{"id":"https://openalex.org/W2032983992","doi":"https://doi.org/10.4248/ijos11070","title":"Distribution and relative activity of matrix metalloproteinase\u20102 in human coronal dentin","display_name":"Distribution and relative activity of matrix metalloproteinase\u20102 in human coronal dentin","publication_year":2011,"publication_date":"2011-10-01","ids":{"openalex":"https://openalex.org/W2032983992","doi":"https://doi.org/10.4248/ijos11070","mag":"2032983992","pmid":"https://pubmed.ncbi.nlm.nih.gov/22010577","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3469976"},"language":"en","primary_location":{"id":"doi:10.4248/ijos11070","doi":"https://doi.org/10.4248/ijos11070","is_oa":true,"landing_page_url":"https://doi.org/10.4248/ijos11070","pdf_url":"https://www.nature.com/articles/ijos201126.pdf","source":{"id":"https://openalex.org/S44743489","display_name":"International Journal of Oral Science","issn_l":"1674-2818","issn":["1674-2818","2049-3169"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Oral Science","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/ijos201126.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109918088","display_name":"Lee W. Boushell","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Lee W Boushell","raw_affiliation_strings":["Department of Operative Dentistry, School of Dentistry, University of North Carolina, Chapel Hill, NC 27599, USA. Boushell@dentistry.unc.edu","Department of Operative Dentistry, School of Dentistry, University of North Carolina, Chapel Hill, NC 27599, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Operative Dentistry, School of Dentistry, University of North Carolina, Chapel Hill, NC 27599, USA. Boushell@dentistry.unc.edu","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Department of Operative Dentistry, School of Dentistry, University of North Carolina, Chapel Hill, NC 27599, USA","institution_ids":["https://openalex.org/I114027177"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073378373","display_name":"Masaru Kaku","orcid":"https://orcid.org/0000-0002-7988-6435","observed_orcids":["https://orcid.org/0000-0002-7988-6435"]},"institutions":[{"id":"https://openalex.org/I71395657","display_name":"Niigata University","ror":"https://ror.org/04ww21r56","country_code":"JP","type":"education","lineage":["https://openalex.org/I71395657"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaru Kaku","raw_affiliation_strings":["Department of Bio\u2010Prosthodontics, Medical and Dental Science, Niigata University Graduate School Chuo\u2010ku, Niigata City, 951-8514, Japan","Department of Bio\u2010Prosthodontics, Medical and Dental Science, Niigata University Graduate School Chuo\u2010ku, Niigata City, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Bio\u2010Prosthodontics, Medical and Dental Science, Niigata University Graduate School Chuo\u2010ku, Niigata City, 951-8514, Japan","institution_ids":["https://openalex.org/I71395657"]},{"raw_affiliation_string":"Department of Bio\u2010Prosthodontics, Medical and Dental Science, Niigata University Graduate School Chuo\u2010ku, Niigata City, Japan","institution_ids":["https://openalex.org/I71395657"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083278183","display_name":"Yoshiyuki Mochida","orcid":"https://orcid.org/0000-0002-2115-4303","observed_orcids":["https://orcid.org/0000-0002-2115-4303"]},"institutions":[{"id":"https://openalex.org/I111088046","display_name":"Boston University","ror":"https://ror.org/05qwgg493","country_code":"US","type":"education","lineage":["https://openalex.org/I111088046"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yoshiyuki Mochida","raw_affiliation_strings":["Department of Periodontology and Oral Biology, Division of Oral Biology, Boston University, Henry M. Goldman School of Dental Medicine, Center for Advanced Biomedical Research, Boston, 02118, MA, USA","Department of Periodontology and Oral Biology, Division of Oral Biology, Boston University, Henry M. Goldman School of Dental Medicine, Center for Advanced Biomedical Research, Boston, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Periodontology and Oral Biology, Division of Oral Biology, Boston University, Henry M. Goldman School of Dental Medicine, Center for Advanced Biomedical Research, Boston, 02118, MA, USA","institution_ids":["https://openalex.org/I111088046"]},{"raw_affiliation_string":"Department