{"id":"https://openalex.org/W2029653372","doi":"https://doi.org/10.1016/s0303-7207(98)00093-8","title":"Genomic characterization of the coding region of the human type II 5\u2032-deiodinase gene","display_name":"Genomic characterization of the coding region of the human type II 5\u2032-deiodinase gene","publication_year":1998,"publication_date":"1998-06-01","ids":{"openalex":"https://openalex.org/W2029653372","doi":"https://doi.org/10.1016/s0303-7207(98)00093-8","mag":"2029653372","pmid":"https://pubmed.ncbi.nlm.nih.gov/9723885"},"language":"en","primary_location":{"id":"doi:10.1016/s0303-7207(98)00093-8","doi":"https://doi.org/10.1016/s0303-7207(98)00093-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0303-7207(98)00093-8","pdf_url":null,"source":{"id":"https://openalex.org/S191044671","display_name":"Molecular and Cellular Endocrinology","issn_l":"0303-7207","issn":["0303-7207","1872-8057"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Endocrinology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043833309","display_name":"Francesco Saverio Celi","orcid":"https://orcid.org/0000-0001-7218-7052","observed_orcids":["https://orcid.org/0000-0001-7218-7052"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]},{"id":"https://openalex.org/I4210140381","display_name":"Baltimore VA Medical Center","ror":"https://ror.org/036a0e562","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210111569","https://openalex.org/I4210140381","https://openalex.org/I4210163125"]},{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT","US"],"is_corresponding":true,"raw_author_name":"Francesco S Celi","raw_affiliation_strings":["I Cattedra di Endocrinologia, Dipartimento di Medicina Sperimentale e Patologia, Universit\u00e0 degli studi di Roma La Sapienza, Italy. fsceli@hotmail.com","Division of Diabetes, Obesity and Nutrition, University of Maryland School of Medicine and the Geriatrics Research, Education and Clinical Center (GRECC), Baltimore Veterans Administration Hospital, Baltimore, MD, USA","I Cattedra di Endocrinologia, Dipartimento di Medicina Sperimentale e Patologia, Universit\u00e0 degli studi di Roma \u2018La Sapienza\u2019, Roma, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I Cattedra di Endocrinologia, Dipartimento di Medicina Sperimentale e Patologia, Universit\u00e0 degli studi di Roma La Sapienza, Italy. fsceli@hotmail.com","institution_ids":["https://openalex.org/I861853513"]},{"raw_affiliation_string":"Division of Diabetes, Obesity and Nutrition, University of Maryland School of Medicine and the Geriatrics Research, Education and Clinical Center (GRECC), Baltimore Veterans Administration Hospital, Baltimore, MD, USA","institution_ids":["https://openalex.org/I126744593","https://openalex.org/I4210140381"]},{"raw_affiliation_string":"I Cattedra di Endocrinologia, Dipartimento di Medicina Sperimentale e Patologia, Universit\u00e0 degli studi di Roma \u2018La Sapienza\u2019, Roma, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052670103","display_name":"Gianluca Canettieri","orcid":"https://orcid.org/0000-0001-6694-2613","observed_orcids":["https://orcid.org/0000-0001-6694-2613"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gianluca Canettieri","raw_affiliation_strings":["I Cattedra di Endocrinologia, Dipartimento di Medicina Sperimentale e Patologia, Universit\u00e0 degli Studi di Roma La Sapienza, Roma, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I Cattedra di Endocrinologia, Dipartimento di Medicina Sperimentale e Patologia, Universit\u00e0 degli Studi di Roma La Sapienza, Roma, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017030625","display_name":"David P. Yarnall","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800129774","display_name":"Sigma Xi","ror":"https://ror.org/04nmj5x57","country_code":"US","type":"other","lineage":["https://openalex.org/I2800129774"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David P Yarnall","raw_affiliation_strings":["Glaxo Wellcome, Research Triangle Park, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glaxo Wellcome, Research Triangle Park, NC, USA","institution_ids":["https://openalex.org/I2800129774"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084204118","display_name":"David K Burns","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800129774","display_name":"Sigma Xi","ror":"https://ror.org/04nmj5x57","country_code":"US","type":"other","lineage":["https://openalex.org/I2800129774"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David K Burns","raw_affiliation_strings":["Glaxo Wellcome, Research Triangle Park, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Glaxo Wellcome, Research Triangle Park, NC, USA","institution_ids":["https://openalex.org/I2800129774"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111696670","display_name":"Mario Andreoli","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mario Andreoli","raw_affiliation_strings":["I Cattedra di Endocrinologia, Dipartimento di Medicina Sperimentale e Patologia, Universit\u00e0 degli Studi di Roma La Sapienza, Roma, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I Cattedra di Endocrinologia, Dipartimento di Medicina Sperimentale e Patologia, Universit\u00e0 degli Studi di Roma La Sapienza, Roma, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009070946","display_name":"Alan R. Shuldiner","orcid":"https://orcid.org/0000-0001-9921-4305","observed_orcids":["https://orcid.org/0000-0001-9921-4305"]},"institutions":[{"id":"https://openalex.org/I126744593","display_name":"University of Maryland, Baltimore","ror":"https://ror.org/04rq5mt64","country_code":"US","type":"education","lineage":["https://openalex.org/I126744593"]},{"id":"https://openalex.org/I4210140381","display_name":"Baltimore VA Medical Center","ror":"https://ror.org/036a0e562","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210111569","https://openalex.org/I4210140381","https://openalex.org/I4210163125"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alan R Shuldiner","raw_affiliation_strings":["Division of Diabetes, Obesity and Nutrition, University of Maryland School of Medicine and the Geriatrics Research, Education and Clinical Center (GRECC), Baltimore Veterans Administration Hospital, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Diabetes, Obesity