{"id":"https://openalex.org/W2032217751","doi":"https://doi.org/10.4088/pcc.10br01104","title":"Association of Attention-Deficit/Hyperactivity Disorder and Celiac Disease","display_name":"Association of Attention-Deficit/Hyperactivity Disorder and Celiac Disease","publication_year":2011,"publication_date":"2011-06-15","ids":{"openalex":"https://openalex.org/W2032217751","doi":"https://doi.org/10.4088/pcc.10br01104","mag":"2032217751","pmid":"https://pubmed.ncbi.nlm.nih.gov/21977364","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3184556"},"language":"en","primary_location":{"id":"doi:10.4088/pcc.10br01104","doi":"https://doi.org/10.4088/pcc.10br01104","is_oa":false,"landing_page_url":"https://doi.org/10.4088/pcc.10br01104","pdf_url":null,"source":{"id":"https://openalex.org/S4210179967","display_name":"The Primary Care Companion For CNS Disorders","issn_l":"2155-7772","issn":["2155-7772","2155-7780"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","medline","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4322614534","host_organization_name":"Physicians Postgraduate Press, Inc.","host_organization_lineage":["https://openalex.org/P4322614534"],"host_organization_lineage_names":["Physicians Postgraduate Press, Inc."],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Primary Care Companion For CNS Disorders","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3184556","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110392091","display_name":"Helmut Niederhofer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210142017","display_name":"S\u00e4chsisches Krankenhaus Rodewisch","ror":"https://ror.org/044s59k57","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I4210142017"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Helmut Niederhofer","raw_affiliation_strings":["Department of Child Psychiatry, Psychiatric Hospital of Rodewisch, Rodewisch, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Child Psychiatry, Psychiatric Hospital of Rodewisch, Rodewisch, Germany","institution_ids":["https://openalex.org/I4210142017"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5110392091"],"corresponding_institution_ids":["https://openalex.org/I4210142017"],"apc_list":null,"apc_paid":null,"fwci":2.0644,"has_fulltext":false,"cited_by_count":57,"citation_normalized_percentile":{"value":0.86538642,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"13","issue":"3","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11348","display_name":"Celiac Disease Research and Management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11348","display_name":"Celiac Disease Research and Management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10537","display_name":"Attention Deficit Hyperactivity Disorder","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10106","display_name":"Autism Spectrum Disorder Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/attention-deficit-hyperactivity-disorder","display_name":"attention deficit hyperactivity disorder","score":0.9359999895095825},{"id":"https://openalex.org/keywords/celiac-disease","display_name":"celiac disease","score":1.0},{"id":"https://openalex.org/keywords/gluten-free-diet","display_name":"gluten-free diet","score":0.9990000128746033},{"id":"https://openalex.org/keywords/behavioral-symptoms","display_name":"behavioral symptoms","score":0.8370000123977661},{"id":"https://openalex.org/keywords/anti-endomysial-antibodies","display_name":"anti-endomysial antibodies","score":0.6819999814033508},{"id":"https://openalex.org/keywords/psychiatric-comorbidity","display_name":"psychiatric comorbidity","score":0.6629999876022339},{"id":"https://openalex.org/keywords/children-and-adolescents","display_name":"children and adolescents","score":0.4440000057220459}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.741485595703125},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.7028125524520874},{"id":"https://openalex.org/C2779356329","wikidata":"https://www.wikidata.org/wiki/Q922625","display_name":"Checklist","level":2,"score":0.6330162286758423},{"id":"https://openalex.org/C2776336767","wikidata":"https://www.wikidata.org/wiki/Q188251","display_name":"Gluten","level":2,"score":0.5851148366928101},{"id":"https://openalex.org/C3019118998","wikidata":"https://www.wikidata.org/wiki/Q2632776","display_name":"Gluten free","level":3,"score":0.5422462224960327},{"id":"https://openalex.org/C2780783007","wikidata":"https://www.wikidata.org/wiki/Q181923","display_name":"Attention deficit hyperactivity disorder","level":2,"score":0.5137449502944946},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4850849211215973},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.37509891390800476},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.3658207952976227},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.32073238492012024},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.1659633219242096},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.06909006834030151},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.4088/pcc.10br01104","doi":"https://doi.org/10.4088/pcc.10br01104","is_oa":false,"landing_page_url":"https://doi.org/10.4088/pcc.10br01104","pdf_url":null,"source":{"id":"https://openalex.org/S4210179967","display_name":"The