{"id":"https://openalex.org/W2034428921","doi":"https://doi.org/10.1016/j.exer.2011.08.005","title":"Immunocytochemical evidence of Tulp1-dependent outer segment protein transport pathways in photoreceptor cells","display_name":"Immunocytochemical evidence of Tulp1-dependent outer segment protein transport pathways in photoreceptor cells","publication_year":2011,"publication_date":"2011-08-16","ids":{"openalex":"https://openalex.org/W2034428921","doi":"https://doi.org/10.1016/j.exer.2011.08.005","mag":"2034428921","pmid":"https://pubmed.ncbi.nlm.nih.gov/21867699","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3221742"},"language":"en","primary_location":{"id":"doi:10.1016/j.exer.2011.08.005","doi":"https://doi.org/10.1016/j.exer.2011.08.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.exer.2011.08.005","pdf_url":null,"source":{"id":"https://openalex.org/S129637156","display_name":"Experimental Eye Research","issn_l":"0014-4835","issn":["0014-4835","1096-0007"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Eye Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3221742","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047055975","display_name":"Gregory Grossman","orcid":"https://orcid.org/0000-0003-1511-7028","observed_orcids":["https://orcid.org/0000-0003-1511-7028"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gregory H. Grossman","raw_affiliation_strings":["Department of Ophthalmic Research, i31, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmic Research, i31, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047400819","display_name":"Rao F. Watson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rao F. Watson","raw_affiliation_strings":["Department of Ophthalmic Research, i31, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA","Cleveland Clinic Foundation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmic Research, i31, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA","institution_ids":["https://openalex.org/I1316902750"]},{"raw_affiliation_string":"Cleveland Clinic Foundation","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024098227","display_name":"Gayle J. T. Pauer","orcid":"https://orcid.org/0000-0002-7173-2271","observed_orcids":["https://orcid.org/0000-0002-7173-2271"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gayle J.T. Pauer","raw_affiliation_strings":["Department of Ophthalmic Research, i31, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA","Cleveland Clinic Foundation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmic Research, i31, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA","institution_ids":["https://openalex.org/I1316902750"]},{"raw_affiliation_string":"Cleveland Clinic Foundation","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062323743","display_name":"Kathryn E. Bollinger","orcid":"https://orcid.org/0000-0002-2289-4899","observed_orcids":["https://orcid.org/0000-0002-2289-4899"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kathryn Bollinger","raw_affiliation_strings":["Department of Ophthalmic Research, i31, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA","Cleveland Clinic Foundation"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmic Research, i31, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA","institution_ids":["https://openalex.org/I1316902750"]},{"raw_affiliation_string":"Cleveland Clinic Foundation","institution_ids":["https://openalex.org/I1316902750"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057084678","display_name":"Stephanie A. Hagstrom","orcid":"https://orcid.org/0000-0003-3897-0769","observed_orcids":["https://orcid.org/0000-0003-3897-0769"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]},{"id":"https://openalex.org/I36373038","display_name":"Cleveland Clinic Lerner College of Medicine","ror":"https://ror.org/02x4b0932","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750","https://openalex.org/I36373038"]},{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Stephanie A. Hagstrom","raw_affiliation_strings":["Department of Ophthalmic Research, i31, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA","Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmic Research, i31, Cole Eye Institute, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA","institution_ids":["https://openalex.org/I1316902750"]},{"raw_affiliation_string":"Department of Ophthalmology, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, OH, USA","institution_ids":["https://openalex.org/I36373038","https://openalex.org/I58956616"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5057084678"],"corresponding_institution_ids":["https://openalex.org/I1316902750","https://openalex.org/I36373038","https://openalex.org/I58956616"],"apc_list":{"value":4010,"currency":"USD","value_usd":4010},"apc_paid":null,"fwci":3.5027,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.91436833,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"93","issue":"5","first_page":"658","last_page":"668"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.9643999934196472,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10691","display_name":"Retinal Development and Disorders","score":0.9643999934196472,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":0.029200000688433647,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11412","display_name":"Genetic and Kidney Cyst Diseases","score":0.0010000000474974513,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tulp1","display_name":"TULP1","score":0.9990000128746033},{"id":"https://openalex.org/keywords/photoreceptors","display_name":"photoreceptors","score":0.875},{"id":"https://openalex.org/keywords/retinitis-pigmentosa","display_name":"retinitis pigmentosa","score":0.8569999933242798},{"id":"https://openalex.org/keywords/guanylate-cyclase-activating-proteins","display_name":"GCAP","score":0.9110000133514404},{"id":"https://openalex.org/keywords/rhodopsin-kinase","display_name":"rhodopsin kinase","score":0.9129999876022339},{"id":"https://openalex.org/keywords/transducin","display_name":"transducin","score":0.9929999709129333},{"id":"https://openalex.org/keywords/phosphodiesterase","display_name":"phosphodiesterase","score":0.9869999885559082},{"id":"https://openalex.org/keywords/rab8","display_name":"Rab8","score":0.9490000009536743},{"id":"https://openalex.org/keywords/rab11","display_name":"Rab11","score":1.0},{"id":"https://openalex.org/keywords/connecting-cilium","display_name":"connecting cilium","score":0.9110000133514404},{"id":"https://openalex.org/keywords/membrane-protein-transport","display_name":"membrane protein transport","score":0.46299999952316284}],"concepts":[{"id":"https://openalex.org/C202033177","wikidata":"https://www.wikidata.org/wiki/Q423107","display_name":"Rhodopsin","level":3,"score":0.7251260280609131},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6384782791137695},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5514911413192749},{"id":"https://openalex.org/C57581600","wikidata":"https://www.wikidata.org/wiki/Q2449730","display_name":"Transport