of Periodontology and Oral Biology, Division of Oral Biology, Boston University, Henry M. Goldman School of Dental Medicine, Center for Advanced Biomedical Research, Boston, USA","institution_ids":["https://openalex.org/I111088046"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111520627","display_name":"Mitsuo Yamauchi","orcid":"https://orcid.org/0000-0003-4212-3992","observed_orcids":["https://orcid.org/0000-0003-4212-3992"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mitsuo Yamauchi","raw_affiliation_strings":["Dental Research Center, School of Dentistry, University of North Carolina, Chapel Hill, 27599, NC, USA","Dental Research Center, School of Dentistry University of North Carolina, Chapel Hill, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dental Research Center, School of Dentistry, University of North Carolina, Chapel Hill, 27599, NC, USA","institution_ids":["https://openalex.org/I114027177"]},{"raw_affiliation_string":"Dental Research Center, School of Dentistry University of North Carolina, Chapel Hill, USA","institution_ids":["https://openalex.org/I114027177"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5109918088"],"corresponding_institution_ids":["https://openalex.org/I114027177"],"apc_list":{"value":3890,"currency":"USD","value_usd":3890},"apc_paid":{"value":3890,"currency":"USD","value_usd":3890},"fwci":0.9315,"has_fulltext":true,"cited_by_count":22,"citation_normalized_percentile":{"value":0.75330511,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"3","issue":"4","first_page":"192","last_page":"199"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12110","display_name":"Bone and Dental Protein Studies","score":0.3515999913215637,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12110","display_name":"Bone and Dental Protein Studies","score":0.3515999913215637,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.32199999690055847,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10113","display_name":"Dental materials and restorations","score":0.21960000693798065,"subfield":{"id":"https://openalex.org/subfields/3505","display_name":"Orthodontics"},"field":{"id":"https://openalex.org/fields/35","display_name":"Dentistry"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mmp-2","display_name":"MMP-2","score":1.0},{"id":"https://openalex.org/keywords/coronal-dentin","display_name":"coronal dentin","score":0.8320000171661377},{"id":"https://openalex.org/keywords/dentin-matrix","display_name":"dentin matrix","score":0.5680000185966492},{"id":"https://openalex.org/keywords/dentino-enamel-junction","display_name":"dentino-enamel junction","score":0.7599999904632568},{"id":"https://openalex.org/keywords/demineralized-dentin","display_name":"demineralized dentin","score":0.859000027179718},{"id":"https://openalex.org/keywords/gelatinase-activity","display_name":"gelatinase activity","score":0.8880000114440918},{"id":"https://openalex.org/keywords/prommp-2","display_name":"proMMP-2","score":0.777999997138977},{"id":"https://openalex.org/keywords/human-molars","display_name":"human molars","score":0.6399999856948853}],"concepts":[{"id":"https://openalex.org/C2779263046","wikidata":"https://www.wikidata.org/wiki/Q189637","display_name":"Dentin","level":2,"score":0.9152477383613586},{"id":"https://openalex.org/C85265743","wikidata":"https://www.wikidata.org/wiki/Q885458","display_name":"Blot","level":3,"score":0.7072206735610962},{"id":"https://openalex.org/C2776415932","wikidata":"https://www.wikidata.org/wiki/Q48743","display_name":"Western blot","level":3,"score":0.7044886350631714},{"id":"https://openalex.org/C109523444","wikidata":"https://www.wikidata.org/wiki/Q424216","display_name":"Matrix metalloproteinase","level":2,"score":0.6665616631507874},{"id":"https://openalex.org/C177430391","wikidata":"https://www.wikidata.org/wiki/Q1173648","display_name":"Zymography","level":3,"score":0.6474347710609436},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6275469064712524},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.5416396856307983},{"id":"https://openalex.org/C202271784","wikidata":"https://www.wikidata.org/wiki/Q189218","display_name":"Molar","level":2,"score":0.46569833159446716},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.34610024094581604},{"id":"https://openalex.org/C199343813","wikidata":"https://www.wikidata.org/wiki/Q12128","display_name":"Dentistry","level":1,"score":0.23617064952850342},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.22381284832954407},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.09130609035491943},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D003804","descriptor_name":"Dentin","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D004591","descriptor_name":"Electrophoresis, Polyacrylamide