Prospective Longitudinal Study in 337 Patients","publication_year":2013,"publication_date":"2013-01-09","ids":{"openalex":"https://openalex.org/W2034439982","doi":"https://doi.org/10.1016/j.juro.2013.01.005","mag":"2034439982","pmid":"https://pubmed.ncbi.nlm.nih.gov/23313200"},"language":"en","primary_location":{"id":"doi:10.1016/j.juro.2013.01.005","doi":"https://doi.org/10.1016/j.juro.2013.01.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.juro.2013.01.005","pdf_url":null,"source":{"id":"https://openalex.org/S30525748","display_name":"The Journal of Urology","issn_l":"0022-5347","issn":["0022-5347","1527-3792"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Urology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054413808","display_name":"Barbara Alicja Jereczek\u2010Fossa","orcid":"https://orcid.org/0000-0001-8151-3673","observed_orcids":["https://orcid.org/0000-0001-8151-3673"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Barbara A. Jereczek-Fossa","raw_affiliation_strings":["Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]},{"raw_affiliation_string":"University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023820246","display_name":"Luigi Santoro","orcid":"https://orcid.org/0000-0002-3920-4786","observed_orcids":["https://orcid.org/0000-0002-3920-4786"]},"institutions":[{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luigi Santoro","raw_affiliation_strings":["Department of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Epidemiology and Biostatistics, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012650876","display_name":"Dario Zerini","orcid":"https://orcid.org/0000-0002-9990-694X","observed_orcids":["https://orcid.org/0000-0002-9990-694X"]},"institutions":[{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Dario Zerini","raw_affiliation_strings":["Department of Radiation Oncology, European Institute of Oncology, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017477028","display_name":"Cristiana Iuliana Fodor","orcid":"https://orcid.org/0000-0003-2475-8943","observed_orcids":["https://orcid.org/0000-0003-2475-8943"]},"institutions":[{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Cristiana Fodor","raw_affiliation_strings":["Department of Radiation Oncology, European Institute of Oncology, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061232025","display_name":"Barbara Vischioni","orcid":"https://orcid.org/0000-0003-4920-2239","observed_orcids":["https://orcid.org/0000-0003-4920-2239"]},"institutions":[{"id":"https://openalex.org/I4210101051","display_name":"National Center for Oncological Hadrontherapy","ror":"https://ror.org/016fa9e26","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210101051"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Barbara Vischioni","raw_affiliation_strings":["Centro Nazionale di Adroterapia Oncologica, Pavia, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro Nazionale di Adroterapia Oncologica, Pavia, Italy","institution_ids":["https://openalex.org/I4210101051"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029417500","display_name":"Michela Dispinzieri","orcid":"https://orcid.org/0000-0003-2739-5658","observed_orcids":["https://orcid.org/0000-0003-2739-5658"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Michela Dispinzieri","raw_affiliation_strings":["Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]},{"raw_affiliation_string":"University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033765207","display_name":"Isa Bossi Zanetti","orcid":"https://orcid.org/0000-0001-6756-4749","observed_orcids":["https://orcid.org/0000-0001-6756-4749"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Isa Bossi-Zanetti","raw_affiliation_strings":["Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]},{"raw_affiliation_string":"University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085841402","display_name":"Federica Gherardi","orcid":"https://orcid.org/0000-0002-5825-1617","observed_orcids":["https://orcid.org/0000-0002-5825-1617"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Federica Gherardi","raw_affiliation_strings":["Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]},{"raw_affiliation_string":"University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001278191","display_name":"Maria Bonora","orcid":"https://orcid.org/0000-0002-8895-9165","observed_orcids":["https://orcid.org/0000-0002-8895-9165"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Maria Bonora","raw_affiliation_strings":["Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]},{"raw_affiliation_string":"University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104211147","display_name":"Mariangela Caputo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mariangela Caputo","raw_affiliation_strings":["Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]},{"raw_affiliation_string":"University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018135062","display_name":"Andrea