protein","level":2,"score":0.48015183210372925},{"id":"https://openalex.org/C149574991","wikidata":"https://www.wikidata.org/wiki/Q420428","display_name":"Transducin","level":4,"score":0.4793856143951416},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3724991977214813},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.35714638233184814},{"id":"https://openalex.org/C2780827179","wikidata":"https://www.wikidata.org/wiki/Q422001","display_name":"Retinal","level":2,"score":0.1634020209312439}],"mesh":[{"descriptor_ui":"D000221","descriptor_name":"Adaptation, Ocular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005136","descriptor_name":"Eye Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005136","descriptor_name":"Eye Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006162","descriptor_name":"Guanylate Cyclase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015293","descriptor_name":"Transducin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019084","descriptor_name":"Fluorescent Antibody Technique, Indirect","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019393","descriptor_name":"Arrestin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D021381","descriptor_name":"Protein Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051604","descriptor_name":"Guanylate Cyclase-Activating Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051606","descriptor_name":"G-Protein-Coupled Receptor Kinase 1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D055214","descriptor_name":"Retinal Photoreceptor Cell Outer Segment","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.exer.2011.08.005","doi":"https://doi.org/10.1016/j.exer.2011.08.005","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.exer.2011.08.005","pdf_url":null,"source":{"id":"https://openalex.org/S129637156","display_name":"Experimental Eye Research","issn_l":"0014-4835","issn":["0014-4835","1096-0007"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental Eye Research","raw_type":"journal-article"},{"id":"pmid:21867699","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21867699","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Experimental eye research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3221742","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3221742","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Exp Eye Res","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3221742","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3221742","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Exp Eye Res","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G7380105499","display_name":"Vision Research Infrastructure Development Grant","funder_award_id":"R24EY015638","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"},{"id":"https://openalex.org/G8007868103","display_name":"The Role of TULP1 in Photoreceptor Cells","funder_award_id":"R01EY016072","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320306948","display_name":"Fight for Sight","ror":"https://ror.org/01j378a47"},{"id":"https://openalex.org/F4320308284","display_name":"Prevent Blindness Ohio","ror":"https://ror.org/029tzwe02"},{"id":"https://openalex.org/F4320312393","display_name":"Hope For Vision","ror":"https://ror.org/02yqjk243"},{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":83,"referenced_works":["https://openalex.org/W49951449","https://openalex.org/W77228969","https://openalex.org/W94952055","https://openalex.org/W106607304","https://openalex.org/W192956045","https://openalex.org/W204214636","https://openalex.org/W1536091221","https://openalex.org/W1547636063","https://openalex.org/W1555546746","https://openalex.org/W1556819342","https://openalex.org/W1565304364","https://openalex.org/W1575023142","https://openalex.org/W1590224423","https://openalex.org/W1641104439","https://openalex.org/W1914786390","https://openalex.org/W1964573575","https://openalex.org/W1965182896","https://openalex.org/W1965185652","https://openalex.org/W1967993225","https://openalex.org/W1968594982","https://openalex.org/W1968686595","https://openalex.org/W1975715824","https://openalex.org/W1985729465","https://openalex.org/W1986779023","https://openalex.org/W1993618816","https://openalex.org/W1994150214","https://openalex.org/W1996743997","https://openalex.org/W1997301669","https://openalex.org/W1999010404","https://openalex.org/W2000077668","https://openalex.org/W2001040160","https://openalex.org/W2007127198","https://openalex.org/W2011759878","https://openalex.org/W2015739924","https://openalex.org/W2026743321","https://openalex.org/W2026820540","https://openalex.org/W2029485967","https://openalex.org/W2029862966","https://openalex.org/W2029895192","https://openalex.org/W2031682891","https://openalex.org/W2032338309","https://openalex.org/W2033231791","https://openalex.org/W2033852655","https://openalex.org/W2035322249","https://openalex.org/W2037709017","https://openalex.org/W2037709331","https://openalex.org/W2038206466","https://openalex.org/W2042465195","https://openalex.org/W2045907809","https://openalex.org/W2052033407","https://openalex.org/W2066594110","https://openalex.org/W2075398040","https://openalex.org/W2076294810","https://openalex.org/W2076644311","https://openalex.org/W2077995395","https://openalex.org/W2086493498","https://openalex.org/W2092165851","https://openalex.org/W2093156779","https://openalex.org/W2093710097","https://openalex.org/W2094405968","https://openalex.org/W2098473847","https://openalex.org/W2101436175","https://openalex.org/W2112737360","https://openalex.org/W2117198084","https://openalex.org/W2134168057","https://openalex.org/W2140128594","https://openalex.org/W2141160298","https://openalex.org/W2142523086","https://openalex.org/W2143938161","https://openalex.org/W2143952717","https://openalex.org/W2146397440","https://openalex.org/W2156540321","https://openalex.org/W2161475219","https://openalex.org/W2167652900","https://openalex.org/W2167860692","https://openalex.org/W2184527515","https://openalex.org/W2186674126","https://openalex.org/W6632835703","https://openalex.org/W6633235316","https://openalex.org/W6633323811","https://openalex.org/W6633887798","https://openalex.org/W6635187720","https://openalex.org/W6676691504"],"related_works":["https://openalex.org/W1994150214","https://openalex.org/W1493256932","https://openalex.org/W1555546746","https://openalex.org/W1556819342","https://openalex.org/W7095974161","https://openalex.org/W7097332798","https://openalex.org/W256671188","https://openalex.org/W2341190600","https://openalex.org/W3185352117","https://openalex.org/W160726623"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}