{"id":"https://openalex.org/W2033859288","doi":"https://doi.org/10.1007/s10856-010-3992-x","title":"In vitro cytocompatibility evaluation of a thermoresponsive NIPAAm-MMA copolymeric surface using L929 cells","display_name":"In vitro cytocompatibility evaluation of a thermoresponsive NIPAAm-MMA copolymeric surface using L929 cells","publication_year":2010,"publication_date":"2010-01-21","ids":{"openalex":"https://openalex.org/W2033859288","doi":"https://doi.org/10.1007/s10856-010-3992-x","mag":"2033859288","pmid":"https://pubmed.ncbi.nlm.nih.gov/20094902"},"language":"en","primary_location":{"id":"doi:10.1007/s10856-010-3992-x","doi":"https://doi.org/10.1007/s10856-010-3992-x","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10856-010-3992-x","pdf_url":null,"source":{"id":"https://openalex.org/S166781098","display_name":"Journal of Materials Science Materials in Medicine","issn_l":"0957-4530","issn":["0957-4530","1573-4838"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Materials Science: Materials in Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5010821672","display_name":"Viji Mary Varghese","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800373951","display_name":"Sree Chitra Thirunal Institute for Medical Sciences and Technology","ror":"https://ror.org/05757k612","country_code":"IN","type":"facility","lineage":["https://openalex.org/I2800373951"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Viji Mary Varghese","raw_affiliation_strings":["Tissue Culture Laboratory, Division of Implant Biology, Biomedical Technology Wing, Sree Chithra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tissue Culture Laboratory, Division of Implant Biology, Biomedical Technology Wing, Sree Chithra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India","institution_ids":["https://openalex.org/I2800373951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102299964","display_name":"Vidya Raj","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800373951","display_name":"Sree Chitra Thirunal Institute for Medical Sciences and Technology","ror":"https://ror.org/05757k612","country_code":"IN","type":"facility","lineage":["https://openalex.org/I2800373951"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Vidya Raj","raw_affiliation_strings":["Laboratory for Polymer Analysis, Biomedical Technology Wing, Sree Chithra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Polymer Analysis, Biomedical Technology Wing, Sree Chithra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India","institution_ids":["https://openalex.org/I2800373951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108765125","display_name":"K. Sreenivasan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800373951","display_name":"Sree Chitra Thirunal Institute for Medical Sciences and Technology","ror":"https://ror.org/05757k612","country_code":"IN","type":"facility","lineage":["https://openalex.org/I2800373951"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"K. Sreenivasan","raw_affiliation_strings":["Laboratory for Polymer Analysis, Biomedical Technology Wing, Sree Chithra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory for Polymer Analysis, Biomedical Technology Wing, Sree Chithra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India","institution_ids":["https://openalex.org/I2800373951"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111663316","display_name":"T. V. Kumary","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800373951","display_name":"Sree Chitra Thirunal Institute for Medical Sciences and Technology","ror":"https://ror.org/05757k612","country_code":"IN","type":"facility","lineage":["https://openalex.org/I2800373951"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"T. V. Kumary","raw_affiliation_strings":["Tissue Culture Laboratory, Division of Implant Biology, Biomedical Technology Wing, Sree Chithra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tissue Culture Laboratory, Division of Implant Biology, Biomedical Technology Wing, Sree Chithra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India","institution_ids":["https://openalex.org/I2800373951"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5111663316"],"corresponding_institution_ids":["https://openalex.org/I2800373951"],"apc_list":{"value":2590,"currency":"USD","value_usd":2590},"apc_paid":null,"fwci":0.6951,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.62078929,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"21","issue":"5","first_page":"1631","last_page":"1639"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10343","display_name":"Hydrogels: synthesis, properties, applications","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10859","display_name":"Polymer Surface Interaction Studies","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/n-isopropylacrylamide","display_name":"N-isopropylacrylamide","score":0.9520000219345093},{"id":"https://openalex.org/keywords/methyl-methacrylate","display_name":"methyl methacrylate","score":0.984000027179718},{"id":"https://openalex.org/keywords/thermoresponsive-polymers","display_name":"thermoresponsive polymers","score":0.8999999761581421},{"id":"https://openalex.org/keywords/cytocompatibility","display_name":"cytocompatibility","score":0.8980000019073486},{"id":"https://openalex.org/keywords/l929-fibroblasts","display_name":"L929 