and Nutrition, University of Maryland School of Medicine and the Geriatrics Research, Education and Clinical Center (GRECC), Baltimore Veterans Administration Hospital, Baltimore, MD, USA","institution_ids":["https://openalex.org/I126744593","https://openalex.org/I4210140381"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050301942","display_name":"Marco Centanni","orcid":"https://orcid.org/0000-0003-0661-1649","observed_orcids":["https://orcid.org/0000-0003-0661-1649"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Marco Centanni","raw_affiliation_strings":["I Cattedra di Endocrinologia, Dipartimento di Medicina Sperimentale e Patologia, Universit\u00e0 degli Studi di Roma La Sapienza, Roma, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"I Cattedra di Endocrinologia, Dipartimento di Medicina Sperimentale e Patologia, Universit\u00e0 degli Studi di Roma La Sapienza, Roma, Italy","institution_ids":["https://openalex.org/I861853513"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5043833309"],"corresponding_institution_ids":["https://openalex.org/I126744593","https://openalex.org/I4210140381","https://openalex.org/I861853513"],"apc_list":{"value":3510,"currency":"USD","value_usd":3510},"apc_paid":null,"fwci":3.1543,"has_fulltext":false,"cited_by_count":36,"citation_normalized_percentile":{"value":0.92180264,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"141","issue":"1-2","first_page":"49","last_page":"52"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10329","display_name":"Thyroid Cancer Diagnosis and Treatment","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13563","display_name":"Chemical Analysis and Environmental Impact","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/thyroid-hormone-homeostasis","display_name":"thyroid hormone homeostasis","score":0.7889999747276306},{"id":"https://openalex.org/keywords/t4-to-t3-conversion","display_name":"T4 to T3 conversion","score":0.9470000267028809},{"id":"https://openalex.org/keywords/gene-structure","display_name":"gene structure","score":0.6740000247955322},{"id":"https://openalex.org/keywords/exon-intron-junctions","display_name":"exon-intron junctions","score":0.7080000042915344},{"id":"https://openalex.org/keywords/chromosome-localization","display_name":"chromosomal localization","score":0.8759999871253967},{"id":"https://openalex.org/keywords/radiation-hybrid-mapping","display_name":"radiation hybrid mapping","score":0.8709999918937683},{"id":"https://openalex.org/keywords/restriction-map","display_name":"restriction map","score":0.593999981880188},{"id":"https://openalex.org/keywords/infant-brain","display_name":"infant brain","score":0.5950000286102295}],"concepts":[{"id":"https://openalex.org/C94671646","wikidata":"https://www.wikidata.org/wiki/Q207551","display_name":"Intron","level":3,"score":0.7654050588607788},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7563753128051758},{"id":"https://openalex.org/C36823959","wikidata":"https://www.wikidata.org/wiki/Q373027","display_name":"Exon","level":3,"score":0.6891477108001709},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5974404811859131},{"id":"https://openalex.org/C91779695","wikidata":"https://www.wikidata.org/wiki/Q3780824","display_name":"Coding region","level":3,"score":0.5580889582633972},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5170374512672424},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3680505156517029}],"mesh":[{"descriptor_ui":"D000097564","descriptor_name":"Iodothyronine Deiodinase Type II","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002874","descriptor_name":"Chromosome Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005091","descriptor_name":"Exons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006822","descriptor_name":"Hybrid Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007438","descriptor_name":"Introns","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007453","descriptor_name":"Iodide Peroxidase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015183","descriptor_name":"Restriction Mapping","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016366","descriptor_name":"Open Reading Frames","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1016/s0303-7207(98)00093-8","doi":"https://doi.org/10.1016/s0303-7207(98)00093-8","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0303-7207(98)00093-8","pdf_url":null,"source":{"id":"https://openalex.org/S191044671","display_name":"Molecular and Cellular Endocrinology","issn_l":"0303-7207","issn":["0303-7207","1872-8057"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and Cellular Endocrinology","raw_type":"journal-article"},{"id":"pmid:9723885","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9723885","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Molecular and cellular endocrinology","raw_type":"Journal Article"},{"id":"pmh:oai:iris.uniroma1.it:11573/241965","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11573/241965","pdf_url":null,"source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5607671773","display_name":"B3 RECEPTOR GENE MUTATION IN DIABETES PRONE MINORITIES","funder_award_id":"R01DK049692","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6806013950","display_name":null,"funder_award_id":"R01DK49692-03","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1841786131","https://openalex.org/W1965534308","https://openalex.org/W1967682662","https://openalex.org/W1992080643","https://openalex.org/W1995357642","https://openalex.org/W2000933681","https://openalex.org/W2002209113","https://openalex.org/W2006140668","https://openalex.org/W2023530279","https://openalex.org/W2069613386","https://openalex.org/W2083385526","https://openalex.org/W2089378462","https://openalex.org/W2105362854","https://openalex.org/W2321598419","https://openalex.org/W2333788686","https://openalex.org/W6672649742"],"related_works":["https://openalex.org/W2102981095","https://openalex.org/W2105362854","https://openalex.org/W1965534308","https://openalex.org/W7100122557","https://openalex.org/W352758293","https://openalex.org/W2046694106","https://openalex.org/W2094231223","https://openalex.org/W2095244322","https://openalex.org/W2041002505","https://openalex.org/W2977662173"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}