{"id":"https://openalex.org/W2033859589","doi":"https://doi.org/10.1136/gut.11.7.588","title":"Fibrinolysis in colonic disease","display_name":"Fibrinolysis in colonic disease","publication_year":1970,"publication_date":"1970-07-01","ids":{"openalex":"https://openalex.org/W2033859589","doi":"https://doi.org/10.1136/gut.11.7.588","mag":"2033859589","pmid":"https://pubmed.ncbi.nlm.nih.gov/5452047","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1553073"},"language":"en","primary_location":{"id":"doi:10.1136/gut.11.7.588","doi":"https://doi.org/10.1136/gut.11.7.588","is_oa":true,"landing_page_url":"https://doi.org/10.1136/gut.11.7.588","pdf_url":"https://gut.bmj.com/content/gutjnl/11/7/588.full.pdf","source":{"id":"https://openalex.org/S3251770","display_name":"Gut","issn_l":"0017-5749","issn":["0017-5749","1468-3288"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://gut.bmj.com/content/gutjnl/11/7/588.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110084391","display_name":"Caroline Swan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802226719","display_name":"Birmingham General Hospital","ror":"https://ror.org/04g2hhm55","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802226719"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"C. H. J. Swan","raw_affiliation_strings":["the Nutritional and Intestinal Unit , The General Hospital , Birmingham","From the Nutritional and Intestinal Unit, The General Hospital, Birmingham"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Nutritional and Intestinal Unit , The General Hospital , Birmingham","institution_ids":["https://openalex.org/I2802226719"]},{"raw_affiliation_string":"From the Nutritional and Intestinal Unit, The General Hospital, Birmingham","institution_ids":["https://openalex.org/I2802226719"]}]},{"author_position":"middle","author":{"id":null,"display_name":"J. Alexander Williams","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802226719","display_name":"Birmingham General Hospital","ror":"https://ror.org/04g2hhm55","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802226719"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"J. Alexander Williams","raw_affiliation_strings":["the Nutritional and Intestinal Unit , The General Hospital , Birmingham","From the Nutritional and Intestinal Unit, The General Hospital, Birmingham"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"the Nutritional and Intestinal Unit , The General Hospital , Birmingham","institution_ids":["https://openalex.org/I2802226719"]},{"raw_affiliation_string":"From the Nutritional and Intestinal Unit, The General Hospital, Birmingham","institution_ids":["https://openalex.org/I2802226719"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024513501","display_name":"W. T. Cooke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802226719","display_name":"Birmingham General Hospital","ror":"https://ror.org/04g2hhm55","country_code":"GB","type":"healthcare","lineage":["https://openalex.org/I2802226719"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"W. T. Cooke","raw_affiliation_strings":["From the Nutritional and Intestinal Unit, The General Hospital, Birmingham"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Nutritional and Intestinal Unit, The General Hospital, Birmingham","institution_ids":["https://openalex.org/I2802226719"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I2802226719"],"apc_list":null,"apc_paid":null,"fwci":1.0953,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.7739186,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"11","issue":"7","first_page":"588","last_page":"591"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.6865000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.6865000128746033,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11721","display_name":"Blood properties and coagulation","score":0.2320999950170517,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.05990000069141388,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fibrinolysis","display_name":"fibrinolysis","score":0.9959999918937683},{"id":"https://openalex.org/keywords/colonic-diseases","display_name":"colonic diseases","score":0.8230000138282776},{"id":"https://openalex.org/keywords/ulcerative-colitis","display_name":"ulcerative colitis","score":0.984000027179718},{"id":"https://openalex.org/keywords/crohn-s-colitis","display_name":"Crohn's colitis","score":0.9430000185966492},{"id":"https://openalex.org/keywords/colon-cancer","display_name":"colon cancer","score":0.9350000023841858},{"id":"https://openalex.org/keywords/diverticulosis","display_name":"diverticulosis","score":0.9850000143051147},{"id":"https://openalex.org/keywords/venous-blood","display_name":"venous blood","score":0.7680000066757202},{"id":"https://openalex.org/keywords/arterial-blood","display_name":"arterial blood","score":0.9620000123977661},{"id":"https://openalex.org/keywords/bleeding-complications","display_name":"bleeding