{"id":"https://openalex.org/W2030065578","doi":"https://doi.org/10.1046/j.1523-1755.1998.00984.x","title":"Concentrating defect in experimental nephrotic syndrome: Altered expression of aquaporins and thick ascending limb Na+ transporters","display_name":"Concentrating defect in experimental nephrotic syndrome: Altered expression of aquaporins and thick ascending limb Na+ transporters","publication_year":1998,"publication_date":"1998-07-01","ids":{"openalex":"https://openalex.org/W2030065578","doi":"https://doi.org/10.1046/j.1523-1755.1998.00984.x","mag":"2030065578","pmid":"https://pubmed.ncbi.nlm.nih.gov/9648076"},"language":"en","primary_location":{"id":"doi:10.1046/j.1523-1755.1998.00984.x","doi":"https://doi.org/10.1046/j.1523-1755.1998.00984.x","is_oa":true,"landing_page_url":"https://doi.org/10.1046/j.1523-1755.1998.00984.x","pdf_url":"https://www.kidney-international.org/article/S0085-2538(15)30628-1/pdf","source":{"id":"https://openalex.org/S97303050","display_name":"Kidney International","issn_l":"0085-2538","issn":["0085-2538","1523-1755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney International","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.kidney-international.org/article/S0085-2538(15)30628-1/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063987542","display_name":"Patricia Fern\u00e1ndez\u2010Llama","orcid":"https://orcid.org/0000-0002-7472-2124","observed_orcids":["https://orcid.org/0000-0002-7472-2124"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patricia Fern\u00e1ndez-Llama","raw_affiliation_strings":["Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institute of Health, Bethesda, Maryland, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institute of Health, Bethesda, Maryland, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113673062","display_name":"Peter M. Andrews","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["DK","US"],"is_corresponding":false,"raw_author_name":"Peter Andrews","raw_affiliation_strings":["Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland Department of Cell Biology, Georgetown University School of Medicine, Washington, D.C. Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark","Department of Cell Biology, Georgetown University School of Medicine, Washington, D.C","Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark","Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland Department of Cell Biology, Georgetown University School of Medicine, Washington, D.C. Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I184565670","https://openalex.org/I204337017","https://openalex.org/I4210106489"]},{"raw_affiliation_string":"Department of Cell Biology, Georgetown University School of Medicine, Washington, D.C","institution_ids":["https://openalex.org/I184565670"]},{"raw_affiliation_string":"Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark","institution_ids":["https://openalex.org/I204337017"]},{"raw_affiliation_string":"Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060168386","display_name":"CAROLYN A. ECELBARGER","orcid":"https://orcid.org/0000-0003-1222-950X","observed_orcids":["https://orcid.org/0000-0003-1222-950X"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["DK","US"],"is_corresponding":false,"raw_author_name":"Carolyn A. Ecelbarger","raw_affiliation_strings":["Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland Department of Cell Biology, Georgetown University School of Medicine, Washington, D.C. Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark","Department of Cell Biology, Georgetown University School of Medicine, Washington, D.C","Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark","Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland Department of Cell Biology, Georgetown University School of Medicine, Washington, D.C. Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I184565670","https://openalex.org/I204337017","https://openalex.org/I4210106489"]},{"raw_affiliation_string":"Department of Cell Biology, Georgetown University School of Medicine, Washington, D.C","institution_ids":["https://openalex.org/I184565670"]},{"raw_affiliation_string":"Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark","institution_ids":["https://openalex.org/I204337017"]},{"raw_affiliation_string":"Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088941482","display_name":"S\u00f8ren M\u00f8ller Nielsen","orcid":"https://orcid.org/0000-0002-4414-2508","observed_orcids":["https://orcid.org/0000-0002-4414-2508"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["DK","US"],"is_corresponding":false,"raw_author_name":"S\u00f8ren Nielsen","raw_affiliation_strings":["Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland Department of Cell Biology, Georgetown University School of Medicine, Washington, D.C. Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark","Department of Cell Biology, Georgetown University School of Medicine, Washington, D.C","Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark","Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland Department of Cell Biology, Georgetown University School of Medicine, Washington, D.C. Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I184565670","https://openalex.org/I204337017","https://openalex.org/I4210106489"]},{"raw_affiliation_string":"Department of Cell Biology, Georgetown University School of Medicine, Washington, D.C","institution_ids":["https://openalex.org/I184565670"]},{"raw_affiliation_string":"Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark","institution_ids":["https://openalex.org/I204337017"]},{"raw_affiliation_string":"Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5029048638","display_name":"Mark A. Knepper","orcid":"https://orcid.org/0000-0002-2276-8091","observed_orcids":["https://orcid.org/0000-0002-2276-8091"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]},{"id":"https://openalex.org/I4210106489","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}],"countries":["DK","US"],"is_corresponding":true,"raw_author_name":"Mark A. Knepper","raw_affiliation_strings":["Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland Department of Cell Biology, Georgetown University School of Medicine, Washington, D.C. Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark","Department of Cell Biology, Georgetown University School of Medicine, Washington, D.C","Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark","Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland Department of Cell Biology, Georgetown University School of Medicine, Washington, D.C. Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I184565670","https://openalex.org/I204337017","https://openalex.org/I4210106489"]},{"raw_affiliation_string":"Department of Cell Biology, Georgetown University School of Medicine, Washington, D.C","institution_ids":["https://openalex.org/I184565670"]},{"raw_affiliation_string":"Department of Cell Biology, Institute of Anatomy, University of Aarhus, Aarhus, Denmark","institution_ids":["https://openalex.org/I204337017"]},{"raw_affiliation_string":"Laboratory of Kidney and Electrolyte Metabolism, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210106489"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5029048638"],"corresponding_institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I184565670","https://openalex.org/I204337017","https://openalex.org/I4210106489"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":3.5247,"has_fulltext":true,"cited_by_count":107,"citation_normalized_percentile":{"value":0.93768206,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"54","issue":"1","first_page":"170","last_page":"179"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11029","display_name":"Renal Diseases and Glomerulopathies","score":0.0017000000225380063,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nephrotic-syndrome","display_name":"nephrotic syndrome","score":0.9819999933242798},{"id":"https://openalex.org/keywords/aquaporins","display_name":"aquaporins","score":0.9240000247955322},{"id":"https://openalex.org/keywords/thick-ascending-limb","display_name":"thick ascending limb","score":0.8119999766349792},{"id":"https://openalex.org/keywords/nacl-transport","display_name":"NaCl transport","score":0.6800000071525574},{"id":"https://openalex.org/keywords/nhe3","display_name":"NHE3","score":0.9179999828338623},{"id":"https://openalex.org/keywords/na-k-atpase-alpha1-subunit","display_name":"Na+/K+-ATPase alpha1 subunit","score":0.824999988079071},{"id":"https://openalex.org/keywords/aquaporin-2","display_name":"aquaporin-2","score":0.8790000081062317},{"id":"https://openalex.org/keywords/aquaporin-3","display_name":"AQP3","score":0.9729999899864197},{"id":"https://openalex.org/keywords/aquaporin-1","display_name":"aquaporin-1","score":0.9990000128746033},{"id":"https://openalex.org/keywords/adriamycin-nephropathy","display_name":"adriamycin nephropathy","score":0.875},{"id":"https://openalex.org/keywords/countercurrent-multiplication","display_name":"countercurrent multiplication","score":0.9549999833106995},{"id":"https://openalex.org/keywords/collecting-duct","display_name":"collecting duct","score":0.5870000123977661}],"concepts":[{"id":"https://openalex.org/C154280991","wikidata":"https://www.wikidata.org/wiki/Q623090","display_name":"Aquaporin","level":2,"score":0.7718822956085205},{"id":"https://openalex.org/C2778930706","wikidata":"https://www.wikidata.org/wiki/Q504790","display_name":"Nephrotic syndrome","level":2,"score":0.6785158514976501},{"id":"https://openalex.org/C149011108","wikidata":"https://www.wikidata.org/wiki/Q652985","display_name":"Transporter","level":3,"score":0.5847892761230469},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.45889899134635925},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4097481966018677},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.3913448452949524},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3643474578857422},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3172991871833801},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.1693546175956726},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09688150882720947},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000254","descriptor_name":"Sodium-Potassium-Exchanging ATPase","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D000254","descriptor_name":"Sodium-Potassium-Exchanging ATPase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000903","descriptor_name":"Antibiotics, Antineoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D002352","descriptor_name":"Carrier Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004317","descriptor_name":"Doxorubicin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D007473","descriptor_name":"Ion Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007671","descriptor_name":"Kidney