{"id":"https://openalex.org/W2028264382","doi":"https://doi.org/10.1111/j.1439-0450.1995.tb00682.x","title":"Isolation of the Major Outer\u2010membrane Protein of Actinobacillus pleuropneumonias and Haemophilus parasuis","display_name":"Isolation of the Major Outer\u2010membrane Protein of Actinobacillus pleuropneumonias and Haemophilus parasuis","publication_year":1995,"publication_date":"1995-01-12","ids":{"openalex":"https://openalex.org/W2028264382","doi":"https://doi.org/10.1111/j.1439-0450.1995.tb00682.x","mag":"2028264382","pmid":"https://pubmed.ncbi.nlm.nih.gov/7483902"},"language":"en","primary_location":{"id":"doi:10.1111/j.1439-0450.1995.tb00682.x","doi":"https://doi.org/10.1111/j.1439-0450.1995.tb00682.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1439-0450.1995.tb00682.x","pdf_url":null,"source":{"id":"https://openalex.org/S195337790","display_name":"Journal of Veterinary Medicine Series B","issn_l":"0931-1793","issn":["0931-1793","1439-0450"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Veterinary Medicine, Series B","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2028264382"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075504136","display_name":"Ludger Hartmann","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"L. Hartmann","raw_affiliation_strings":["Institut f\u00fcr Mikrobiologie und Tierseuchen, Freie Universit\u00e4t Berlin, Germany","Institut fu\u0308r Biochemie, SFB 344, Freie Universita\u0308t Berlin, D-14195 Berlin, Germany","Institut fu\u0308r Mikrobiologie und Tierseuchen, Fachbereich Veterina\u0308rmedizin","Institut fu\u0308r Mikrobiologie und Tierseuchen, Freie Universita\u0308t Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut f\u00fcr Mikrobiologie und Tierseuchen, Freie Universit\u00e4t Berlin, Germany","institution_ids":["https://openalex.org/I75951250"]},{"raw_affiliation_string":"Institut fu\u0308r Biochemie, SFB 344, Freie Universita\u0308t Berlin, D-14195 Berlin, Germany","institution_ids":["https://openalex.org/I75951250"]},{"raw_affiliation_string":"Institut fu\u0308r Mikrobiologie und Tierseuchen, Fachbereich Veterina\u0308rmedizin","institution_ids":[]},{"raw_affiliation_string":"Institut fu\u0308r Mikrobiologie und Tierseuchen, Freie Universita\u0308t Berlin, Germany","institution_ids":["https://openalex.org/I75951250"]}]},{"author_position":"middle","author":{"id":null,"display_name":"W. Schr\u00f6der","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"W. Schr\u00f6der","raw_affiliation_strings":["Institut fu\u0308r Biochemie, SFB 344, Freie Universita\u0308t Berlin, D-14195 Berlin, Germany","Institut fu\u0308r Mikrobiologie und Tierseuchen, Fachbereich Veterina\u0308rmedizin","Institut fu\u0308r Mikrobiologie und Tierseuchen, Freie Universita\u0308t Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut fu\u0308r Biochemie, SFB 344, Freie Universita\u0308t Berlin, D-14195 Berlin, Germany","institution_ids":["https://openalex.org/I75951250"]},{"raw_affiliation_string":"Institut fu\u0308r Mikrobiologie und Tierseuchen, Fachbereich Veterina\u0308rmedizin","institution_ids":[]},{"raw_affiliation_string":"Institut fu\u0308r Mikrobiologie und Tierseuchen, Freie Universita\u0308t Berlin, Germany","institution_ids":["https://openalex.org/I75951250"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023633212","display_name":"A. L\u00fcbke","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"A. L\u00fcbke","raw_affiliation_strings":["Institut fu\u0308r Biochemie, SFB 344, Freie Universita\u0308t Berlin, D-14195 Berlin, Germany","Institut fu\u0308r Mikrobiologie und Tierseuchen, Fachbereich Veterina\u0308rmedizin","Institut fu\u0308r Mikrobiologie und Tierseuchen, Freie Universita\u0308t Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institut fu\u0308r Biochemie, SFB 344, Freie Universita\u0308t Berlin, D-14195 Berlin, Germany","institution_ids":["https://openalex.org/I75951250"]},{"raw_affiliation_string":"Institut fu\u0308r Mikrobiologie und Tierseuchen, Fachbereich Veterina\u0308rmedizin","institution_ids":[]},{"raw_affiliation_string":"Institut fu\u0308r Mikrobiologie und Tierseuchen, Freie Universita\u0308t