{"id":"https://openalex.org/W2033689828","doi":"https://doi.org/10.1007/s11745-010-3437-9","title":"Acyl\u2010CoA Binding Protein Gene Ablation Induces Pre\u2010implantation Embryonic Lethality in Mice","display_name":"Acyl\u2010CoA Binding Protein Gene Ablation Induces Pre\u2010implantation Embryonic Lethality in Mice","publication_year":2010,"publication_date":"2010-06-17","ids":{"openalex":"https://openalex.org/W2033689828","doi":"https://doi.org/10.1007/s11745-010-3437-9","mag":"2033689828","pmid":"https://pubmed.ncbi.nlm.nih.gov/20559753","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2997683"},"language":"en","primary_location":{"id":"doi:10.1007/s11745-010-3437-9","doi":"https://doi.org/10.1007/s11745-010-3437-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11745-010-3437-9","pdf_url":null,"source":{"id":"https://openalex.org/S115623499","display_name":"Lipids","issn_l":"0024-4201","issn":["0024-4201","1558-9307"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lipids","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2997683","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047010455","display_name":"Danilo Landrock","orcid":"https://orcid.org/0009-0005-5368-8122","observed_orcids":["https://orcid.org/0009-0005-5368-8122"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Danilo Landrock","raw_affiliation_strings":["Department of Pathobiology Texas A&M University TAMU 4467 College Station TX 77843\u20104467 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathobiology Texas A&M University TAMU 4467 College Station TX 77843\u20104467 USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091544616","display_name":"Barbara P. Atshaves","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Barbara P. Atshaves","raw_affiliation_strings":["Department of Physiology and Pharmacology Texas A&M University TAMU 4466 College Station TX 77843\u20104466 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Pharmacology Texas A&M University TAMU 4466 College Station TX 77843\u20104466 USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081214816","display_name":"Avery L. McIntosh","orcid":"https://orcid.org/0000-0002-8663-8990","observed_orcids":["https://orcid.org/0000-0002-8663-8990"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Avery L. McIntosh","raw_affiliation_strings":["Department of Physiology and Pharmacology Texas A&M University TAMU 4466 College Station TX 77843\u20104466 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Pharmacology Texas A&M University TAMU 4466 College Station TX 77843\u20104466 USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063582701","display_name":"Kerstin K. Landrock","orcid":"https://orcid.org/0000-0001-5494-198X","observed_orcids":["https://orcid.org/0000-0001-5494-198X"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kerstin K. Landrock","raw_affiliation_strings":["Department of Physiology and Pharmacology Texas A&M University TAMU 4466 College Station TX 77843\u20104466 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Pharmacology Texas A&M University TAMU 4466 College Station TX 77843\u20104466 USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046497078","display_name":"Friedhelm Schroeder","orcid":"https://orcid.org/0000-0002-3545-7962","observed_orcids":["https://orcid.org/0000-0002-3545-7962"]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Friedhelm Schroeder","raw_affiliation_strings":["Department of Physiology and Pharmacology Texas A&M University TAMU 4466 College Station TX 77843\u20104466 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physiology and Pharmacology Texas A&M University TAMU 4466 College Station TX 77843\u20104466 USA","institution_ids":["https://openalex.org/I91045830"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5056901612","display_name":"Ann B. Kier","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I91045830","display_name":"Texas A&M University","ror":"https://ror.org/01f5ytq51","country_code":"US","type":"education","lineage":["https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ann B. Kier","raw_affiliation_strings":["Department of Pathobiology Texas A&M University TAMU 4467 College Station TX 77843\u20104467 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathobiology Texas A&M University TAMU 4467 College Station TX 77843\u20104467 USA","institution_ids":["https://openalex.org/I91045830"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5056901612"],"corresponding_institution_ids":["https://openalex.org/I91045830"],"apc_list":{"value":3589,"currency":"USD","value_usd":3589},"apc_paid":null,"fwci":1.6951,"has_fulltext":false,"cited_by_count":43,"citation_normalized_percentile":{"value":0.80288669,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"45","issue":"7","first_page":"567","last_page":"580"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.5449000000953674,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11844","display_name":"Lipid metabolism and biosynthesis","score":0.5449000000953674,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11618","display_name":"Cholesterol and Lipid Metabolism","score":0.13040000200271606,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.08290000259876251,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acyl-coa-binding-protein","display_name":"acyl-CoA binding protein","score":0.9990000128746033},{"id":"https://openalex.org/keywords/intracellular-lipid-binding-proteins","display_name":"intracellular