Gel","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004792","descriptor_name":"Enzyme Precursors","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008964","descriptor_name":"Molar, Third","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D014018","descriptor_name":"Tissue Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015153","descriptor_name":"Blotting, Western","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017001","descriptor_name":"Tooth Demineralization","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D019228","descriptor_name":"Tooth Crown","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D020778","descriptor_name":"Matrix Metalloproteinase 2","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D020778","descriptor_name":"Matrix Metalloproteinase 2","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.4248/ijos11070","doi":"https://doi.org/10.4248/ijos11070","is_oa":true,"landing_page_url":"https://doi.org/10.4248/ijos11070","pdf_url":"https://www.nature.com/articles/ijos201126.pdf","source":{"id":"https://openalex.org/S44743489","display_name":"International Journal of Oral Science","issn_l":"1674-2818","issn":["1674-2818","2049-3169"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Oral Science","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3469976","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3469976","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Int J Oral Sci","raw_type":"Text"},{"id":"pmid:22010577","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22010577","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of oral science","raw_type":"Journal Article"},{"id":"pmh:cdr.lib.unc.edu:s1784t04f","doi":null,"is_oa":false,"landing_page_url":"https://doi.org/10.17615/qzh9-mt50","pdf_url":null,"source":{"id":"https://openalex.org/S4306401075","display_name":"Carolina Digital Repository (University of North Carolina at Chapel Hill)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I114027177","host_organization_name":"University of North Carolina at Chapel Hill","host_organization_lineage":["https://openalex.org/I114027177"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"International Journal of Oral Science, 3(4)","raw_type":"Article"},{"id":"doi:10.17615/qzh9-mt50","doi":"https://doi.org/10.17615/qzh9-mt50","is_oa":true,"landing_page_url":"https://doi.org/10.17615/qzh9-mt50","pdf_url":null,"source":{"id":"https://openalex.org/S7407051488","display_name":"UNC Libraries","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article-journal"}],"best_oa_location":{"id":"doi:10.4248/ijos11070","doi":"https://doi.org/10.4248/ijos11070","is_oa":true,"landing_page_url":"https://doi.org/10.4248/ijos11070","pdf_url":"https://www.nature.com/articles/ijos201126.pdf","source":{"id":"https://openalex.org/S44743489","display_name":"International Journal of Oral Science","issn_l":"1674-2818","issn":["1674-2818","2049-3169"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-3","ki-jl-2","medline","norway-2","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Oral Science","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2081413662","display_name":"EVC2: A novel modulator in tooth development","funder_award_id":"R01DE019527","funder_id":"https://openalex.org/F4320337365","funder_display_name":"National Institute of Dental and Craniofacial Research"},{"id":"https://openalex.org/G6208251368","display_name":"Study on senescence-associated tumor promotion","funder_award_id":"23300352","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G8797404201","display_name":"Role of Vwc2-assisted activin signaling in bone formation","funder_award_id":"R21AR057451","funder_id":"https://openalex.org/F4320337362","funder_display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"},{"id":"https://openalex.org/F4320337362","display_name":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","ror":"https://ror.org/006zn3t30"},{"id":"https://openalex.org/F4320337365","display_name":"National