{"id":"https://openalex.org/W2032946986","doi":"https://doi.org/10.1086/647730","title":"Clinical Effectiveness of Low-Temperature Sterilization Technologies","display_name":"Clinical Effectiveness of Low-Temperature Sterilization Technologies","publication_year":1998,"publication_date":"1998-10-01","ids":{"openalex":"https://openalex.org/W2032946986","doi":"https://doi.org/10.1086/647730","mag":"2032946986","pmid":"https://pubmed.ncbi.nlm.nih.gov/9801294"},"language":"en","primary_location":{"id":"doi:10.1086/647730","doi":"https://doi.org/10.1086/647730","is_oa":false,"landing_page_url":"https://doi.org/10.1086/647730","pdf_url":null,"source":{"id":"https://openalex.org/S129764719","display_name":"Infection Control and Hospital Epidemiology","issn_l":"0899-823X","issn":["0899-823X","1559-6834"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection Control & Hospital Epidemiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109232786","display_name":"William A. Rutala","orcid":"https://orcid.org/0009-0008-4635-8709","observed_orcids":["https://orcid.org/0009-0008-4635-8709"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I1333535994","display_name":"University of North Carolina Health Care","ror":"https://ror.org/00qz24g20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1333535994"]},{"id":"https://openalex.org/I4210123841","display_name":"University of North Carolina Hospitals","ror":"https://ror.org/0355zfr67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1333535994","https://openalex.org/I4210123841"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William A. Rutala","raw_affiliation_strings":["UNC Hospitals","University of North Carolina School of Medicine, the Department of Hospital Epidemiology, UNC Hospitals, Chapel Hill 27599-7030, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UNC Hospitals","institution_ids":["https://openalex.org/I114027177","https://openalex.org/I1333535994","https://openalex.org/I4210123841"]},{"raw_affiliation_string":"University of North Carolina School of Medicine, the Department of Hospital Epidemiology, UNC Hospitals, Chapel Hill 27599-7030, USA","institution_ids":["https://openalex.org/I114027177","https://openalex.org/I1333535994","https://openalex.org/I4210123841"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5033818354","display_name":"David J. Weber","orcid":"https://orcid.org/0000-0002-8824-1110","observed_orcids":["https://orcid.org/0000-0002-8824-1110"]},"institutions":[{"id":"https://openalex.org/I114027177","display_name":"University of North Carolina at Chapel Hill","ror":"https://ror.org/0130frc33","country_code":"US","type":"education","lineage":["https://openalex.org/I114027177"]},{"id":"https://openalex.org/I1333535994","display_name":"University of North Carolina Health Care","ror":"https://ror.org/00qz24g20","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1333535994"]},{"id":"https://openalex.org/I4210123841","display_name":"University of North Carolina Hospitals","ror":"https://ror.org/0355zfr67","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1333535994","https://openalex.org/I4210123841"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David J. Weber","raw_affiliation_strings":["UNC Hospitals","Infectious Diseases"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"UNC Hospitals","institution_ids":["https://openalex.org/I114027177","https://openalex.org/I1333535994","https://openalex.org/I4210123841"]},{"raw_affiliation_string":"Infectious Diseases","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":1.2656,"has_fulltext":false,"cited_by_count":62,"citation_normalized_percentile":{"value":0.77112179,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"19","issue":"10","first_page":"798","last_page":"804"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12744","display_name":"Medical Device Sterilization and Disinfection","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12744","display_name":"Medical Device Sterilization and Disinfection","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11000","display_name":"Infection Control in Healthcare","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11455","display_name":"Microbial Inactivation Methods","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/low-temperature-sterilization","display_name":"low-temperature sterilization","score":0.9990000128746033},{"id":"https://openalex.org/keywords/ethylene-oxide-sterilization","display_name":"ethylene oxide sterilization","score":0.9380000233650208},{"id":"https://openalex.org/keywords/plasma-sterilization","display_name":"plasma sterilization","score":0.8970000147819519},{"id":"https://openalex.org/keywords/chlorofluorocarbon-alternatives","display_name":"chlorofluorocarbon alternatives","score":0.7850000262260437},{"id":"https://openalex.org/keywords/infection-control","display_name":"infection control","score":0.578000009059906},{"id":"https://openalex.org/keywords/resistant-microorganisms","display_name":"resistant microorganisms","score":0.48100000619888306}],"concepts":[{"id":"https://openalex.org/C148761745","wikidata":"https://www.wikidata.org/wiki/Q1563203","display_name":"Sterilization (economics)","level":4,"score":0.8187875747680664},{"id":"https://openalex.org/C2777309684","wikidata":"https://www.wikidata.org/wiki/Q375140","display_name":"Peracetic acid","level":3,"score":0.7856050729751587},{"id":"https://openalex.org/C138944611","wikidata":"https://www.wikidata.org/wiki/Q1163287","display_name":"Clearance","level":2,"score":0.7597209215164185},{"id":"https://openalex.org/C3018890749","wikidata":"https://www.wikidata.org/wiki/Q204711","display_name":"Food