{"id":"https://openalex.org/W2032566097","doi":"https://doi.org/10.1016/0006-8993(90)91368-q","title":"Regulation of neurotensin-containing neurons in the rat striatum and substantia nigra. Effects of unilateral nigral lesion with 6-hydroxydopamine on neurotensin content and its binding site density","display_name":"Regulation of neurotensin-containing neurons in the rat striatum and substantia nigra. Effects of unilateral nigral lesion with 6-hydroxydopamine on neurotensin content and its binding site density","publication_year":1990,"publication_date":"1990-03-01","ids":{"openalex":"https://openalex.org/W2032566097","doi":"https://doi.org/10.1016/0006-8993(90)91368-q","mag":"2032566097","pmid":"https://pubmed.ncbi.nlm.nih.gov/1970504"},"language":"en","primary_location":{"id":"doi:10.1016/0006-8993(90)91368-q","doi":"https://doi.org/10.1016/0006-8993(90)91368-q","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0006-8993(90)91368-q","pdf_url":null,"source":{"id":"https://openalex.org/S96638545","display_name":"Brain Research","issn_l":"0006-8993","issn":["0006-8993","1872-6240"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5034496794","display_name":"Yoshinori Masuo","orcid":"https://orcid.org/0000-0003-3832-7984","observed_orcids":["https://orcid.org/0000-0003-3832-7984"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4405276790","display_name":"Unit\u00e9 de Recherches sur les Peptides Neurodigestifs et le Diab\u00e8te","ror":"https://ror.org/00ag6p996","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405276790"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Yoshinori Masuo","raw_affiliation_strings":["I.N.S.E.R.M. U.55, H\u00f4pital Saint-Antoine, Saint Antoine, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I.N.S.E.R.M. U.55, H\u00f4pital Saint-Antoine, Saint Antoine, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210102928","https://openalex.org/I4405276790"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088092447","display_name":"Didier P\u00e9laprat","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4405276790","display_name":"Unit\u00e9 de Recherches sur les Peptides Neurodigestifs et le Diab\u00e8te","ror":"https://ror.org/00ag6p996","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405276790"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Didier P\u00e9laprat","raw_affiliation_strings":["I.N.S.E.R.M. U.55, Ho\u02c6pital Saint-Antoine, Saint-Antoine, Paris France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I.N.S.E.R.M. U.55, Ho\u02c6pital Saint-Antoine, Saint-Antoine, Paris France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210102928","https://openalex.org/I4405276790"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000711726","display_name":"Marie\u2010No\u00eblle Montagne","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4405276790","display_name":"Unit\u00e9 de Recherches sur les Peptides Neurodigestifs et le Diab\u00e8te","ror":"https://ror.org/00ag6p996","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405276790"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Marie-No\u00eblle Montagne","raw_affiliation_strings":["I.N.S.E.R.M. U.55, Ho\u02c6pital Saint-Antoine, Saint-Antoine, Paris France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I.N.S.E.R.M. U.55, Ho\u02c6pital Saint-Antoine, Saint-Antoine, Paris France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210102928","https://openalex.org/I4405276790"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050044807","display_name":"Daniel Scherman","orcid":"https://orcid.org/0000-0003-1207-1298","observed_orcids":["https://orcid.org/0000-0003-1207-1298","https://orcid.org/0000-0003-1742-9340"]},"institutions":[{"id":"https://openalex.org/I4210107423","display_name":"Institut de Biologie Physico-Chimique","ror":"https://ror.org/01na0pb61","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I4210096427","https://openalex.org/I4210107423"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Daniel Scherman","raw_affiliation_strings":["Unit\u00e9C.N.R.S. de Neurobiologie Physico-Chimique, Institut de Biologie Physico-Chimique, Paris France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Unit\u00e9C.N.R.S. de Neurobiologie Physico-Chimique, Institut de Biologie Physico-Chimique, Paris France","institution_ids":["https://openalex.org/I4210107423"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070820842","display_name":"William H. Rost\u00e8ne","orcid":"https://orcid.org/0000-0003-0409-5361","observed_orcids":["https://orcid.org/0000-0003-0409-5361"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210102928","display_name":"H\u00f4pital Saint-Antoine","ror":"https://ror.org/01875pg84","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210102928"]},{"id":"https://openalex.org/I4405276790","display_name":"Unit\u00e9 de Recherches sur les Peptides Neurodigestifs et le Diab\u00e8te","ror":"https://ror.org/00ag6p996","country_code":"FR","type":"facility","lineage":["https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4405264447","https://openalex.org/I4405276790"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"William Rost\u00e8ne","raw_affiliation_strings":["I.N.S.E.R.M. U.55, Ho\u02c6pital Saint-Antoine, Saint-Antoine, Paris France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I.N.S.E.R.M. U.55, Ho\u02c6pital Saint-Antoine, Saint-Antoine, Paris France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210102928","https://openalex.org/I4405276790"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5034496794"],"corresponding_institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210102928","https://openalex.org/I4405276790"],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":2.3771,"has_fulltext":false,"cited_by_count":41,"citation_normalized_percentile":{"value":0.89386755,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"510","issue":"2","first_page":"203","last_page":"210"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.5630000233650208,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10814","display_name":"Neuropeptides and Animal Physiology","score":0.5630000233650208,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.20069999992847443,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.15719999372959137,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neurotensin","display_name":"neurotensin","score":1.0},{"id":"https://openalex.org/keywords/substantia-nigra","display_name":"substantia