Vavassori","orcid":"https://orcid.org/0000-0002-7965-7966","observed_orcids":["https://orcid.org/0000-0002-7965-7966"]},"institutions":[{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Vavassori","raw_affiliation_strings":["Department of Radiation Oncology, European Institute of Oncology, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035223446","display_name":"Raffaella Cambria","orcid":"https://orcid.org/0000-0001-9894-068X","observed_orcids":["https://orcid.org/0000-0001-9894-068X"]},"institutions":[{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Raffaella Cambria","raw_affiliation_strings":["Department of Medical Physics, European Institute of Oncology, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Physics, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032285191","display_name":"Cristina Garibaldi","orcid":"https://orcid.org/0000-0002-0090-1752","observed_orcids":["https://orcid.org/0000-0002-0090-1752"]},"institutions":[{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Cristina Garibaldi","raw_affiliation_strings":["Department of Medical Physics, European Institute of Oncology, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Physics, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068250967","display_name":"Federica Cattani","orcid":"https://orcid.org/0000-0002-2488-7385","observed_orcids":["https://orcid.org/0000-0002-2488-7385"]},"institutions":[{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Federica Cattani","raw_affiliation_strings":["Department of Medical Physics, European Institute of Oncology, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Physics, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113863610","display_name":"Deliu Victor Matei","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Deliu V. Matei","raw_affiliation_strings":["Department of Urology, European Institute of Oncology, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044720061","display_name":"Gennaro Musi","orcid":"https://orcid.org/0000-0003-0833-9183","observed_orcids":["https://orcid.org/0000-0003-0833-9183"]},"institutions":[{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gennaro Musi","raw_affiliation_strings":["Department of Urology, European Institute of Oncology, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047052351","display_name":"Ottavio DE COBELLI","orcid":"https://orcid.org/0000-0002-0699-8620","observed_orcids":["https://orcid.org/0000-0002-0699-8620"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ottavio De Cobelli","raw_affiliation_strings":["Department of Urology, European Institute of Oncology, Milan, Italy","University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]},{"raw_affiliation_string":"University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5053972376","display_name":"Roberto Orecchia","orcid":"https://orcid.org/0000-0003-3135-7152","observed_orcids":["https://orcid.org/0000-0003-3135-7152"]},"institutions":[{"id":"https://openalex.org/I189158943","display_name":"University of Milan","ror":"https://ror.org/00wjc7c48","country_code":"IT","type":"education","lineage":["https://openalex.org/I189158943"]},{"id":"https://openalex.org/I4210101051","display_name":"National Center for Oncological Hadrontherapy","ror":"https://ror.org/016fa9e26","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210101051"]},{"id":"https://openalex.org/I6141010","display_name":"European Institute of Oncology","ror":"https://ror.org/02vr0ne26","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210153126","https://openalex.org/I6141010"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Roberto Orecchia","raw_affiliation_strings":["Centro Nazionale di Adroterapia Oncologica, Pavia, Italy","Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","University of Milan, Milan, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centro Nazionale di Adroterapia Oncologica, Pavia, Italy","institution_ids":["https://openalex.org/I4210101051"]},{"raw_affiliation_string":"Department of Radiation Oncology, European Institute of Oncology, Milan, Italy","institution_ids":["https://openalex.org/I6141010"]},{"raw_affiliation_string":"University of Milan, Milan, Italy","institution_ids":["https://openalex.org/I189158943"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":3.952,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.93608894,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"189","issue":"6","first_page":"2099","last_page":"2103"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9595000147819519,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10124","display_name":"Prostate Cancer Diagnosis and Treatment","score":0.9595000147819519,"subfield":{"id":"https://openalex.org/subfields/2748","display_name":"Urology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10358","display_name":"Advanced Radiotherapy