fibroblasts","score":0.9559999704360962},{"id":"https://openalex.org/keywords/lower-critical-solution-temperature","display_name":"lower critical solution temperature","score":0.9539999961853027},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.8539999723434448},{"id":"https://openalex.org/keywords/cell-viability","display_name":"cell viability","score":0.7559999823570251},{"id":"https://openalex.org/keywords/cytoskeleton-organization","display_name":"cytoskeletal organization","score":0.7620000243186951},{"id":"https://openalex.org/keywords/tissue-engineering","display_name":"tissue engineering","score":0.46799999475479126}],"concepts":[{"id":"https://openalex.org/C15920480","wikidata":"https://www.wikidata.org/wiki/Q421281","display_name":"Copolymer","level":3,"score":0.907511830329895},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.6318731307983398},{"id":"https://openalex.org/C2777935641","wikidata":"https://www.wikidata.org/wiki/Q382897","display_name":"Methyl methacrylate","level":4,"score":0.5569601655006409},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5516690015792847},{"id":"https://openalex.org/C188027245","wikidata":"https://www.wikidata.org/wiki/Q750446","display_name":"Polymer chemistry","level":1,"score":0.5228248834609985},{"id":"https://openalex.org/C2780381497","wikidata":"https://www.wikidata.org/wiki/Q463418","display_name":"Fibroblast","level":3,"score":0.50981205701828},{"id":"https://openalex.org/C2777922577","wikidata":"https://www.wikidata.org/wiki/Q146243","display_name":"Polystyrene","level":3,"score":0.4910318851470947},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4903991222381592},{"id":"https://openalex.org/C132050475","wikidata":"https://www.wikidata.org/wiki/Q736232","display_name":"Methacrylate","level":4,"score":0.4841673970222473},{"id":"https://openalex.org/C89429830","wikidata":"https://www.wikidata.org/wiki/Q735710","display_name":"Scaffold","level":2,"score":0.47523167729377747},{"id":"https://openalex.org/C74864618","wikidata":"https://www.wikidata.org/wiki/Q2332446","display_name":"Staining","level":2,"score":0.42941582202911377},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.427026629447937},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.40257352590560913},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.398425430059433},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3920029103755951},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.35380423069000244},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.3376705050468445},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.13058894872665405},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13052579760551453},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000178","descriptor_name":"Acrylamides","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001672","descriptor_name":"Biocompatible Materials","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D002477","descriptor_name":"Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007739","descriptor_name":"L Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014867","descriptor_name":"Water","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D020366","descriptor_name":"Methylmethacrylate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023822","descriptor_name":"Tissue Engineering","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/s10856-010-3992-x","doi":"https://doi.org/10.1007/s10856-010-3992-x","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10856-010-3992-x","pdf_url":null,"source":{"id":"https://openalex.org/S166781098","display_name":"Journal of Materials Science Materials in Medicine","issn_l":"0957-4530","issn":["0957-4530","1573-4838"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Materials Science: Materials in Medicine","raw_type":"journal-article"},{"id":"pmid:20094902","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20094902","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of materials science. Materials in medicine","raw_type":"Evaluation Study"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W1964066906","https://openalex.org/W1977040433","https://openalex.org/W1980780439","https://openalex.org/W1983564086","https://openalex.org/W1990612468","https://openalex.org/W1999989552","https://openalex.org/W2004209532","https://openalex.org/W2008834718","https://openalex.org/W2012755388","https://openalex.org/W2016905804","https://openalex.org/W2017904896","https://openalex.org/W2023041592","https://openalex.org/W2025423794","https://openalex.org/W2037464135","https://openalex.org/W2039737560","https://openalex.org/W2040341666","https://openalex.org/W2047015253","https://openalex.org/W2055454490","https://openalex.org/W2057098417","https://openalex.org/W2062532423","https://openalex.org/W2067441002","https://openalex.org/W2085904428","https://openalex.org/W2115016737","https://openalex.org/W2128984725","https://openalex.org/W2333364958","https://openalex.org/W2435887348","https://openalex.org/W2747310579","https://openalex.org/W4235209420"],"related_works":["https://openalex.org/W2521937840","https://openalex.org/W2088489057","https://openalex.org/W2018134226","https://openalex.org/W2026734879","https://openalex.org/W1970754295","https://openalex.org/W2740138799","https://openalex.org/W2017384460","https://openalex.org/W2022672474","https://openalex.org/W2025423794","https://openalex.org/W2368601435"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}