and drug administration","level":2,"score":0.5951251983642578},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.35460418462753296},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34988561272621155},{"id":"https://openalex.org/C39432304","wikidata":"https://www.wikidata.org/wiki/Q188847","display_name":"Environmental science","level":0,"score":0.328906774520874},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3285706639289856},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.1792393922805786},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.14107778668403625},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.09501293301582336},{"id":"https://openalex.org/C536366893","wikidata":"https://www.wikidata.org/wiki/Q66076","display_name":"Foreign exchange market","level":3,"score":0.0},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.0},{"id":"https://openalex.org/C533411734","wikidata":"https://www.wikidata.org/wiki/Q171877","display_name":"Hydrogen peroxide","level":2,"score":0.0},{"id":"https://openalex.org/C2776988154","wikidata":"https://www.wikidata.org/wiki/Q66100","display_name":"Exchange rate","level":2,"score":0.0},{"id":"https://openalex.org/C10138342","wikidata":"https://www.wikidata.org/wiki/Q43015","display_name":"Finance","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002495","descriptor_name":"Central Supply, Hospital","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012997","descriptor_name":"Solvents","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D013242","descriptor_name":"Sterilization","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D013242","descriptor_name":"Sterilization","qualifier_ui":"Q000592","qualifier_name":"standards","is_major_topic":true},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D014481","descriptor_name":"United States","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014486","descriptor_name":"United States Food and Drug Administration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1086/647730","doi":"https://doi.org/10.1086/647730","is_oa":false,"landing_page_url":"https://doi.org/10.1086/647730","pdf_url":null,"source":{"id":"https://openalex.org/S129764719","display_name":"Infection Control and Hospital Epidemiology","issn_l":"0899-823X","issn":["0899-823X","1559-6834"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection Control & Hospital Epidemiology","raw_type":"journal-article"},{"id":"doi:10.2307/30141431","doi":"https://doi.org/10.2307/30141431","is_oa":false,"landing_page_url":"https://doi.org/10.2307/30141431","pdf_url":null,"source":{"id":"https://openalex.org/S129764719","display_name":"Infection Control and Hospital Epidemiology","issn_l":"0899-823X","issn":["0899-823X","1559-6834"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection Control and Hospital Epidemiology","raw_type":"journal-article"},{"id":"pmid:9801294","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9801294","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Infection control and hospital epidemiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9074000120162964,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1945195617","https://openalex.org/W1977585431","https://openalex.org/W2004671532","https://openalex.org/W2016608299","https://openalex.org/W2029838459","https://openalex.org/W2036783533","https://openalex.org/W2047617024","https://openalex.org/W2085884043","https://openalex.org/W2133252215","https://openalex.org/W2139186732","https://openalex.org/W2148012650","https://openalex.org/W2242009113","https://openalex.org/W2401027624","https://openalex.org/W2423468481","https://openalex.org/W3021129713","https://openalex.org/W4255999189","https://openalex.org/W4299093287","https://openalex.org/W4299585602","https://openalex.org/W6690521542"],"related_works":["https://openalex.org/W2133252215","https://openalex.org/W1966558339","https://openalex.org/W2473843077","https://openalex.org/W4298934816","https://openalex.org/W2184575921","https://openalex.org/W2916928438","https://openalex.org/W4287911794","https://openalex.org/W2461883803","https://openalex.org/W2141316716","https://openalex.org/W2242009113"],"abstract_inverted_index":{"The":[0,41],"elimination":[1],"of":[2,14,57,90],"chlorofluorocarbons":[3],"by":[4],"the":[5,12,21,53,69,74],"Clean":[6],"Air":[7],"Act":[8],"has":[9],"led":[10],"to":[11,65],"development":[13],"alternative":[15],"technologies":[16,83],"for":[17],"low-temperature":[18,81],"sterilization":[19,82],"in":[20,35],"healthcare":[22],"setting,":[23],"including":[24],"100%":[25],"ethylene":[26,28],"oxide,":[27],"oxide":[29],"with":[30,63],"other":[31],"stabilizing":[32],"gases,":[33],"immersion":[34],"peracetic":[36],"acid,":[37],"and":[38,47,55,78],"gas":[39],"plasmas.":[40],"ideal":[42],"sterilant":[43],"does":[44],"not":[45],"exist,":[46],"infection":[48],"control":[49],"professionals":[50],"should":[51],"understand":[52],"advantages":[54],"disadvantages":[56],"these":[58],"processes.":[59],"However,":[60],"when":[61],"combined":[62],"adherence":[64],"standard":[66],"cleaning":[67],"protocols,":[68],"available":[70,76],"data":[71],"suggest":[72],"that":[73],"currently":[75],"Food":[77],"Drug":[79],"Administration-cleared":[80],"can":[84],"inactivate":[85],"a":[86],"clinically":[87],"relevant":[88],"inoculum":[89],"highly":[91],"resistant":[92],"organisms.":[93]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}