{"id":"https://openalex.org/W2031050860","doi":"https://doi.org/10.1118/1.1852793","title":"Effects of region-of-interest length on estimates of myocardial ultrasonic attenuation and backscatter","display_name":"Effects of region-of-interest length on estimates of myocardial ultrasonic attenuation and backscatter","publication_year":2005,"publication_date":"2005-01-21","ids":{"openalex":"https://openalex.org/W2031050860","doi":"https://doi.org/10.1118/1.1852793","mag":"2031050860","pmid":"https://pubmed.ncbi.nlm.nih.gov/15789588"},"language":"en","primary_location":{"id":"doi:10.1118/1.1852793","doi":"https://doi.org/10.1118/1.1852793","is_oa":false,"landing_page_url":"https://doi.org/10.1118/1.1852793","pdf_url":null,"source":{"id":"https://openalex.org/S95522064","display_name":"Medical Physics","issn_l":"0094-2405","issn":["0094-2405","1522-8541","2473-4209"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Physics","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059730641","display_name":"Steven L. Baldwin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Steven L. Baldwin","raw_affiliation_strings":["Washington University, St Louis, Missouri 63130, USA","Washington University, St. Louis, Missouri 63130"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington University, St Louis, Missouri 63130, USA","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Washington University, St. Louis, Missouri 63130","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101959673","display_name":"Mark R. Holland","orcid":"https://orcid.org/0000-0002-0565-8720","observed_orcids":["https://orcid.org/0000-0002-0565-8720"]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Mark R. Holland","raw_affiliation_strings":["Electronic mail: [email protected]","Electronic mail: mrh@wuphys.wustl.edu","Washington University, St. Louis, Missouri 63130"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Electronic mail: [email protected]","institution_ids":[]},{"raw_affiliation_string":"Electronic mail: mrh@wuphys.wustl.edu","institution_ids":["https://openalex.org/I204465549"]},{"raw_affiliation_string":"Washington University, St. Louis, Missouri 63130","institution_ids":["https://openalex.org/I204465549"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006765223","display_name":"David E. Sosnovik","orcid":"https://orcid.org/0000-0002-6486-7434","observed_orcids":["https://orcid.org/0000-0002-6486-7434"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210087915","display_name":"Massachusetts General Hospital","ror":"https://ror.org/002pd6e78","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210087915","https://openalex.org/I48633490"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David E. Sosnovik","raw_affiliation_strings":["Department of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210087915"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5111604222","display_name":"James Grier Miller","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I204465549","display_name":"Washington University in St. Louis","ror":"https://ror.org/01yc7t268","country_code":"US","type":"education","lineage":["https://openalex.org/I204465549"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James G. Miller","raw_affiliation_strings":["Washington University, St. Louis, Missouri 63130"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington University, St. Louis, Missouri 63130","institution_ids":["https://openalex.org/I204465549"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5101959673"],"corresponding_institution_ids":["https://openalex.org/I204465549"],"apc_list":{"value":3360,"currency":"USD","value_usd":3360},"apc_paid":null,"fwci":1.077,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.76406433,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"32","issue":"2","first_page":"418","last_page":"426"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10727","display_name":"Ultrasound Imaging and Elastography","score":0.9477999806404114,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10727","display_name":"Ultrasound Imaging and Elastography","score":0.9477999806404114,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.027799999341368675,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12015","display_name":"Photoacoustic and Ultrasonic Imaging","score":0.0038999998942017555,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/backscatter-coefficient","display_name":"backscattering coefficient","score":0.828000009059906},{"id":"https://openalex.org/keywords/myocardial-anisotropy","display_name":"myocardial anisotropy","score":0.8309999704360962},{"id":"https://openalex.org/keywords/tissue-characterization","display_name":"tissue characterization","score":0.5170000195503235},{"id":"https://openalex.org/keywords/external-references","display_name":"external references","score":0.453000009059906},{"id":"https://openalex.org/keywords/echocardiography","display_name":"echocardiography","score":0.7269999980926514},{"id":"https://openalex.org/keywords/sheep-heart","display_name":"sheep heart","score":0.5099999904632568}],"concepts":[{"id":"https://openalex.org/C19609008","wikidata":"https://www.wikidata.org/wiki/Q2138203","display_name":"Region of interest","level":2,"score":0.8341472744941711},{"id":"https://openalex.org/C30354325","wikidata":"https://www.wikidata.org/wiki/Q204667","display_name":"Backscatter (email)","level":3,"score":0.7761149406433105},{"id":"https://openalex.org/C184652730","wikidata":"https://www.wikidata.org/wiki/Q2357982","display_name":"Attenuation","level":2,"score":0.7657980918884277},{"id":"https://openalex.org/C2779751349","wikidata":"https://www.wikidata.org/wiki/Q1474480","display_name":"Scanner","level":2,"score":0.6823474168777466},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.5402095317840576},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.5185685753822327},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.496277391910553},{"id":"https://openalex.org/C21353171","wikidata":"https://www.wikidata.org/wiki/Q6522493","display_name":"Length measurement","level":2,"score":0.489732027053833},{"id":"https://openalex.org/C81288441","wikidata":"https://www.wikidata.org/wiki/Q20736125","display_name":"Ultrasonic