lipid binding proteins","score":0.925000011920929},{"id":"https://openalex.org/keywords/sterol-carrier-protein-2","display_name":"sterol carrier protein 2","score":0.9440000057220459},{"id":"https://openalex.org/keywords/compensatory-upregulation","display_name":"compensatory upregulation","score":0.7239999771118164},{"id":"https://openalex.org/keywords/mouse-embryonic-development","display_name":"mouse embryo development","score":0.6359999775886536},{"id":"https://openalex.org/keywords/blastocyst","display_name":"blastocyst","score":0.5270000100135803},{"id":"https://openalex.org/keywords/zygote","display_name":"zygote","score":0.6570000052452087}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6880298852920532},{"id":"https://openalex.org/C196843134","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryo","level":2,"score":0.6426519155502319},{"id":"https://openalex.org/C145103041","wikidata":"https://www.wikidata.org/wiki/Q1151519","display_name":"Embryonic stem cell","level":3,"score":0.4903545379638672},{"id":"https://openalex.org/C87073359","wikidata":"https://www.wikidata.org/wiki/Q33196","display_name":"Embryogenesis","level":3,"score":0.47214701771736145},{"id":"https://openalex.org/C553089730","wikidata":"https://www.wikidata.org/wiki/Q4914021","display_name":"Binding protein","level":3,"score":0.46627500653266907},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4443184733390808},{"id":"https://openalex.org/C28748434","wikidata":"https://www.wikidata.org/wiki/Q170145","display_name":"Zygote","level":4,"score":0.4417647421360016},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.43214601278305054},{"id":"https://openalex.org/C57708383","wikidata":"https://www.wikidata.org/wiki/Q260182","display_name":"Null allele","level":4,"score":0.42125141620635986},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.420210599899292},{"id":"https://openalex.org/C2778177303","wikidata":"https://www.wikidata.org/wiki/Q227717","display_name":"Blastocyst","level":4,"score":0.4174913465976715},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.37248069047927856},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2902877926826477},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.2066999077796936}],"mesh":[{"descriptor_ui":"D000214","descriptor_name":"Acyl Coenzyme A","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004622","descriptor_name":"Embryo, Mammalian","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005804","descriptor_name":"Genes, Lethal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017353","descriptor_name":"Gene Deletion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D026261","descriptor_name":"Diazepam Binding Inhibitor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D047108","descriptor_name":"Embryonic Development","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1007/s11745-010-3437-9","doi":"https://doi.org/10.1007/s11745-010-3437-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11745-010-3437-9","pdf_url":null,"source":{"id":"https://openalex.org/S115623499","display_name":"Lipids","issn_l":"0024-4201","issn":["0024-4201","1558-9307"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-70","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lipids","raw_type":"journal-article"},{"id":"pmid:20559753","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20559753","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lipids","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:2121877","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2997683","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2997683","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2997683","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Lipids","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2121877","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2997683","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8560000061988831,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G118921348","display_name":null,"funder_award_id":"DK-70965","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G2243841923","display_name":"Lipid droplet domains foster lipid storage","funder_award_id":"R56DK070965","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G3234955387","display_name":"FATTY ACID BINDING PROTEINS-LIGAND SPECIFICITY","funder_award_id":"R01DK041402","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G5786862920","display_name":"Asymmetric Distribution of Cholesterol in Membranes","funder_award_id":"R01GM031651","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G6445867506","display_name":"Lipid droplet domains foster lipid storage","funder_award_id":"R01DK070965","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6798858459","display_name":"Comparative Biomedical Research Training for Veterinarians","funder_award_id":"T32RR031229","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G9000012348","display_name":null,"funder_award_id":"DK70965","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320332505","display_name":"U.S. Public Health