{"id":"https://openalex.org/W2032276409","doi":"https://doi.org/10.1016/j.bone.2009.01.467","title":"Skeletal dysplasia and lethality in mice lacking the mid-region, nuclear localization signal and C-terminus of parathyroid hormone-related protein","display_name":"Skeletal dysplasia and lethality in mice lacking the mid-region, nuclear localization signal and C-terminus of parathyroid hormone-related protein","publication_year":2009,"publication_date":"2009-03-25","ids":{"openalex":"https://openalex.org/W2032276409","doi":"https://doi.org/10.1016/j.bone.2009.01.467","mag":"2032276409"},"language":"en","primary_location":{"id":"doi:10.1016/j.bone.2009.01.467","doi":"https://doi.org/10.1016/j.bone.2009.01.467","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bone.2009.01.467","pdf_url":null,"source":{"id":"https://openalex.org/S121725775","display_name":"Bone","issn_l":"1873-2763","issn":["1873-2763","8756-3282"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bone","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028812716","display_name":"Ramiro E. Toribio","orcid":"https://orcid.org/0000-0002-9063-540X","observed_orcids":["https://orcid.org/0000-0002-9063-540X"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R.E. Toribio","raw_affiliation_strings":["Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio, United States","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":null,"display_name":"H.A. Brown","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"H.A. Brown","raw_affiliation_strings":["Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Veterinary Clinical Sciences, The Ohio State University, Columbus, Ohio, United States","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066323693","display_name":"Chad M. Novince","orcid":"https://orcid.org/0000-0002-0318-7494","observed_orcids":["https://orcid.org/0000-0002-0318-7494"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C.M. Novince","raw_affiliation_strings":["Periodontics and Oral Medicine, University of Michigan, Ann Arbor, Michigan, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Periodontics and Oral Medicine, University of Michigan, Ann Arbor, Michigan, United States","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025655551","display_name":"Lisa G. Lanigan","orcid":"https://orcid.org/0000-0001-8969-7411","observed_orcids":["https://orcid.org/0000-0001-8969-7411"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L.G. Lanigan","raw_affiliation_strings":["Veterinary Biosciences, The Ohio State University, Columbus, Ohio, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Veterinary Biosciences, The Ohio State University, Columbus, Ohio, United States","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029781288","display_name":"Jillian L. Werbeck","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J.L. Werbeck","raw_affiliation_strings":["Veterinary Biosciences, The Ohio State University, Columbus, Ohio, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Veterinary Biosciences, The Ohio State University, Columbus, Ohio, United States","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108380593","display_name":"S Shu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S.T. Shu","raw_affiliation_strings":["Veterinary Biosciences, The Ohio State University, Columbus, Ohio, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Veterinary Biosciences, The Ohio State University, Columbus, Ohio, United States","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050400853","display_name":"Gwendolen Lorch","orcid":"https://orcid.org/0000-0001-6443-704X","observed_orcids":["https://orcid.org/0000-0001-6443-704X"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G. Lorch","raw_affiliation_strings":["Veterinary Biosciences, The Ohio State University, Columbus, Ohio, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Veterinary Biosciences, The Ohio State University, Columbus, Ohio, United States","institution_ids":["https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029314163","display_name":"John Foley","orcid":"https://orcid.org/0000-0003-0266-8488","observed_orcids":["https://orcid.org/0000-0003-0266-8488"]},"institutions":[{"id":"https://openalex.org/I4210119109","display_name":"Indiana University Bloomington","ror":"https://ror.org/02k40bc56","country_code":"US","type":"education","lineage":["https://openalex.org/I4210119109","https://openalex.org/I592451"]},{"id":"https://openalex.org/I592451","display_name":"Indiana University","ror":"https://ror.org/01kg8sb98","country_code":"US","type":"education","lineage":["https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J. Foley","raw_affiliation_strings":["Medical Sciences Program, Indiana University, Bloomington, Indiana, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Sciences Program, Indiana University, Bloomington, Indiana, United States","institution_ids":["https://openalex.org/I4210119109","https://openalex.org/I592451"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010672369","display_name":"Laurie K. McCauley","orcid":"https://orcid.org/0000-0001-9173-9123","observed_orcids":["https://orcid.org/0000-0001-9173-9123"]},"institutions":[{"id":"https://openalex.org/I27837315","display_name":"University of Michigan","ror":"https://ror.org/00jmfr291","country_code":"US","type":"education","lineage":["https://openalex.org/I27837315"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"L.K. McCauley","raw_affiliation_strings":["Periodontics and Oral Medicine, University of Michigan, Ann Arbor, Michigan, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Periodontics and Oral Medicine, University of Michigan, Ann Arbor, Michigan, United States","institution_ids":["https://openalex.org/I27837315"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035821309","display_name":"Thomas