{"id":"https://openalex.org/W2032062012","doi":"https://doi.org/10.1097/shk.0b013e3182454acf","title":"Delta Neutrophil Index: A Promising Diagnostic and Prognostic Marker for Sepsis","display_name":"Delta Neutrophil Index: A Promising Diagnostic and Prognostic Marker for Sepsis","publication_year":2012,"publication_date":"2012-01-17","ids":{"openalex":"https://openalex.org/W2032062012","doi":"https://doi.org/10.1097/shk.0b013e3182454acf","mag":"2032062012","pmid":"https://pubmed.ncbi.nlm.nih.gov/22258230"},"language":"en","primary_location":{"id":"doi:10.1097/shk.0b013e3182454acf","doi":"https://doi.org/10.1097/shk.0b013e3182454acf","is_oa":false,"landing_page_url":"https://doi.org/10.1097/shk.0b013e3182454acf","pdf_url":null,"source":{"id":"https://openalex.org/S174819509","display_name":"Shock","issn_l":"1073-2322","issn":["1073-2322","1540-0514"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Shock","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2032062012"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://ir.ymlib.yonsei.ac.kr/handle/22282913/91847","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028038912","display_name":"Yoonmi Seok","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Yoonmi Seok","raw_affiliation_strings":["Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea","Dept. of Laboratory Medicine, Yonsei Univ, College of Medicine. Seoul. Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]},{"raw_affiliation_string":"Dept. of Laboratory Medicine, Yonsei Univ, College of Medicine. Seoul. Korea","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055315261","display_name":"Jong Rak Choi","orcid":"https://orcid.org/0000-0002-0608-2989","observed_orcids":["https://orcid.org/0000-0002-0608-2989"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Jong Rak Choi","raw_affiliation_strings":["Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul","Yonsei university"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]},{"raw_affiliation_string":"Yonsei university","institution_ids":["https://openalex.org/I193775966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100665646","display_name":"Juwon Kim","orcid":"https://orcid.org/0000-0003-2010-4491","observed_orcids":["https://orcid.org/0000-0003-2010-4491"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Juwon Kim","raw_affiliation_strings":["Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul","Yonsei university"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]},{"raw_affiliation_string":"Yonsei university","institution_ids":["https://openalex.org/I193775966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101911030","display_name":"Young Keun Kim","orcid":"https://orcid.org/0000-0002-2120-6265","observed_orcids":["https://orcid.org/0000-0002-2120-6265","https://orcid.org/0000-0001-6262-372X"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Young Keun Kim","raw_affiliation_strings":["Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju","Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju; and","Internal Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju","institution_ids":["https://openalex.org/I193775966"]},{"raw_affiliation_string":"Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju; and","institution_ids":["https://openalex.org/I193775966"]},{"raw_affiliation_string":"Internal Medicine","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100702743","display_name":"Jong\u2010Wook Lee","orcid":"https://orcid.org/0000-0002-3660-4370","observed_orcids":["https://orcid.org/0000-0002-3660-4370"]},"institutions":[{"id":"https://openalex.org/I4405260642","display_name":"Chungju Medical Center","ror":"https://ror.org/042vhbr87","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I4405260642"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jongwook Lee","raw_affiliation_strings":["Department of Laboratory Medicine, Chungju Medical Center, Chungju-Si, Chungbuk-Do, Korea","Chungju Medical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Chungju Medical Center, Chungju-Si, Chungbuk-Do, Korea","institution_ids":["https://openalex.org/I4405260642"]},{"raw_affiliation_string":"Chungju Medical Center","institution_ids":["https://openalex.org/I4405260642"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076368797","display_name":"Jaewoo Song","orcid":"https://orcid.org/0000-0002-1877-5731","observed_orcids":["https://orcid.org/0000-0002-1877-5731"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Jaewoo Song","raw_affiliation_strings":["Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul","Yonsei university"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]},{"raw_affiliation_string":"Yonsei university","institution_ids":["https://openalex.org/I193775966"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109253672","display_name":"Sue Jeong Kim","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Sue Jeong Kim","raw_affiliation_strings":["Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul","Yonsei university"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]},{"raw_affiliation_string":"Yonsei