Techniques","score":0.03539999946951866,"subfield":{"id":"https://openalex.org/subfields/3108","display_name":"Radiation"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/hypofractionated-radiotherapy","display_name":"hypofractionated radiotherapy","score":0.8759999871253967},{"id":"https://openalex.org/keywords/image-guided-radiotherapy","display_name":"image-guided radiotherapy","score":0.9509999752044678},{"id":"https://openalex.org/keywords/localized-prostate-cancer","display_name":"localized prostate cancer","score":0.9660000205039978},{"id":"https://openalex.org/keywords/quality-of-life","display_name":"quality of life","score":0.9940000176429749},{"id":"https://openalex.org/keywords/erectile-function","display_name":"erectile function","score":0.9610000252723694},{"id":"https://openalex.org/keywords/androgen-deprivation-therapy","display_name":"androgen deprivation therapy","score":0.7319999933242798},{"id":"https://openalex.org/keywords/urinary-toxicity","display_name":"urinary toxicity","score":0.6290000081062317},{"id":"https://openalex.org/keywords/bowel-toxicity","display_name":"bowel toxicity","score":0.9929999709129333},{"id":"https://openalex.org/keywords/late-toxicity","display_name":"late toxicity","score":0.7080000042915344},{"id":"https://openalex.org/keywords/dose-escalation","display_name":"dose escalation","score":0.6209999918937683},{"id":"https://openalex.org/keywords/international-index-of-erectile-function","display_name":"International Index of Erectile Function","score":0.7360000014305115},{"id":"https://openalex.org/keywords/international-prostate-symptom-score","display_name":"International Prostate Symptom Score","score":0.9539999961853027},{"id":"https://openalex.org/keywords/eortc-qlq-pr25","display_name":"EORTC QLQ-PR25","score":0.8889999985694885},{"id":"https://openalex.org/keywords/eortc-qlq-c30","display_name":"EORTC QLQ-C30","score":0.9639999866485596}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9499497413635254},{"id":"https://openalex.org/C2780192828","wikidata":"https://www.wikidata.org/wiki/Q181257","display_name":"Prostate cancer","level":3,"score":0.7732056379318237},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.6930006146430969},{"id":"https://openalex.org/C2779951463","wikidata":"https://www.wikidata.org/wiki/Q7268788","display_name":"Quality of life (healthcare)","level":2,"score":0.6114290952682495},{"id":"https://openalex.org/C2777899217","wikidata":"https://www.wikidata.org/wiki/Q4759439","display_name":"Androgen deprivation therapy","level":4,"score":0.5899625420570374},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.5686160326004028},{"id":"https://openalex.org/C2776547966","wikidata":"https://www.wikidata.org/wiki/Q1283551","display_name":"International Prostate Symptom Score","level":5,"score":0.47906050086021423},{"id":"https://openalex.org/C2775908122","wikidata":"https://www.wikidata.org/wiki/Q3070621","display_name":"External beam radiotherapy","level":4,"score":0.45343297719955444},{"id":"https://openalex.org/C2776235491","wikidata":"https://www.wikidata.org/wiki/Q9625","display_name":"Prostate","level":3,"score":0.44931334257125854},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4176168143749237},{"id":"https://openalex.org/C2779478474","wikidata":"https://www.wikidata.org/wiki/Q446372","display_name":"Lower urinary tract symptoms","level":4,"score":0.37295806407928467},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.3556673526763916},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.3460305333137512},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.339652419090271},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003952","descriptor_name":"Diagnostic Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007558","descriptor_name":"Italy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008137","descriptor_name":"Longitudinal Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009361","descriptor_name":"Neoplasm Invasiveness","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009367","descriptor_name":"Neoplasm Staging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":true},{"descriptor_ui":"D011788","descriptor_name":"Quality of Life","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012044","descriptor_name":"Regression Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015999","descriptor_name":"Multivariate Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018570","descriptor_name":"Risk Assessment","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018579","descriptor_name":"Patient Selection","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018709","descriptor_name":"Statistics, Nonparametric","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019583","descriptor_name":"Dose Fractionation, Radiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D061089","descriptor_name":"Radiotherapy, Image-Guided","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.juro.2013.01.005","doi":"https://doi.org/10.1016/j.juro.2013.01.