J. Rosol","orcid":"https://orcid.org/0000-0003-3737-1190","observed_orcids":["https://orcid.org/0000-0003-3737-1190"]},"institutions":[{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T.J. Rosol","raw_affiliation_strings":["Veterinary Biosciences, The Ohio State University, Columbus, Ohio, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Veterinary Biosciences, The Ohio State University, Columbus, Ohio, United States","institution_ids":["https://openalex.org/I52357470"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3960,"currency":"USD","value_usd":3960},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.13608619,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"44","issue":null,"first_page":"S53","last_page":"S53"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.6420999765396118,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.6420999765396118,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":0.2207999974489212,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.09549999982118607,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/parathyroid-hormone-related-protein","display_name":"parathyroid hormone-related protein","score":0.9589999914169312},{"id":"https://openalex.org/keywords/skeletal-dysplasia","display_name":"skeletal dysplasia","score":0.8610000014305115},{"id":"https://openalex.org/keywords/lethality","display_name":"lethality","score":0.9639999866485596},{"id":"https://openalex.org/keywords/mice","display_name":"mice","score":0.5059999823570251},{"id":"https://openalex.org/keywords/bone-marrow-adipogenesis","display_name":"bone marrow adipogenesis","score":0.6499999761581421},{"id":"https://openalex.org/keywords/risedronate","display_name":"risedronate","score":0.8330000042915344},{"id":"https://openalex.org/keywords/bisphosphonates","display_name":"bisphosphonates","score":0.972000002861023},{"id":"https://openalex.org/keywords/postmenopausal-osteoporosis","display_name":"postmenopausal osteoporosis","score":0.9819999933242798},{"id":"https://openalex.org/keywords/osteoblastogenesis","display_name":"osteoblastogenesis","score":0.6800000071525574},{"id":"https://openalex.org/keywords/adipogenic-differentiation","display_name":"adipogenesis","score":0.5590000152587891},{"id":"https://openalex.org/keywords/bone-loss","display_name":"bone loss","score":0.5070000290870667},{"id":"https://openalex.org/keywords/age-related-bone-loss","display_name":"age-related bone loss","score":0.7020000219345093},{"id":"https://openalex.org/keywords/mesenchymal-stem-cells","display_name":"mesenchymal stem cells","score":0.7929999828338623},{"id":"https://openalex.org/keywords/transiliac-bone-biopsy","display_name":"transiliac bone biopsy","score":0.7139999866485596},{"id":"https://openalex.org/keywords/adipocyte-size","display_name":"adipocyte size","score":0.4729999899864197}],"concepts":[{"id":"https://openalex.org/C2776175234","wikidata":"https://www.wikidata.org/wiki/Q357519","display_name":"Adipocyte","level":3,"score":0.7767072916030884},{"id":"https://openalex.org/C122927707","wikidata":"https://www.wikidata.org/wiki/Q2824461","display_name":"Adipogenesis","level":3,"score":0.7640748023986816},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6584247946739197},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6331610679626465},{"id":"https://openalex.org/C2778260815","wikidata":"https://www.wikidata.org/wiki/Q917177","display_name":"Osteoblast","level":3,"score":0.6292939186096191},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6092867255210876},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.5080153942108154},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.5040284991264343},{"id":"https://openalex.org/C2780007613","wikidata":"https://www.wikidata.org/wiki/Q546523","display_name":"Bone marrow","level":2,"score":0.4952003061771393},{"id":"https://openalex.org/C1008401","wikidata":"https://www.wikidata.org/wiki/Q184681","display_name":"Anabolism","level":2,"score":0.4701820909976959},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.45625385642051697},{"id":"https://openalex.org/C2781208988","wikidata":"https://www.wikidata.org/wiki/Q202476","display_name":"Parathyroid hormone","level":3,"score":0.43667811155319214},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.21737870573997498},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.21345704793930054},{"id":"https://openalex.org/C171089720","wikidata":"https://www.wikidata.org/wiki/Q193583","display_name":"Adipose tissue","level":2,"score":0.13883385062217712},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.10923627018928528},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.10189467668533325},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.05026519298553467},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.bone.2009.01.467","doi":"https://doi.org/10.1016/j.bone.2009.01.467","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bone.2009.01.467","pdf_url":null,"source":{"id":"https://openalex.org/S121725775","display_name":"Bone","issn_l":"1873-2763","issn":["1873-2763","8756-3282"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Bone","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9922999739646912,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.8299999833106995,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2006296519","https://openalex.org/W1993515428","https://openalex.org/W2987981770","https://openalex.org/W2001706530","https://openalex.org/W3174010255","https://openalex.org/W4402554975","https://openalex.org/W2004675263","https://openalex.org/W6946273278","https://openalex.org/W2003197644","https://openalex.org/W1536179852"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2016-06-24T00:00:00"}