{"id":"https://openalex.org/W2031443364","doi":"https://doi.org/10.1007/bf01800243","title":"Selective killing of cells with oxidative defects in galactose medium: A screening test for affected patient fibroblasts","display_name":"Selective killing of cells with oxidative defects in galactose medium: A screening test for affected patient fibroblasts","publication_year":1992,"publication_date":"1992-11-01","ids":{"openalex":"https://openalex.org/W2031443364","doi":"https://doi.org/10.1007/bf01800243","mag":"2031443364","pmid":"https://pubmed.ncbi.nlm.nih.gov/1293397"},"language":"en","primary_location":{"id":"doi:10.1007/bf01800243","doi":"https://doi.org/10.1007/bf01800243","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf01800243","pdf_url":null,"source":{"id":"https://openalex.org/S186577254","display_name":"Journal of Inherited Metabolic Disease","issn_l":"0141-8955","issn":["0141-8955","1573-2665"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Inherited Metabolic Disease","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091389858","display_name":"Roumyana Petrova-Benedict","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I2801317318","display_name":"Hospital for Sick Children","ror":"https://ror.org/057q4rt57","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801317318"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"R. Petrova\u2010Benedict","raw_affiliation_strings":["Department of Genetics, The Research Institute, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8 Canada","Departments of Biochemistry and Paediatrics, University of Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, The Research Institute, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8 Canada","institution_ids":["https://openalex.org/I2801317318"]},{"raw_affiliation_string":"Departments of Biochemistry and Paediatrics, University of Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078700478","display_name":"J. Raymond Buncic","orcid":"https://orcid.org/0000-0002-4122-8496","observed_orcids":["https://orcid.org/0000-0002-4122-8496"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I2801317318","display_name":"Hospital for Sick Children","ror":"https://ror.org/057q4rt57","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801317318"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"J. R. Buncic","raw_affiliation_strings":["Department of Genetics, The Research Institute, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8 Canada","Departments of Biochemistry and Paediatrics, University of Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, The Research Institute, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8 Canada","institution_ids":["https://openalex.org/I2801317318"]},{"raw_affiliation_string":"Departments of Biochemistry and Paediatrics, University of Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085274471","display_name":"Douglas C. Wallace","orcid":"https://orcid.org/0000-0002-7480-8278","observed_orcids":["https://orcid.org/0000-0002-7480-8278"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. C. Wallace","raw_affiliation_strings":["Department of Biochemistry, Emory University, Atlanta, Georgia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, Emory University, Atlanta, Georgia, USA","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111871872","display_name":"B. H. Robinson","orcid":"https://orcid.org/0000-0002-3454-1724","observed_orcids":["https://orcid.org/0000-0002-3454-1724"]},"institutions":[{"id":"https://openalex.org/I185261750","display_name":"University of Toronto","ror":"https://ror.org/03dbr7087","country_code":"CA","type":"education","lineage":["https://openalex.org/I185261750"]},{"id":"https://openalex.org/I2801317318","display_name":"Hospital for Sick Children","ror":"https://ror.org/057q4rt57","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801317318"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"B. H. Robinson","raw_affiliation_strings":["Department of Genetics, The Research Institute, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8 Canada","Departments of Biochemistry and Paediatrics, University of Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics, The Research Institute, The Hospital for Sick Children, 555 University Avenue, Toronto, Ontario, M5G 1X8 Canada","institution_ids":["https://openalex.org/I2801317318"]},{"raw_affiliation_string":"Departments of Biochemistry and Paediatrics, University of Toronto, Canada","institution_ids":["https://openalex.org/I185261750"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3470,"currency":"USD","value_usd":3470},"apc_paid":null,"fwci":0.2519,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.46099291,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"15","issue":"6","first_page":"943","last_page":"944"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11027","display_name":"Metabolism and Genetic Disorders","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10945","display_name":"Lysosomal Storage Disorders Research","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12604","display_name":"Glycogen Storage Diseases and Myoclonus","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/galactosemia","display_name":"galactosemia","score":0.7490000128746033},{"id":"https://openalex.org/keywords/galactose-metabolism","display_name":"galactose metabolism","score":0.48899999260902405},{"id":"https://openalex.org/keywords/selective-cell-killing","display_name":"selective cell killing","score":0.6420000195503235},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.859000027179718},{"id":"https://openalex.org/keywords/galactose-medium","display_name":"galactose medium","score":0.6850000023841858}],"concepts":[{"id":"https://openalex.org/C3017960651","wikidata":"https://www.wikidata.org/wiki/Q92783654","display_name":"Sick child","level":2,"score":0.6996132731437683},{"id":"https://openalex.org/C3017595490","wikidata":"https://www.wikidata.org/wiki/Q17006263","display_name":"University hospital","level":2,"score":0.5431910157203674},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4860873520374298},{"id":"https://openalex.org/C2992786221","wikidata":"https://www.wikidata.org/wiki/Q849994","display_name":"Clinical biochemistry","level":2,"score":0.47299060225486755},{"id":"https://openalex.org/C512399662","wikidata":"https://www.wikidata.org/wiki/Q3505712","display_name":"Family medicine","level":1,"score":0.43246781826019287},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.33683598041534424},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.30805709958076477},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.16010552644729614},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D003470","descriptor_name":"Culture Media","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D005347","descriptor_name":"Fibroblasts","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005690","descriptor_name":"Galactose","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008661","descriptor_name":"Metabolism, Inborn Errors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008661","descriptor_name":"Metabolism, Inborn Errors","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/bf01800243","doi":"https://doi.org/10.1007/bf01800243","is_oa":false,"landing_page_url":"https://doi.org/10.1007/bf01800243","pdf_url":null,"source":{"id":"https://openalex.org/S186577254","display_name":"Journal of Inherited Metabolic Disease","issn_l":"0141-8955","issn":["0141-8955","1573-2665"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Inherited Metabolic Disease","raw_type":"journal-article"},{"id":"pmid:1293397","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1293397","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of inherited metabolic disease","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":8,"referenced_works":["https://openalex.org/W1979767736","https://openalex.org/W1989067988","https://openalex.org/W2010756313","https://openalex.org/W2045501902","https://openalex.org/W2045957635","https://openalex.org/W2063575568","https://openalex.org/W2078939558","https://openalex.org/W2153960414"],"related_works":["https://openalex.org/W2046307510","https://openalex.org/W2435005293","https://openalex.org/W2051564370","https://openalex.org/W4384340451","https://openalex.org/W2303644995","https://openalex.org/W2429253783","https://openalex.org/W2328694970","https://openalex.org/W2919419574","https://openalex.org/W4391378232","https://openalex.org/W4389607132"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}