{"id":"https://openalex.org/W2032059141","doi":"https://doi.org/10.3171/jns.1998.89.3.0425","title":"Clinical outcome of gliosarcoma compared with glioblastoma multiforme: North Central Cancer Treatment Group results","display_name":"Clinical outcome of gliosarcoma compared with glioblastoma multiforme: North Central Cancer Treatment Group results","publication_year":1998,"publication_date":"1998-09-01","ids":{"openalex":"https://openalex.org/W2032059141","doi":"https://doi.org/10.3171/jns.1998.89.3.0425","mag":"2032059141","pmid":"https://pubmed.ncbi.nlm.nih.gov/9724117"},"language":"en","primary_location":{"id":"doi:10.3171/jns.1998.89.3.0425","doi":"https://doi.org/10.3171/jns.1998.89.3.0425","is_oa":false,"landing_page_url":"https://doi.org/10.3171/jns.1998.89.3.0425","pdf_url":null,"source":{"id":"https://openalex.org/S1995308","display_name":"Journal of neurosurgery","issn_l":"0022-3085","issn":["0022-3085","1933-0693"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316861","host_organization_name":"American Association of Neurological Surgeons","host_organization_lineage":["https://openalex.org/P4310316861"],"host_organization_lineage_names":["American Association of Neurological Surgeons"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurosurgery","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017494786","display_name":"Evanthia Galanis","orcid":"https://orcid.org/0000-0001-8014-786X","observed_orcids":["https://orcid.org/0000-0001-8014-786X"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Evanthia Galanis","raw_affiliation_strings":["Department of Oncology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Oncology, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034104319","display_name":"Jan C. Buckner","orcid":"https://orcid.org/0000-0002-8688-266X","observed_orcids":["https://orcid.org/0000-0002-8688-266X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jan C. Buckner","raw_affiliation_strings":["Medical Oncology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Oncology","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039903226","display_name":"Robert P. Dinapoli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert P. Dinapoli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110883848","display_name":"Bernd Walter Scheithauer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Bernd W. Scheithauer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060720802","display_name":"Robert Brian Jenkins","orcid":"https://orcid.org/0000-0002-4049-694X","observed_orcids":["https://orcid.org/0000-0002-4049-694X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Robert B. Jenkins","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109143987","display_name":"Chiao Hua Wang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Chiao Hua Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111486405","display_name":"Judith Rich O'Fallon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Judith R. O'Fallon","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111538323","display_name":"Gist H. Farr","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gist Farr","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.8505,"has_fulltext":false,"cited_by_count":180,"citation_normalized_percentile":{"value":0.85855249,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"89","issue":"3","first_page":"425","last_page":"430"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gliosarcoma","display_name":"gliosarcoma","score":0.9890000224113464},{"id":"https://openalex.org/keywords/glioblastoma","display_name":"glioblastoma","score":1.0},{"id":"https://openalex.org/keywords/astrocytoma","display_name":"astrocytoma","score":0.6669999957084656},{"id":"https://openalex.org/keywords/disease-free-survival","display_name":"disease-free survival","score":0.6990000009536743},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.7879999876022339},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.7350000143051147},{"id":"https://openalex.org/keywords/nitrosourea-chemotherapy","display_name":"nitrosourea chemotherapy","score":0.6600000262260437},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.7720000147819519},{"id":"https://openalex.org/keywords/tumor-progression","display_name":"tumor progression","score":0.4569999873638153},{"id":"https://openalex.org/keywords/genetic-similarity","display_name":"genetic similarity","score":0.3919999897480011},{"id":"https://openalex.org/keywords/central-nervous-system-malignancies","display_name":"central nervous system malignancies","score":0.675000011920929},{"id":"https://openalex.org/keywords/cell-of-origin","display_name":"cell of origin","score":0.6159999966621399},{"id":"https://openalex.org/keywords/tumor-aggressiveness","display_name":"tumor aggressiveness","score":0.4129999876022339},{"id":"https://openalex.org/keywords/north-central-cancer-treatment-group","display_name":"North Central Cancer Treatment