{"id":"https://openalex.org/W2028862249","doi":"https://doi.org/10.1172/jci109980","title":"Dual parameter flow cytometry studies in human lymphomas.","display_name":"Dual parameter flow cytometry studies in human lymphomas.","publication_year":1980,"publication_date":"1980-12-01","ids":{"openalex":"https://openalex.org/W2028862249","doi":"https://doi.org/10.1172/jci109980","mag":"2028862249","pmid":"https://pubmed.ncbi.nlm.nih.gov/6969266","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/371613"},"language":"es","primary_location":{"id":"doi:10.1172/jci109980","doi":"https://doi.org/10.1172/jci109980","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci109980","pdf_url":"http://www.jci.org/articles/view/109980/files/pdf","source":{"id":"https://openalex.org/S114430552","display_name":"Journal of Clinical Investigation","issn_l":"0021-9738","issn":["0021-9738","1558-8238"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Investigation","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.jci.org/articles/view/109980/files/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5027859218","display_name":"Stanley E. Shackney","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"S E Shackney","raw_affiliation_strings":["Clinical Pharmacology Branch , Diu","ision of Cancer Treatment , National Cancer Institute , Bethesda , Maryland 20205 ;","Clinical Pharmacology Branch, Diu ision of Cancer Treatment, National Cancer Institute, Bethesda, Maryland 20205; Department of Pathology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Pharmacology Branch , Diu","institution_ids":[]},{"raw_affiliation_string":"ision of Cancer Treatment , National Cancer Institute , Bethesda , Maryland 20205 ;","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"raw_affiliation_string":"Clinical Pharmacology Branch, Diu ision of Cancer Treatment, National Cancer Institute, Bethesda, Maryland 20205; Department of Pathology,","institution_ids":["https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085526208","display_name":"K S Skramstad","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"K S Skramstad","raw_affiliation_strings":["Clinical Pharmacology Branch , Diu","ision of Cancer Treatment , National Cancer Institute , Bethesda , Maryland 20205 ;","Clinical Pharmacology Branch, Diu ision of Cancer Treatment, National Cancer Institute, Bethesda, Maryland 20205; Department of Pathology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Pharmacology Branch , Diu","institution_ids":[]},{"raw_affiliation_string":"ision of Cancer Treatment , National Cancer Institute , Bethesda , Maryland 20205 ;","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"raw_affiliation_string":"Clinical Pharmacology Branch, Diu ision of Cancer Treatment, National Cancer Institute, Bethesda, Maryland 20205; Department of Pathology,","institution_ids":["https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108464837","display_name":"R E Cunningham","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R E Cunningham","raw_affiliation_strings":["Clinical Pharmacology Branch , Diu","ision of Cancer Treatment , National Cancer Institute , Bethesda , Maryland 20205 ;","Clinical Pharmacology Branch, Diu ision of Cancer Treatment, National Cancer Institute, Bethesda, Maryland 20205; Department of Pathology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Pharmacology Branch , Diu","institution_ids":[]},{"raw_affiliation_string":"ision of Cancer Treatment , National Cancer Institute , Bethesda , Maryland 20205 ;","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"raw_affiliation_string":"Clinical Pharmacology Branch, Diu ision of Cancer Treatment, National Cancer Institute, Bethesda, Maryland 20205; Department of Pathology,","institution_ids":["https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031049415","display_name":"D. J. Dugas","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D J Dugas","raw_affiliation_strings":["Clinical Pharmacology Branch , Diu","ision of Cancer Treatment , National Cancer Institute , Bethesda , Maryland 20205 ;","Clinical Pharmacology Branch, Diu ision of Cancer Treatment, National Cancer Institute, Bethesda, Maryland 20205; Department of Pathology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Pharmacology Branch , Diu","institution_ids":[]},{"raw_affiliation_string":"ision of Cancer Treatment , National Cancer Institute , Bethesda , Maryland 20205 ;","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"raw_affiliation_string":"Clinical Pharmacology Branch, Diu ision of Cancer Treatment, National Cancer Institute, Bethesda, Maryland 20205; Department of Pathology,","institution_ids":["https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104050419","display_name":"Thomas L. Lincoln","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"T L Lincoln","raw_affiliation_strings":["Clinical Pharmacology Branch , Diu","ision of Cancer Treatment , National Cancer Institute , Bethesda , Maryland 20205 ;","Clinical Pharmacology Branch, Diu ision of Cancer Treatment, National Cancer Institute, Bethesda, Maryland 20205; Department of Pathology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Pharmacology Branch , Diu","institution_ids":[]},{"raw_affiliation_string":"ision of Cancer Treatment , National Cancer Institute , Bethesda , Maryland 20205 ;","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210140884"]},{"raw_affiliation_string":"Clinical Pharmacology Branch, Diu ision of Cancer Treatment, National Cancer Institute, Bethesda, Maryland 20205; Department of Pathology,","institution_ids":["https://openalex.org/I4210140884"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063097452","display_name":"RJ Lukes","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"R J Lukes","raw_affiliation_strings":["Clinical Pharmacology Branch, Diu ision of Cancer Treatment, National Cancer Institute, Bethesda, Maryland 20205; Department of Pathology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Pharmacology Branch, Diu ision of Cancer Treatment, National Cancer Institute, Bethesda, Maryland 20205; Department of Pathology,","institution_ids":["https://openalex.org/I4210140884"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5200,"currency":"USD","value_usd":5200},"apc_paid":null,"fwci":3.7211,"has_fulltext":true,"cited_by_count":47,"citation_normalized_percentile":{"value":0.917671,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":null,"biblio":{"volume":"66","issue":"6","first_page":"1281","last_page":"1294"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.9922000169754028,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10950","display_name":"Acute Lymphoblastic Leukemia research","score":0.0007999999797903001,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lymphoma","display_name":"lymphoma","score":0.859000027179718},{"id":"https://openalex.org/keywords/cell-size","display_name":"cell size","score":0.46700000762939453},{"id":"https://openalex.org/keywords/dna-content","display_name":"DNA content","score":0.8619999885559082},{"id":"https://openalex.org/keywords/cell-cycle-distribution","display_name":"cell cycle distribution","score":0.7120000123977661},{"id":"https://openalex.org/keywords/s-phase","display_name":"S phase","score":0.43299999833106995},{"id":"https://openalex.org/keywords/aneuploidy","display_name":"aneuploidy","score":0.8399999737739563},{"id":"https://openalex.org/keywords/large-b-cell-lymphoma","display_name":"large B-cell lymphoma","score":0.8119999766349792},{"id":"https://openalex.org/keywords/t-cell-lymphoma","display_name":"T-cell lymphoma","score":0.9750000238418579},{"id":"https://openalex.org/keywords/chronic-lymphocytic-leukemia","display_name":"chronic lymphocytic leukemia","score":0.8920000195503235},{"id":"https://openalex.org/keywords/hairy-cell-leukemia","display_name":"hairy cell leukemia","score":0.9990000128746033},{"id":"https://openalex.org/keywords/clonal-evolution","display_name":"clonal evolution","score":0.7319999933242798},{"id":"https://openalex.org/keywords/tumor-cell-proliferation","display_name":"tumor cell proliferation","score":0.5210000276565552}],"concepts":[{"id":"https://openalex.org/C206772107","wikidata":"https://www.wikidata.org/wiki/Q2006868","display_name":"Coulter