{"id":"https://openalex.org/W2034421611","doi":"https://doi.org/10.1016/j.clinre.2015.02.010","title":"Impact of hepatic immunoreactivity of angiotensin-converting enzyme 2 on liver fibrosis due to non-alcoholic steatohepatitis","display_name":"Impact of hepatic immunoreactivity of angiotensin-converting enzyme 2 on liver fibrosis due to non-alcoholic steatohepatitis","publication_year":2015,"publication_date":"2015-04-15","ids":{"openalex":"https://openalex.org/W2034421611","doi":"https://doi.org/10.1016/j.clinre.2015.02.010","mag":"2034421611","pmid":"https://pubmed.ncbi.nlm.nih.gov/25887687"},"language":"en","primary_location":{"id":"doi:10.1016/j.clinre.2015.02.010","doi":"https://doi.org/10.1016/j.clinre.2015.02.010","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.clinre.2015.02.010","pdf_url":null,"source":{"id":"https://openalex.org/S2481910785","display_name":"Clinics and Research in Hepatology and Gastroenterology","issn_l":"2210-7401","issn":["2210-7401","2210-741X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinics and Research in Hepatology and Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075041374","display_name":"Mustafa Cengiz","orcid":"https://orcid.org/0000-0001-7465-1162","observed_orcids":["https://orcid.org/0000-0001-7465-1162"]},"institutions":[{"id":"https://openalex.org/I4210108612","display_name":"Ankara Onkoloji E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/01r05t925","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4210108612"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Mustafa Cengiz","raw_affiliation_strings":["Dr. A.Y. Ankara Oncology Training and Research Hospital, Department of Gastroenterology, 06200 Ankara, Turkey. Electronic address: drmustafacen@gmail.com","Dr. A.Y. Ankara Oncology Training and Research Hospital, Department of Gastroenterology, 06200 Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dr. A.Y. Ankara Oncology Training and Research Hospital, Department of Gastroenterology, 06200 Ankara, Turkey. Electronic address: drmustafacen@gmail.com","institution_ids":["https://openalex.org/I4210108612"]},{"raw_affiliation_string":"Dr. A.Y. Ankara Oncology Training and Research Hospital, Department of Gastroenterology, 06200 Ankara, Turkey","institution_ids":["https://openalex.org/I4210108612"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061962405","display_name":"Seren \u00d6zenirler","orcid":"https://orcid.org/0000-0003-1801-5844","observed_orcids":["https://orcid.org/0000-0003-1801-5844"]},"institutions":[{"id":"https://openalex.org/I95634034","display_name":"Gazi University","ror":"https://ror.org/054xkpr46","country_code":"TR","type":"education","lineage":["https://openalex.org/I95634034"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Seren Ozenirler","raw_affiliation_strings":["Gazi University Faculty of Medicine, Department of Gastroenterology, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gazi University Faculty of Medicine, Department of Gastroenterology, Ankara, Turkey","institution_ids":["https://openalex.org/I95634034"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110259325","display_name":"G\u00fcldal Y\u0131lmaz","orcid":"https://orcid.org/0000-0002-0307-3075","observed_orcids":["https://orcid.org/0000-0002-0307-3075"]},"institutions":[{"id":"https://openalex.org/I95634034","display_name":"Gazi University","ror":"https://ror.org/054xkpr46","country_code":"TR","type":"education","lineage":["https://openalex.org/I95634034"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Guldal Y\u0131lmaz","raw_affiliation_strings":["Gazi University Faculty of Medicine, Department of Pathology, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Gazi University Faculty of Medicine, Department of Pathology, Ankara, Turkey","institution_ids":["https://openalex.org/I95634034"]}]},{"author_position":"last","author":{"id":null,"display_name":"Gulbanu Erkan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165891364","display_name":"Ufuk University","ror":"https://ror.org/04dj8ng22","country_code":"TR","type":"education","lineage":["https://openalex.org/I165891364"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Gulbanu Erkan","raw_affiliation_strings":["Ufuk University Faculty of Medicine, Department of Gastroenterology, Ankara, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ufuk University Faculty of Medicine, Department of Gastroenterology, Ankara, Turkey","institution_ids":["https://openalex.org/I165891364"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5075041374"],"corresponding_institution_ids":["https://openalex.org/I4210108612"],"apc_list":{"value":3260,"currency":"USD","value_usd":3260},"apc_paid":null,"fwci":0.3238,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.59050035,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"39","issue":"6","first_page":"692","last_page":"698"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10351","display_name":"Liver Disease Diagnosis and Treatment","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10966","display_name":"Liver physiology and pathology","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11834","display_name":"Liver Diseases and Immunity","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/angiotensin-converting-enzyme-2","display_name":"angiotensin-converting