Group","score":0.5519999861717224},{"id":"https://openalex.org/keywords/extent-of-resection","display_name":"extent of resection","score":0.6060000061988831}],"concepts":[{"id":"https://openalex.org/C2777295375","wikidata":"https://www.wikidata.org/wiki/Q609503","display_name":"Gliosarcoma","level":3,"score":0.9821596145629883},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9105737209320068},{"id":"https://openalex.org/C2776194525","wikidata":"https://www.wikidata.org/wiki/Q282142","display_name":"Glioblastoma","level":2,"score":0.5164902210235596},{"id":"https://openalex.org/C2779434656","wikidata":"https://www.wikidata.org/wiki/Q415378","display_name":"Lomustine","level":5,"score":0.4915529191493988},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4838079810142517},{"id":"https://openalex.org/C2779399171","wikidata":"https://www.wikidata.org/wiki/Q1483951","display_name":"Malignancy","level":2,"score":0.4526297450065613},{"id":"https://openalex.org/C204243189","wikidata":"https://www.wikidata.org/wiki/Q1363085","display_name":"Randomization","level":3,"score":0.44340789318084717},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4421805739402771},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.43345701694488525},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4113200604915619},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.35185307264328003},{"id":"https://openalex.org/C2779429289","wikidata":"https://www.wikidata.org/wiki/Q408977","display_name":"Vincristine","level":4,"score":0.0969158411026001},{"id":"https://openalex.org/C2776755627","wikidata":"https://www.wikidata.org/wiki/Q408524","display_name":"Cyclophosphamide","level":3,"score":0.07493802905082703},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000367","descriptor_name":"Age Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000970","descriptor_name":"Antineoplastic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D001932","descriptor_name":"Brain Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005625","descriptor_name":"Frontal Lobe","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005625","descriptor_name":"Frontal Lobe","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005909","descriptor_name":"Glioblastoma","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009607","descriptor_name":"Nitrosourea Compounds","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D009778","descriptor_name":"Occipital Lobe","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009778","descriptor_name":"Occipital Lobe","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D010296","descriptor_name":"Parietal Lobe","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010296","descriptor_name":"Parietal Lobe","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013702","descriptor_name":"Temporal Lobe","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013702","descriptor_name":"Temporal Lobe","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D015173","descriptor_name":"Supratentorial Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D015173","descriptor_name":"Supratentorial Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":false},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017024","descriptor_name":"Chemotherapy, Adjuvant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018316","descriptor_name":"Gliosarcoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D018316","descriptor_name":"Gliosarcoma","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018572","descriptor_name":"Disease-Free Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018714","descriptor_name":"Radiotherapy, Adjuvant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019070","descriptor_name":"Cell Lineage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3171/jns.1998.89.3.0425","doi":"https://doi.org/10.3171/jns.1998.89.3.0425","is_oa":false,"landing_page_url":"https://doi.org/10.3171/jns.1998.89.3.0425","pdf_url":null,"source":{"id":"https://openalex.org/S1995308","display_name":"Journal of neurosurgery","issn_l":"0022-3085","issn":["0022-3085","1933-0693"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310316861","host_organization_name":"American Association of Neurological Surgeons","host_organization_lineage":["https://openalex.org/P4310316861"],"host_organization_lineage_names":["American Association of Neurological Surgeons"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurosurgery","raw_type":"journal-article"},{"id":"pmid:9724117","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9724117","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neurosurgery","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307856","display_name":"World Health