{"id":"https://openalex.org/W2029080751","doi":"https://doi.org/10.1039/c0cc02649b","title":"Biomimetic glass nanopores employing aptamer gates responsive to a small molecule","display_name":"Biomimetic glass nanopores employing aptamer gates responsive to a small molecule","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2029080751","doi":"https://doi.org/10.1039/c0cc02649b","mag":"2029080751","pmid":"https://pubmed.ncbi.nlm.nih.gov/20865192","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3073859"},"language":"en","primary_location":{"id":"doi:10.1039/c0cc02649b","doi":"https://doi.org/10.1039/c0cc02649b","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c0cc02649b","pdf_url":null,"source":{"id":"https://openalex.org/S152760256","display_name":"Chemical Communications","issn_l":"1359-7345","issn":["1359-7345","1364-548X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-2","ki-jl-1","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Communications","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3073859","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032277964","display_name":"Alexis E. Abelow","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexis E. Abelow","raw_affiliation_strings":["Department of Chemistry, University of Utah, 315 S. 1400 E., Salt Lake City, UT 84112-0850, USA","Department of Chemistry, University of Utah,315 S. 1400 E. Salt Lake City,USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Utah, 315 S. 1400 E., Salt Lake City, UT 84112-0850, USA","institution_ids":["https://openalex.org/I223532165"]},{"raw_affiliation_string":"Department of Chemistry, University of Utah,315 S. 1400 E. Salt Lake City,USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009867356","display_name":"Olga Schepelina","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Olga Schepelina","raw_affiliation_strings":["Department of Chemistry, University of Utah, 315 S. 1400 E. Salt Lake City, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Utah, 315 S. 1400 E. Salt Lake City, USA","institution_ids":["https://openalex.org/I223532165"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054813474","display_name":"Ryan Jeffrey White","orcid":"https://orcid.org/0000-0003-0849-0457","observed_orcids":["https://orcid.org/0000-0003-0849-0457"]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ryan J. White","raw_affiliation_strings":["Department of Chemistry and Biochemistry, and Program in Biomolecular Science and Engineering, University of California, Santa Barbara, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, and Program in Biomolecular Science and Engineering, University of California, Santa Barbara, USA","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040405132","display_name":"Alexis Vall\u00e9e\u2010B\u00e9lisle","orcid":"https://orcid.org/0000-0002-5009-7715","observed_orcids":["https://orcid.org/0000-0002-5009-7715"]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexis Vall\u00e9e-B\u00e9lisle","raw_affiliation_strings":["Department of Chemistry and Biochemistry, and Program in Biomolecular Science and Engineering, University of California, Santa Barbara, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, and Program in Biomolecular Science and Engineering, University of California, Santa Barbara, USA","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067240770","display_name":"Kevin W. Plaxco","orcid":"https://orcid.org/0000-0003-4772-8771","observed_orcids":["https://orcid.org/0000-0003-4772-8771"]},"institutions":[{"id":"https://openalex.org/I154570441","display_name":"University of California, Santa Barbara","ror":"https://ror.org/02t274463","country_code":"US","type":"education","lineage":["https://openalex.org/I154570441"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Kevin W. Plaxco","raw_affiliation_strings":["Department of Chemistry and Biochemistry, and Program in Biomolecular Science and Engineering, University of California, Santa Barbara, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry, and Program in Biomolecular Science and Engineering, University of California, Santa Barbara, USA","institution_ids":["https://openalex.org/I154570441"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5045054542","display_name":"Ilya Zharov","orcid":"https://orcid.org/0000-0002-6292-8440","observed_orcids":["https://orcid.org/0000-0002-6292-8440"]},"institutions":[{"id":"https://openalex.org/I223532165","display_name":"University of Utah","ror":"https://ror.org/03r0ha626","country_code":"US","type":"education","lineage":["https://openalex.org/I223532165"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Ilya Zharov","raw_affiliation_strings":["Department of Chemistry, University of Utah, 315 S. 1400 E. Salt Lake City, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, University of Utah, 315 S. 1400 E. Salt Lake City, USA","institution_ids":["https://openalex.org/I223532165"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5045054542","https://openalex.org/A5067240770"],"corresponding_institution_ids":["https://openalex.org/I154570441","https://openalex.org/I223532165"],"apc_list":null,"apc_paid":null,"fwci":3.0209,"has_fulltext":false,"cited_by_count":50,"citation_normalized_percentile":{"value":0.90687402,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"46","issue":"42","first_page":"7984","last_page":"7984"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11582","display_name":"Nanopore and Nanochannel Transport Studies","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T11582","display_name":"Nanopore and Nanochannel Transport Studies","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.0015999999595806003,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10913","display_name":"Molecular Junctions and Nanostructures","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glass-nanopores","display_name":"glass