enzyme 2","score":0.9940000176429749},{"id":"https://openalex.org/keywords/non-alcoholic-steatohepatitis","display_name":"nonalcoholic steatohepatitis","score":0.8859999775886536},{"id":"https://openalex.org/keywords/liver-fibrosis","display_name":"liver fibrosis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/fibrosis-progression","display_name":"fibrosis progression","score":0.8529999852180481},{"id":"https://openalex.org/keywords/fibrosis-score","display_name":"fibrosis score","score":0.6710000038146973},{"id":"https://openalex.org/keywords/bridging-fibrosis","display_name":"bridging fibrosis","score":0.8960000276565552},{"id":"https://openalex.org/keywords/predictive-biomarkers","display_name":"predictive biomarkers","score":0.4309999942779541}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8232707977294922},{"id":"https://openalex.org/C2780559512","wikidata":"https://www.wikidata.org/wiki/Q605709","display_name":"Fibrosis","level":2,"score":0.7885776162147522},{"id":"https://openalex.org/C2779478299","wikidata":"https://www.wikidata.org/wiki/Q2335423","display_name":"Steatohepatitis","level":4,"score":0.746828556060791},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.7184813618659973},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.7121326923370361},{"id":"https://openalex.org/C2993667909","wikidata":"https://www.wikidata.org/wiki/Q147778","display_name":"Hepatic fibrosis","level":3,"score":0.6270742416381836},{"id":"https://openalex.org/C144301174","wikidata":"https://www.wikidata.org/wiki/Q7893852","display_name":"Univariate analysis","level":3,"score":0.590134859085083},{"id":"https://openalex.org/C2777766500","wikidata":"https://www.wikidata.org/wiki/Q360841","display_name":"Liver biopsy","level":3,"score":0.5865868926048279},{"id":"https://openalex.org/C156957248","wikidata":"https://www.wikidata.org/wiki/Q1862216","display_name":"Odds ratio","level":2,"score":0.5376729965209961},{"id":"https://openalex.org/C2778772119","wikidata":"https://www.wikidata.org/wiki/Q6058862","display_name":"Fatty liver","level":3,"score":0.4542478024959564},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.43889862298965454},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4351688623428345},{"id":"https://openalex.org/C38180746","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate analysis","level":2,"score":0.30544397234916687},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.07885903120040894}],"mesh":[{"descriptor_ui":"D000085962","descriptor_name":"Angiotensin-Converting Enzyme 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007703","descriptor_name":"Peptidyl-Dipeptidase A","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D008103","descriptor_name":"Liver Cirrhosis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D065626","descriptor_name":"Non-alcoholic Fatty Liver Disease","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.clinre.2015.02.010","doi":"https://doi.org/10.1016/j.clinre.2015.02.010","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.clinre.2015.02.010","pdf_url":null,"source":{"id":"https://openalex.org/S2481910785","display_name":"Clinics and Research in Hepatology and Gastroenterology","issn_l":"2210-7401","issn":["2210-7401","2210-741X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinics and Research in Hepatology and Gastroenterology","raw_type":"journal-article"},{"id":"pmid:25887687","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25887687","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinics and research in hepatology and gastroenterology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9763000011444092,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W203043366","https://openalex.org/W1607046827","https://openalex.org/W1969638471","https://openalex.org/W1972113011","https://openalex.org/W1972709924","https://openalex.org/W1977563077","https://openalex.org/W1989404519","https://openalex.org/W1996664856","https://openalex.org/W1998618567","https://openalex.org/W2000040025","https://openalex.org/W2004840558","https://openalex.org/W2014363167","https://openalex.org/W2025672718","https://openalex.org/W2041586213","https://openalex.org/W2042858449","https://openalex.org/W2044710035","https://openalex.org/W2052879115","https://openalex.org/W2060204625","https://openalex.org/W2065612971","https://openalex.org/W2067740038","https://openalex.org/W2070761972","https://openalex.org/W2087829753","https://openalex.org/W2102118018","https://openalex.org/W2108312009","https://openalex.org/W2116404316","https://openalex.org/W2132520424","https://openalex.org/W2135356216","https://openalex.org/W2144178804","https://openalex.org/W2147515973","https://openalex.org/W2158515483","https://openalex.org/W2160887608","https://openalex.org/W2161096403","https://openalex.org/W2165313963","https://openalex.org/W2166360182","https://openalex.org/W6642496413"],"related_works":["https://openalex.org/W2313367923","https://openalex.org/W2158515483","https://openalex.org/W2777804325","https://openalex.org/W3012439906","https://openalex.org/W2612037457","https://openalex.org/W2406631875","https://openalex.org/W2612460067","https://openalex.org/W2795827635","https://openalex.org/W2006404757","https://openalex.org/W2052144118"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}