{"id":"https://openalex.org/W2033250487","doi":"https://doi.org/10.1016/0006-8993(83)90269-x","title":"Blockade of synaptic transmission in the squid giant synapse by a spider toxin (JSTX)","display_name":"Blockade of synaptic transmission in the squid giant synapse by a spider toxin (JSTX)","publication_year":1983,"publication_date":"1983-11-01","ids":{"openalex":"https://openalex.org/W2033250487","doi":"https://doi.org/10.1016/0006-8993(83)90269-x","mag":"2033250487","pmid":"https://pubmed.ncbi.nlm.nih.gov/6315161"},"language":"en","primary_location":{"id":"doi:10.1016/0006-8993(83)90269-x","doi":"https://doi.org/10.1016/0006-8993(83)90269-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0006-8993(83)90269-x","pdf_url":null,"source":{"id":"https://openalex.org/S96638545","display_name":"Brain Research","issn_l":"0006-8993","issn":["0006-8993","1872-6240"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109979716","display_name":"Nobufumi Kawai","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nobufumi Kawai","raw_affiliation_strings":["Department of Neurobiology, Tokyo Metropolitan Institute for Neurosciences, 2-6, Musashidai, Fuchu-City, Tokyo 183 (Japan)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurobiology, Tokyo Metropolitan Institute for Neurosciences, 2-6, Musashidai, Fuchu-City, Tokyo 183 (Japan)","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038169559","display_name":"Shunichi Yamagishi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210145863","display_name":"National Institute for Physiological Sciences","ror":"https://ror.org/048v13307","country_code":"JP","type":"facility","lineage":["https://openalex.org/I1319490839","https://openalex.org/I199525922","https://openalex.org/I4210145863"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shunichi Yamagishi","raw_affiliation_strings":["Department of Biological Membrane, National Institute for Physiological Sciences, Myodaiji, Okazaki-City, Aichi 444 (Japan)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Membrane, National Institute for Physiological Sciences, Myodaiji, Okazaki-City, Aichi 444 (Japan)","institution_ids":["https://openalex.org/I4210145863"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108268419","display_name":"Mitsuyoshi L. Saito","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mitsuyoshi Saito","raw_affiliation_strings":["Department of Neurobiology, Tokyo Metropolitan Institute for Neurosciences, 2-6, Musashidai, Fuchu-City, Tokyo 183 (Japan)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurobiology, Tokyo Metropolitan Institute for Neurosciences, 2-6, Musashidai, Fuchu-City, Tokyo 183 (Japan)","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014952697","display_name":"Kishio Furuya","orcid":"https://orcid.org/0000-0003-4714-8689","observed_orcids":["https://orcid.org/0000-0003-4714-8689"]},"institutions":[{"id":"https://openalex.org/I4210145863","display_name":"National Institute for Physiological Sciences","ror":"https://ror.org/048v13307","country_code":"JP","type":"facility","lineage":["https://openalex.org/I1319490839","https://openalex.org/I199525922","https://openalex.org/I4210145863"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Kishio Furuya","raw_affiliation_strings":["Department of Biological Membrane, National Institute for Physiological Sciences, Myodaiji, Okazaki-City, Aichi 444 (Japan)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biological Membrane, National Institute for Physiological Sciences, Myodaiji, Okazaki-City, Aichi 444 (Japan)","institution_ids":["https://openalex.org/I4210145863"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":0.9345,"has_fulltext":false,"cited_by_count":59,"citation_normalized_percentile":{"value":0.68152939,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"278","issue":"1-2","first_page":"346","last_page":"349"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11818","display_name":"Nicotinic Acetylcholine Receptors Study","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/spider-toxins","display_name":"spider toxins","score":0.9789999723434448},{"id":"https://openalex.org/keywords/synaptic-transmission","display_name":"synaptic transmission","score":0.6600000262260437},{"id":"https://openalex.org/keywords/squid-giant-synapse","display_name":"squid giant synapse","score":0.9399999976158142},{"id":"https://openalex.org/keywords/stellate-ganglion","display_name":"stellate ganglion","score":0.9900000095367432},{"id":"https://openalex.org/keywords/excitatory-postsynaptic-potentials","display_name":"excitatory postsynaptic