{"id":"https://openalex.org/W2028201474","doi":"https://doi.org/10.1021/jo00054a035","title":"Asymmetric synthesis of the benzoquinoid ansamycin antitumor antibiotics: total synthesis of (+)-macbecin","display_name":"Asymmetric synthesis of the benzoquinoid ansamycin antitumor antibiotics: total synthesis of (+)-macbecin","publication_year":1993,"publication_date":"1993-01-01","ids":{"openalex":"https://openalex.org/W2028201474","doi":"https://doi.org/10.1021/jo00054a035","mag":"2028201474"},"language":"en","primary_location":{"id":"doi:10.1021/jo00054a035","doi":"https://doi.org/10.1021/jo00054a035","is_oa":false,"landing_page_url":"https://doi.org/10.1021/jo00054a035","pdf_url":null,"source":{"id":"https://openalex.org/S205050996","display_name":"The Journal of Organic Chemistry","issn_l":"0022-3263","issn":["0022-3263","1520-6904"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Organic Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035782410","display_name":"David Albert Evans","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David A. Evans","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073335566","display_name":"Scott J. Miller","orcid":"https://orcid.org/0000-0001-7817-1318","observed_orcids":["https://orcid.org/0000-0001-7817-1318"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Scott J. Miller","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5109503128","display_name":"Michael D. Ennis","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael D. Ennis","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4500,"currency":"USD","value_usd":4500},"apc_paid":null,"fwci":1.7435,"has_fulltext":false,"cited_by_count":90,"citation_normalized_percentile":{"value":0.84653556,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"58","issue":"2","first_page":"471","last_page":"485"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13971","display_name":"Isoquinoline Alkaloid Synthesis","score":0.3434999883174896,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13971","display_name":"Isoquinoline Alkaloid Synthesis","score":0.3434999883174896,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13859","display_name":"Organic Chemistry Synthesis Methods","score":0.19789999723434448,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13649","display_name":"Advanced Synthetic Organic Chemistry","score":0.11129999905824661,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ansamycins","display_name":"ansamycins","score":0.7200000286102295},{"id":"https://openalex.org/keywords/asymmetric-synthesis","display_name":"asymmetric synthesis","score":0.6710000038146973},{"id":"https://openalex.org/keywords/total-synthesis","display_name":"total synthesis","score":0.9940000176429749},{"id":"https://openalex.org/keywords/antitumor-antibiotics","display_name":"antitumor antibiotics","score":0.8939999938011169},{"id":"https://openalex.org/keywords/macrolide-antibiotics","display_name":"macrolide antibiotics","score":0.550000011920929},{"id":"https://openalex.org/keywords/natural-product-synthesis","display_name":"natural product synthesis","score":0.48899999260902405}],"concepts":[{"id":"https://openalex.org/C2778805511","wikidata":"https://www.wikidata.org/wiki/Q1713","display_name":"Citation","level":2,"score":0.7677753567695618},{"id":"https://openalex.org/C2778447006","wikidata":"https://www.wikidata.org/wiki/Q1156474","display_name":"Icon","level":2,"score":0.6286821365356445},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6209334135055542},{"id":"https://openalex.org/C518677369","wikidata":"https://www.wikidata.org/wiki/Q202833","display_name":"Social