Institute of Dental and Craniofacial Research","ror":"https://ror.org/004a2wv92"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2032983992.pdf","grobid_xml":"https://content.openalex.org/works/W2032983992.grobid-xml"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W1494267392","https://openalex.org/W1542924344","https://openalex.org/W1964682327","https://openalex.org/W1985092801","https://openalex.org/W1993281392","https://openalex.org/W1994941676","https://openalex.org/W2004191794","https://openalex.org/W2010941865","https://openalex.org/W2017675216","https://openalex.org/W2023153539","https://openalex.org/W2041022033","https://openalex.org/W2052166242","https://openalex.org/W2056762184","https://openalex.org/W2058131840","https://openalex.org/W2062015617","https://openalex.org/W2079385179","https://openalex.org/W2088739694","https://openalex.org/W2097158736","https://openalex.org/W2100876774","https://openalex.org/W2118914677","https://openalex.org/W2121640215","https://openalex.org/W2122813984","https://openalex.org/W2135215532","https://openalex.org/W2146721894","https://openalex.org/W2154730999","https://openalex.org/W2157583568","https://openalex.org/W2160618865","https://openalex.org/W2162585191","https://openalex.org/W2163693751","https://openalex.org/W2168920694","https://openalex.org/W2170055853"],"related_works":["https://openalex.org/W2249110061","https://openalex.org/W2088739694","https://openalex.org/W2460374416","https://openalex.org/W2403969815","https://openalex.org/W2136067863","https://openalex.org/W4405165115","https://openalex.org/W2028094728","https://openalex.org/W2157583568","https://openalex.org/W2347527445","https://openalex.org/W2782614367"],"abstract_inverted_index":{"The":[0,26,98,128,197],"presence":[1],"of":[2,28,44,101,130,182,184,199,210,223,227,242],"matrix":[3],"metalloproteinase-2":[4],"(MMP-2)":[5],"in":[6,17,40,107,156,166,176,201,207,219],"dentin":[7,21,58,105,109,204,211],"has":[8],"been":[9],"reported,":[10],"but":[11],"its":[12],"distribution":[13,36],"and":[14,37,56,61,77,95,123,144,152,159,161,188,217,231],"activity":[15,39,170,190,233],"level":[16],"mature":[18,153],"human":[19,47,202],"coronal":[20,203],"are":[22],"not":[23,235],"well":[24],"understood.":[25],"purpose":[27],"this":[29],"study":[30],"was":[31,64,80,89,133,174,191,205],"to":[32,150],"determine":[33],"the":[34,108,157,167,180,208,214,220,238],"MMP-2":[35,63,78,102,131,173,200],"relative":[38],"demineralized":[41],"dentin.":[42,224],"Crowns":[43],"twenty":[45],"eight":[46],"molars":[48],"were":[49,111],"sectioned":[50],"into":[51],"inner":[52],"(ID),":[53,119],"middle":[54,221],"(MD),":[55,122],"outer":[57],"(OD)":[59],"regions":[60,110],"demineralized.":[62],"extracted":[65],"with":[66,82,172,237],"0.33":[67],"mol":[68,72],"x":[69],"L(-1)":[70],"EDTA/2":[71],"xL(-1)":[73],"guanidine-HCl,":[74],"pH":[75],"7.4,":[76],"concentration":[79,132,198],"estimated":[81,239],"enzyme-linked":[83],"immunoabsorbant":[84],"assay":[85],"(ELISA).":[86],"Further":[87],"characterization":[88],"accomplished":[90],"by":[91],"Western":[92,139,185,228],"blotting":[93,140],"analysis":[94,141],"gelatin":[96],"zymography.":[97],"mean":[99],"concentrations":[100,241],"per":[103],"mg":[104],"protein":[106,165,248],"significantly":[112],"different":[113],"(P":[114],"=":[115],"0.043):":[116],"0.9":[117],"ng":[118,121,125],"0.4":[120],"2.2":[124],"(OD),":[126],"respectively.":[127],"pattern":[129,181],"OD":[134],">":[135,137,193,195],"ID":[136,158,194],"MD.":[138],"detected":[142,175],"-.66":[143],"-72":[145],"kDa":[146,164],"immunopositive":[147],"proteins":[148],"corresponding":[149],"pro-":[151],"MMP-2,":[154,243],"respectively,":[155],"MD,":[160],"a":[162],"-66":[163],"OD.":[168,196],"Gelatinolytic":[169],"consistent":[171],"all":[177],"regions.":[178],"Interestingly,":[179],"levels":[183,226],"blot":[186,229],"immunodetection":[187,230],"gelatinolytic":[189,232],"MD":[192],"highest":[206],"region":[209,222,246],"that":[212],"contains":[213],"dentinoenamel":[215],"junction":[216],"least":[218],"However,":[225],"did":[234],"correlate":[236],"regional":[240],"potentially":[244],"indicating":[245],"specific":[247],"interactions.":[249]},"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}