potentials","score":0.9900000095367432},{"id":"https://openalex.org/keywords/glutamate","display_name":"glutamate","score":0.7749999761581421},{"id":"https://openalex.org/keywords/receptor-desensitization","display_name":"receptor desensitization","score":0.843999981880188},{"id":"https://openalex.org/keywords/glutamate-as-neurotransmitter","display_name":"glutamate as neurotransmitter","score":0.6930000185966492},{"id":"https://openalex.org/keywords/presynaptic-action-potential","display_name":"presynaptic action potential","score":0.7200000286102295}],"concepts":[{"id":"https://openalex.org/C112592302","wikidata":"https://www.wikidata.org/wiki/Q1207387","display_name":"Excitatory postsynaptic potential","level":3,"score":0.7722041606903076},{"id":"https://openalex.org/C15358309","wikidata":"https://www.wikidata.org/wiki/Q24780345","display_name":"Spider toxin","level":4,"score":0.7044288516044617},{"id":"https://openalex.org/C200170125","wikidata":"https://www.wikidata.org/wiki/Q969316","display_name":"Neurotransmission","level":3,"score":0.6578550934791565},{"id":"https://openalex.org/C197341189","wikidata":"https://www.wikidata.org/wiki/Q863533","display_name":"Postsynaptic potential","level":3,"score":0.6023480892181396},{"id":"https://openalex.org/C99223954","wikidata":"https://www.wikidata.org/wiki/Q5419646","display_name":"Excitatory synapse","level":4,"score":0.5593461990356445},{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.5538208484649658},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5353992581367493},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5044890642166138},{"id":"https://openalex.org/C127445978","wikidata":"https://www.wikidata.org/wiki/Q187181","display_name":"Synapse","level":2,"score":0.4493091106414795},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3613300025463104},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35106489062309265},{"id":"https://openalex.org/C17077164","wikidata":"https://www.wikidata.org/wiki/Q1185869","display_name":"Inhibitory postsynaptic potential","level":2,"score":0.3337813913822174},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.13040262460708618},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1065925657749176}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001180","descriptor_name":"Arthropod Venoms","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004594","descriptor_name":"Electrophysiology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005728","descriptor_name":"Ganglia, Sympathetic","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D005971","descriptor_name":"Glutamates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007608","descriptor_name":"Kainic Acid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D009435","descriptor_name":"Synaptic Transmission","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D013111","descriptor_name":"Spider Venoms","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D049832","descriptor_name":"Decapodiformes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0006-8993(83)90269-x","doi":"https://doi.org/10.1016/0006-8993(83)90269-x","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0006-8993(83)90269-x","pdf_url":null,"source":{"id":"https://openalex.org/S96638545","display_name":"Brain Research","issn_l":"0006-8993","issn":["0006-8993","1872-6240"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research","raw_type":"journal-article"},{"id":"pmid:6315161","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6315161","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320912","display_name":"Ministry of Education, Culture, Sports, Science and Technology","ror":"https://ror.org/048rj2z13"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1981455893","https://openalex.org/W1981755695","https://openalex.org/W1987460091","https://openalex.org/W2000121955","https://openalex.org/W2011459292","https://openalex.org/W2020137064","https://openalex.org/W2020949479","https://openalex.org/W2051211731","https://openalex.org/W2066042184","https://openalex.org/W2073552497","https://openalex.org/W2083622839","https://openalex.org/W2141472106","https://openalex.org/W2146601122","https://openalex.org/W2147635124","https://openalex.org/W2152748319"],"related_works":["https://openalex.org/W2007131117","https://openalex.org/W25699408","https://openalex.org/W2767552274","https://openalex.org/W2503181794","https://openalex.org/W2047730283","https://openalex.org/W2020137064","https://openalex.org/W1992932174","https://openalex.org/W1976281938","https://openalex.org/W2070998343","https://openalex.org/W1994634361"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2014,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}