Organization","ror":"https://ror.org/01f80g185"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W76009976","https://openalex.org/W1480878209","https://openalex.org/W1552547506","https://openalex.org/W1963574391","https://openalex.org/W1979300931","https://openalex.org/W1979395779","https://openalex.org/W1994810553","https://openalex.org/W2004454589","https://openalex.org/W2008760850","https://openalex.org/W2015660037","https://openalex.org/W2016986202","https://openalex.org/W2047587242","https://openalex.org/W2055901718","https://openalex.org/W2056987446","https://openalex.org/W2058604848","https://openalex.org/W2059670935","https://openalex.org/W2088925558","https://openalex.org/W2090822861","https://openalex.org/W2093729382","https://openalex.org/W2095298015","https://openalex.org/W2165696859","https://openalex.org/W2167152442","https://openalex.org/W2187668060","https://openalex.org/W2256352880","https://openalex.org/W2323523318","https://openalex.org/W2513915884","https://openalex.org/W3041047318"],"related_works":["https://openalex.org/W2024590855","https://openalex.org/W1994810553","https://openalex.org/W2590666910","https://openalex.org/W2200757787","https://openalex.org/W7133099604","https://openalex.org/W2188679766","https://openalex.org/W18510600","https://openalex.org/W6893023166","https://openalex.org/W7099857738","https://openalex.org/W2995896640"],"abstract_inverted_index":{"OBJECT:":[0],"Gliosarcoma,":[1],"a":[2,59,88,131,192],"rare":[3],"malignancy":[4],"of":[5,11,26,31,37,62,73,84,90,99,120,134,186,195,213,259,292,347],"the":[6,70,114,183,234,239,256,278,302,315,329],"central":[7],"nervous":[8],"system,":[9],"consists":[10],"gliomatous":[12,303],"and":[13,23,50,109,123,127,164,191,215,225,233,245,252,269,272,274,284,304,322,327,341],"sarcomatous":[14,305],"elements.":[15],"There":[16],"are":[17],"conflicting":[18],"reports":[19],"regarding":[20],"its":[21],"aggressiveness":[22],"cell":[24],"line":[25],"origin":[27],"compared":[28,181,249],"with":[29,56,58,64,69,75,130,171,182,189,198,241,250,261,325],"those":[30],"glioblastoma":[32],"multiforme":[33],"(GBM).":[34],"The":[35,78,140,150,168,228,308],"goal":[36],"this":[38,112,312],"study":[39,313],"was":[40,144],"to":[41,231],"compare":[42],"clinicopathological":[43],"features":[44],"such":[45],"as":[46,66,68,248],"disease-free":[47],"survival":[48,52,236],"time":[49,53,230],"actual":[51],"in":[54,156,159,162,166,219,277,301,311,338],"patients":[55,63,74,170,188,197,240,260],"gliosarcoma":[57,85,115,242,293,318],"matched":[60,200],"group":[61,72,116,185,194,258,280],"GBM":[65,190,199,262,326],"well":[67],"entire":[71,184,257],"GBM.":[76],"METHODS:":[77],"authors":[79,295],"report":[80],"on":[81],"18":[82,169,196],"cases":[83,95],"derived":[86],"from":[87],"series":[89,113],"748":[91],"Grade":[92,174],"4":[93,175],"astrocytoma":[94],"that":[96,317,328],"were":[97,180,243],"part":[98],"four":[100],"consecutive":[101],"randomized":[102],"Phase":[103],"III":[104],"trials":[105],"conducted":[106],"between":[107],"1979":[108],"1996.":[110],"In":[111,287],"represented":[117],"only":[118],"2.4%":[119],"all":[121,152,173,220],"GBMs":[122],"included":[124,154],"11":[125],"men":[126],"seven":[128],"women":[129],"median":[132,141,229,235],"age":[133],"61.5":[135],"years":[136],"(range":[137,147],"31-81":[138],"years).":[139],"tumor":[142],"size":[143],"5":[145],"cm":[146],"2-8":[148],"cm).":[149],"locations,":[151],"supratentorial,":[153],"temporal":[155],"44%,":[157],"parietal":[158],"28%,":[160],"frontal":[161],"17%,":[163],"occipital":[165],"11%.":[167],"gliosarcomas,":[172],"(World":[176],"Health":[177],"Organization":[178],"classification),":[179],"730":[187],"control":[193,279],"for":[201,238,255,335,343],"known":[202],"prognostic":[203],"factors":[204],"including":[205],"patient":[206,336],"age,":[207],"randomization":[208],"date,":[209],"performance":[210],"status,":[211],"extent":[212],"resection,":[214],"protocol":[216],"number.":[217],"Patients":[218],"treatment":[221,342],"groups":[222],"received":[223],"radiation":[224],"nitrosourea-based":[226],"chemotherapy.":[227],"progression":[232],"times":[237],"28.0":[244],"35.1":[246],"weeks":[247,254,276],"24.7":[251],"41.6":[253],"(log":[263],"rank":[264],"test,":[265],"p":[266],"=":[267,282],"0.94":[268],"0.27,":[270],"respectively)":[271],"16.7":[273],"34.4":[275],"(p":[281],"0.20":[283],"0.84,":[285],"respectively).":[286],"previous":[288],"molecular":[289],"cytogenetic":[290],"analyses":[291],"these":[294,344],"have":[296],"shown":[297],"similar":[298],"genetic":[299,323],"changes":[300],"components.":[306],"CONCLUSIONS:":[307],"data":[309],"obtained":[310],"support":[314],"conclusion":[316],"shares":[319],"significant":[320],"clinical":[321],"similarities":[324],"same":[330],"principles":[331],"should":[332],"be":[333],"applied":[334],"enrollment":[337],"research":[339],"protocols":[340],"two":[345],"kinds":[346],"tumor.":[348]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":11},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":11},{"year":2016,"cited_by_count":13},{"year":2015,"cited_by_count":11},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":11}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}