counter","level":2,"score":0.7965347766876221},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.7658727169036865},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.576714277267456},{"id":"https://openalex.org/C2779672484","wikidata":"https://www.wikidata.org/wiki/Q529622","display_name":"Aneuploidy","level":4,"score":0.5416813492774963},{"id":"https://openalex.org/C2780339063","wikidata":"https://www.wikidata.org/wiki/Q5201367","display_name":"Cytometry","level":3,"score":0.5349961519241333},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.49987220764160156},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.49449798464775085},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.44949716329574585},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4425400495529175},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.41786038875579834},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3087161183357239},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.21098405122756958},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1086951196193695},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000782","descriptor_name":"Aneuploidy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D002453","descriptor_name":"Cell Cycle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004273","descriptor_name":"DNA, Neoplasm","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005470","descriptor_name":"Fluorometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006689","descriptor_name":"Hodgkin Disease","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007943","descriptor_name":"Leukemia, Hairy Cell","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D007945","descriptor_name":"Leukemia, Lymphoid","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008223","descriptor_name":"Lymphoma","qualifier_ui":"Q000145","qualifier_name":"classification","is_major_topic":false},{"descriptor_ui":"D008223","descriptor_name":"Lymphoma","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1172/jci109980","doi":"https://doi.org/10.1172/jci109980","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci109980","pdf_url":"http://www.jci.org/articles/view/109980/files/pdf","source":{"id":"https://openalex.org/S114430552","display_name":"Journal of Clinical Investigation","issn_l":"0021-9738","issn":["0021-9738","1558-8238"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Investigation","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:371613","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/371613","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Clin Invest","raw_type":"Text"},{"id":"pmid:6969266","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/6969266","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of clinical investigation","raw_type":"Journal Article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.824.8179","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.824.8179","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://dm5migu4zj3pb.cloudfront.net/manuscripts/109000/109980/JCI80109980.pdf","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1172/jci109980","doi":"https://doi.org/10.1172/jci109980","is_oa":true,"landing_page_url":"https://doi.org/10.1172/jci109980","pdf_url":"http://www.jci.org/articles/view/109980/files/pdf","source":{"id":"https://openalex.org/S114430552","display_name":"Journal of Clinical Investigation","issn_l":"0021-9738","issn":["0021-9738","1558-8238"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320279","host_organization_name":"American Society for Clinical Investigation","host_organization_lineage":["https://openalex.org/P4310320279"],"host_organization_lineage_names":["American Society for Clinical Investigation"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Investigation","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2028862249.pdf","grobid_xml":"https://content.openalex.org/works/W2028862249.grobid-xml"},"referenced_works_count":53,"referenced_works":["https://openalex.org/W50576027","https://openalex.org/W124127999","https://openalex.org/W262910656","https://openalex.org/W266998131","https://openalex.org/W1531921951","https://openalex.org/W1548038310","https://openalex.org/W1600540509","https://openalex.org/W1603941990","https://openalex.org/W1967082515","https://openalex.org/W1967304777","https://openalex.org/W1971432519","https://openalex.org/W1973976655","https://openalex.org/W1974512789","https://openalex.org/W1980429620","https://openalex.org/W1981498836","https://openalex.org/W1985348935","https://openalex.org/W1985938059","https://openalex.org/W1989734105","https://openalex.org/W1995586052","https://openalex.org/W2004245707","https://openalex.org/W2012445133","https://openalex.org/W2014407670","https://openalex.org/W2016734648","https://openalex.org/W2017691475","https://openalex.org/W2030964932","https://openalex.org/W2033870370","https://openalex.org/W2036089223","https://openalex.org/W2042590058","https://openalex.org/W2049946525","https://openalex.org/W2053954055","https://openalex.org/W2062083551","https://openalex.org/W2062138707","https://openalex.org/W2062668405","https://openalex.org/W2073995560","https://openalex.org/W2074105540","https://openalex.org/W2085466592","https://openalex.org/W2086930942","https://openalex.org/W2106608507","https://openalex.org/W2135635705","https://openalex.org/W2146887423","https://openalex.org/W2152405926","https://openalex.org/W2153987325","https://openalex.org/W2162864784","https://openalex.org/W2277918015","https://openalex.org/W2316080730","https://openalex.org/W2341862247","https://openalex.org/W2400933597","https://openalex.org/W2401634607","https://openalex.org/W2414530373","https://openalex.org/W2414855633","https://openalex.org/W2415007930","https://openalex.org/W2417981182","https://openalex.org/W2429958701"],"related_works":["https://openalex.org/W7098027020","https://openalex.org/W2124704075","https://openalex.org/W2341862247","https://openalex.org/W1603941990","https://openalex.org/W2103836142","https://openalex.org/W1985348935","https://openalex.org/W1892956898","https://openalex.org/W2119562932","https://openalex.org/W2013083273","https://openalex.org/W2329532347"],"abstract_inverted_index":{"Dual":[0],"parameter":[1],"flow":[2,196],"cytometry":[3,197],"studies":[4],"using":[5],"Coulter":[6,38,54,88,106,128,222],"volume":[7,39,55,89,107,129,223],"and":[8,31,56,66,130,174,178,265,274],"cell":[9,17,29,53,74,127,143,182,190,206,215,221],"DNA":[10],"content":[11],"were":[12,43],"carried":[13],"out":[14],"in":[15,36,50,100,113,138,166,170,175,179,187,198,201,239,256,266],"monodisperse":[16],"suspensions":[18],"of":[19,22,60,63,80,98,133,136,220,228,241,262,271,277],"64":[20],"samples":[21,114,173],"human":[23],"lymphoma,":[24],"chronic":[25],"lymphocytic":[26],"leukemia,":[27,30],"hairy":[28],"benign":[32],"lymphoid":[33],"proliferations.":[34],"Differences":[35],"mean":[37,51,105,125],"among":[40,70,140],"the":[41,47,58,71,77,85,96,131,134,141,171,176,180,188,204,213,218,236,259,263,269],"lymphomas":[42,144,183],"due":[44],"both":[45,169],"to":[46,57,84,258,268],"intrinsic":[48],"differences":[49],"G1":[52,126],"presence":[59,97],"increased":[61],"fractions":[62,234],"larger":[64],"S":[65,101,117,139,233],"G2":[67],"cells,":[68],"especially":[69],"large":[72,81,155],"B":[73,142,189],"lymphomas.":[75,191],"However,":[76],"relative":[78],"contribution":[79],"non-G1":[82],"cells":[83,99,137,156],"overall":[86],"population":[87],"distribution":[90],"was":[91,120,164,193],"a":[92,121],"relatively":[93],"minor":[94],"one;":[95],"did":[102],"not":[103],"increase":[104],"by":[108,195],"more":[109,158],"than":[110,160,235],"10%,":[111],"even":[112],"with":[115],"high":[116],"fractions.":[118],"There":[119],"good":[122],"correlation":[123],"between":[124],"log":[132],"fraction":[135],"(r":[145],"=":[146],"0.55).":[147],"Evidence":[148],"is":[149],"presented":[150],"that":[151],"within":[152],"individual":[153],"samples,":[154],"proliferate":[157],"rapidly":[159],"small":[161],"cells.":[162],"This":[163],"seen":[165],"every":[167],"case,":[168],"normal":[172],"lymphomas,":[177,264],"T":[181],"as":[184,186],"well":[185],"Aneuploidy":[192],"detected":[194],"11":[199],"cases;":[200],"7":[202],"cases":[203,243],"aneuploid":[205,226],"component":[207,216],"could":[208],"be":[209],"analyzed":[210],"separately":[211],"from":[212],"diploid":[214,237],"on":[217],"basis":[219],"differences.":[224],"The":[225],"components":[227,238],"diploid-aneuploid":[229],"mixtures":[230],"had":[231],"higher":[232],"six":[240],"seven":[242],"(0.16":[244],"+/-":[245,250],"0.04":[246],"[SE]":[247],"vs.":[248],"0.08":[249],"0.02).":[251],"These":[252],"findings":[253],"are":[254],"considered":[255],"relation":[257,267],"histopathological":[260],"classification":[261],"concept":[270],"clonal":[272,275],"selection":[273],"evolution":[276],"tumors.":[278]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}