Berlin, Germany","institution_ids":["https://openalex.org/I75951250"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5075504136"],"corresponding_institution_ids":["https://openalex.org/I75951250"],"apc_list":null,"apc_paid":null,"fwci":0.4815,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.59719126,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"42","issue":"1-10","first_page":"59","last_page":"63"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11688","display_name":"Microbial infections and disease research","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10873","display_name":"Bacterial Infections and Vaccines","score":0.003100000089034438,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13791","display_name":"Veterinary medicine and infectious diseases","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/3404","display_name":"Small Animals"},"field":{"id":"https://openalex.org/fields/34","display_name":"Veterinary"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/actinobacillus-pleuropneumoniae","display_name":"Actinobacillus pleuropneumoniae","score":0.9430000185966492},{"id":"https://openalex.org/keywords/glaesserella-parasuis","display_name":"Haemophilus parasuis","score":1.0},{"id":"https://openalex.org/keywords/pasteurella-multocida","display_name":"Pasteurella multocida","score":0.9509999752044678},{"id":"https://openalex.org/keywords/major-outer-membrane-protein","display_name":"major outer membrane protein","score":0.921999990940094},{"id":"https://openalex.org/keywords/porin","display_name":"porin","score":0.7419999837875366},{"id":"https://openalex.org/keywords/polyclonal-antibodies","display_name":"polyclonal antibodies","score":0.777999997138977},{"id":"https://openalex.org/keywords/cross-reactivity","display_name":"cross-reactivity","score":0.7929999828338623},{"id":"https://openalex.org/keywords/amino-acid-sequence-homology","display_name":"amino acid sequence homology","score":0.8550000190734863},{"id":"https://openalex.org/keywords/gram-negative-bacteria","display_name":"Gram-negative bacteria","score":0.5609999895095825}],"concepts":[{"id":"https://openalex.org/C146587185","wikidata":"https://www.wikidata.org/wiki/Q258248","display_name":"Bacterial outer membrane","level":4,"score":0.9368250370025635},{"id":"https://openalex.org/C2776796551","wikidata":"https://www.wikidata.org/wiki/Q310656","display_name":"Pasteurella multocida","level":3,"score":0.9240121841430664},{"id":"https://openalex.org/C2777317804","wikidata":"https://www.wikidata.org/wiki/Q67101192","display_name":"Porin","level":5,"score":0.8955725431442261},{"id":"https://openalex.org/C2780861368","wikidata":"https://www.wikidata.org/wiki/Q343332","display_name":"Actinobacillus pleuropneumoniae","level":3,"score":0.8414461016654968},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.7304832935333252},{"id":"https://openalex.org/C2780728835","wikidata":"https://www.wikidata.org/wiki/Q310714","display_name":"Actinobacillus","level":3,"score":0.7271966934204102},{"id":"https://openalex.org/C2776402342","wikidata":"https://www.wikidata.org/wiki/Q311275","display_name":"Haemophilus","level":3,"score":0.7209107875823975},{"id":"https://openalex.org/C956191","wikidata":"https://www.wikidata.org/wiki/Q930144","display_name":"Polyclonal antibodies","level":3,"score":0.5834177732467651},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5793985724449158},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.543740451335907},{"id":"https://openalex.org/C2779923002","wikidata":"https://www.wikidata.org/wiki/Q2477372","display_name":"Pasteurella","level":3,"score":0.4574543535709381},{"id":"https://openalex.org/C144647389","wikidata":"https://www.wikidata.org/wiki/Q423042","display_name":"Membrane protein","level":3,"score":0.44839397072792053},{"id":"https://openalex.org/C2777154767","wikidata":"https://www.wikidata.org/wiki/Q142666","display_name":"Pasteurellaceae","level":4,"score":0.4187653958797455},{"id":"https://openalex.org/C165525559","wikidata":"https://www.wikidata.org/wiki/Q224180","display_name":"Homology (biology)","level":3,"score":0.41715019941329956},{"id":"https://openalex.org/C2776925733","wikidata":"https://www.wikidata.org/wiki/Q1141979","display_name":"Haemophilus