{"id":"https://openalex.org/W2032058507","doi":"https://doi.org/10.3109/02713688808995749","title":"Pattern reversal electroretinogram (PRERG) abnormalities in ocular hypertension: correlation with glaucoma risk factors","display_name":"Pattern reversal electroretinogram (PRERG) abnormalities in ocular hypertension: correlation with glaucoma risk factors","publication_year":1988,"publication_date":"1988-01-01","ids":{"openalex":"https://openalex.org/W2032058507","doi":"https://doi.org/10.3109/02713688808995749","mag":"2032058507","pmid":"https://pubmed.ncbi.nlm.nih.gov/3371068"},"language":"en","primary_location":{"id":"doi:10.3109/02713688808995749","doi":"https://doi.org/10.3109/02713688808995749","is_oa":false,"landing_page_url":"https://doi.org/10.3109/02713688808995749","pdf_url":null,"source":{"id":"https://openalex.org/S74941265","display_name":"Current Eye Research","issn_l":"0271-3683","issn":["0271-3683","1460-2202"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Eye Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109201552","display_name":"Gary L. Trick","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gary L. Trick","raw_affiliation_strings":["Department of Ophthalmology, Washington University School of Medicine, St. Louis, MO 63110"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Washington University School of Medicine, St. Louis, MO 63110","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015447680","display_name":"Michelle Bickler\u2010Bluth","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michelle Bickler-Bluth","raw_affiliation_strings":["Department of Ophthalmology, Washington University School of Medicine, 660 South Euclid Avenue, Box 8096, St Louis, MO, 63110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Washington University School of Medicine, 660 South Euclid Avenue, Box 8096, St Louis, MO, 63110, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042727383","display_name":"Dorothy G. Cooper","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dorothy G. Cooper","raw_affiliation_strings":["Department of Ophthalmology, Washington University School of Medicine, 660 South Euclid Avenue, Box 8096, St Louis, MO, 63110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Washington University School of Medicine, 660 South Euclid Avenue, Box 8096, St Louis, MO, 63110, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048202800","display_name":"Allan E. Kolker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Allan E. Kolker","raw_affiliation_strings":["Department of Ophthalmology, Washington University School of Medicine, 660 South Euclid Avenue, Box 8096, St Louis, MO, 63110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Washington University School of Medicine, 660 South Euclid Avenue, Box 8096, St Louis, MO, 63110, USA","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111973476","display_name":"\u0420\u043e\u043d\u0438\u0442 \u041d\u0435\u0448\u0435\u0440","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ronit Nesher","raw_affiliation_strings":["Department of Ophthalmology, Washington University School of Medicine, 660 South Euclid Avenue, Box 8096, St Louis, MO, 63110, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Ophthalmology, Washington University School of Medicine, 660 South Euclid Avenue, Box 8096, St Louis, MO, 63110, USA","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":null,"apc_paid":null,"fwci":2.6283,"has_fulltext":false,"cited_by_count":32,"citation_normalized_percentile":{"value":0.88767229,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"7","issue":"2","first_page":"201","last_page":"206"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10250","display_name":"Glaucoma and retinal disorders","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13467","display_name":"Drug-Induced Ocular Toxicity","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11438","display_name":"Retinal Imaging and Analysis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ocular-hypertension","display_name":"ocular hypertension","score":0.996999979019165},{"id":"https://openalex.org/keywords/primary-open-angle-glaucoma","display_name":"primary open-angle glaucoma","score":0.9940000176429749},{"id":"https://openalex.org/keywords/glaucoma-risk-factors","display_name":"glaucoma risk factors","score":0.8199999928474426},{"id":"https://openalex.org/keywords/diastolic-blood-pressure","display_name":"diastolic blood pressure","score":0.8960000276565552},{"id":"https://openalex.org/keywords/retinal-ganglion-cells","display_name":"retinal ganglion cells","score":0.7300000190734863},{"id":"https://openalex.org/keywords/optic-nerve","display_name":"optic nerve","score":0.7390000224113464},{"id":"https://openalex.org/keywords/glaucoma-screening","display_name":"glaucoma screening","score":0.5989999771118164},{"id":"https://openalex.org/keywords/visual-field-defects","display_name":"visual field defects","score":0.4740000069141388}],"concepts":[{"id":"https://openalex.org/C118487528","wikidata":"https://www.wikidata.org/wiki/Q161437","display_name":"Ophthalmology","level":1,"score":0.7817637324333191},{"id":"https://openalex.org/C2776521421","wikidata":"https://www.wikidata.org/wiki/Q9294051","display_name":"Ocular hypertension","level":3,"score":0.7807449102401733},{"id":"https://openalex.org/C2778527774","wikidata":"https://www.wikidata.org/wiki/Q159701","display_name":"Glaucoma","level":2,"score":0.7526987791061401},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6780151128768921},{"id":"https://openalex.org/C117220453","wikidata":"https://www.wikidata.org/wiki/Q5172842","display_name":"Correlation","level":2,"score":0.5260308384895325},{"id":"https://openalex.org/C119767625","wikidata":"https://www.wikidata.org/wiki/Q618211","display_name":"Optometry","level":1,"score":0.3687506318092346},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000704","descriptor_name":"Analysis