nanopores","score":0.9769999980926514},{"id":"https://openalex.org/keywords/dna-aptamers","display_name":"DNA aptamers","score":0.9150000214576721},{"id":"https://openalex.org/keywords/small-molecule-binding","display_name":"small molecule binding","score":0.609000027179718},{"id":"https://openalex.org/keywords/molecular-transport","display_name":"molecular transport","score":0.7559999823570251},{"id":"https://openalex.org/keywords/surface-modification","display_name":"surface modification","score":0.5720000267028809},{"id":"https://openalex.org/keywords/nanopore-sensors","display_name":"nanopore sensors","score":0.44200000166893005}],"concepts":[{"id":"https://openalex.org/C141795571","wikidata":"https://www.wikidata.org/wiki/Q580942","display_name":"Nanopore","level":2,"score":0.9756222367286682},{"id":"https://openalex.org/C128972844","wikidata":"https://www.wikidata.org/wiki/Q418722","display_name":"Aptamer","level":2,"score":0.9564837217330933},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.6836346387863159},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.66165691614151},{"id":"https://openalex.org/C161624437","wikidata":"https://www.wikidata.org/wiki/Q1988322","display_name":"Small molecule","level":2,"score":0.5773789882659912},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5616581439971924},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.41003701090812683},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.30148959159851074},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.05075573921203613},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005898","descriptor_name":"Glass","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D032701","descriptor_name":"Biomimetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D049329","descriptor_name":"Nanostructures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D052157","descriptor_name":"Aptamers, Nucleotide","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1039/c0cc02649b","doi":"https://doi.org/10.1039/c0cc02649b","is_oa":false,"landing_page_url":"https://doi.org/10.1039/c0cc02649b","pdf_url":null,"source":{"id":"https://openalex.org/S152760256","display_name":"Chemical Communications","issn_l":"1359-7345","issn":["1359-7345","1364-548X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-2","ki-jl-1","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320556","host_organization_name":"Royal Society of Chemistry","host_organization_lineage":["https://openalex.org/P4310320556"],"host_organization_lineage_names":["Royal Society of Chemistry"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical Communications","raw_type":"journal-article"},{"id":"pmid:20865192","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20865192","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemical communications (Cambridge, England)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:3073859","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3073859","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Chem Commun (Camb)","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:3073859","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3073859","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Chem Commun (Camb)","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1840169102","display_name":"Electrochemical arrays for the detection of small molecule drugs","funder_award_id":"R01EB007689","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"},{"id":"https://openalex.org/G1878536253","display_name":"Rapid Electronic Detection of Drug Analytes in Blood","funder_award_id":"5f32gm087126-02","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G5616051870","display_name":null,"funder_award_id":"F32 GM087126","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G8502628143","display_name":null,"funder_award_id":"1 F32 GM087126-01A1","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W1627543519","https://openalex.org/W1969035105","https://openalex.org/W1974162384","https://openalex.org/W1984834241","https://openalex.org/W1988018356","https://openalex.org/W1991674727","https://openalex.org/W1997511581","https://openalex.org/W1997647778","https://openalex.org/W1997698671","https://openalex.org/W2007385957","https://openalex.org/W2017945293","https://openalex.org/W2030202736","https://openalex.org/W2036025200","https://openalex.org/W2043720689","https://openalex.org/W2044864474","https://openalex.org/W2045889911","https://openalex.org/W2048407638","https://openalex.org/W2057336773","https://openalex.org/W2079321730","https://openalex.org/W2081498427","https://openalex.org/W2081737898","https://openalex.org/W2082528246","https://openalex.org/W2088260140","https://openalex.org/W2089124524","https://openalex.org/W2091047025","https://openalex.org/W2104525153","https://openalex.org/W2110584587","https://openalex.org/W2139446350","https://openalex.org/W2149005864","https://openalex.org/W2169243602","https://openalex.org/W2950430077"],"related_works":["https://openalex.org/W2051525874","https://openalex.org/W4235048364","https://openalex.org/W1997698671","https://openalex.org/W1524785155","https://openalex.org/W4386817830","https://openalex.org/W4412630232","https://openalex.org/W2312040641","https://openalex.org/W4416595219","https://openalex.org/W4405587907","https://openalex.org/W2337504099"],"abstract_inverted_index":{"We":[0],"report":[1],"the":[2,20,24],"preparation":[3],"of":[4],"20":[5],"and":[6],"65":[7],"nm":[8],"radii":[9],"glass":[10],"nanopores":[11,25],"whose":[12],"surface":[13],"is":[14],"modified":[15],"with":[16],"DNA":[17],"aptamers":[18],"controlling":[19],"molecular":[21],"transport":[22],"through":[23],"in":[26],"response":[27],"to":[28],"small":[29],"molecule":[30],"binding.":[31]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":7}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}