sensor","level":2,"score":0.43936020135879517},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.3758429288864136},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.28333908319473267},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.25345301628112793},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.21530771255493164},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1846335530281067},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.17570915818214417},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.16132473945617676},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.13550296425819397},{"id":"https://openalex.org/C555944384","wikidata":"https://www.wikidata.org/wiki/Q249","display_name":"Wireless","level":2,"score":0.0},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004452","descriptor_name":"Echocardiography","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D004452","descriptor_name":"Echocardiography","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006321","descriptor_name":"Heart","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D007089","descriptor_name":"Image Enhancement","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008954","descriptor_name":"Models, Biological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012542","descriptor_name":"Scattering, Radiation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012756","descriptor_name":"Sheep","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014741","descriptor_name":"Video Recording","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019047","descriptor_name":"Phantoms, Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1118/1.1852793","doi":"https://doi.org/10.1118/1.1852793","is_oa":false,"landing_page_url":"https://doi.org/10.1118/1.1852793","pdf_url":null,"source":{"id":"https://openalex.org/S95522064","display_name":"Medical Physics","issn_l":"0094-2405","issn":["0094-2405","1522-8541","2473-4209"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical Physics","raw_type":"journal-article"},{"id":"pmid:15789588","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15789588","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical physics","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2927869494","display_name":"Anisotropy in Myocardial Ultrasound","funder_award_id":"R37HL040302","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":41,"referenced_works":["https://openalex.org/W1798861396","https://openalex.org/W1965728853","https://openalex.org/W1968114652","https://openalex.org/W1970497783","https://openalex.org/W1971791956","https://openalex.org/W1984721343","https://openalex.org/W1995149449","https://openalex.org/W1997749334","https://openalex.org/W2010209150","https://openalex.org/W2012126091","https://openalex.org/W2014516110","https://openalex.org/W2022120257","https://openalex.org/W2022164373","https://openalex.org/W2026586395","https://openalex.org/W2042688256","https://openalex.org/W2047897296","https://openalex.org/W2051078969","https://openalex.org/W2055497980","https://openalex.org/W2058662315","https://openalex.org/W2062006925","https://openalex.org/W2063196506","https://openalex.org/W2063812299","https://openalex.org/W2064934023","https://openalex.org/W2070200234","https://openalex.org/W2079914838","https://openalex.org/W2083290118","https://openalex.org/W2084069189","https://openalex.org/W2094959483","https://openalex.org/W2121225926","https://openalex.org/W2121610338","https://openalex.org/W2122872992","https://openalex.org/W2131437985","https://openalex.org/W2142929913","https://openalex.org/W2149096350","https://openalex.org/W2153797429","https://openalex.org/W2156310318","https://openalex.org/W2161271315","https://openalex.org/W2164164924","https://openalex.org/W2325408202","https://openalex.org/W2346425161","https://openalex.org/W2468027974"],"related_works":["https://openalex.org/W1998344040","https://openalex.org/W1972817987","https://openalex.org/W2089253855","https://openalex.org/W2130459123","https://openalex.org/W2010209150","https://openalex.org/W1978845911","https://openalex.org/W1821885756","https://openalex.org/W3007069940","https://openalex.org/W2012232737","https://openalex.org/W1029473274"],"abstract_inverted_index":{"Measurements":[0],"of":[1,11,27,35,48,59,116,131,138,157],"tissue":[2,67,148],"properties":[3,44,58,134,149],"using":[4,84],"an":[5,12],"image-based":[6],"technique":[7,37],"that":[8,143],"makes":[9],"use":[10],"external":[13],"reference":[14],"may":[15],"have":[16],"the":[17,33,49,56,60,93,114,117,132,139,144,171,185],"potential":[18],"for":[19,45,65,135,154,168,188],"practical":[20],"clinical":[21,89],"implementation":[22],"in":[23,92],"echocardiography.":[24],"The":[25],"objective":[26],"this":[28,36],"study":[29],"was":[30],"to":[31,38,54,112,122,146],"quantify":[32],"ability":[34,115,145],"distinguish":[39,147],"myocardial":[40],"attenuation":[41,158],"and":[42,104,159],"backscatter":[43,160],"specific":[46,136],"lengths":[47,137,173],"region-of-interest":[50],"(ROI).":[51],"We":[52],"chose":[53],"exploit":[55],"anisotropic":[57],"myocardium":[61],"as":[62,174,176],"a":[63,85,98],"model":[64],"distinguishing":[66],"with":[68,97,151,179],"different":[69],"acoustic":[70,133],"properties.":[71],"Excised":[72],"lateral":[73],"wall":[74],"segments":[75],"from":[76,125],"seven":[77],"healthy":[78],"adult":[79],"sheep":[80],"hearts":[81],"were":[82,110,166],"imaged":[83],"commercially":[86],"available":[87],"(Philips/ATL)":[88],"scanner":[90],"operating":[91,106],"fundamental":[94],"imaging":[95],"mode":[96],"linear":[99],"array":[100],"(L":[101],"7-4).":[102],"Statistical":[103],"receiver":[105],"characteristic":[107],"(ROC)":[108],"analyses":[109],"used":[111],"evaluate":[113],"video":[118],"signal":[119],"analysis":[120],"method":[121],"differentiate":[123],"midmyocardial":[124],"subendocardial":[126],"regions":[127],"based":[128],"on":[129],"measurements":[130,169],"ROI.":[140],"Results":[141],"demonstrate":[142],"increases":[150],"ROI":[152,172,190],"length":[153],"both":[155],"slope":[156],"coefficient":[161],"measurements.":[162],"Statistically":[163],"significant":[164],"differences":[165],"observed":[167],"utilizing":[170],"short":[175],"0.4":[177],"cm":[178],"corresponding":[180],"progressively":[181],"increasing":[182,189],"areas":[183],"under":[184],"ROC":[186],"curves":[187],"lengths.":[191],"[NIH":[192],"R37":[193],"HL40302]":[194]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-01T11:40:01.658920","created_date":"2016-06-24T00:00:00"}