Service","ror":"https://ror.org/05xf94514"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":87,"referenced_works":["https://openalex.org/W36236453","https://openalex.org/W1495601548","https://openalex.org/W1579596229","https://openalex.org/W1579669248","https://openalex.org/W1586410777","https://openalex.org/W1763805809","https://openalex.org/W1846979937","https://openalex.org/W1882876741","https://openalex.org/W1965309337","https://openalex.org/W1966182526","https://openalex.org/W1966478849","https://openalex.org/W1967643709","https://openalex.org/W1968182352","https://openalex.org/W1968703258","https://openalex.org/W1969026949","https://openalex.org/W1969975247","https://openalex.org/W1972744939","https://openalex.org/W1975599463","https://openalex.org/W1975742878","https://openalex.org/W1975880030","https://openalex.org/W1976184612","https://openalex.org/W1978976566","https://openalex.org/W1980057782","https://openalex.org/W1980541658","https://openalex.org/W1984446269","https://openalex.org/W1988206655","https://openalex.org/W2000829730","https://openalex.org/W2007966392","https://openalex.org/W2008227124","https://openalex.org/W2015140270","https://openalex.org/W2021398185","https://openalex.org/W2023230553","https://openalex.org/W2024251288","https://openalex.org/W2025043783","https://openalex.org/W2028340122","https://openalex.org/W2028532022","https://openalex.org/W2035602584","https://openalex.org/W2038328541","https://openalex.org/W2042881415","https://openalex.org/W2044020716","https://openalex.org/W2047233540","https://openalex.org/W2047667571","https://openalex.org/W2049315339","https://openalex.org/W2050031321","https://openalex.org/W2050445974","https://openalex.org/W2055298300","https://openalex.org/W2056274102","https://openalex.org/W2057477742","https://openalex.org/W2062533493","https://openalex.org/W2069774708","https://openalex.org/W2070237777","https://openalex.org/W2070498975","https://openalex.org/W2072494058","https://openalex.org/W2072922104","https://openalex.org/W2073387842","https://openalex.org/W2082442877","https://openalex.org/W2082589024","https://openalex.org/W2090349117","https://openalex.org/W2090415246","https://openalex.org/W2092918496","https://openalex.org/W2093537983","https://openalex.org/W2102106861","https://openalex.org/W2102940990","https://openalex.org/W2105072053","https://openalex.org/W2106531102","https://openalex.org/W2107277218","https://openalex.org/W2114360920","https://openalex.org/W2119365541","https://openalex.org/W2121546157","https://openalex.org/W2122829099","https://openalex.org/W2129226972","https://openalex.org/W2129338435","https://openalex.org/W2139593118","https://openalex.org/W2145158439","https://openalex.org/W2147073885","https://openalex.org/W2158100456","https://openalex.org/W2167411606","https://openalex.org/W2190083694","https://openalex.org/W2242477415","https://openalex.org/W2259678263","https://openalex.org/W2271727959","https://openalex.org/W2411074224","https://openalex.org/W2411684176","https://openalex.org/W2412204724","https://openalex.org/W4242150355","https://openalex.org/W4254482705","https://openalex.org/W4301052166"],"related_works":["https://openalex.org/W6979742268","https://openalex.org/W2144011005","https://openalex.org/W1966182526","https://openalex.org/W2759064862","https://openalex.org/W2054800964","https://openalex.org/W1970641718","https://openalex.org/W2613781870","https://openalex.org/W2311334086","https://openalex.org/W2093766606","https://openalex.org/W2095873113"],"abstract_inverted_index":{"Unique":[0],"among":[1],"the":[2,27,45,106,140,174,183],"intracellular":[3,186],"lipid":[4,187],"binding":[5,8,119,169,188],"proteins,":[6,120,170],"acyl-CoA":[7],"protein":[9,24,148,189],"(ACBP)":[10],"exclusively":[11],"binds":[12],"long-chain":[13],"fatty":[14],"acyl-CoAs":[15],"(LCFA-CoAs).":[16],"To":[17],"test":[18],"if":[19],"ACBP":[20,28,38,144,181],"is":[21,145,182],"an":[22,76,146],"essential":[23,147],"in":[25,35,193,200],"mammals,":[26],"gene":[29],"was":[30],"ablated":[31],"by":[32,162],"homologous":[33],"recombination":[34],"mice.":[36],"While":[37,91],"heterozygotes":[39,46],"appeared":[40],"phenotypically":[41],"normal,":[42],"intercrossing":[43],"of":[44,84,156,165],"did":[47],"not":[48,95],"produce":[49],"any":[50,98],"live":[51],"homozygous":[52,70],"deficient":[53],"(null)":[54],"ACBP((-/-))":[55],"pups.":[56],"Heterozygous":[57],"and":[58,111,125,153],"wild":[59],"type":[60],"embryos":[61,72,88,93,102],"were":[62,73,94,103,130],"detected":[63,96,104],"at":[64,80,97,105,133,173],"all":[65],"post-implantation":[66],"stages,":[67],"but":[68,171],"no":[69],"ACBP-null":[71,92,101],"obtained-suggesting":[74],"that":[75,87,143,180],"embryonic":[77,151,194],"lethality":[78,195],"occurred":[79],"a":[81],"pre-implantation":[82,114,176],"stage":[83],"development,":[85],"or":[86],"never":[89],"formed.":[90],"blastocyst":[99],"stage,":[100],"morula":[107],"(8-cell),":[108],"cleavage":[109],"(2-cell),":[110],"zygote":[112],"(1-cell)":[113],"stages.":[115,135,177],"Two":[116],"other":[117,167],"LCFA-CoA":[118,168],"sterol":[121,126],"carrier":[122,127],"protein-2":[123],"(SCP-2)":[124],"protein-x":[128],"(SCP-x)":[129],"significantly":[131],"upregulated":[132],"these":[134],"These":[136],"findings":[137],"demonstrate":[138],"for":[139,150],"first":[141,184],"time":[142],"required":[149],"development":[152],"its":[154,197],"loss":[155],"function":[157],"may":[158],"be":[159],"initially":[160],"compensated":[161],"concomitant":[163],"upregulation":[164],"two":[166],"only":[172],"earliest":[175],"The":[178],"fact":[179],"known":[185],"whose":[190],"deletion":[191],"results":[192],"suggests":[196],"vital":[198],"importance":[199],"mammals.":[201]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":7},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}