{"id":"https://openalex.org/W2029014698","doi":"https://doi.org/10.1016/0002-9149(82)90521-5","title":"Randomized double-blind comparison of nifedipine and isosorbide dinitrate in patients with coronary arterial spasm","display_name":"Randomized double-blind comparison of nifedipine and isosorbide dinitrate in patients with coronary arterial spasm","publication_year":1982,"publication_date":"1982-02-01","ids":{"openalex":"https://openalex.org/W2029014698","doi":"https://doi.org/10.1016/0002-9149(82)90521-5","mag":"2029014698","pmid":"https://pubmed.ncbi.nlm.nih.gov/6800251"},"language":"en","primary_location":{"id":"doi:10.1016/0002-9149(82)90521-5","doi":"https://doi.org/10.1016/0002-9149(82)90521-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0002-9149(82)90521-5","pdf_url":null,"source":{"id":"https://openalex.org/S185186944","display_name":"The American Journal of Cardiology","issn_l":"0002-9149","issn":["0002-9149","1879-1913"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Cardiology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5103498076","display_name":"James A. Hill","orcid":"https://orcid.org/0000-0003-0528-1270","observed_orcids":["https://orcid.org/0000-0003-0528-1270"]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]},{"id":"https://openalex.org/I2800717037","display_name":"University of Florida Health","ror":"https://ror.org/04tk2gy88","country_code":"US","type":"education","lineage":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]},{"id":"https://openalex.org/I4210118777","display_name":"North Florida/South Georgia Veterans Health System","ror":"https://ror.org/02r7md321","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210118777","https://openalex.org/I4210119004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James A. Hill","raw_affiliation_strings":["From the Division of Cardiology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA","Veterans Administration Medical Center, Gainesville, Florida, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Cardiology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA","institution_ids":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"raw_affiliation_string":"Veterans Administration Medical Center, Gainesville, Florida, USA","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210118777"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5106893338","display_name":"Robert L. Feldman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]},{"id":"https://openalex.org/I2800717037","display_name":"University of Florida Health","ror":"https://ror.org/04tk2gy88","country_code":"US","type":"education","lineage":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]},{"id":"https://openalex.org/I4210118777","display_name":"North Florida/South Georgia Veterans Health System","ror":"https://ror.org/02r7md321","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210118777","https://openalex.org/I4210119004"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert L. Feldman","raw_affiliation_strings":["From the Division of Cardiology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA","Veterans Administration Medical Center, Gainesville, Florida, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Cardiology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA","institution_ids":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"raw_affiliation_string":"Veterans Administration Medical Center, Gainesville, Florida, USA","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210118777"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065188755","display_name":"Carl J. Pepine","orcid":"https://orcid.org/0000-0002-6011-681X","observed_orcids":["https://orcid.org/0000-0002-6011-681X"]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]},{"id":"https://openalex.org/I2800717037","display_name":"University of Florida Health","ror":"https://ror.org/04tk2gy88","country_code":"US","type":"education","lineage":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]},{"id":"https://openalex.org/I4210118777","display_name":"North Florida/South Georgia Veterans Health System","ror":"https://ror.org/02r7md321","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210118777","https://openalex.org/I4210119004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carl J. Pepine","raw_affiliation_strings":["From the Division of Cardiology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA","Veterans Administration Medical Center, Gainesville, Florida, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Cardiology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA","institution_ids":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"raw_affiliation_string":"Veterans Administration Medical Center, Gainesville, Florida, USA","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210118777"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5109850123","display_name":"C. Richard Conti","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1322918889","display_name":"United States Department of Veterans Affairs","ror":"https://ror.org/05rsv9s98","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889"]},{"id":"https://openalex.org/I2799886695","display_name":"Veterans Health Administration","ror":"https://ror.org/05eq41471","country_code":"US","type":"government","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695"]},{"id":"https://openalex.org/I2800717037","display_name":"University of Florida Health","ror":"https://ror.org/04tk2gy88","country_code":"US","type":"education","lineage":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"id":"https://openalex.org/I33213144","display_name":"University of Florida","ror":"https://ror.org/02y3ad647","country_code":"US","type":"education","lineage":["https://openalex.org/I33213144"]},{"id":"https://openalex.org/I4210118777","display_name":"North Florida/South Georgia Veterans Health System","ror":"https://ror.org/02r7md321","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210118777","https://openalex.org/I4210119004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C.Richard Conti","raw_affiliation_strings":["From the Division of Cardiology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA","Veterans Administration Medical Center, Gainesville, Florida, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"From the Division of Cardiology, Department of Medicine, University of Florida College of Medicine, Gainesville, Florida, USA","institution_ids":["https://openalex.org/I2800717037","https://openalex.org/I33213144"]},{"raw_affiliation_string":"Veterans Administration Medical