Primary Care Companion For CNS Disorders","issn_l":"2155-7772","issn":["2155-7772","2155-7780"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","medline","poland-20","russia-white-list-3"],"host_organization":"https://openalex.org/P4322614534","host_organization_name":"Physicians Postgraduate Press, Inc.","host_organization_lineage":["https://openalex.org/P4322614534"],"host_organization_lineage_names":["Physicians Postgraduate Press, Inc."],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Primary Care Companion For CNS Disorders","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:2191952","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3184556","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3184556","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3184556","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Prim Care Companion CNS Disord","raw_type":"Text"},{"id":"pmid:21977364","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21977364","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The primary care companion for CNS disorders","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2191952","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3184556","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W11202700","https://openalex.org/W98985426","https://openalex.org/W99459975","https://openalex.org/W1522458188","https://openalex.org/W1847537772","https://openalex.org/W1966969803","https://openalex.org/W1968637619","https://openalex.org/W1973288987","https://openalex.org/W1985764811","https://openalex.org/W1991013976","https://openalex.org/W1994611578","https://openalex.org/W1998775876","https://openalex.org/W2015145221","https://openalex.org/W2016152913","https://openalex.org/W2026003472","https://openalex.org/W2035618291","https://openalex.org/W2062353129","https://openalex.org/W2091518539","https://openalex.org/W2098567963","https://openalex.org/W2109582866","https://openalex.org/W2136681439","https://openalex.org/W2138803074","https://openalex.org/W2151550314","https://openalex.org/W2157630316","https://openalex.org/W2162196677","https://openalex.org/W2165967591","https://openalex.org/W2331797066","https://openalex.org/W2334753153","https://openalex.org/W3035715270"],"related_works":["https://openalex.org/W2109582866","https://openalex.org/W4315797258","https://openalex.org/W2925911883","https://openalex.org/W2273727456","https://openalex.org/W4281565027","https://openalex.org/W2320002159","https://openalex.org/W4292099940","https://openalex.org/W7166098464","https://openalex.org/W3111415948","https://openalex.org/W2220318873"],"abstract_inverted_index":{"OBJECTIVE:":[0],"A":[1,108,194],"possible":[2,99],"association":[3],"of":[4,23,93,139],"celiac":[5,41,100,119,135,161,204,214],"disease":[6,42,101,185,205,215],"with":[7,40,57,122,129,192,203],"psychiatric":[8],"and":[9,43,80,105,154,163],"psychological":[10],"disturbances":[11],"such":[12],"as":[13],"attention-deficit/hyperactivity":[14],"disorder":[15],"(ADHD)":[16],"has":[17],"been":[18],"reported":[19,147],"repeatedly.":[20],"The":[21,209],"objective":[22],"this":[24,207],"study":[25,63],"was":[26,83,111,166],"to":[27,50,70,85,157],"observe":[28],"whether":[29],"a":[30,148],"gluten-free":[31,109,141,195],"diet":[32,110,196],"could":[33],"alleviate":[34],"the":[35,62,126,140,158,169,174,220],"behavioral":[36],"symptoms":[37,200],"in":[38,61,64,118,151,168,201,206,219],"patients":[39,121,128,143,190,202],"ADHD.":[44,123,193],"METHOD:":[45],"Sixty-seven":[46],"subjects":[47,95],"aged":[48],"7":[49],"42":[51],"years":[52],"(mean":[53],"=":[54,178,181],"11.4":[55],"years)":[56],"ADHD":[58,199,221],"were":[59,96,132],"enrolled":[60],"South":[65],"Tyrol,":[66],"Italy,":[67],"from":[68],"2004":[69],"2008.":[71],"Hypescheme,":[72],"an":[73],"operational":[74],"criteria":[75],"checklist":[76],"that":[77,213],"incorporates":[78],"DSM-IV":[79],"ICD-10":[81],"criteria,":[82],"used":[84],"assess":[86],"ADHD-like":[87],"symptomatology.":[88],"Additionally,":[89],"blood":[90],"serum":[91],"levels":[92],"all":[94],"assessed":[97],"for":[98,113,134],"by":[102],"examining":[103],"antigliadine":[104],"antiendomysium":[106],"antibodies.":[107],"initiated":[112],"at":[114],"least":[115],"6":[116],"months":[117],"disease-positive":[120],"RESULTS:":[124],"Of":[125],"67":[127],"ADHD,":[130],"10":[131],"positive":[133],"disease.":[136],"After":[137],"initiation":[138],"diet,":[142],"or":[144],"their":[145,152],"parents":[146],"significant":[149],"improvement":[150],"behavior":[153],"functioning":[155],"compared":[156],"period":[159],"before":[160],"diagnosis":[162],"treatment,":[164],"which":[165],"evident":[167],"overall":[170],"mean":[171],"score":[172],"on":[173],"Hypescheme":[175],"questionnaire":[176],"(t":[177],"4.22,":[179],"P":[180],".023).":[182],"CONCLUSIONS:":[183],"Celiac":[184],"is":[186],"markedly":[187],"overrepresented":[188],"among":[189],"presenting":[191],"significantly":[197],"improved":[198],"study.":[208],"results":[210],"further":[211],"suggest":[212],"should":[216],"be":[217],"included":[218],"symptom":[222],"checklist.":[223]},"counts_by_year":[{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}