of Variance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004596","descriptor_name":"Electroretinography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D005901","descriptor_name":"Glaucoma","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009798","descriptor_name":"Ocular Hypertension","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D009798","descriptor_name":"Ocular Hypertension","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D012016","descriptor_name":"Reference Values","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3109/02713688808995749","doi":"https://doi.org/10.3109/02713688808995749","is_oa":false,"landing_page_url":"https://doi.org/10.3109/02713688808995749","pdf_url":null,"source":{"id":"https://openalex.org/S74941265","display_name":"Current Eye Research","issn_l":"0271-3683","issn":["0271-3683","1460-2202"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320547","host_organization_name":"Taylor & Francis","host_organization_lineage":["https://openalex.org/P4310320547","https://openalex.org/P4310320449"],"host_organization_lineage_names":["Taylor & Francis","Informa"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Eye Research","raw_type":"journal-article"},{"id":"pmid:3371068","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3371068","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current eye research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G4960393559","display_name":null,"funder_award_id":"EY06046","funder_id":"https://openalex.org/F4320337350","funder_display_name":"National Eye Institute"}],"funders":[{"id":"https://openalex.org/F4320337350","display_name":"National Eye Institute","ror":"https://ror.org/03wkg3b53"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W123146709","https://openalex.org/W137829501","https://openalex.org/W154679875","https://openalex.org/W1821793674","https://openalex.org/W1880340933","https://openalex.org/W1964458657","https://openalex.org/W1970428486","https://openalex.org/W1980296697","https://openalex.org/W1987641085","https://openalex.org/W1998417817","https://openalex.org/W2005717228","https://openalex.org/W2014018024","https://openalex.org/W2031895914","https://openalex.org/W2031918849","https://openalex.org/W2056009434","https://openalex.org/W2082567274","https://openalex.org/W2087462702"],"related_works":["https://openalex.org/W2068748784","https://openalex.org/W2016061139","https://openalex.org/W4321070430","https://openalex.org/W154679875","https://openalex.org/W2000742990","https://openalex.org/W2022741940","https://openalex.org/W4360615581","https://openalex.org/W2917427348","https://openalex.org/W2435980392","https://openalex.org/W2962393604"],"abstract_inverted_index":{"The":[0,37,198],"indices":[1,210],"employed":[2],"commonly":[3,207],"for":[4,142,216],"the":[5,51,66,143,160,206],"diagnosis":[6],"of":[7,50,117,148,200],"glaucoma":[8,27],"(tonometry,":[9],"ophthalmoscopy":[10],"and":[11,62,69,86,123,146,176,187,205],"perimetry)":[12],"do":[13],"not":[14],"always":[15],"identify":[16],"which":[17,222],"patients":[18,81,119,145,150,224],"with":[19,92,120,171,179],"ocular":[20,121],"hypertension":[21,122],"(OHT)":[22],"will":[23,225],"develop":[24,226],"primary":[25],"open-angle":[26],"(POAG)":[28],"before":[29],"irreversible":[30],"visual":[31,127],"field":[32],"loss":[33],"is":[34,43],"manifest":[35],"(1).":[36],"human":[38],"pattern":[39],"reversal":[40],"electroretinogram":[41],"(PRERG)":[42],"a":[44,213],"bioelectric":[45],"response":[46],"reflecting":[47],"neural":[48],"activity":[49],"proximal":[52],"retina.":[53],"PRERG":[54,83,88,98,138,152,163,185,203],"amplitude":[55,84,139,164,186,204],"reductions":[56,85],"have":[57],"been":[58],"observed":[59],"in":[60,137,220],"POAG":[61],"other":[63],"diseases":[64],"affecting":[65],"optic":[67],"nerve":[68],"retinal":[70],"ganglion":[71],"cells.":[72],"This":[73],"study":[74],"was":[75,140,165,196],"designed":[76],"to":[77,167],"determine":[78],"whether":[79,87],"OHT":[80,144,223],"exhibit":[82],"results":[89],"are":[90],"correlated":[91,170,178],"routinely":[93],"evaluated":[94],"clinical":[95,209],"parameters.":[96],"Steady-state":[97],"(16":[99],"rps)":[100],"were":[101],"elicited":[102],"by":[103],"high":[104],"contrast":[105],"(76%),":[106],"phase":[107],"alternating":[108],"checkerboard":[109],"patterns":[110],"(15-20":[111],"min":[112],"checks)":[113],"from":[114],"one":[115],"eye":[116],"130":[118],"47":[124],"age":[125],"matched":[126],"normals":[128],"(AMVNs).":[129],"A":[130],"significant":[131],"(p":[132],"less":[133],"than":[134,155],"0.05)":[135],"reduction":[136],"noted":[141],"11.5%":[147],"those":[149],"exhibited":[151],"amplitudes":[153],"more":[154],"2.0":[156],"standard":[157],"deviations":[158],"below":[159],"AMVN":[161],"mean.":[162],"found":[166],"be":[168],"positively":[169],"diastolic":[172],"blood":[173,194],"pressure":[174,195],"(DBP)":[175],"negatively":[177],"age,":[180],"but":[181],"no":[182],"correlation":[183,201],"between":[184,202],"either":[188],"IOP,":[189],"C/D":[190],"ratio,":[191],"or":[192],"systolic":[193],"evident.":[197],"lack":[199],"used":[208],"may":[211],"suggest":[212],"complementary":[214],"role":[215],"this":[217],"neurophysiologic":[218],"test":[219],"determining":[221],"glaucoma.":[227]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}