{"id":"https://openalex.org/W2030108536","doi":"https://doi.org/10.1016/j.ydbio.2009.05.041","title":"Blood stem cells: Regulation by the niche","display_name":"Blood stem cells: Regulation by the niche","publication_year":2009,"publication_date":"2009-06-26","ids":{"openalex":"https://openalex.org/W2030108536","doi":"https://doi.org/10.1016/j.ydbio.2009.05.041","mag":"2030108536"},"language":"en","primary_location":{"id":"doi:10.1016/j.ydbio.2009.05.041","doi":"https://doi.org/10.1016/j.ydbio.2009.05.041","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ydbio.2009.05.041","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0012160609003443/pdf","source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.sciencedirect.com/science/article/pii/S0012160609003443/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007091112","display_name":"Shane R. Mayack","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1293231726","display_name":"Joslin Diabetes Center","ror":"https://ror.org/0280a3n32","country_code":"US","type":"facility","lineage":["https://openalex.org/I1293231726"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shane R. Mayack","raw_affiliation_strings":["Joslin Diabetes Center, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Joslin Diabetes Center, Boston, MA, USA","institution_ids":["https://openalex.org/I1293231726"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067726123","display_name":"Jennifer L. Shadrach","orcid":"https://orcid.org/0000-0001-5266-8625","observed_orcids":["https://orcid.org/0000-0001-5266-8625","https://orcid.org/0009-0008-3064-118X"]},"institutions":[{"id":"https://openalex.org/I1293231726","display_name":"Joslin Diabetes Center","ror":"https://ror.org/0280a3n32","country_code":"US","type":"facility","lineage":["https://openalex.org/I1293231726"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer Shadrach","raw_affiliation_strings":["Joslin Diabetes Center, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Joslin Diabetes Center, Boston, MA, USA","institution_ids":["https://openalex.org/I1293231726"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046008593","display_name":"Koen Schepers","orcid":"https://orcid.org/0000-0003-2442-242X","observed_orcids":["https://orcid.org/0000-0003-2442-242X"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Koen Schepers","raw_affiliation_strings":["University of California, San Francisco, San Francisco, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Francisco, San Francisco, CA, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016128169","display_name":"Emmanuelle A. Passegue","orcid":"https://orcid.org/0000-0002-3516-297X","observed_orcids":["https://orcid.org/0000-0002-3516-297X"]},"institutions":[{"id":"https://openalex.org/I180670191","display_name":"University of California, San Francisco","ror":"https://ror.org/043mz5j54","country_code":"US","type":"education","lineage":["https://openalex.org/I180670191"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emmanuelle Passegue","raw_affiliation_strings":["University of California, San Francisco, San Francisco, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of California, San Francisco, San Francisco, CA, USA","institution_ids":["https://openalex.org/I180670191"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030798882","display_name":"Amy J. Wagers","orcid":"https://orcid.org/0000-0002-0066-0485","observed_orcids":["https://orcid.org/0000-0002-0066-0485"]},"institutions":[{"id":"https://openalex.org/I1293231726","display_name":"Joslin Diabetes Center","ror":"https://ror.org/0280a3n32","country_code":"US","type":"facility","lineage":["https://openalex.org/I1293231726"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy J. Wagers","raw_affiliation_strings":["Joslin Diabetes Center, Boston, MA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Joslin Diabetes Center, Boston, MA, USA","institution_ids":["https://openalex.org/I1293231726"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":{"value":0.16232703,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"331","issue":"2","first_page":"395","last_page":"395"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.014700000174343586,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/blood-stem-cells","display_name":"blood stem cells","score":0.875},{"id":"https://openalex.org/keywords/hematopoietic-stem-cell-niche","display_name":"hematopoietic niche","score":0.8109999895095825},{"id":"https://openalex.org/keywords/stem-cell-quiescence","display_name":"stem cell quiescence","score":0.6230000257492065},{"id":"https://openalex.org/keywords/cell-cycle-regulation","display_name":"cell cycle regulation","score":0.546999990940094},{"id":"https://openalex.org/keywords/ectopic-expression","display_name":"ectopic expression","score":0.38199999928474426},{"id":"https://openalex.org/keywords/knockdown","display_name":"knockdown","score":0.8840000033378601}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9440102577209473},{"id":"https://openalex.org/C153991713","wikidata":"https://www.wikidata.org/wiki/Q17142856","display_name":"Niche","level":2,"score":0.8006055355072021},{"id":"https://openalex.org/C164794517","wikidata":"https://www.wikidata.org/wiki/Q16729831","display_name":"Stem cell niche","level":4,"score":0.6014460921287537},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.5727435350418091},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.494492769241333},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.4821566939353943},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3639777898788452},{"id":"https://openalex.org/C90856448","wikidata":"https://www.wikidata.org/wiki/Q431","display_name":"Zoology","level":1,"score":0.3380417227745056},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.21014651656150818},{"id":"https://openalex.org/C201750760","wikidata":"https://www.wikidata.org/wiki/Q1896218","display_name":"Progenitor cell","level":3,"score":0.07616516947746277}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.ydbio.2009.05.041","doi":"https://doi.org/10.1016/j.ydbio.2009.05.041","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ydbio.2009.05.041","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0012160609003443/pdf","source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1016/j.ydbio.2009.05.041","doi":"https://doi.org/10.1016/j.ydbio.2009.05.041","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.ydbio.2009.05.041","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0012160609003443/pdf","source":{"id":"https://openalex.org/S136634221","display_name":"Developmental Biology","issn_l":"0012-1606","issn":["0012-1606","1095-564X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Developmental Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2030108536.pdf","grobid_xml":"https://content.openalex.org/works/W2030108536.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1979142721","https://openalex.org/W2034713769","https://openalex.org/W2518265100","https://openalex.org/W2072538882","https://openalex.org/W2230913514","https://openalex.org/W2517428798","https://openalex.org/W2157229621","https://openalex.org/W2083821412","https://openalex.org/W2598579525","https://openalex.org/W4249479818"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}