{"id":"https://openalex.org/W2029335288","doi":"https://doi.org/10.1021/bi960777y","title":"The High-Affinity Sulfonylurea Receptor: Distribution, Glycosylation, Purification, and Immunoprecipitation of Two Forms from Endocrine and Neuroendocrine Cell Lines","display_name":"The High-Affinity Sulfonylurea Receptor: Distribution, Glycosylation, Purification, and Immunoprecipitation of Two Forms from Endocrine and Neuroendocrine Cell Lines","publication_year":1996,"publication_date":"1996-01-01","ids":{"openalex":"https://openalex.org/W2029335288","doi":"https://doi.org/10.1021/bi960777y","mag":"2029335288","pmid":"https://pubmed.ncbi.nlm.nih.gov/8942641"},"language":"en","primary_location":{"id":"doi:10.1021/bi960777y","doi":"https://doi.org/10.1021/bi960777y","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bi960777y","pdf_url":null,"source":{"id":"https://openalex.org/S104038378","display_name":"Biochemistry","issn_l":"0006-2960","issn":["0006-2960","1520-4995","1943-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111860576","display_name":"Daniel A. Nelson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102149020","display_name":"University of North Carolina at Charlotte","ror":"https://ror.org/04dawnj30","country_code":"US","type":"education","lineage":["https://openalex.org/I102149020"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel A. Nelson","raw_affiliation_strings":["Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, and Departments of Cell Biology and Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, and Departments of Cell Biology and Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030","institution_ids":["https://openalex.org/I102149020","https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086767351","display_name":"Joseph Bryan","orcid":"https://orcid.org/0000-0003-3476-858X","observed_orcids":["https://orcid.org/0000-0003-3476-858X"]},"institutions":[{"id":"https://openalex.org/I102149020","display_name":"University of North Carolina at Charlotte","ror":"https://ror.org/04dawnj30","country_code":"US","type":"education","lineage":["https://openalex.org/I102149020"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph Bryan","raw_affiliation_strings":["Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, and Departments of Cell Biology and Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, and Departments of Cell Biology and Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030","institution_ids":["https://openalex.org/I102149020","https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005075448","display_name":"Sergio Wechsler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102149020","display_name":"University of North Carolina at Charlotte","ror":"https://ror.org/04dawnj30","country_code":"US","type":"education","lineage":["https://openalex.org/I102149020"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S\u00e9rgio Wechsler","raw_affiliation_strings":["Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, and Departments of Cell Biology and Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, and Departments of Cell Biology and Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030","institution_ids":["https://openalex.org/I102149020","https://openalex.org/I181547552"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111625170","display_name":"Clement","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102149020","display_name":"University of North Carolina at Charlotte","ror":"https://ror.org/04dawnj30","country_code":"US","type":"education","lineage":["https://openalex.org/I102149020"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Clement","raw_affiliation_strings":["Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, and Departments of Cell Biology and Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, and Departments of Cell Biology and Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030","institution_ids":["https://openalex.org/I102149020","https://openalex.org/I181547552"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005265727","display_name":"Lydia Aguilar\u2010Bryan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I102149020","display_name":"University of North Carolina at Charlotte","ror":"https://ror.org/04dawnj30","country_code":"US","type":"education","lineage":["https://openalex.org/I102149020"]},{"id":"https://openalex.org/I181547552","display_name":"Baylor College of Medicine","ror":"https://ror.org/02pttbw34","country_code":"US","type":"education","lineage":["https://openalex.org/I181547552","https://openalex.org/I2801539370"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lydia Aguilar-Bryan","raw_affiliation_strings":["Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, and Departments of Cell Biology and Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, University of North Carolina at Charlotte, Charlotte, North Carolina 28223, and Departments of Cell Biology and Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, Texas 