{"id":"https://openalex.org/W2030188129","doi":"https://doi.org/10.1016/j.bbrc.2008.09.040","title":"RNA interference mediated inhibition of Chikungunya virus replication in mammalian cells","display_name":"RNA interference mediated inhibition of Chikungunya virus replication in mammalian cells","publication_year":2008,"publication_date":"2008-09-20","ids":{"openalex":"https://openalex.org/W2030188129","doi":"https://doi.org/10.1016/j.bbrc.2008.09.040","mag":"2030188129","pmid":"https://pubmed.ncbi.nlm.nih.gov/18805396"},"language":"en","primary_location":{"id":"doi:10.1016/j.bbrc.2008.09.040","doi":"https://doi.org/10.1016/j.bbrc.2008.09.040","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bbrc.2008.09.040","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102757054","display_name":"Paban Kumar Dash","orcid":"https://orcid.org/0000-0003-4322-2044","observed_orcids":["https://orcid.org/0000-0003-4322-2044"]},"institutions":[{"id":"https://openalex.org/I2800900741","display_name":"Defence Research and Development Establishment","ror":"https://ror.org/04sm60f26","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1340206300","https://openalex.org/I2799351866","https://openalex.org/I2800900741","https://openalex.org/I4210150591"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Paban Kumar Dash","raw_affiliation_strings":["Division of Virology, Defence Research & Development Establishment, Jhansi Road, Gwalior, MP 474 002, India","Division of Virology, Defence Research & Development Establishment (DRDE), Jhansi Road, Gwalior, MP 474 002, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Virology, Defence Research & Development Establishment, Jhansi Road, Gwalior, MP 474 002, India","institution_ids":["https://openalex.org/I2800900741"]},{"raw_affiliation_string":"Division of Virology, Defence Research & Development Establishment (DRDE), Jhansi Road, Gwalior, MP 474 002, India","institution_ids":["https://openalex.org/I2800900741"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108463561","display_name":"Mugdha Tiwari","orcid":"https://orcid.org/0000-0002-7135-6907","observed_orcids":["https://orcid.org/0000-0002-7135-6907"]},"institutions":[{"id":"https://openalex.org/I2800900741","display_name":"Defence Research and Development Establishment","ror":"https://ror.org/04sm60f26","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1340206300","https://openalex.org/I2799351866","https://openalex.org/I2800900741","https://openalex.org/I4210150591"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Mugdha Tiwari","raw_affiliation_strings":["Division of Virology, Defence Research & Development Establishment (DRDE), Jhansi Road, Gwalior, MP 474 002, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Virology, Defence Research & Development Establishment (DRDE), Jhansi Road, Gwalior, MP 474 002, India","institution_ids":["https://openalex.org/I2800900741"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109993473","display_name":"S.R. Santhosh","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800900741","display_name":"Defence Research and Development Establishment","ror":"https://ror.org/04sm60f26","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1340206300","https://openalex.org/I2799351866","https://openalex.org/I2800900741","https://openalex.org/I4210150591"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"S.R. Santhosh","raw_affiliation_strings":["Division of Virology, Defence Research & Development Establishment (DRDE), Jhansi Road, Gwalior, MP 474 002, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Virology, Defence Research & Development Establishment (DRDE), Jhansi Road, Gwalior, MP 474 002, India","institution_ids":["https://openalex.org/I2800900741"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040776132","display_name":"Manmohan Parida","orcid":"https://orcid.org/0009-0002-6856-2221","observed_orcids":["https://orcid.org/0009-0002-6856-2221"]},"institutions":[{"id":"https://openalex.org/I2800900741","display_name":"Defence Research and Development Establishment","ror":"https://ror.org/04sm60f26","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1340206300","https://openalex.org/I2799351866","https://openalex.org/I2800900741","https://openalex.org/I4210150591"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Manmohan Parida","raw_affiliation_strings":["Division of Virology, Defence Research & Development Establishment (DRDE), Jhansi Road, Gwalior, MP 474 002, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Virology, Defence Research & Development Establishment (DRDE), Jhansi Road, Gwalior, MP 474 002, India","institution_ids":["https://openalex.org/I2800900741"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5110257960","display_name":"P. Venkata Rao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800900741","display_name":"Defence Research and Development Establishment","ror":"https://ror.org/04sm60f26","country_code":"IN","type":"facility","lineage":["https://openalex.org/I1340206300","https://openalex.org/I2799351866","https://openalex.org/I2800900741","https://openalex.org/I4210150591"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"P.V. Lakshmana Rao","raw_affiliation_strings":["Division of Virology, Defence Research & Development Establishment (DRDE), Jhansi Road, Gwalior, MP 474 002, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Virology, Defence Research & Development Establishment (DRDE), Jhansi Road, Gwalior, MP 474 002, India","institution_ids":["https://openalex.org/I2800900741"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5110257960"],"corresponding_institution_ids":["https://openalex.org/I2800900741"],"apc_list":{"value":3110,"currency":"USD","value_usd":3110},"apc_paid":null,"fwci":3.9562,"has_fulltext":false,"cited_by_count":73,"citation_normalized_percentile":{"value":0.92811913,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"376","issue":"4","first_page":"718","last_page":"722"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10166","display_name":"Mosquito-borne