Center, Gainesville, Florida, USA","institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I4210118777"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5106893338"],"corresponding_institution_ids":["https://openalex.org/I1322918889","https://openalex.org/I2799886695","https://openalex.org/I2800717037","https://openalex.org/I33213144","https://openalex.org/I4210118777"],"apc_list":{"value":3380,"currency":"USD","value_usd":3380},"apc_paid":null,"fwci":13.6906,"has_fulltext":false,"cited_by_count":106,"citation_normalized_percentile":{"value":0.99071949,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"49","issue":"2","first_page":"431","last_page":"438"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13381","display_name":"Heart rate and cardiovascular health","score":0.7738999724388123,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T13381","display_name":"Heart rate and cardiovascular health","score":0.7738999724388123,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.08160000294446945,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.03680000081658363,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nifedipine","display_name":"nifedipine","score":0.953000009059906},{"id":"https://openalex.org/keywords/isosorbide-dinitrate","display_name":"isosorbide dinitrate","score":1.0},{"id":"https://openalex.org/keywords/coronary-spasm","display_name":"coronary vasospasm","score":0.8849999904632568},{"id":"https://openalex.org/keywords/angina","display_name":"angina pectoris","score":0.9210000038146973},{"id":"https://openalex.org/keywords/nitroglycerin-consumption","display_name":"nitroglycerin consumption","score":0.7609999775886536},{"id":"https://openalex.org/keywords/calcium-channel-blockers","display_name":"calcium channel blockers","score":0.8460000157356262},{"id":"https://openalex.org/keywords/vasodilator-therapy","display_name":"vasodilator therapy","score":0.796999990940094},{"id":"https://openalex.org/keywords/comparative-efficacy","display_name":"drug efficacy comparison","score":0.6700000166893005}],"concepts":[{"id":"https://openalex.org/C2778949068","wikidata":"https://www.wikidata.org/wiki/Q179748","display_name":"Isosorbide dinitrate","level":2,"score":0.9723690748214722},{"id":"https://openalex.org/C2779066535","wikidata":"https://www.wikidata.org/wiki/Q39111","display_name":"Nifedipine","level":3,"score":0.8790643215179443},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.622771680355072},{"id":"https://openalex.org/C2991744798","wikidata":"https://www.wikidata.org/wiki/Q608510","display_name":"Double blind","level":4,"score":0.5500480532646179},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.4688500165939331},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.45307254791259766},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.4375608563423157},{"id":"https://openalex.org/C2776915459","wikidata":"https://www.wikidata.org/wiki/Q1243800","display_name":"Isosorbide","level":2,"score":0.43502819538116455},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.42387229204177856},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.08664298057556152},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.07329002022743225},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.05726742744445801},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000787","descriptor_name":"Angina Pectoris","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D000790","descriptor_name":"Angiocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002986","descriptor_name":"Clinical Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003329","descriptor_name":"Coronary Vasospasm","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D003329","descriptor_name":"Coronary Vasospasm","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003329","descriptor_name":"Coronary Vasospasm","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004341","descriptor_name":"Drug Evaluation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004562","descriptor_name":"Electrocardiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005996","descriptor_name":"Nitroglycerin","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006261","descriptor_name":"Headache","qualifier_ui":"Q000139","qualifier_name":"chemically induced","is_major_topic":false},{"descriptor_ui":"D006352","descriptor_name":"Heart Ventricles","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007548","descriptor_name":"Isosorbide Dinitrate","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D007548","descriptor_name":"Isosorbide Dinitrate","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009543","descriptor_name":"Nifedipine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D009543","descriptor_name":"Nifedipine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011725","descriptor_name":"Pyridines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0002-9149(82)90521-5","doi":"https://doi.org/10.1016/0002-9149(82)90521-5","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0002-9149(82)90521-5","pdf_url":null,"source":{"id":"https://openalex.org/S185186944","display_name":"The American Journal of Cardiology","issn_l":"0002-9149","issn":["0002-9149","1879-1913"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Cardiology","raw_type":"journal-article"},{"id":"pmid:6800251","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6800251","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of cardiology","raw_type":"Clinical Trial"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/randomized-controlled-trial","display_name":"Randomized Controlled Trial"},{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W125918038","https://openalex.org/W1526871402","https://openalex.org/W1968602190","https://openalex.org/W1982697362","https://openalex.org/W1984880976","https://openalex.org/W1989398072","https://openalex.org/W1993547522","https://openalex.org/W2002800876","https://openalex.org/W2007660399","https://openalex.org/W2021456091","https://openalex.org/W2028848355","https://openalex.org/W2029084490","https://openalex.org/W2029199886","https://openalex.org/W2030328018","https://openalex.org/W2030769821","https://openalex.org/W2039020636","https://openalex.org/W2072669657","https://openalex.org/W2081999049","https://openalex.org/W2095094423","https://openalex.org/W2096555817","https://openalex.org/W2100179138","https://openalex.org/W2106964838","https://openalex.org/W2107273075","https://openalex.org/W2129315044","https://openalex.org/W2144416016","https://openalex.org/W2341926292","https://openalex.org/W2410420279","https://openalex.org/W2468880269","https://openalex.org/W4246386179","https://openalex.org/W4318445388"],"related_works":["https://openalex.org/W2101494373","https://openalex.org/W2088886307","https://openalex.org/W2072669657","https://openalex.org/W2068315244","https://openalex.org/W2074233912","https://openalex.org/W2587649282","https://openalex.org/W2413214137","https://openalex.org/W2030769821","https://openalex.org/W2053255232","https://openalex.org/W60201603"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":3},{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}