77030","institution_ids":["https://openalex.org/I102149020","https://openalex.org/I181547552"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":2.9046,"has_fulltext":false,"cited_by_count":34,"citation_normalized_percentile":{"value":0.906245,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":"35","issue":"47","first_page":"14793","last_page":"14799"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.8471999764442444,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10839","display_name":"Pancreatic function and diabetes","score":0.8471999764442444,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10493","display_name":"Ion channel regulation and function","score":0.1331000030040741,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10724","display_name":"Ion Transport and Channel Regulation","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/sulfonylurea-receptor","display_name":"sulfonylurea receptor","score":0.953000009059906},{"id":"https://openalex.org/keywords/atp-sensitive-potassium-channels","display_name":"ATP-sensitive potassium channels","score":0.902999997138977},{"id":"https://openalex.org/keywords/insulin-secretion","display_name":"insulin secretion","score":0.8299999833106995},{"id":"https://openalex.org/keywords/pancreatic-beta-cells","display_name":"pancreatic beta cells","score":0.8379999995231628},{"id":"https://openalex.org/keywords/glycosylation","display_name":"glycosylation","score":0.8299999833106995},{"id":"https://openalex.org/keywords/receptor-isoforms","display_name":"receptor isoforms","score":0.6759999990463257},{"id":"https://openalex.org/keywords/lectin-affinity-chromatography","display_name":"lectin affinity chromatography","score":0.8339999914169312},{"id":"https://openalex.org/keywords/receptor-purification","display_name":"receptor purification","score":0.6349999904632568},{"id":"https://openalex.org/keywords/immunoprecipitation","display_name":"immunoprecipitation","score":0.843999981880188},{"id":"https://openalex.org/keywords/tunicamycin","display_name":"tunicamycin","score":0.6100000143051147},{"id":"https://openalex.org/keywords/concanavalin-a","display_name":"concanavalin A","score":0.8009999990463257},{"id":"https://openalex.org/keywords/wheat-germ-agglutinin","display_name":"wheat germ agglutinin","score":0.9100000262260437},{"id":"https://openalex.org/keywords/anti-peptide-antibodies","display_name":"anti-peptide antibodies","score":0.7900000214576721}],"concepts":[{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.6069256067276001},{"id":"https://openalex.org/C179247698","wikidata":"https://www.wikidata.org/wiki/Q382799","display_name":"Affinity chromatography","level":3,"score":0.5726758241653442},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5261706113815308},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5016047954559326},{"id":"https://openalex.org/C185280430","wikidata":"https://www.wikidata.org/wiki/Q14909910","display_name":"Glucagon-like peptide 1 receptor","level":4,"score":0.4838608503341675},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4352148175239563},{"id":"https://openalex.org/C2777575526","wikidata":"https://www.wikidata.org/wiki/Q3542091","display_name":"Tunicamycin","level":4,"score":0.41518595814704895},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.16810542345046997},{"id":"https://openalex.org/C158617107","wikidata":"https://www.wikidata.org/wiki/Q79927","display_name":"Endoplasmic reticulum","level":2,"score":0.0},{"id":"https://openalex.org/C139447449","wikidata":"https://www.wikidata.org/wiki/Q14633900","display_name":"Unfolded protein response","level":3,"score":0.0},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002846","descriptor_name":"Chromatography, Affinity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004702","descriptor_name":"Endocrine Glands","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004702","descriptor_name":"Endocrine Glands","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006031","descriptor_name":"Glycosylation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009490","descriptor_name":"Neurosecretory Systems","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D009490","descriptor_name":"Neurosecretory Systems","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011233","descriptor_name":"Precipitin Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011955","descriptor_name":"Receptors, Drug","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011955","descriptor_name":"Receptors, Drug","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D011955","descriptor_name":"Receptors, Drug","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D012995","descriptor_name":"Solubility","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015221","descriptor_name":"Potassium Channels","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015221","descriptor_name":"Potassium Channels","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":false},{"descriptor_ui":"D015221","descriptor_name":"Potassium