{"id":"https://openalex.org/W2033720095","doi":"https://doi.org/10.1021/ac60358a074","title":"Quantitative metabolic profiling of urinary organic acids by gas chromatography-mass spectrometry. Comparison of isolation methods","display_name":"Quantitative metabolic profiling of urinary organic acids by gas chromatography-mass spectrometry. Comparison of isolation methods","publication_year":1975,"publication_date":"1975-07-01","ids":{"openalex":"https://openalex.org/W2033720095","doi":"https://doi.org/10.1021/ac60358a074","mag":"2033720095","pmid":"https://pubmed.ncbi.nlm.nih.gov/1147254"},"language":"en","primary_location":{"id":"doi:10.1021/ac60358a074","doi":"https://doi.org/10.1021/ac60358a074","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ac60358a074","pdf_url":null,"source":{"id":"https://openalex.org/S191963794","display_name":"Analytical Chemistry","issn_l":"0003-2700","issn":["0003-2700","1520-6882"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"John A. Thompson","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"John A. Thompson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111562890","display_name":"Sanford P. Markey","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sanford P. Markey","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":13.505,"has_fulltext":false,"cited_by_count":149,"citation_normalized_percentile":{"value":0.99477807,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"47","issue":"8","first_page":"1313","last_page":"1321"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.46219998598098755,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.46219998598098755,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.43380001187324524,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography","score":0.04960000142455101,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/urinary-organic-acids","display_name":"urinary organic acids","score":0.9990000128746033},{"id":"https://openalex.org/keywords/metabolic-profiling","display_name":"metabolite profiling","score":0.9169999957084656},{"id":"https://openalex.org/keywords/quantitative-analysis","display_name":"quantitative analysis","score":0.4819999933242798},{"id":"https://openalex.org/keywords/gas-chromatography-mass-spectrometry","display_name":"gas chromatography-mass spectrometry","score":0.8130000233650208}],"concepts":[{"id":"https://openalex.org/C187191949","wikidata":"https://www.wikidata.org/wiki/Q1138496","display_name":"Profiling (computer programming)","level":2,"score":0.5373737812042236},{"id":"https://openalex.org/C2778407487","wikidata":"https://www.wikidata.org/wiki/Q14565201","display_name":"Altmetrics","level":2,"score":0.4979696273803711},{"id":"https://openalex.org/C2778805511","wikidata":"https://www.wikidata.org/wiki/Q1713","display_name":"Citation","level":2,"score":0.49744513630867004},{"id":"https://openalex.org/C23123220","wikidata":"https://www.wikidata.org/wiki/Q816826","display_name":"Information retrieval","level":1,"score":0.47775998711586},{"id":"https://openalex.org/C518677369","wikidata":"https://www.wikidata.org/wiki/Q202833","display_name":"Social media","level":2,"score":0.44665783643722534},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.434872567653656},{"id":"https://openalex.org/C162356407","wikidata":"https://www.wikidata.org/wiki/Q180809","display_name":"Mass spectrometry","level":2,"score":0.4241888225078583},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3850957453250885},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.3525787591934204},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.3438342809677124},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.333212673664093},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.2911532521247864},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000143","descriptor_name":"Acids","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":true},{"descriptor_ui":"D002849","descriptor_name":"Chromatography, Gas","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002852","descriptor_name":"Chromatography, Ion Exchange","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003201","descriptor_name":"Computers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006880","descriptor_name":"Hydroxy Acids","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false},{"descriptor_ui":"D012997","descriptor_name":"Solvents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013058","descriptor_name":"Mass Spectrometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/ac60358a074","doi":"https://doi.org/10.1021/ac60358a074","is_oa":false,"landing_page_url":"https://doi.org/10.1021/ac60358a074","pdf_url":null,"source":{"id":"https://openalex.org/S191963794","display_name":"Analytical Chemistry","issn_l":"0003-2700","issn":["0003-2700","1520-6882"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical Chemistry","raw_type":"journal-article"},{"id":"pmid:1147254","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1147254","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Analytical chemistry","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1918747326","https://openalex.org/W1919065297","https://openalex.org/W1949114766","https://openalex.org/W1965303986","https://openalex.org/W1968177201","https://openalex.org/W1990258081","https://openalex.org/W1997528838","https://openalex.org/W2002845377","https://openalex.org/W2011946070","https://openalex.org/W2016375931","https://openalex.org/W2041750619","https://openalex.org/W2043843418","https://openalex.org/W2059098874","https://openalex.org/W2061026667","https://openalex.org/W2070995684","https://openalex.org/W2078257579","https://openalex.org/W2079498734","https://openalex.org/W2080894200","https://openalex.org/W2085096011","https://openalex.org/W2145130069","https://openalex.org/W2148071112","https://openalex.org/W2150764486","https://openalex.org/W2260164282","https://openalex.org/W2317553488","https://openalex.org/W2321700062","https://openalex.org/W4298227675"],"related_works":["https://openalex.org/W3032140916","https://openalex.org/W6888938748","https://openalex.org/W1910139235","https://openalex.org/W1988211330","https://openalex.org/W2000661865","https://openalex.org/W760405079","https://openalex.org/W1978931815","https://openalex.org/W3202667006","https://openalex.org/W2124067510","https://openalex.org/W1930641972"],"abstract_inverted_index":{"ADVERTISEMENT":[0],"RETURN":[1],"TO":[2],"ISSUEPREVArticleNEXTQuantitative":[3],"metabolic":[4],"profiling":[5],"of":[6,15,55,90,116],"urinary":[7],"organic":[8],"acids":[9],"by":[10,97],"gas":[11],"chromatography-mass":[12],"spectrometry.":[13],"Comparison":[14],"isolation":[16],"methodsJohn":[17],"A.":[18],"Thompson":[19],"and":[20,65,70,99,143,160,176,178],"Sanford":[21],"P.":[22],"MarkeyCite":[23],"this:":[24],"Anal.":[25],"Chem.":[26],"1975,":[27],"47,":[28],"8,":[29],"1313\u20131321Publication":[30],"Date":[31],"(Print):July":[32],"1,":[33],"1975Publication":[34],"History":[35],"Published":[36],"online1":[37],"May":[38],"2002Published":[39],"inissue":[40],"1":[41],"July":[42],"1975https://doi.org/10.1021/ac60358a074RIGHTS":[43],"&":[44],"PERMISSIONSArticle":[45],"Views490Altmetric-Citations128LEARN":[46],"ABOUT":[47],"THESE":[48],"METRICSArticle":[49],"Views":[50],"are":[51,74,87],"the":[52,83,88,117,128,141,144,149,156,162],"COUNTER-compliant":[53],"sum":[54],"full":[56],"text":[57],"article":[58,122],"downloads":[59],"since":[60],"November":[61],"2008":[62],"(both":[63],"PDF":[64,184],"HTML)":[66],"across":[67],"all":[68],"institutions":[69],"individuals.":[71],"These":[72],"metrics":[73],"regularly":[75],"updated":[76,100],"to":[77,82],"reflect":[78],"usage":[79],"leading":[80],"up":[81],"last":[84],"few":[85],"days.Citations":[86],"number":[89],"other":[91],"articles":[92],"citing":[93],"this":[94],"article,":[95],"calculated":[96],"Crossref":[98,106],"daily.":[101],"Find":[102,152],"more":[103,153],"information":[104,154],"about":[105,140],"citation":[107],"counts.The":[108],"Altmetric":[109,157],"Attention":[110,158],"Score":[111,159],"is":[112,164],"a":[113,120,133],"quantitative":[114],"measure":[115],"attention":[118],"that":[119],"research":[121],"has":[123],"received":[124],"online.":[125],"Clicking":[126],"on":[127,155],"donut":[129],"icon":[130],"will":[131],"load":[132],"page":[134],"at":[135],"altmetric.com":[136],"with":[137,172],"additional":[138],"details":[139],"score":[142,163],"social":[145],"media":[146],"presence":[147],"for":[148],"given":[150],"article.":[151],"how":[161],"calculated.":[165],"Share":[166,181],"Add":[167],"toView":[168],"InAdd":[169],"Full":[170],"Text":[171],"ReferenceAdd":[173],"Description":[174],"ExportRISCitationCitation":[175],"abstractCitation":[177],"referencesMore":[179],"Options":[180],"onFacebookTwitterWechatLinked":[182],"InReddit":[183],"(972":[185],"KB)":[186],"Get":[187,189],"e-Alerts":[188,190]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}