{"id":"https://openalex.org/W2032470169","doi":"https://doi.org/10.1016/0026-0495(84)90016-7","title":"Failure of bromocriptine to alter the qualitative characteristics of human growth hormone in acromegaly","display_name":"Failure of bromocriptine to alter the qualitative characteristics of human growth hormone in acromegaly","publication_year":1984,"publication_date":"1984-06-01","ids":{"openalex":"https://openalex.org/W2032470169","doi":"https://doi.org/10.1016/0026-0495(84)90016-7","mag":"2032470169","pmid":"https://pubmed.ncbi.nlm.nih.gov/6727657"},"language":"en","primary_location":{"id":"doi:10.1016/0026-0495(84)90016-7","doi":"https://doi.org/10.1016/0026-0495(84)90016-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0026-0495(84)90016-7","pdf_url":null,"source":{"id":"https://openalex.org/S119661813","display_name":"Metabolism","issn_l":"0026-0495","issn":["0026-0495","1532-8600"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolism","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012129165","display_name":"Naomi Hizuka","orcid":"https://orcid.org/0009-0006-4153-1766","observed_orcids":["https://orcid.org/0009-0006-4153-1766"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Naomi Hizuka","raw_affiliation_strings":["Diabetes Branch, National Institute of Arthritis, Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes Branch, National Institute of Arthritis, Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074369996","display_name":"CARLA M. HENDRICKS","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carla M. Hendricks","raw_affiliation_strings":["Diabetes Branch, National Institute of Arthritis, Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes Branch, National Institute of Arthritis, Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112097822","display_name":"Jesse Roth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jesse Roth","raw_affiliation_strings":["Diabetes Branch, National Institute of Arthritis, Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes Branch, National Institute of Arthritis, Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070064147","display_name":"Phillip G\u00f6rden","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210090567","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Phillip Gorden","raw_affiliation_strings":["Diabetes Branch, National Institute of Arthritis, Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Diabetes Branch, National Institute of Arthritis, Diabetes, Digestive, and Kidney Diseases, National Institutes of Health, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5070064147"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210090567"],"apc_list":{"value":5340,"currency":"USD","value_usd":5340},"apc_paid":null,"fwci":0.6803,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.69793621,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"33","issue":"6","first_page":"582","last_page":"584"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.8515999913215637,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10832","display_name":"Pituitary Gland Disorders and Treatments","score":0.8515999913215637,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10748","display_name":"Growth Hormone and Insulin-like Growth Factors","score":0.1477999985218048,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10754","display_name":"Neuroendocrine Tumor Research Advances","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bromocriptine","display_name":"bromocriptine","score":0.9890000224113464},{"id":"https://openalex.org/keywords/acromegaly","display_name":"acromegaly","score":0.996999979019165},{"id":"https://openalex.org/keywords/human-growth-hormone","display_name":"human growth hormone","score":0.9829999804496765},{"id":"https://openalex.org/keywords/growth-hormone-receptor","display_name":"growth hormone receptor","score":0.7480000257492065},{"id":"https://openalex.org/keywords/radioreceptor-assay","display_name":"radioreceptor assay","score":0.7310000061988831},{"id":"https://openalex.org/keywords/radioimmunoassay","display_name":"radioimmunoassay","score":0.9309999942779541}],"concepts":[{"id":"https://openalex.org/C2776856834","wikidata":"https://www.wikidata.org/wiki/Q413581","display_name":"Bromocriptine","level":4,"score":0.992419958114624},{"id":"https://openalex.org/C2777433750","wikidata":"https://www.wikidata.org/wiki/Q189580","display_name":"Acromegaly","level":4,"score":0.9547127485275269},{"id":"https://openalex.org/C176685330","wikidata":"https://www.wikidata.org/wiki/Q857638","display_name":"Radioimmunoassay","level":2,"score":0.7212796211242676},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6634528636932373},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6189185380935669},{"id":"https://openalex.org/C163994747","wikidata":"https://www.wikidata.org/wiki/Q2916358","display_name":"Sephadex","level":3,"score":0.5487951040267944},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.496265709400177},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4768158793449402},{"id":"https://openalex.org/C3020134792","wikidata":"https://www.wikidata.org/wiki/Q79749","display_name":"Human plasma","level":2,"score":0.47595807909965515},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.43958359956741333},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.41570985317230225},{"id":"https://openalex.org/C2984496839","wikidata":"https://www.wikidata.org/wiki/Q29956617","display_name":"Growth hormone","level":3,"score":0.39136597514152527},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3568226099014282},{"id":"https://openalex.org/C2779064019","wikidata":"https://www.wikidata.org/wiki/Q66590068","display_name":"Prolactin","level":3,"score":0.1842339038848877},{"id":"https://openalex.org/C43617362","wikidata":"https://www.wikidata.org/wiki/Q170050","display_name":"Chromatography","level":1,"score":0.18054473400115967},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0909515917301178},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.08769816160202026}],"mesh":[{"descriptor_ui":"D000172","descriptor_name":"Acromegaly","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000172","descriptor_name":"Acromegaly","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001971","descriptor_name":"Bromocriptine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008214","descriptor_name":"Lymphocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011863","descriptor_name":"Radioimmunoassay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011869","descriptor_name":"Radioligand Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013006","descriptor_name":"Growth Hormone","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/0026-0495(84)90016-7","doi":"https://doi.org/10.1016/0026-0495(84)90016-7","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0026-0495(84)90016-7","pdf_url":null,"source":{"id":"https://openalex.org/S119661813","display_name":"Metabolism","issn_l":"0026-0495","issn":["0026-0495","1532-8600"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolism","raw_type":"journal-article"},{"id":"pmid:6727657","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6727657","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Metabolism: clinical and experimental","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":11,"referenced_works":["https://openalex.org/W625136540","https://openalex.org/W1974152523","https://openalex.org/W1985882460","https://openalex.org/W2006522802","https://openalex.org/W2052910600","https://openalex.org/W2066039214","https://openalex.org/W2091782256","https://openalex.org/W2146342121","https://openalex.org/W2396841882","https://openalex.org/W2435448884","https://openalex.org/W2467232259"],"related_works":["https://openalex.org/W2053041562","https://openalex.org/W2006522802","https://openalex.org/W1994166680","https://openalex.org/W1973838654","https://openalex.org/W1990931000","https://openalex.org/W4229649688","https://openalex.org/W2109230861","https://openalex.org/W1999795951","https://openalex.org/W4248025059","https://openalex.org/W1984497973"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}