university","institution_ids":["https://openalex.org/I193775966"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077384451","display_name":"Kyung\u2010A Lee","orcid":"https://orcid.org/0000-0001-5320-6705","observed_orcids":["https://orcid.org/0000-0001-5320-6705"]},"institutions":[{"id":"https://openalex.org/I193775966","display_name":"Yonsei University","ror":"https://ror.org/01wjejq96","country_code":"KR","type":"education","lineage":["https://openalex.org/I193775966"]},{"id":"https://openalex.org/I4210160791","display_name":"Yonsei University Health System","ror":"https://ror.org/04sze3c15","country_code":"KR","type":"healthcare","lineage":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Kyung-A Lee","raw_affiliation_strings":["Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul","Department of  Laboratory Medicine"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul","institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"]},{"raw_affiliation_string":"Department of  Laboratory Medicine","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5028038912","https://openalex.org/A5055315261","https://openalex.org/A5076368797","https://openalex.org/A5077384451","https://openalex.org/A5100665646","https://openalex.org/A5109253672"],"corresponding_institution_ids":["https://openalex.org/I193775966","https://openalex.org/I4210160791"],"apc_list":null,"apc_paid":null,"fwci":7.1115,"has_fulltext":false,"cited_by_count":129,"citation_normalized_percentile":{"value":0.97164716,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"37","issue":"3","first_page":"242","last_page":"246"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10218","display_name":"Sepsis Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14165","display_name":"Inflammation biomarkers and pathways","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11961","display_name":"Neonatal and Maternal Infections","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/delta-neutrophil-index","display_name":"delta neutrophil index","score":0.9990000128746033},{"id":"https://openalex.org/keywords/sepsis","display_name":"sepsis","score":0.9869999885559082},{"id":"https://openalex.org/keywords/severe-sepsis","display_name":"severe sepsis","score":0.984000027179718},{"id":"https://openalex.org/keywords/systemic-inflammatory-response-syndrome","display_name":"systemic inflammatory response syndrome","score":0.984000027179718},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.8889999985694885},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7860000133514404},{"id":"https://openalex.org/keywords/28-day-mortality","display_name":"28-day mortality","score":0.9739999771118164},{"id":"https://openalex.org/keywords/early-diagnosis","display_name":"early diagnosis","score":0.5609999895095825},{"id":"https://openalex.org/keywords/immature-granulocytes","display_name":"immature granulocytes","score":0.6850000023841858},{"id":"https://openalex.org/keywords/complete-blood-count","display_name":"complete blood count","score":0.8029999732971191}],"concepts":[{"id":"https://openalex.org/C2778384902","wikidata":"https://www.wikidata.org/wiki/Q183134","display_name":"Sepsis","level":2,"score":0.8991700410842896},{"id":"https://openalex.org/C119060515","wikidata":"https://www.wikidata.org/wiki/Q1916617","display_name":"Interquartile range","level":2,"score":0.8854806423187256},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.754707932472229},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.6032904386520386},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.569300651550293},{"id":"https://openalex.org/C2781195455","wikidata":"https://www.wikidata.org/wiki/Q422766","display_name":"C-reactive protein","level":3,"score":0.5456531643867493},{"id":"https://openalex.org/C2781090800","wikidata":"https://www.wikidata.org/wiki/Q776030","display_name":"Systemic inflammatory response syndrome","level":3,"score":0.4744078814983368},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.42229408025741577},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3925180733203888},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.21333089470863342}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002097","descriptor_name":"C-Reactive Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009195","descriptor_name":"Peroxidase","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":true},{"descriptor_ui":"D009504","descriptor_name":"Neutrophils","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018746","descriptor_name":"Systemic Inflammatory Response Syndrome","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D018746","descriptor_name":"Systemic Inflammatory Response Syndrome","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D018805","descriptor_name":"Sepsis","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1097/shk.0b013e3182454acf","doi":"https://doi.org/10.1097/shk.0b013e3182454acf","is_oa":false,"landing_page_url":"https://doi.org/10.1097/shk.0b013e3182454acf","pdf_url":null,"source":{"id":"https://openalex.org/S174819509","display_name":"Shock","issn_l":"1073-2322","issn":["1073-2322","1540-0514"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Shock","raw_type":"journal-article"},{"id":"pmid:22258230","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22258230","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Shock (Augusta, Ga.)","raw_type":"Journal Article"},{"id":"pmh:oai:ir.ymlib.yonsei.ac.kr:22282913/91847","doi":null,"is_oa":true,"landing_page_url":"https://ir.ymlib.yonsei.ac.kr/handle/22282913/91847","pdf_url":null,"source":{"id":"https://openalex.org/S4306400691","display_name":"YUHSpace (Yonsei University Medical Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193775966","host_organization_name":"Yonsei University","host_organization_lineage":["https://openalex.org/I193775966"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"}],"best_oa_location":{"id":"pmh:oai:ir.ymlib.yonsei.ac.kr:22282913/91847","doi":null,"is_oa":true,"landing_page_url":"https://ir.ymlib.yonsei.ac.kr/handle/22282913/91847","pdf_url":null,"source":{"id":"https://openalex.org/S4306400691","display_name":"YUHSpace (Yonsei University Medical Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I193775966","host_organization_name":"Yonsei University","host_organization_lineage":["https://openalex.org/I193775966"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":15,"referenced_works":["https://openalex.org/W1966076267","https://openalex.org/W1995232616","https://openalex.org/W2014802742","https://openalex.org/W2020270973","https://openalex.org/W2056735404","https://openalex.org/W2063941949","https://openalex.org/W2109417222","https://openalex.org/W2118470503","https://openalex.org/W2132408521","https://openalex.org/W2137615559","https://openalex.org/W2138808269","https://openalex.org/W2150258149","https://openalex.org/W2152955526","https://openalex.org/W2166162509","https://openalex.org/W2599527603"],"related_works":["https://openalex.org/W1993811022","https://openalex.org/W3197367824","https://openalex.org/W2031417602","https://openalex.org/W2914676667","https://openalex.org/W3184900448","https://openalex.org/W2404990944","https://openalex.org/W2739995351","https://openalex.org/W4387065486","https://openalex.org/W2081056256"],"abstract_inverted_index":{"Delta":[0,86,186,231],"neutrophil":[1,87,187,232],"index":[2,88,188,233],"(DN)":[3],"is":[4,23,254],"the":[5,27,34,47,94,97,104,124,130,139,146,156,198],"immature":[6],"granulocyte":[7],"fraction":[8,28],"provided":[9],"by":[10,25,226],"a":[11,167,237,257],"blood":[12,99,260],"cell":[13],"analyzer":[14],"(ADVIA":[15],"2120;":[16],"Siemens":[17],"Healthcare":[18],"Diagnostics,":[19],"Deerfield,":[20],"Ill),":[21],"which":[22],"determined":[24],"subtracting":[26],"of":[29,36,41,49,57,63,96,116,170,248],"mature":[30],"polymorphonuclear":[31],"leukocytes":[32],"from":[33],"sum":[35],"myeloperoxidase-reactive":[37],"cells.":[38],"The":[39,158,175],"purpose":[40],"this":[42],"study":[43],"was":[44,112,166,184,189,212],"to":[45,214],"define":[46],"role":[48],"DN":[50,117,165,180],"in":[51,123,129,138,145,192,197,222,256],"differential":[52],"diagnosis":[53,244],"and":[54,82,89,106,142,211,239,245],"prognosis":[55],"prediction":[56],"patients":[58,65,223,249],"with":[59,70,76,79,110,224,250],"sepsis.":[60],"Hospital":[61],"records":[62],"273":[64],"were":[66,101,118,152],"retrospectively":[67],"collected:":[68],"47":[69],"systemic":[71,131],"inflammatory":[72,132],"response":[73,133],"syndrome,":[74],"78":[75],"sepsis,":[77,81,251],"51":[78],"severe":[80,147],"97":[83],"control":[84,125],"subjects.":[85],"C-reactive":[90,173],"protein":[91],"data":[92],"on":[93],"day":[95],"first":[98],"culture":[100],"compared":[102],"among":[103,155],"groups,":[105],"28-day":[107,220],"mortality":[108,221],"associated":[109],"sepsis":[111,140,148,171,183,225],"assessed.":[113],"Median":[114],"values":[115],"0.0%":[119],"(interquartile":[120],"range,":[121],"0.0%-0.0%)":[122],"group,":[126,135,141],"0.8%":[127],"(0.0%-1.7%)":[128],"syndrome":[134],"3.4%":[136],"(1.5%-5.3%)":[137],"18.6%":[143],"(9.3%-24.7%)":[144],"group.":[149],"Furthermore,":[150],"there":[151],"significant":[153],"differences":[154],"groups.":[157],"receiver":[159],"operating":[160],"characteristic":[161],"curves":[162],"showed":[163],"that":[164],"better":[168],"predictor":[169,218],"than":[172,196],"protein.":[174],"best":[176],"cutoff":[177],"value":[178],"for":[179,181,219,242],"predicting":[182],"2.7%.":[185],"significantly":[190],"higher":[191],"those":[193],"who":[194],"died":[195],"survivors":[199],"(median":[200],"[interquartile":[201],"range],":[202],"11.5%":[203],"[3.5%-25.0%]":[204],"vs.":[205],"4.7%":[206],"[2.2%-10.6%],":[207],"P":[208],"=":[209],"0.008)":[210],"identified":[213],"be":[215],"an":[216],"independent":[217],"Cox":[227],"proportional":[228],"hazards":[229],"model.":[230],"may":[234],"serve":[235],"as":[236,252],"facile":[238],"useful":[240],"marker":[241],"early":[243],"prognostic":[246],"assessment":[247],"it":[253],"included":[255],"routine":[258],"complete":[259],"count.":[261]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":9},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":9},{"year":2018,"cited_by_count":9},{"year":2017,"cited_by_count":22},{"year":2016,"cited_by_count":10},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":10},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}