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.juro.2013.01.005","pdf_url":null,"source":{"id":"https://openalex.org/S30525748","display_name":"The Journal of Urology","issn_l":"0022-5347","issn":["0022-5347","1527-3792"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Urology","raw_type":"journal-article"},{"id":"pmid:23313200","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23313200","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of urology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W54334338","https://openalex.org/W1608442576","https://openalex.org/W1727008102","https://openalex.org/W1973371612","https://openalex.org/W1979237080","https://openalex.org/W1987240643","https://openalex.org/W1987512220","https://openalex.org/W1989136333","https://openalex.org/W1994076638","https://openalex.org/W1994743989","https://openalex.org/W2014239903","https://openalex.org/W2026096851","https://openalex.org/W2026641917","https://openalex.org/W2034483257","https://openalex.org/W2043945205","https://openalex.org/W2068817959","https://openalex.org/W2071365490","https://openalex.org/W2073103122","https://openalex.org/W2091013692","https://openalex.org/W2104178484","https://openalex.org/W2124530895","https://openalex.org/W2130514725","https://openalex.org/W2135136870","https://openalex.org/W2141183150","https://openalex.org/W2142991244","https://openalex.org/W2153335213","https://openalex.org/W2577042876","https://openalex.org/W2599228863","https://openalex.org/W2993539218"],"related_works":["https://openalex.org/W2901163433","https://openalex.org/W2054796636","https://openalex.org/W2906894099","https://openalex.org/W7166721262","https://openalex.org/W2133620363","https://openalex.org/W2560629381","https://openalex.org/W2226193240","https://openalex.org/W2156406561","https://openalex.org/W3197896855","https://openalex.org/W2291135801"],"abstract_inverted_index":{"PURPOSE:":[0],"We":[1],"prospectively":[2],"analyzed":[3],"quality":[4,176,194,273],"of":[5,10,18,38,53,63,100,115,150,177,195,238,272,274],"life":[6,178,196,275],"in":[7,78,143,158,172,189,248],"a":[8,16,35,259,266],"cohort":[9],"patients":[11,33,159],"with":[12,34,155,168,208,219,243,265,276],"prostate":[13,44,117,255],"cancer":[14,45,118,256],"undergoing":[15],"course":[17],"hypofractionated":[19,54,239],"image":[20,55,65,240],"guided":[21,56,66,241],"radiotherapy.":[22,234],"MATERIALS":[23],"AND":[24],"METHODS:":[25],"Between":[26],"August":[27],"2006":[28],"and":[29,89,92,107,113,121,228],"January":[30],"2011,":[31],"337":[32],"median":[36],"age":[37],"73":[39],"years":[40],"who":[41],"had":[42],"cT1-T2N0M0":[43],"were":[46],"eligible":[47],"for":[48,111,253,262],"this":[49],"prospective,":[50],"longitudinal":[51],"study":[52],"radiotherapy":[57,67,242],"(70.2":[58],"Gy/26":[59],"fractions)":[60],"using":[61],"1":[62],"3":[64],"modalities":[68,246],"(transabdominal":[69],"ultrasound,":[70],"x-ray":[71],"or":[72,182],"cone":[73],"beam":[74],"computerized":[75],"tomography)":[76],"available":[77],"our":[79,249],"radiation":[80,250],"oncology":[81,251],"department.":[82],"Patients":[83],"completed":[84],"4":[85],"questionnaires":[86],"before":[87],"treatment,":[88],"6,":[90],"12":[91],"24":[93],"months":[94],"later,":[95],"including":[96],"the":[97,131,147,180,220],"International":[98,103,148,183],"Index":[99,149],"Erectile":[101,151],"Function-5,":[102],"Prostate":[104,184],"Symptom":[105,185],"Score,":[106],"EORTC":[108],"(European":[109],"Organization":[110],"Research":[112],"Treatment":[114],"Cancer)":[116],"specific":[119],"QLQ-PR25":[120,181,190],"QLQ-C30.":[122],"RESULTS:":[123],"Patient":[124],"followup":[125,137],"was":[126,138,153,170,197],"updated":[127],"to":[128],"at":[129],"least":[130],"last":[132],"questionnaire":[133],"time":[134,156,169,209],"point.":[135],"Median":[136],"19":[139],"months.":[140],"Significant":[141],"deterioration":[142,188],"erectile":[144],"function":[145],"on":[146,179,269],"Function-5":[152],"documented":[154],"only":[157],"without":[160],"androgen":[161],"deprivation":[162],"(p":[163,199,210],"=":[164,200,211],"0.0002).":[165],"No":[166],"change":[167],"observed":[171,198],"urinary":[173,227],"symptom":[174,192],"related":[175,193],"Score.":[186],"Slight":[187],"bowel":[191,229],"0.02).":[201],"Overall":[202],"QLQ-C30":[203],"Global":[204],"Health":[205],"Status":[206],"improved":[207],"0.03).":[212],"On":[213],"univariate":[214],"analysis":[215],"it":[216],"significantly":[217],"correlated":[218],"maximum":[221],"RTOG":[222],"(Radiation":[223],"Therapy":[224],"Oncology":[225],"Group)/EORTC":[226],"late":[230],"toxicity":[231],"scores":[232],"after":[233],"CONCLUSIONS:":[235],"The":[236],"regimen":[237],"multiple":[244],"imaging":[245],"adopted":[247],"department":[252],"localized":[254],"might":[257],"be":[258],"successful":[260],"strategy":[261],"dose":[263],"escalation":[264],"limited":[267],"impact":[268],"different":[270],"aspects":[271],"time.":[277]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}