nigra","score":0.8840000033378601},{"id":"https://openalex.org/keywords/striatum","display_name":"striatum","score":0.9850000143051147},{"id":"https://openalex.org/keywords/6-ohda-lesion","display_name":"6-hydroxydopamine lesion","score":0.9559999704360962},{"id":"https://openalex.org/keywords/dopaminergic-neurons","display_name":"dopaminergic neurons","score":0.7490000128746033},{"id":"https://openalex.org/keywords/tyrosine-hydroxylase","display_name":"tyrosine hydroxylase","score":0.8880000114440918},{"id":"https://openalex.org/keywords/dopamine-d2-receptor","display_name":"dopamine D2 receptor","score":0.753000020980835},{"id":"https://openalex.org/keywords/dihydrotetrabenazine","display_name":"dihydrotetrabenazine","score":0.9549999833106995},{"id":"https://openalex.org/keywords/gaba","display_name":"GABA","score":0.8429999947547913}],"concepts":[{"id":"https://openalex.org/C2780938664","wikidata":"https://www.wikidata.org/wiki/Q753278","display_name":"Substantia nigra","level":4,"score":0.9567590951919556},{"id":"https://openalex.org/C2780062018","wikidata":"https://www.wikidata.org/wiki/Q1319792","display_name":"Striatum","level":3,"score":0.846676766872406},{"id":"https://openalex.org/C2778976297","wikidata":"https://www.wikidata.org/wiki/Q419576","display_name":"Neurotensin","level":4,"score":0.7577271461486816},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.7097666263580322},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.7006160020828247},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6393961906433105},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6128302216529846},{"id":"https://openalex.org/C2776355744","wikidata":"https://www.wikidata.org/wiki/Q4318555","display_name":"Nigrostriatal pathway","level":5,"score":0.5398008823394775},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.49336162209510803},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3618980050086975},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.3337336778640747},{"id":"https://openalex.org/C118303440","wikidata":"https://www.wikidata.org/wiki/Q419968","display_name":"Neuropeptide","level":3,"score":0.2498418688774109},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.19216439127922058},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10889998078346252}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003342","descriptor_name":"Corpus Striatum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004298","descriptor_name":"Dopamine","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D006892","descriptor_name":"Hydroxydopamines","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007839","descriptor_name":"Functional Laterality","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009496","descriptor_name":"Neurotensin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009498","descriptor_name":"Neurotoxins","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D011919","descriptor_name":"Rats, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011954","descriptor_name":"Receptors, Dopamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013378","descriptor_name":"Substantia Nigra","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D013378","descriptor_name":"Substantia Nigra","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014446","descriptor_name":"Tyrosine 3-Monooxygenase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016627","descriptor_name":"Oxidopamine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017981","descriptor_name":"Receptors, Neurotransmitter","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018028","descriptor_name":"Receptors, Neurotensin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0006-8993(90)91368-q","doi":"https://doi.org/10.1016/0006-8993(90)91368-q","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0006-8993(90)91368-q","pdf_url":null,"source":{"id":"https://openalex.org/S96638545","display_name":"Brain Research","issn_l":"0006-8993","issn":["0006-8993","1872-6240"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doyens","erih-plus","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain Research","raw_type":"journal-article"},{"id":"pmid:1970504","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1970504","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Brain research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":51,"referenced_works":["https://openalex.org/W221359381","https://openalex.org/W249845531","https://openalex.org/W1487686100","https://openalex.org/W1497427077","https://openalex.org/W1498891976","https://openalex.org/W1905940192","https://openalex.org/W1964535311","https://openalex.org/W1971501196","https://openalex.org/W1972948684","https://openalex.org/W1975961987","https://openalex.org/W1976116089","https://openalex.org/W1976962285","https://openalex.org/W1980092325","https://openalex.org/W1988041304","https://openalex.org/W1988226656","https://openalex.org/W1993534035","https://openalex.org/W1995194650","https://openalex.org/W1997839253","https://openalex.org/W2002886681","https://openalex.org/W2007247016","https://openalex.org/W2007835337","https://openalex.org/W2015545832","https://openalex.org/W2017968099","https://openalex.org/W2024762380","https://openalex.org/W2027675670","https://openalex.org/W2028412969","https://openalex.org/W2031020962","https://openalex.org/W2041110976","https://openalex.org/W2043393596","https://openalex.org/W2047251988","https://openalex.org/W2052924733","https://openalex.org/W2055715560","https://openalex.org/W2063527942","https://openalex.org/W2067678628","https://openalex.org/W2068031892","https://openalex.org/W2071774239","https://openalex.org/W2076291793","https://openalex.org/W2077955240","https://openalex.org/W2080627371","https://openalex.org/W2081600178","https://openalex.org/W2081610407","https://openalex.org/W2084026761","https://openalex.org/W2084417519","https://openalex.org/W2091129282","https://openalex.org/W2128635872","https://openalex.org/W2133176740","https://openalex.org/W2154254956","https://openalex.org/W2163815564","https://openalex.org/W2287619106","https://openalex.org/W2294946349","https://openalex.org/W2350518191"],"related_works":["https://openalex.org/W1971501196","https://openalex.org/W2064086944","https://openalex.org/W1983852315","https://openalex.org/W2440425201","https://openalex.org/W2022516265","https://openalex.org/W2001570324","https://openalex.org/W2413334150","https://openalex.org/W2050505239","https://openalex.org/W1978409622","https://openalex.org/W1998532128"],"abstract_inverted_index":null,"counts_by_year":[{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}