Channels","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018076","descriptor_name":"DNA, Complementary","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018528","descriptor_name":"ATP-Binding Cassette Transporters","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019556","descriptor_name":"COS Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D024661","descriptor_name":"Potassium Channels, Inwardly Rectifying","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D037102","descriptor_name":"Lectins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D064233","descriptor_name":"Sulfonylurea Receptors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1021/bi960777y","doi":"https://doi.org/10.1021/bi960777y","is_oa":false,"landing_page_url":"https://doi.org/10.1021/bi960777y","pdf_url":null,"source":{"id":"https://openalex.org/S104038378","display_name":"Biochemistry","issn_l":"0006-2960","issn":["0006-2960","1520-4995","1943-295X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"journal-article"},{"id":"pmid:8942641","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8942641","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biochemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4192143848","display_name":"Studies of Sulfonylurea Receptors and KATP Channels","funder_award_id":"R01DK044311","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6056844176","display_name":"SULFONYLUREA RECEPTOR CHARACTERIZATION &GENE CLONING","funder_award_id":"R01DK041898","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W1524449564","https://openalex.org/W1532205945","https://openalex.org/W1572740209","https://openalex.org/W1584699951","https://openalex.org/W1603990889","https://openalex.org/W2090888559"],"related_works":["https://openalex.org/W111516219","https://openalex.org/W1603990889","https://openalex.org/W2148959338","https://openalex.org/W1524449564","https://openalex.org/W2081857024","https://openalex.org/W1547060957","https://openalex.org/W2129475346","https://openalex.org/W1558512036","https://openalex.org/W1546726597","https://openalex.org/W2084529432"],"abstract_inverted_index":{"The":[0,20,53,102,122,150,246],"high-affinity":[1],"sulfonylurea":[2,54],"receptor,":[3],"a":[4,43,61,125,144,203],"novel":[5],"member":[6],"of":[7,15,26,63,80,97,117,128,174,232,259],"the":[8,16,35,81,137,171,180,188,194,219,230,233,238,249,260],"ATP-binding":[9],"cassette":[10],"superfamily,":[11],"is":[12,22,56,124,168,223],"one":[13],"component":[14],"ATP-sensitive":[17],"K+":[18],"channel.":[19],"protein":[21],"critical":[23],"for":[24,113,170,186,193],"regulation":[25],"insulin":[27,48],"secretion":[28],"from":[29,60],"pancreatic":[30],"beta-cells,":[31],"and":[32,65,75,87,99,139,152,161,165,211,235,251],"mutations":[33],"in":[34,58,85],"receptor":[36,55,82,123,175,201,234,244],"have":[37,105],"been":[38],"linked":[39],"to":[40,143,158,216],"familial":[41],"hyperinsulinemia,":[42],"disorder":[44],"characterized":[45],"by":[46,208],"unregulated":[47],"release":[49],"despite":[50],"severe":[51],"hypoglycemia.":[52],"present":[57,84],"membranes":[59],"number":[62],"endocrine":[64],"neuroendocrine":[66],"cell":[67],"lines,":[68],"including":[69],"HIT-T15,":[70],"RINm5f,":[71],"alpha":[72,88,131],"TC-6,":[73],"AtT-20,":[74],"GH3":[76],"cells.":[77],"Two":[78],"forms":[79,104,258],"are":[83,255],"RINm5f":[86,129],"TC-6":[89,132],"cells,":[90],"with":[91,134,202],"apparent":[92],"SDS":[93],"gel":[94],"molecular":[95],"masses":[96],"140":[98,138,151,195,220,250],"150":[100,140,153,189,252],"kDa.":[101],"two":[103],"equally":[106],"high":[107],"affinity,":[108],"KD":[109],"approximately":[110,146],"3":[111],"nM,":[112],"an":[114,119],"iodinated":[115],"derivative":[116],"glyburide,":[118],"anti-diabetic":[120],"sulfonylurea.":[121],"glycoprotein;":[126],"treatment":[127],"or":[130],"cells":[133],"tunicamycin":[135],"reduces":[136],"kDa":[141,148,154,190,196,221,253],"species":[142],"single":[145],"137":[147],"protein.":[149],"receptors":[155,254],"bind":[156],"differentially":[157,256],"concanavalin":[159],"A":[160,198],"wheat":[162],"germ":[163],"agglutinin,":[164],"lectin-affinity":[166,178],"chromatography":[167],"ideal":[169],"initial":[172],"stages":[173],"purification.":[176],"After":[177],"chromatography,":[179,210],"same":[181,261],"methods":[182],"can":[183],"be":[184],"applied":[185],"purifying":[187],"form":[191],"as":[192],"receptor.":[197],"transiently":[199],"expressed":[200],"histidine-tagged":[204],"carboxy-terminus":[205],"was":[206,214],"purified":[207],"Ni-agarose":[209],"this":[212],"variant":[213],"used":[215],"demonstrate":[217],"that":[218],"polypeptide":[222,262],"full":[224],"length.":[225],"Anti-peptide":[226],"antibodies":[227,236],"directed":[228],"against":[229,237],"amino-terminus":[231],"nucleotide":[239],"binding":[240],"folds":[241],"immunoprecipitate":[242],"both":[243],"forms.":[245],"results":[247],"indicate":[248],"glycosylated":[257],"chain.":[263]},"counts_by_year":[{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":2}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}