influenzae","level":3,"score":0.401228129863739},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.3207853436470032},{"id":"https://openalex.org/C10389963","wikidata":"https://www.wikidata.org/wiki/Q848328","display_name":"Serotype","level":2,"score":0.2972904145717621},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.2757355570793152},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.2452477216720581},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.24172687530517578},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.20897409319877625},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.11689546704292297},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09784942865371704},{"id":"https://openalex.org/C501593827","wikidata":"https://www.wikidata.org/wiki/Q12187","display_name":"Antibiotics","level":2,"score":0.08681058883666992}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001425","descriptor_name":"Bacterial Outer Membrane Proteins","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D001425","descriptor_name":"Bacterial Outer Membrane Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D006190","descriptor_name":"Haemophilus","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016415","descriptor_name":"Sequence Alignment","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":false},{"descriptor_ui":"D016977","descriptor_name":"Actinobacillus pleuropneumoniae","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D016979","descriptor_name":"Pasteurella multocida","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1439-0450.1995.tb00682.x","doi":"https://doi.org/10.1111/j.1439-0450.1995.tb00682.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1439-0450.1995.tb00682.x","pdf_url":null,"source":{"id":"https://openalex.org/S195337790","display_name":"Journal of Veterinary Medicine Series B","issn_l":"0931-1793","issn":["0931-1793","1439-0450"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Veterinary Medicine, Series B","raw_type":"journal-article"},{"id":"pmid:7483902","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7483902","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zentralblatt fur Veterinarmedizin. Reihe B. Journal of veterinary medicine. Series B","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.504800021648407,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1775749144","https://openalex.org/W1915185654","https://openalex.org/W1937456523","https://openalex.org/W1943682202","https://openalex.org/W1989495742","https://openalex.org/W2047841570","https://openalex.org/W2100837269","https://openalex.org/W2101108802","https://openalex.org/W2101190771","https://openalex.org/W2101787018","https://openalex.org/W2132591894","https://openalex.org/W2134822287","https://openalex.org/W2142692636","https://openalex.org/W2169287601"],"related_works":["https://openalex.org/W1989495742","https://openalex.org/W1991943392","https://openalex.org/W1991978310","https://openalex.org/W2638976470","https://openalex.org/W2345730448","https://openalex.org/W2437159194","https://openalex.org/W1969931616","https://openalex.org/W2168888585","https://openalex.org/W2157459193"],"abstract_inverted_index":{"A":[0],"polyclonal":[1],"antibody":[2],"against":[3],"the":[4,15,25,46,65,69],"35":[5,48],"kDa":[6,17,27,49,67,71],"major":[7,18,28],"outer-membrane":[8,19,29],"protein":[9,20,30,51,72],"of":[10,21,31,38,52,78],"Pasteurella":[11,53],"multocida":[12,54],"cross-reacted":[13],"with":[14,45,75],"40":[16,66],"Actinobacillus":[22],"pleuropneumoniae":[23],"and":[24,56,68,74],"42":[26,70],"Haemophilus":[32],"parasuis.":[33],"The":[34],"N-terminal":[35],"amino-acid":[36],"sequences":[37],"these":[39],"proteins":[40],"revealed":[41],"a":[42],"strong":[43],"homology":[44],"putative":[47],"porin":[50],"(66.7":[55],"76.2%,":[57],"respectively).":[58],"Significant":[59],"homologies":[60],"were":[61],"also":[62],"evident":[63],"between":[64],"(76.2%),":[73],"non-specific":[76],"porins":[77],"gram-negative":[79],"bacteria.":[80]},"counts_by_year":[],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}