media","level":2,"score":0.45793819427490234},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.35412460565567017},{"id":"https://openalex.org/C136764020","wikidata":"https://www.wikidata.org/wiki/Q466","display_name":"World Wide Web","level":1,"score":0.31859198212623596},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1021/jo00054a035","doi":"https://doi.org/10.1021/jo00054a035","is_oa":false,"landing_page_url":"https://doi.org/10.1021/jo00054a035","pdf_url":null,"source":{"id":"https://openalex.org/S205050996","display_name":"The Journal of Organic Chemistry","issn_l":"0022-3263","issn":["0022-3263","1520-6904"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Organic Chemistry","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2025000583","https://openalex.org/W2002607171","https://openalex.org/W2950627862","https://openalex.org/W2029713542","https://openalex.org/W2068922694","https://openalex.org/W2952708213","https://openalex.org/W2951847518","https://openalex.org/W2118763154","https://openalex.org/W2016184195","https://openalex.org/W2953086293"],"abstract_inverted_index":{"ADVERTISEMENT":[0],"RETURN":[1],"TO":[2],"ISSUEPREVArticleNEXTAsymmetric":[3],"synthesis":[4,12],"of":[5,13,57,92,118],"the":[6,54,85,90,119,130,143,146,151,158,164],"benzoquinoid":[7],"ansamycin":[8],"antitumor":[9],"antibiotics:":[10],"total":[11],"(+)-macbecinDavid":[14],"A.":[15],"Evans,":[16],"Scott":[17],"J.":[18,25],"Miller,":[19],"and":[20,67,72,101,145,162,178,180],"Michael":[21],"D.":[22],"EnnisCite":[23],"this:":[24],"Org.":[26],"Chem.":[27],"1993,":[28],"58,":[29],"2,":[30],"471\u2013485Publication":[31],"Date":[32],"(Print):January":[33],"1,":[34],"1993Publication":[35],"History":[36],"Published":[37],"online1":[38],"May":[39],"2002Published":[40],"inissue":[41],"1":[42],"January":[43],"1993https://pubs.acs.org/doi/10.1021/jo00054a035https://doi.org/10.1021/jo00054a035research-articleACS":[44],"PublicationsRequest":[45],"reuse":[46],"permissionsArticle":[47],"Views1561Altmetric-Citations80LEARN":[48],"ABOUT":[49],"THESE":[50],"METRICSArticle":[51],"Views":[52],"are":[53,76,89],"COUNTER-compliant":[55],"sum":[56],"full":[58],"text":[59],"article":[60,124],"downloads":[61],"since":[62],"November":[63],"2008":[64],"(both":[65],"PDF":[66],"HTML)":[68],"across":[69],"all":[70],"institutions":[71],"individuals.":[73],"These":[74],"metrics":[75],"regularly":[77],"updated":[78,102],"to":[79,84],"reflect":[80],"usage":[81],"leading":[82],"up":[83],"last":[86],"few":[87],"days.Citations":[88],"number":[91],"other":[93],"articles":[94],"citing":[95],"this":[96],"article,":[97],"calculated":[98],"by":[99],"Crossref":[100,108],"daily.":[103],"Find":[104,154],"more":[105,155],"information":[106,156],"about":[107,142],"citation":[109],"counts.The":[110],"Altmetric":[111,159],"Attention":[112,160],"Score":[113,161],"is":[114,166],"a":[115,122,135],"quantitative":[116],"measure":[117],"attention":[120],"that":[121],"research":[123],"has":[125],"received":[126],"online.":[127],"Clicking":[128],"on":[129,157],"donut":[131],"icon":[132],"will":[133],"load":[134],"page":[136],"at":[137],"altmetric.com":[138],"with":[139,174],"additional":[140],"details":[141],"score":[144,165],"social":[147],"media":[148],"presence":[149],"for":[150],"given":[152],"article.":[153],"how":[163],"calculated.":[167],"Share":[168,183],"Add":[169],"toView":[170],"InAdd":[171],"Full":[172],"Text":[173],"ReferenceAdd":[175],"Description":[176],"ExportRISCitationCitation":[177],"abstractCitation":[179],"referencesMore":[181],"Options":[182],"onFacebookTwitterWechatLinked":[184],"InRedditEmail":[185],"Other":[186],"access":[187],"optionsGet":[188],"e-AlertscloseSupporting":[189],"Info":[190],"(1)\u00bbSupporting":[191],"Information":[192,194],"Supporting":[193],"Get":[195],"e-Alerts":[196]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}