diseases and control","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12047","display_name":"Viral Infections and Vectors","score":0.003599999938160181,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chikungunya-virus","display_name":"chikungunya virus","score":0.9990000128746033},{"id":"https://openalex.org/keywords/rna-interference","display_name":"RNA interference","score":0.9449999928474426},{"id":"https://openalex.org/keywords/sirna","display_name":"siRNA","score":0.8629999756813049},{"id":"https://openalex.org/keywords/antiviral-therapy","display_name":"antiviral therapy","score":0.8019999861717224},{"id":"https://openalex.org/keywords/viral-replication-inhibition","display_name":"viral replication inhibition","score":0.9390000104904175},{"id":"https://openalex.org/keywords/nsp3-gene","display_name":"NSP3 gene","score":0.9580000042915344},{"id":"https://openalex.org/keywords/e1-gene","display_name":"E1 gene","score":0.9789999723434448},{"id":"https://openalex.org/keywords/vero-cells","display_name":"Vero cells","score":0.9269999861717224},{"id":"https://openalex.org/keywords/arbovirus-infection","display_name":"arbovirus infection","score":0.8090000152587891},{"id":"https://openalex.org/keywords/sirna-design","display_name":"siRNA design","score":0.460999995470047}],"concepts":[{"id":"https://openalex.org/C2781273456","wikidata":"https://www.wikidata.org/wiki/Q243257","display_name":"Chikungunya","level":3,"score":0.936005711555481},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.7751102447509766},{"id":"https://openalex.org/C22615655","wikidata":"https://www.wikidata.org/wiki/Q203221","display_name":"Small interfering RNA","level":4,"score":0.7693076133728027},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.7464215755462646},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6934958696365356},{"id":"https://openalex.org/C140704245","wikidata":"https://www.wikidata.org/wiki/Q3933202","display_name":"Viral replication","level":3,"score":0.6889715194702148},{"id":"https://openalex.org/C166703698","wikidata":"https://www.wikidata.org/wiki/Q201993","display_name":"RNA interference","level":4,"score":0.6188706159591675},{"id":"https://openalex.org/C89138240","wikidata":"https://www.wikidata.org/wiki/Q3066564","display_name":"Vero cell","level":3,"score":0.569430410861969},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.5262503027915955},{"id":"https://openalex.org/C54009773","wikidata":"https://www.wikidata.org/wiki/Q1429031","display_name":"Transfection","level":3,"score":0.4201815724372864},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3507627248764038},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13089674711227417}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002522","descriptor_name":"Chlorocebus aethiops","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002646","descriptor_name":"Chikungunya virus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002646","descriptor_name":"Chikungunya virus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014709","descriptor_name":"Vero Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D034741","descriptor_name":"RNA, Small Interfering","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.bbrc.2008.09.040","doi":"https://doi.org/10.1016/j.bbrc.2008.09.040","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.bbrc.2008.09.040","pdf_url":null,"source":{"id":"https://openalex.org/S151589183","display_name":"Biochemical and Biophysical Research Communications","issn_l":"0006-291X","issn":["0006-291X","1090-2104"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and Biophysical Research Communications","raw_type":"journal-article"},{"id":"pmid:18805396","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18805396","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemical and biophysical research communications","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W181359990","https://openalex.org/W257943533","https://openalex.org/W1510540477","https://openalex.org/W1563758392","https://openalex.org/W1611419331","https://openalex.org/W1855484651","https://openalex.org/W1969557290","https://openalex.org/W1971242896","https://openalex.org/W1988176421","https://openalex.org/W1989407131","https://openalex.org/W1995677833","https://openalex.org/W2010444790","https://openalex.org/W2016129617","https://openalex.org/W2021893534","https://openalex.org/W2030514517","https://openalex.org/W2031513436","https://openalex.org/W2034377840","https://openalex.org/W2039964691","https://openalex.org/W2048703428","https://openalex.org/W2052080135","https://openalex.org/W2067506266","https://openalex.org/W2088650511","https://openalex.org/W2092158924","https://openalex.org/W2100796404","https://openalex.org/W2105364677","https://openalex.org/W2110564957","https://openalex.org/W2112660071","https://openalex.org/W2137750232","https://openalex.org/W2138456297","https://openalex.org/W2141987735","https://openalex.org/W2158660705","https://openalex.org/W2289175135","https://openalex.org/W4211039187","https://openalex.org/W4285719527","https://openalex.org/W4285771473","https://openalex.org/W4320800933","https://openalex.org/W6765592322"],"related_works":["https://openalex.org/W2064257009","https://openalex.org/W2059146364","https://openalex.org/W2507345512","https://openalex.org/W7100984088","https://openalex.org/W4402691521","https://openalex.org/W2340900074","https://openalex.org/W4406275313","https://openalex.org/W3111964354","https://openalex.org/W4312193603","https://openalex.org/W3108500207"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":9},{"year":2012,"cited_by_count":4}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