complications","score":0.5099999904632568}],"concepts":[{"id":"https://openalex.org/C2776825266","wikidata":"https://www.wikidata.org/wiki/Q1410794","display_name":"Fibrinolysis","level":2,"score":0.8408238291740417},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5881925821304321},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4339568614959717},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4167203903198242},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4110887050628662}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001780","descriptor_name":"Blood Coagulation Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D003093","descriptor_name":"Colitis, Ulcerative","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003093","descriptor_name":"Colitis, Ulcerative","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003110","descriptor_name":"Colonic Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D003424","descriptor_name":"Crohn Disease","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003424","descriptor_name":"Crohn Disease","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D004241","descriptor_name":"Diverticulum, Colon","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D004241","descriptor_name":"Diverticulum, Colon","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005342","descriptor_name":"Fibrinolysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011183","descriptor_name":"Postoperative Complications","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013924","descriptor_name":"Thrombophlebitis","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1136/gut.11.7.588","doi":"https://doi.org/10.1136/gut.11.7.588","is_oa":true,"landing_page_url":"https://doi.org/10.1136/gut.11.7.588","pdf_url":"https://gut.bmj.com/content/gutjnl/11/7/588.full.pdf","source":{"id":"https://openalex.org/S3251770","display_name":"Gut","issn_l":"0017-5749","issn":["0017-5749","1468-3288"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1553073","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1553073","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut","raw_type":"Text"},{"id":"pmid:5452047","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5452047","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1136/gut.11.7.588","doi":"https://doi.org/10.1136/gut.11.7.588","is_oa":true,"landing_page_url":"https://doi.org/10.1136/gut.11.7.588","pdf_url":"https://gut.bmj.com/content/gutjnl/11/7/588.full.pdf","source":{"id":"https://openalex.org/S3251770","display_name":"Gut","issn_l":"0017-5749","issn":["0017-5749","1468-3288"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319945","host_organization_name":"BMJ","host_organization_lineage":["https://openalex.org/P4310319945"],"host_organization_lineage_names":["BMJ"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Gut","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2033859589.pdf","grobid_xml":"https://content.openalex.org/works/W2033859589.grobid-xml"},"referenced_works_count":20,"referenced_works":["https://openalex.org/W1968775158","https://openalex.org/W1969102790","https://openalex.org/W1970027994","https://openalex.org/W1975867290","https://openalex.org/W1990995143","https://openalex.org/W1997194136","https://openalex.org/W2008642958","https://openalex.org/W2014594737","https://openalex.org/W2016287070","https://openalex.org/W2023861957","https://openalex.org/W2040162023","https://openalex.org/W2053739693","https://openalex.org/W2088985644","https://openalex.org/W2340360504","https://openalex.org/W2396772007","https://openalex.org/W2398706287","https://openalex.org/W2399364858","https://openalex.org/W2400695267","https://openalex.org/W2443680352","https://openalex.org/W4248744072"],"related_works":["https://openalex.org/W2042037868","https://openalex.org/W2040162023","https://openalex.org/W2494737807","https://openalex.org/W2052182056","https://openalex.org/W1986008085","https://openalex.org/W2413069005","https://openalex.org/W2015374530","https://openalex.org/W2035656939","https://openalex.org/W2082735565","https://openalex.org/W2079724171"],"abstract_inverted_index":{"Fibrinolytic":[0],"activity":[1,49,70,82],"of":[2,26,62,86],"colic":[3,51],"venous":[4,52,80],"and":[5,22,83],"arterial":[6],"blood":[7,37,53],"has":[8],"been":[9],"studied":[10],"at":[11],"laparotomy":[12],"in":[13,50],"18":[14],"patients":[15,28],"with":[16,24,29,68],"ulcerative":[17],"colitis":[18,21],"or":[19,32,64],"Crohn's":[20],"compared":[23,67],"that":[25],"17":[27],"colonic":[30],"carcinoma":[31],"diverticulosis.":[33],"Using":[34],"the":[35,47,55,59,71,84],"dilute":[36],"clot":[38],"lysis":[39],"time":[40],"technique,":[41],"no":[42],"difference":[43],"was":[44],"detected":[45],"between":[46,76],"fibrinolytic":[48,69,81],"from":[54],"two":[56],"groups.":[57],"When":[58],"clinical":[60],"complications":[61],"bleeding":[63],"thrombosis":[65],"are":[66],"only":[72],"important":[73],"association":[74],"is":[75],"a":[77],"low":[78],"peripheral":[79],"occurrence":[85],"postoperative":[87],"thrombo-embolic":[88],"complications.":[89]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}