Concentrating Ability","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008138","descriptor_name":"Loop of Henle","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D008138","descriptor_name":"Loop of Henle","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009088","descriptor_name":"Mucoproteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009088","descriptor_name":"Mucoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009404","descriptor_name":"Nephrotic Syndrome","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D009404","descriptor_name":"Nephrotic Syndrome","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009404","descriptor_name":"Nephrotic Syndrome","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009995","descriptor_name":"Osmosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011817","descriptor_name":"Rabbits","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013047","descriptor_name":"Specific Pathogen-Free Organisms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017923","descriptor_name":"Sodium-Hydrogen Exchangers","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D017923","descriptor_name":"Sodium-Hydrogen Exchangers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D020346","descriptor_name":"Aquaporins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D028021","descriptor_name":"Sodium-Potassium-Chloride Symporters","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051398","descriptor_name":"Aquaporin 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051399","descriptor_name":"Aquaporin 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051400","descriptor_name":"Aquaporin 3","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051403","descriptor_name":"Aquaporin 6","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058949","descriptor_name":"Uromodulin","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1046/j.1523-1755.1998.00984.x","doi":"https://doi.org/10.1046/j.1523-1755.1998.00984.x","is_oa":true,"landing_page_url":"https://doi.org/10.1046/j.1523-1755.1998.00984.x","pdf_url":"https://www.kidney-international.org/article/S0085-2538(15)30628-1/pdf","source":{"id":"https://openalex.org/S97303050","display_name":"Kidney International","issn_l":"0085-2538","issn":["0085-2538","1523-1755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney International","raw_type":"journal-article"},{"id":"pmid:9648076","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9648076","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney international","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1046/j.1523-1755.1998.00984.x","doi":"https://doi.org/10.1046/j.1523-1755.1998.00984.x","is_oa":true,"landing_page_url":"https://doi.org/10.1046/j.1523-1755.1998.00984.x","pdf_url":"https://www.kidney-international.org/article/S0085-2538(15)30628-1/pdf","source":{"id":"https://openalex.org/S97303050","display_name":"Kidney International","issn_l":"0085-2538","issn":["0085-2538","1523-1755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kidney International","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320306605","display_name":"American Society of Nephrology","ror":"https://ror.org/014pcm848"},{"id":"https://openalex.org/F4320322314","display_name":"Karen Elise Jensens Fond","ror":"https://ror.org/00kaqnj29"},{"id":"https://openalex.org/F4320322436","display_name":"Novo Nordisk","ror":"https://ror.org/0435rc536"},{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2030065578.pdf","grobid_xml":"https://content.openalex.org/works/W2030065578.grobid-xml"},"referenced_works_count":38,"referenced_works":["https://openalex.org/W218175079","https://openalex.org/W1755620559","https://openalex.org/W1845450297","https://openalex.org/W1859131610","https://openalex.org/W1870512246","https://openalex.org/W1899641734","https://openalex.org/W1963570371","https://openalex.org/W1984829055","https://openalex.org/W1994266582","https://openalex.org/W2003929885","https://openalex.org/W2004347894","https://openalex.org/W2005929901","https://openalex.org/W2029903700","https://openalex.org/W2032789959","https://openalex.org/W2033595361","https://openalex.org/W2043100266","https://openalex.org/W2048808898","https://openalex.org/W2050702143","https://openalex.org/W2063075379","https://openalex.org/W2064215706","https://openalex.org/W2075396684","https://openalex.org/W2082414348","https://openalex.org/W2086382158","https://openalex.org/W2105994341","https://openalex.org/W2118955716","https://openalex.org/W2148984043","https://openalex.org/W2154350656","https://openalex.org/W2157087554","https://openalex.org/W2173642814","https://openalex.org/W2243281268","https://openalex.org/W2298374196","https://openalex.org/W2410332910","https://openalex.org/W2412752422","https://openalex.org/W2417688203","https://openalex.org/W2433867917","https://openalex.org/W4300821970","https://openalex.org/W6684960954","https://openalex.org/W6690262403"],"related_works":["https://openalex.org/W2075396684","https://openalex.org/W2154350656","https://openalex.org/W2017209127","https://openalex.org/W4241989254","https://openalex.org/W1984893604","https://openalex.org/W2152804425","https://openalex.org/W1992879574","https://openalex.org/W7097004833","https://openalex.org/W2433864757","https://openalex.org/W2162275711"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}